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1795篇 您的检索式:作者名="Vaccaro"
    题名 作者 年代 出处 被引量
1急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI.Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS 2017中华神经外科疾病研究杂志2017,16,6:8
2Visual outcome after removal of silicone oil in patients undergoing retinectomy for complex retinal detachment显示文摘AIM:To evaluate the functional outcome after removal of silicone oil(ROSO)in patients undergoing retinectomy for complex retinal detachment.·METHODS:We performed a retrospective case note review of patients who underwent ROSO after retinectomy for complex retinal detachment.Patients with less than 6mo follow up and recurrent retinal detachment following ROSO were excluded.·RESULTS:Thirty-six patients were included.The mean best corrected visual acuity(BCVA)pre-ROSO was1.13 log MAR(SD 0.5).The mean BCVA 3mo following ROSO was 1.16 log MAR(SD 0.53),6mo following ROSO1.13(SD 0.63),and 12mo following ROSO 1.18(SD 0.69).At 12mo after ROSO,the BCVA improved in 38.9%of patients,remained unchanged in 25%,and deteriorated in 36.1%,although there was no statistical significant difference in BCVA after ROSO at 3,6 and 12mo(P=0.93).The size of retinectomy ranged from 15°to 270°(SD 53)and did not influence the visual outcome(P=0.11).·CONCLUSION:There was no statistically significant difference in BCVA between pre-and post-ROSO following retinectomy for complex retinal detachment.There was no statistical difference in visual outcome related to the size of the retinectomy.Roger Wong Marco De Luca Manoharan Shunmugam Tom Williamson Alistair Laidlaw Valeria Vaccaro 2016International Journal of Ophthalmology(English edition)2016,9,1:7
3Spinal fractures resulting from traumatic injuries显示文摘说明脊骨破裂和脊柱受伤的模式的机制的目的在伊朗的城市的人口由主要机制描绘了。脊柱受伤,缩短的损害分数,联系损害和病人的最后的命运的方法数据考虑脊柱受伤包括人口分布,机制和水平从 1999 ~ 2004 从伊朗的国家损伤注册表数据库被提取。有创伤的脊骨破裂的 619 个病人全部的结果 A 被识别,谁 68.5% 是男性。这些损害的山峰频率发生在 21-40 年年龄组。意外下降和道路交通碰撞(RTC ) 是针的破裂的最普通的机制(47.2% 和 44.1% ,分别地) 。RTC 趋于与意外下降相比发生在更年轻的病人。为针的骨折的最普通的针的区域是腰部的脊骨(53.63%) 。颈的脊骨破裂是显著地在 RTC 更普通,当腰部的脊骨破裂在意外下降是更普通的时(P < 0.001 ) 。171 的一个总数(27.6%) 病人们联系了非针的损害, 127 联系了极限损害,和 55 有的头损害。36 (5.6%) 病人们有针的绳索损害(SCI ) 。RTC 组的损害严厉分数比意外下降(P=0.002 ) 的显著地高。十五(4%) 病人们死于创伤的损害。死亡的率与意外下降相比在 RTC 是显著地更高的(5.1% 对 2.1% , P=0.039 ) 。结论针的破裂的模式类似于从发达国家报导的那些。RTC 趋于影响更年轻的年龄人口并且比意外下降与联系损害和死亡的更高的度被联系。因此预防的策略应该基于数字的减小和 RTC 的严厉。Heidari Pedram Zarei Mohammad Reza Rasouli Mohammad Reza Alexander R Vaccaro Rahimi-Movaghar Vafa 2010Chinese Journal of Traumatology2010,13,1:6
4Correlation of Posterior Ligamentous Complex Injury and Neurological Injury to Loss of Vertebral Body Height, Kyphosis, and Canal Compromise显示文摘Kristen Radcliff Brian W. Su Christopher K. Kepler Todd Rubin Adam L. Shimer Jeffrey A. Rihn James A. Harrop Todd J. Albert Alexander R. Vaccaro 2012Spine2012,,13:2
5Osteoporotic compression fractures of the spine; current options and considerations for treatment显示文摘David H. Kim Alexander R. Vaccaro 2006The Spine Journal2006,,5:2
6Metastatic pancreatic cancer: Is there a light at the end of the tunnel?显示文摘Due to extremely poor prognosis,pancreatic cancer(PDAC)represents the fourth leading cause of cancerrelated death in Western countries.For more than a decade,gemcitabine(Gem)has been the mainstay of first-line PDAC treatment.Many efforts aimed at improving single-agent Gem efficacy by either combining it with a second cytotoxic/molecularly targeted agent or pharmacokinetic modulation provided disappointing results.Recently,the field of systemic therapy of advanced PDAC is finally moving forward.Polychemotherapy has shown promise over single-agent Gem:regimens like PEFG-PEXG-PDXG and GTX provide significant potential advantages in terms of survival and/or disease control,although sometimes at the cost of poor tolerability.The PRODIGE 4/ACCORD 11 was the first phaseⅢtrial to provide unequivocal benefit using the polychemotherapy regimen FOLFIRINOX;however the less favorable safety profile and the characteristics of the enrolled population,restrict the use of FOLFIRINOX to young and fit PDAC patients.The nanoparticle albumin-bound paclitaxel(nab-Paclitaxel)formulation was developed to overcome resistance due to the desmoplastic stroma surrounding pancreatic cancer cells.Regardless of whether or not this is its main mechanisms of action,the combination of nabPaclitaxel plus Gem showed a statistically and clinically significant survival advantage over single agent Gem and significantly improved all the secondary endpoints.Furthermore,recent findings on maintenance therapy are opening up potential new avenues in the treatment of advanced PDAC,particularly in a new era in which highly effective first-line regimens allow patients to experience prolonged disease control.Here,we provide an overview of recent advances in the systemic treatment of advanced PDAC,mostly focusing on recent findings that have set new standards in metastatic disease.Potential avenues for further development in the metastatic setting and current efforts to integratenew effective chemotherapy regimens in earlier stages of disease(neoadjuvant,adjuvant,and multimodal approaches in both resectable and unresectable patients)are also briefly discussed.Vanja Vaccaro Isabella Sperduti Sabrina Vari Emilio Bria Davide Melisi Carlo Garufi Carmen Nuzzo Aldo Scarpa Giampaolo Tortora Francesco Cognetti Michele Reni Michele Milella 2015World Journal of Gastroenterology2015,21,16:2
7A new classification and guide for surgical treatment of spinal tuberculosis显示文摘E. Oguz A. Sehirlioglu M. Altinmakas C. Ozturk M. Komurcu C. Solakoglu A. R. Vaccaro 2008International Orthopaedics2008,,1:2
8国际脊髓损伤脊柱损伤基础数据集显示文摘收集脊柱损伤的信息对于脊髓损伤患者的诊断和治疗非常重要,设立脊髓损伤患者脊柱损伤基础数据集是为了规范脊柱损伤相关信息的收集方式和报告内容,学习并使用国际脊髓损伤脊柱损伤基础数据集,有助于规范和统一我国脊髓损伤患者脊柱损伤信息的收集,为相关治疗提供依据。本文将介绍国际脊髓损伤脊柱损伤基础数据集的研发过程,数据元素的内容以及数据编码的应用实例。Marcel F. Dvorak Peter C.Wing Michael G.Fehlings Alexander R. Vaccaro Eyal Itshayek Fin Biering-Sorensen Vanessa K.Noonan 王一吉(译) 周红俊(译) 李建军(译) 刘根林(译) 郑樱(译) 郝春霞(译) 张缨(译) 卫波(译) 康海琼(译) 逯晓蕾(译) 2014中国康复理论与实践2014,20,2:2
9Properties of agricultural aerosol released during wheat harvest threshing,plowing and sowing显示文摘This study shows for the first time a chemical and morphological characterization of agricultural aerosols released during three important agricultural operations:threshing,plowing and sowing.The field campaigns were carried out in the eastern part of the Po Valley,Italy,in summer and autumn 2009.The aerosol particles were sampled on quartz fiber filters and polytetrafluoroethylene membranes in order to allow Inductively Coupled Plasma Mass Spectrometry(ICP-MS)analysis and Scanning Electron Microscopy equipped with an Energy Dispersive X-ray Spectrometer(SEM-EDS)investigations,respectively.The organic carbon mass concentrations were measured with a Sunset Laboratory Dual-Optical Organic Carbone/Elemental Carbon(OCEC)Aerosol analyzer.The morphological and chemical analyses by SEM-EDS allowed recognizing four main particle classes:organic,silica,calcite and clay minerals.The organic particles contribute to both fine and coarse aerosol fractions up to ca.50%for all three agricultural activities.This was also confirmed by OCEC analysis for fine fraction.Most of the agricultural aerosols,about 60%,were single particles and the remaining 40%were agglomerations of particles.The ICP-MS results showed that threshing and plowing produce more aerosol particles than sowing,which was characterized by important amounts of clay minerals produced from land soils.Chiara Telloli Antonella Malaguti Mihaela Mircea Renzo Tassinari Carmela Vaccaro Massimo Berico 2014Journal of Environmental Sciences2014,26,9:2
10Ileocolic intussusception due to intestinal metastatic melanoma. Case report and review of the literature显示文摘Fernando A. Alvarez Matías Nicolás Jeremías Goransky Carlos A. Vaccaro Axel Beskow Demetrio Cavadas 2011International Journal of Surgery Case Reports2011,,6:2
11Molecular biology of cervical myelopathy and spinal cord injury:role of oligodendrocyte apoptosis显示文摘Kim D H Vaccaro A R Henderson F C Benzel E C 2003Spine J2003,3,:1
12The use of allograft bone in lumbar spine surgery 显示文摘Ehrler DM Vaccaro AR 2000Clin Orthop Relat Res2000,371,:1
13Rectal cacer:local recurrence after surgery without radiotherapy显示文摘 Vaccaro CA Benati ML 2001Dis Colon Rectum2001,44,3:1
14The use of allograft bone in lumbar spine surgery显示文摘Ehrler DM Vaccaro AR 2000Clin Orthop Relat Res2000,,371:1
15The surgical management of thoracolumbar injuries 显示文摘Singh K Vaccaro AR Eichenbaum MD 2004J Spinal Cord Med2004,27,2:1
16Molecular biology of cervical myelopathy and spinal cord injury:role of oligodendrocyte apoptosis显示文摘Kim DH Vaccaro AR Henderson FC 2003Spinal J2003,3,6:1
17Enhancement of stability following anterior cervical corpeetomy:A biomechanical study显示文摘Singh K Vaccaro A R Kim J 2004Spine2004,29,4:1
18A new classification of thoracolumbar injuries:the importance of injury morphology,the integrity of the posterior ligamentous complex, and neurologic status显示文摘Vaccaro AR Lehman RA Jr Hurlbert R J 2005Spine2005,30,20:1
19Enhancement of sta- bility following anterior cervical corpectomy: a biome- chanical study 显示文摘Singh K Vaccaro AR Kim J 2004Spine ( Phila Pa 1976 )2004,29,8:1
20Osteoporotic compression fractures of the spine,current options and considerations for treatment显示文摘Kim DH Vaccaro AR 0,,05:1
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