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2篇 您的检索式:作者名="Valentina Apuzzi"
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1Management of chronic heart failure:Role of home echocardiography in monitoring care programs显示文摘AIM:To identify a possible role of home echocardiography for monitoring chronic heart failure(CHF)patients.METHODS:We prospectively investigated 118 patients hospitalized during the last year for CHF who could not easily reach the pertaining District Healthcare Center.The patients were followed up with 2 home management programs:one including clinical and electrocardiographic evaluations and also periodic home echocardiographic examinations(group A),the other including clinical and electrocardiographic evaluations only(group B).RESULTS:At the end of the 18-mo follow-up no significant differences were observed between the 2 groups as regards the primary endpoint:rehospitalization occurred in 4 patients of the group A and in 6 patients of the group B;major cardiovascular events occurred in 2 and in 3 patients,respectively.No significant differences were observed with respect to the secondary endpoints:one vascular event appeared in both the groups,3 cardiovascular deaths occurred in group A and 2 in group B.No significant differences were observed between the 2 groups as regards the composite endpoint of death plus hospitalization.CONCLUSION:Home echocardiography for monitoring of CHF patients does not improve the cardiovascular endpoints.In our CHF patients,a low incidence of vascular events was observed.Silvia Soreca Sergio Aprile Andrea Cardone Giovanni Carella Biagio Fimiani Franco Guarnaccia Giosuè Santoro Valentina Apuzzi Giorgio Bosso Antonio Valvano Giovanni Zito Ugo Oliviero 2012World Journal of Cardiology2012,4,3:1
2Impaired diastolic function in nave untreated human immunodeficiency virus infected patients显示文摘AIM:To evaluate cardiac function and structure in un-treated human immunodeficiency virus(HIV) patients without clinical evidence of cardiovascular disease.METHODS:Fifty-three nave untreated HIV-infected patients and 56 healthy control subjects underwent clinical assessment,electrocardiography(ECG) and echocardiography,including tissue doppler imaging.Moreover,a set of laboratory parameters was obtained from all subjects,including HIV-RNA plasma levels,CD4 cell counts and tumor necrosis factor-α levels.RESULTS:The two groups showed normal ECG traces and no differences regarding systolic morphologic parameters.In contrast,a higher prevalence of left ventricular diastolic dysfunction(abnormal relaxation or pseudonormal filling pattern) was found in the HIV patients(36% vs 9% in patients and controls,respec-tively,P <0.001).CONCLUSION:Subclinical cardiac abnormalities ap-pear in an early stage of the HIV infection,indepen-dent of antiretroviral therapy.The data suggest that HIV per se plays a role in the genesis of diastolic dys-function.Ugo Oliviero Giovanni Bonadies Giorgio Bosso Maria Foggia Valentina Apuzzi Mariarosaria Cotugno Antonio Valvano Enrico Leonardi Guglielmo Borgia Giuseppe Castello Raffaele Napoli Luigi Saccà 2010World Journal of Cardiology2010,2,4:0
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