|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016，3，1： | 6 |
| 2 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 3 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 4 | The interactions between signal-setting optimization and assignment:Background and preliminary results 显示文摘 | Van Vuren T Smith M J Van Vliet D | 1987 | Transportation Research Record1987，11，42： | 2 |
| 5 | Effect of hepatic artery embolization on liver hypertrophy response in a rabbit liver VX2tumor model显示文摘BACKGROUND:Portal vein embolization not only induces hypertrophy of the non-embolized liver,but also enhances tumor growth.The latter could be prevented by embolizing the hepatic arteries supplying the tumor-bearing liver segments.This study aimed to determine the effects of transcatheter arterial embolization(TAE)on tumor volume and liver regeneration in a rabbit VX2 tumor model.METHODS:Twenty-three rabbits underwent subcapsular tumor implantation with a VX2 tumor.Two weeks after implantation,18 rabbits were used for TAE experiments,5were for sham controls.Tumor response and liver regeneration response of the embolized cranial and non-embolized caudal liver lobes were assessed by CT volumetry,liver to body weight index,and the amount of proliferating hepatocytes.RESULTS:All super-selective arterial tumor embolization procedures were performed successfully.Despite embolization,the tumor volume increased after an initial steady state.The tumor volume after embolization was smaller than that of the sham group,but this difference was not significant.Massive necrosis of the tumor,however,was seen after embolization,without damage of the surrounding liver parenchyma.There was a significant atrophy response of the tumor bearing cranial lobe after super-selective arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized,caudal lobe.This regeneration response was confirmed histologically by a significantly higher number of proliferating hepatocytes on the Ki-67 stained slides.CONCLUSIONS:Super-selective,bland arterial coil embolization causes massive necrosis of the tumor,despite increase of volume on CT scan.Atrophy of the tumor bearing liver lobe is seen after arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized lobe,despite absence of histological damage of the tumor-surrounding liver parenchyma. | Krijn P van Lienden Lisette T Hoekstra Jessica D van Trigt Joris J Roelofs Otto M van Delden Thomas M van Gulik | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 2 |
| 6 | Agricultural nutrient losses to surface water in the Netherlands:Impact, strategies, and perspectives显示文摘 | Van Der Molen D T Breeuwsma A Boers P C M | 1998 | Journal of Environmentol Quality1998，27，1： | 1 |
| 7 | New constraints on the sources and behavior of neodymium and hafnium in seawater from Pacific Ocean ferromanganese crusts显示文摘 | VAN DE FLIERDT T FRANK M LEE D C | 2004 | Geochim et Cosmochim Acta2004，68，19： | 1 |
| 8 | Quenching of giant hysteresis effects in La1 - zYzHx switchable mirrors 显示文摘 | van Gogh A T M Nagengast D G Kooij E S | 2000 | Physical Review Letters2000，85，10： | 1 |
| 9 | Newly discovered coronavirus as the primary cause of severe acute respiratory synd rome 显示文摘 | Kuiken T Fouchier RA Schutten M Rimmelzwaan GF van Amerongen G van Riel D | 2003 | Lance t2003，362，： | 1 |
| 10 | Simian rotaviruses possess divergent gene constellations that originated from interspecies transmission and reas- sortment 显示文摘 | Matthijnssens J Taraporewala Z F Yang H Rao S Yuan L Cao D Hoshino Y Mertens P P Carner G R McNeal M Sestak K Van Ranst M Patton J T | 2010 | J Virol2010，84，4： | 1 |
| 11 | Integration of a 1MHz converter with active and passive stages显示文摘 | van Wyk J D de Rooij M A | 2001 | IEEE APEC2001，，： | 1 |
| 12 | Blends of amide modifiedpolybutylene terephthalate and polycarbonate:transesterification and degradation显示文摘 | Pluimers D T Bussink J | 1997 | Polymer1997，38，12： | 1 |
| 13 | Oral immunization of native and primed animals with transgenic potato tubers expression LT-B显示文摘 | Lauterslager T G M Florack D E A Van der Wal T J | 2001 | Vaccine2001，19，： | 1 |
| 14 | Effects of biotin and high copper levels on performance and inmmune response of weanling pigs显示文摘 | Kornegay E T van Heugten P H L indemann M D | 1989 | J Anim Sci1989，67，6： | 1 |
| 15 | Uncertainty analysis of a spatial habitat suitability model and implications for ecological management of water bodies显示文摘 | Van der Lee G E M Van der Molen D T Van den Boogaard H F P et al | 2006 | Landsc Ecol2006，21，7： | 1 |
| 16 | A geneexpression signature as a predictor of survival in breast cancer显示文摘 | van de Vijver M J He Y D van't Veer L J | 2002 | N Eng J Med2002，347，： | 1 |
| 17 | AMP-Activated Protein Kinase Beta Subunit Tethers Alpha and Gamma Subunits via Its C-Terminal Sequence(186-270)显示文摘 | Iseli T J Walter M van D B J | 2005 | J Biol Chem2005，280，13： | 1 |
| 18 | Nodoventricular accessory pathways in PRKAG2-dependent familial preexcitation syndrome reveal a disorder incardiac development显示文摘 | Tan H L van der Wal A C Campian M E Kruyswijk H H Bram T H J van Doorn D J | 2008 | Circ Arrhythm Electrophysiol2008，1，： | 1 |
| 19 | Molecular dynamics simulations of laser-induced incandescence of soot using an extended reaxff reactive force field显示文摘 | Amar M K Adri C T van D Alexei Y | 2010 | J Phys Chem A2010，114，12： | 1 |
| 20 | Hyperbranched polyesteramides-- new dendritic polymers 显示文摘 | Muscat D van Benthem R A T M | 2001 | Top Curr Chem2001，212，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员