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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014,20,46: | 21 |
| 2 | Association of smoking, alcohol drinking and dietary factors with esophageal cancer in high- and low-risk areas of Jiangsu Province, China显示文摘瞄准:到环境的 main 和在食道的癌症(EC ) 说明地区性的差别的生活方式因素在江苏省的低风险、高风险的区域冒的风险的学习,中国。方法:自从 2003,基于人口的盒子控制研究同时被进行了在低风险(Ganyu 县) 并且高风险(Dafeng 县) 江苏省的区域,中国。使用相同协议和 pre-tested 标准化了问询表,跟随写的知情同意,合格题目被询问他们 EC 的潜在的决定因素的详细信息包括人口统计的信息,社会经济的地位,生活条件,疾病历史,家庭癌症历史,吸烟,酒精喝酒,饮食的习惯,频率,食物摄取的数量,等等。有最大的可能性评价的有条件的逻辑回归被用来获得机会比率(或) 并且 95 % 信心间隔(95% CI ) ,在为潜力的调整以后,反对失败。结果:在进行中的学习的初步的分析,我们招募了在 Ganyu 的在 Dafeng 的 291 个盒子和 240 个盒子和控制分别地。在低风险、高风险的区域, EC 相反地与社会经济的地位被联系,例如教育的水平,经过经济地位和身体团索引。然而,这疾病在有癌症的家庭历史或在过去的 10 年里遇到了不幸的那些之中是更经常的。EC 在吸烟者,白酒喝酒者和快食客之中也是更经常的。而且,有在吸烟,酒精喝酒和尽管有在低风险、高风险的区域的这些风险因素的类似的流行的 EC 风险之间的协会的一个地理变化。吸烟并且吸烟的剂量反应关系联系了变量,例如首先吸烟,持续时间和数量的年龄在高风险的区域仅仅是明显的。相反,在 EC 上喝的酒精的效果上的一种剂量反应关系仅仅在低风险的区域被观察。结论:环境风险因素,可能和基因因素和基因环境的相互作用是为在江苏省的这个高风险的坡度的主要原因,中国。 | Ming Wu Jin-Kou Zhao Xiao-Shu Hu Pei-Hua Wang Yu Qin Yin-Chang Lu Jie Yang Ai-Min Liu De-Lin Wu Zuo-Feng Zhang Kok J Frans Pieter van't Veer | 2006 | World Journal of Gastroenterology2006,12,11: | 18 |
| 3 | Q-switched and mode-locked Er-doped fiber laser using PtSe2 as a saturable absorber显示文摘We report a passively Q-switched and mode-locked erbium-doped fiber laser(EDFL) based on PtSe_2, a new two-dimensional material, as a saturable absorber(SA). Self-started Q-switching at 1560 nm in the EDFL was achieved at a threshold pump power of 65 mW, and at the maximum pump power of 450 m W, the maximum single Q-switched pulse energy is 143.2 n J. Due to the polarization-dependent characteristics of the PtSe_2-based SA, the laser can be switched from the Q-switched state to the mode-locked state by adjusting the polarization state. A mode-locked pulse train with a repetition rate of 23.3 MHz and a pulse width of 1.02 ps can be generated when the pump power increases to about 80 m W, and the stable mode-locked state is maintained until the pump power reaches its maximum 450 m W. The maximum single mode-locked pulse energy is0.53 nJ. This is the first time to our knowledge that successful generation of stable Q-switched and mode-locked pulses in an Er-doped fiber laser has been obtained by using PtSe_2 as a saturable absorber. | KANG ZHANG MING FENG YANGYANG REN FANG LIu XINGSHUO CHEN JIE YANG XIAO-QING VAN FENG SONG JIANGUO TIAN | 2018 | Photonics Research2018,6,9: | 10 |
| 4 | Oxidation of As(Ⅲ) by potassium permanganate显示文摘The oxidation of As(Ⅲ) with potassium permanganate was studied under conditions including pH, initial As(Ⅲ) concentration and dosage of Mn(VII). The results have shown that potassium permanganate was an effective agent for oxidation of As(Ⅲ) in a wide pH range. The pH value of tested water was not a significant factor affecting the oxidation of As(Ⅲ) by Mn(VII). Although theoretical redox analyses suggest that Mn(VII) should have better performance in oxidization of As(Ⅲ) within lower pH ranges, the experimental results show that the oxidation effciencies of As(Ⅲ) under basic and acidic conditions were similar, which may be due to the adsorption of As(Ⅲ) on the Mn(OH)2 and MnO2 resulting from the oxidation of As(Ⅲ). | LI Na FAN Maohong Van Leeuwen Johannes Saha Basudeb YANG Hongqun HUANG C. P. | 2007 | Journal of Environmental Sciences2007,19,7: | 10 |
| 5 | A Marine or Continental Nature of the Deltas in the Early Cretaceous Lingshandao Formation--Evidences from Trace Elements显示文摘Objective A succession with well-developed soft-sediment deformation structures and well-exposed gravity-flow deposits in the Early Cretaceous Lingshandao Formation has caused considerable controversy on whether the nondisputed deltaic environment was marine or continental.This dispute cannot be solved by mere sedimentological analysis and,moreover,too few fossils are present to be decisive.The main objective of the present contribution | YANG Renchao FAN Aiping HAN Zuozhen A.J.(Tom)VAN LOON | 2017 | Acta Geologica Sinica(English Edition)2017,91,1: | 10 |
| 6 | Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE显示文摘Multiple sclerosis(MS)is a chronic inflammatory disease of the central nervous system(CNS)in which the immune system damages the protective insulation surrounding the nerve fibers that project from neurons.A hallmark of MS and its animal model,experimental autoimmune encephalomyelitis(EAE),is autoimmunity against proteins of the myelin sheath.Most studies in this field have focused on the roles of CD4^(+)T lymphocytes,which form part of the adaptive immune system as both mediators and regulators in disease pathogenesis.Consequently,the treatments for MS often target the inflammatory CD4^(+)T-cell responses.However,many other lymphocyte subsets contribute to the pathophysiology of MS and EAE,and these subsets include CD8^(+)T cells and B cells of the adaptive immune system,lymphocytes of the innate immune system such as natural killer cells,and subsets of innate-like T and B lymphocytes such asγδT cells,natural killer T cells,and mucosal-associated invariant T cells.Several of these lymphocyte subsets can act as mediators of CNS inflammation,whereas others exhibit immunoregulatory functions in disease.Importantly,the efficacy of some MS treatments might be mediated in part by effects on lymphocytes other than CD4^(+)T cells.Here we review the contributions of distinct subsets of lymphocytes on the pathogenesis of MS and EAE,with an emphasis on lymphocytes other than CD4^(+)T cells.A better understanding of the distinct lymphocyte subsets that contribute to the pathophysiology of MS and its experimental models will inform the development of novel therapeutic approaches. | Luc Van Kaer Joshua L.Postoak Chuan Wang Guan Yang Lan Wu | 2019 | Cellular & Molecular Immunology2019,16,6: | 10 |
| 7 | Thermal-responsive genetic and epigenetic regulation of DAM cluster controlling dormancy and chilling requirement in peach floral buds显示文摘The Dormancy-associated MADS-box(DAM)gene cluster in peach serves as a key regulatory hub on which the seasonal temperatures act and orchestrate dormancy onset and exit,chilling response and floral bud developmental pace.Yet,how different temperature regimes interact with and regulate the six linked DAM genes remains unclear.Here,we demonstrate that chilling downregulates DAM1 and DAM3–6 in dormant floral buds with distinct patterns and identify DAM4 as the most abundantly expressed one.We reveal multiple epigenetic events,with tri-methyl histone H3 lysine 27(H3K27me3)induced by chilling specifically in DAM1 and DAM5,a 21-nt sRNA in DAM3 and a ncRNA induced in DAM4.Such induction is inversely correlated with downregulation of their cognate DAMs.We also show that the six DAMs were hypermethylated,associating with the production of 24-nt sRNAs.Hence,the chilling-responsive dynamic of the different epigenetic elements and their interactions likely define distinct expression abundance and downregulation pattern of each DAM.We further show that the expression of the five DAMs remains steadily unchanged or continuously downregulated at the ensuing warm temperature after chilling,and this state of regulation correlates with robust increase of sRNA expression,H3K27me3 and CHH methylation,which is particularly pronounced in DAM4.Such robust increase of repressive epigenetic marks may irreversibly reinforce the chillingimposed repression of DAMs to ensure flower-developmental programming free from any residual DAM inhibition.Taken together,we reveal novel information about genetic and epigenetic regulation of the DAM cluster in peach,which will be of fundamental significance in understanding of the regulatory mechanisms underlying chilling requirement and dormancy release,and of practical application for improvement of plasticity of flower time and bud break in fruit trees to adapt changing climates. | Hong Zhu Pao-Yang Chen Silin Zhong Chris Dardick Ann Callahan Yong-Qiang An Steve van Knocker Yingzhen Yang Gan-Yuan Zhong Albert Abbott Zongrang Liu | 2020 | Horticulture Research2020,7,1: | 9 |
| 8 | The Or Gene Enhances Carotenoid Accumulation and Stability During Post-Harvest Storage of Potato Tubers显示文摘在主食庄稼的维生素原 A 类胡萝卜素不在存储期间是很稳定的,他们的损失损害营养的质量。阐明位于类胡萝卜素累积和稳定性下面的基本机制,我们调查了表示了花椰菜橘子的转基因的土豆 tubers (或) 基因。我们发现 Or transgene 不仅支持了叶红素水平的保留,而且连续地在冷存储的 5months 期间刺激了它的累积。相反,类胡萝卜素的增加的层次都没在存储的一样的时期期间在向量唯一的控制或一个黄肉的变化的 tubers 被观察。增加的类胡萝卜素累积被发现与扣押的 lipoproteincarotenoid 的形成被联系结构,以及与提高的许多 phytoene synthase,在类胡萝卜素 biosynthetic 小径的关键酶。而且,存储的维生素原 A 类胡萝卜素被显示在模仿的消化期间稳定并且为由人的肠的吸收性的房间的举起可存取。Proteomic 分析识别了蛋白质的三个主要的功能的组(即热吃惊蛋白质, glutathione-S-transferases,和糖类新陈代谢的蛋白质) 那在或调整类胡萝卜素累积是潜在地重要的。我们的结果证明类胡萝卜素隐遁能力的那条规定是类胡萝卜素稳定性被调整的重要机制。我们的调查结果建议在主食庄稼的合适的水池结构形成的那正式就职可以向庄稼提供在植物生长和收获以后的存储期间支持或稳定维生素原 A 累积的一个唯一的能力。 | Li Li Yong Yang Qiang Xu Katherine Owsiany Ralf Welsch Chureeporn Chitchumroonchokchai Shan Lu Joyce Van Eck Xiu-Xin Deng Mark Failla Theodore W. Thannhauser | 2012 | Molecular Plant2012,5,2: | 8 |
| 9 | Siliceous Cementation of Chlorite-Coated Grains in the Permian Sandstone Gas Reservoirs,Ordos Basin显示文摘Objective It has long been controversial that whether authigenic chlorite coatings in sandstone reservoirs can prevent precipitation of siliceous cements.It is commonly believed that chlorite coatings(also called chlorite films,chlorite linings,or chlorite rims)may prevent quartz overgrowth,and thus help the preservation of original pores in sandstone reservoirs.Recently,however,this assumption has been challenged by reservoir geologists.This dispute cannot be solved by mere analysis of thin sections,nor by chemical equations and diagenesis analysis.The main objective of the present contribution is to shed light on | FAN Aiping YANG Renchao LI Jinbu ZHAO Zhongjun A.J.(Tom) VAN LOON | 2017 | Acta Geologica Sinica(English Edition)2017,91,3: | 5 |
| 10 | Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury显示文摘 | Yumiko Imai Keiji Kuba G. Greg Neely Rubina Yaghubian-Malhami Thomas Perkmann Geert van Loo Maria Ermolaeva Ruud Veldhuizen Y.H. Connie Leung Hongliang Wang Haolin Liu Yang Sun Manolis Pasparakis Manfred Kopf Christin Mech Sina Bavari J.S. Malik Peiris Ar | 2008 | Cell2008,,2: | 4 |
| 11 | The Soil-Borne Identity and Microbiome-Assisted Agriculture:Looking Back to the Future显示文摘Looking forward includes looking back every now and then.In 2007,David Weller looked back at 30 years of biocontrol of soil-borne pathogens by Pseudomonas and signified that the progress made over decades of research has provided a firm foundation to formulate current and future research questions.It has been recognized for more than a century that soil-borne microbes play a significant role in plant growth and health.The recent application of high-throughput omics technologies has enabled detailed dissection of the microbial players and molecular mechanisms involved in the complex interactions in plant-associated microbiomes.Here,we highlight old and emerging plant microbiome concepts related to plant disease control,and address perspectives that modern and emerging microbiomics technologies can bring to functionally characterize and exploit plant-associated microbiomes for the benefit of plant health in future microbiome-assisted agriculture. | Peter A.H.M.Bakker Roeland L.Berendsen Johan A.Van Pelt Gilles Vismans Ke Yu Erqin Li Sietske Van Bentum Sanne W.M.Poppeliers Juan J.Sanchez Gil Hao Zhang Pim Goossens Ioannis A.Stringlis Yang Song Ronnie de Jonge CornéM.J.Pieterse | 2020 | Molecular Plant2020,13,10: | 3 |
| 12 | Methodology of the Global Adult Tobacco Survey in China, 2010显示文摘INTRODUCTION The Global Adult Tobacco Survey (GATS) is a component of Global Tobacco Surveillance System (GTSS) under auspices of the Bloomberg philanthropy and the Bill and Melinda Gates Foundation. | JASON HSIA GONG-HUAN YANG QIANG LI LIN XIAO VAN YANG YAN-WEI WO SAMIRAASMA | 2010 | Biomedical and Environmental Sciences2010,23,6: | 3 |
| 13 | Surface functionalized N-C-TiO_(2)/C nanocomposites derived from metal-organic framework in water vapour for enhanced photocatalytic H generation显示文摘Surface-functionalized nitrogen/carbon co-doped polymorphic TiO_(2) phase junction nanoparticles uniformly distributed in porous carbon matrix were synthesized by a simple one-step pyrolysis of titanium based metal-organic framework(MOF),NH_(2)-MIL^(-1)25(Ti) at 700℃ under water vapour atmosphere.Introducing water vapour during the pyrolysis of NH_(2)-MIL^(-1)25(Ti) not only functionalizes the derived porous carbon matrix with carboxyl groups but also forms additional oxygen-rich N like interstitial/intraband states lying above the valence band of TiO2 along with the self-doped carbo n,which further narrows the energy band gaps of polymorphic TiO2 nanoparticles that enhance photocatalytic charge transfer efficiency.Without co-catalyst,sample N-C-TiO2/CArW demonstrates H_(2) evolution activity of 426 μmol gcat-1h^(-1),which remarkably outperforms commercial TiO_(2)(P-25) and N-C-TiO_(2)/CAr with a 5-fold and 3-fold H_(2) generation,respectively.This study clearly shows that water vapour atmosphere during the pyrolysis increases the hydrophilicity of the Ti-MOF derived composites by functionalizing porous carbon matrix with carboxylic groups,as well as enhancing the electrical conductivity and charge transfer efficiency due to the formation of additional localized oxygen-rich N like interstitial/intraband states.This work also demonstrates that by optimizing the anatase-rutile phase composition of the TiO2 polymorphs,tuning the energy band gaps by N/C co-doping and functionalizing the porous carbon matrix in the N-C-TiO2/C nanocomposites,the photocatalytic H_(2) generation activity can be further enhanced. | Mian Zahid Hussain Zhuxian Yang Bart van der Linden Zheng Huang Quanli Jia Erik Cerrato Roland A.Fischer Freek Kapteijn Yanqiu Zhu Yongde Xia | 2021 | Journal of Energy Chemistry2021,30,6: | 3 |
| 14 | Azithromycin inhibits neutrophil accumulation in airways by affecting interleukin- 17 downstream signals显示文摘 | Nguyen Van Luu Yang Jiong Qu Xue-ju Guo Ming Wang Xin Xian Qiao-yang Tang Zhi-jiao Huang Zhi-xiang Wang Yong | 2012 | Chinese Medical Journal2012,,3: | 3 |
| 15 | Proteasome inhibitor carfilzomib interacts synergistically with histone deacetylase inhibitor vorinostat in Jurkat T-leukemia cells显示文摘在现在的学习,我们在 Jurkat T 白血病房间调查了在 proteasome 禁止者 carfilzomib (CFZ ) 和 histone deacetylaseinhibitor vorinostat 之间的相互作用。到 CFZ 与的最低限度地致命的集中的细胞的 Coexposure 很, vorinostat 的 lowconcentration 导致了 synergistic antiproliferative 效果并且在 Jurkat T-leukemiacells 提高了 apoptosis ,与严厉地增加的反应的氧种( ROS )伴随了,在 mitochondrial membranepotential ( MMP )的惹人注目的减少,细胞色素 c 的增加的版本, caspase-9 和-3,和 PARP.The 的劈开的提高的激活联合了 Jurkat 细胞的处理与 ROS 预先对待而且, NAC 也在 apoptotic 房间导致了显著减小,显示为由联合处理的 increasedROS 产生的一个关键角色。另外,联合了逮捕的处理在 G 2-M 的房间周期阶段。这些结果暗示 CFZ 在 Jurkat T 白血病房间与 vorinostat synergistically 交往了,哪个有 vorinostat 的 carfilzomib 的联合可以在对待 T 房间代表新奇策略的 raisedthe 可能性白血病。 | Minjie Gao Lu Gao Yi Tao Jun Hou Guang Yang Xiaosong Wu Hongwei Xu Van S. Tompkins Ying Han Huiqun Wu Fenghuang Zhan Jumei Shi | 2014 | Acta Biochimica et Biophysica Sinica2014,46,6: | 3 |
| 16 | Comprehensive scan for nonmagnetic Weyl semimetals with nonlinear optical response显示文摘First-principles calculations have recently been used to develop comprehensive databases of nonmagnetic topological materials that are protected by time-reversal or crystalline symmetry.However,owing to the low symmetry requirement of Weyl points,a symmetry-based approach to identifying topological states cannot be applied to Weyl semimetals(WSMs).To date,WSMs with Weyl points in arbitrary positions are absent from the well-known databases. | Qiunan Xu Yang Zhang Klaus Koepernik Wujun Shi Jeroen van den Brink Claudia Felser Yan Sun | 2020 | npj Computational Materials2020,,1: | 3 |
| 17 | Anaphylaxis and generalized urticaria from eating Chinese bayberry fruit显示文摘Chinese bayberry Myrica rubra is a very popular fruit in southeastern China.In spite of its wide consumption,no allergies to this fruit have been reported previously.Here we report on a 40-year-old woman suffering from anaphylaxis to Chinese bayberry fruit.Prick-prick skin tests revealed strong reactions to fresh Chinese bayberry fruits as well as to peach,and weaker reactions to some other fruits including apple,melon,and banana.ImmunoCAP analysis revealed identical titers of specific IgE(4.3 kU A /L) to peach extract and its lipid transfer protein(LTP,rPru p 3),which was confirmed by detection of a 9 kD band following immunoblotting.Immunoblot analysis with Chinese bayberry extract gave bands of 22,45,and 90 kD,but no 9 kD band was recognized.There was also no evidence of LTP recognition for loquat(36 kD) or melon(24 kD).This first report of a severe allergic reaction to Chinese bayberry fruit in a patient with LTP-mediated peach allergy indicates that other as yet unidentified non-pollen related fruit allergens are involved in this new severe fruit allergy. | Hui-ying WANG Zhong-shan GAO Zhao-wei YANG Jing-xin SHAO Xiu-zhen ZHAO Yu DAI Ronald VAN REE | 2012 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2012,13,10: | 3 |
| 18 | Time-Series Modeling and Prediction of Global Monthly Absolute Temperature for Environmental Decision Making显示文摘概括的 A,结构,时间系列建模框架被开发分析绝对表面温度的每月的记录,最重要的环境参数之一,使用 deterministicstochastic 联合了(DSC ) 来临。尽管框架的发展基于全球数据集的变化模式的描述,方法论能被用于任何每月绝对的温度记录。确定的进程被用来描绘全球趋势的变化模式和温度信号的周期的摆动,分别地,当随机的进程被采用说明在温度信号的任何留下的模式时,包含多项式函数和 Fourier 方法,包含综合移动一般水准( SARIMA )建模的季节的 autoregressive 。每月全球的表面温度的预言在用 DSC 模型的第 21 世纪的第二十年期间证明全球温度将继续多半升起在两次过去的 150 年的平均的率。DSC 模型系统地执行很好对的预言精确性表演的评估选择了另外的作者的模型,当结合时,建议 DSC 当模特儿另外的 ecoenvironmental 模型,能被用作一个补加的工具为短期(10 年) 环境计划和决策。 | YE Liming YANG Guixia Eric VAN RANST TANG Huajun | 2013 | Advances in Atmospheric Sciences2013,30,2: | 3 |
| 19 | An Upward Shallowing Succession of Gravity Flow Deposits in the Early Cretaceous Lingshandao Formation,Western Yellow Sea显示文摘Objective Several well-exposed gravity flow deposits in the Early Cretaceous Lingshandao Formation provide a rare opportunity to study deep-water processes.The main objective of this work is to establish the spatial and temporal relationships between the various gravity flow deposits,and thus to establish their sequence stratigraphic patterns and depositional conditions. | YANG Renchao FAN Aiping HAN Zuozhen A.J.(Tom) van Loon | 2016 | Acta Geologica Sinica(English Edition)2016,90,4: | 3 |
| 20 | Predicting the Transition between Upper and Lower Bainite via a Gibbs Energy Balance Approach显示文摘The transition temperature between upper bainite and lower bainite is calculated with an extended Gibbs energy balance model, which is able to quantitatively describe the evolution of carbon supersaturation within bainitic ferrite sheaves during the entire thickening process. The nucleation rate of intra-lath cementite precipitation on a dislocation is calculated based on of the degree of carbon supersaturation.Upper bainite and lower bainite are thus distinguished by the effective nucleation density and therefore a numerical criterion can be set to define the transition. The model is applied to Fe-xC-1Mn/2Mn/1 Mo ternary alloys. Results show that the transition temperature increases with bulk carbon content at lower carbon concentration but decreases in the higher carbon region. This prediction agrees very well with the experimental observations in Mn and Mo alloyed systems. Moreover, the highest transition temperature and the carbon content at which it occurs in the Fe-xC-2Mn system are in good agreement with reported experimental data. The inverse 'V' shaped character of the carbon concentration–transition temperature curve indicates two opposite physical mechanisms operating at the same time. An analysis is carried out to provide an explanation. | Zenan Yang Wei Xu Zhigang Yang Chi Zhang Hao Chen Sybrand van der Zwaag | 2017 | Journal of Materials Science & Technology2017,33,12: | 2 |