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423篇 您的检索式：作者名="Vander W"

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	题名	作者	年代	出处	被引量
1	Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy显示文摘AIM: To examine DNA methylation profiles in a longitudinal comparison of pre-diabetes mellitus(Pre-DM) subjects who transitioned to type 2 diabetes mellitus(T2DM).METHODS: We performed DNA methylation study in bisulphite converted DNA from Pre-DM(n = 11) at baseline and at their transition to T2 DM using Illumina Infinium Human Methylation27 Bead Chip, that enables the query of 27578 individual cytosines at Cp G loci throughout the genome, which are focused on the promoter regions of 14495 genes.RESULTS: There were 694 Cp G sites hypomethylated and 174 Cp G sites hypermethylated in progression from Pre-DM to T2 DM, representing putative genes involved in glucose and fructose metabolism, inflammation, oxidative and mitochondrial stress, and fatty acid metabolism. These results suggest that this high throughput platform is able to identify hundreds of prospective Cp G sites associated with diverse genes that may reflect differences in Pre-DM compared with T2 DM. In addition, there were Cp G hypomethylation changes associated with a number of genes that may be associated with development of complications of diabetes, such as nephropathy. These hypomethylation changes were observed in all of the subjects.CONCLUSION: These data suggest that some epigenomic changes that may be involved in the progression of diabetes and/or the development of complications may be apparent at the Pre-DM state or during the transition to diabetes. Hypomethylation of a number of genes related to kidney function may be an early marker for developing diabetic nephropathy.	Thomas A Vander Jagt Monica H Neugebauer Marilee Morgan Donald W Bowden Vallabh O Shah	2015	World Journal of Diabetes2015，6，9：	5
2	The isothermal austenite-ferrite transformation in some deformed vanadium steels显示文摘	M J Crooks A J Garratt-Reed J B Vander Sande W S Owen	1982	Metallurgical Transactions A1982，，8：	2
3	Evaluation of the biocompatibility of a chitosan scaffold in mice显示文摘	vander Vord P J Matthew H W DeSilva S P et aI	2002	Biomed Mater Res2002，59，3：	1
4	A stable model of cirrhotic portal hypertension in the rat: thioacetamide revisited 显示文摘	Laleman W Vander Elst I Zeegers M	2006	Eur J Clin Invest2006，36，4：	1
5	Interaction between local and overall buckling of the stiffened compression panels显示文摘	Koiter W T Vander Neut	1980	Thin Walled Structures1980，，：	1
6	Modulation of E2F complexes during G to S phase transition in human p rimary Blymphocytes显示文摘	Vander Sman J Thomas N S Lam E W	1999	J Biol Chem1999，274，17：	1
7	Mossbauer study of several ferromagnetic spinals 显示文摘	Sawatzky G A Vander W F Morrish A H	1969	Phys Rev1969，187，：	1
8	Towards consensus in operational definitions in functionalcapacity evolution:a Delphi Survey显示文摘	Soer R Vander Sehans C P Groothoff J W	2008	J OccupRehabi2008，18，2：	1
9	Heat shock- induced cardioprotection activates cytoskeletal-based cell survival pathways 显示文摘	WEI H CAMPBELL W VANDER HEIDE R S	2006	Am J Physiol Heart Circ Physiol2006，291，2：	1
10	Isolation of a capsid protein of bluetongue virus that induces a protective immune re- sponse in sheep显示文摘	Huismans H Vander W N T Cloete M	1987	Virology1987，157，：	1
11	The Influence of Cooling Rate on the Specific Volume ofIsotactic Poly(propylene) at Elevated Pressures 显示文摘	Vander Beek M H E Peters G W M Meijer H E H	2005	Mac-romolecular Materials and Engineering2005，290，：	1
12	Heat shock proteins induce T-cell regulation of chronic inflammation显示文摘	Van Eden W vander Zee R Prakken B	2005	Nat Rev immunol2005，5，4：	1
13	HMO-CoA reductase inhibitors and the risk of vertebral fracture显示文摘	SOHOOFS M W SCURKENBOOM M O VANDER K M	2004	Bone Miner Res2004，19，9：	1
14	The influence of work characteristics on the need for recovery and experienced health:a study on coach drivers显示文摘	SLUITER J K VANDER BEEK A J FRINGS-DRESEN M H W	1999	Ergonomics1999，42，4：	1
15	Growth factor receptor profile of CD34^+ cells in AML and B-lineage ALL and in their normal bone marrow显示文摘	DE WAELE M RENMANS W VANDER GUCHT K	2001	Eur J Haematol2001，66，：	1
16	Determination of alkylphenol ethoxylates in industrial and environmental samples显示文摘	Voogt P D Beer K D Vander W F 1997	1997	Tr Anal Chem1997，16，：	1
17	Hepatitis E: an overview 显示文摘	Worm H C Vander Poel W H M Brandster G	2002	Mierobes Infect2002，4，：	1
18	Epidemiology and risk factors of dementia 显示文摘	VANDER FLIER W M SCHELTENS P	2005	J Neurosurg Psychiatry2005，76，1：	1
19	Carbon allocation to shot and roots in relation to nitrogen supply is mediated by cytokinins and sucrose : Opinion 显示文摘	Adrie Vander Weft Oscar W Nagel	1996	Plant and Soil1996，185，：	1
20	Acute exacerbations of chro- nic obstructive pulmonary disease and the effect of existing psychiatric eomorbidity on subsequent mortality 显示文摘	Abrams TE Vaughan-SM Vander W	2011	Psychosomatics2011，52，5：	1

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