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| 1 | Imaging evaluation of hemoptysis in children显示文摘Hemoptysis is an uncommon but distressing symptom in children. It poses a diagnostic challenge as it is difficult to elicit a clear history and perform thorough physical examination in a child. The cause of hemoptysis in children can vary with the child's age. It can range from infection, milk protein allergy and congenital heart disease in early childhood, to vasculitis, bronchial tumor and bronchiectasis in older children. Acute lower respiratory tract infections are the most common cause of pediatric hemoptysis. The objective of imaging is to identify the source of bleeding, underlying primary cause, and serve as a roadmap for invasive procedures. Hemoptysis originates primarily from the bronchial arteries. The imaging modalities available for the diagnostic evaluation of hemoptysis include chest radiography, multi-detector computed tomography(MDCT), magnetic resonance imaging(MRI) and catheter angiography. Chest radiography is the initial screening tool. It can help in lateralizing the bleeding with high degree of accuracy and can detect several parenchymal and pleural abnormalities. However, it may be normal in up to 30% cases. MDCT is a rapid, non-invasive multiplanar imaging modality. It aids in evaluation of hemoptysis by depiction of underlying disease, assessment of consequences of hemorrhage and provides panoramic view of the thoracic vasculature. The various structures which need to be assessed carefully include the pulmonary parenchyma, tracheobronchial tree, pulmonary arteries, bronchial arteries and non-bronchial systemic arteries. Since the use of MDCT entails radiation exposure, optimal low dose protocols should be used so as to keep radiation dose as low as reasonably achievable. MRI and catheter angiography have limited application. | Divya Singh Ashu Seith Bhalla Prasad Thotton Veedu Arundeep Arora | 2013 | World Journal of Clinical Pediatrics2013，2，4： | 12 |
| 2 | Pediatric vs adult pulmonary tuberculosis:A retrospective computed tomography study显示文摘AIM: To compare the manifestations of chest tuberculosis(TB) in pediatric and adult patients based on contrast enhanced computed tomography of chest.METHODS: This was a retrospective study consisting of 152 patients of chest TB including 48 children and 104 adults who had undergone contrast enhanced computed tomography of chest prior to treatment. The patterns and severity of parenchymal, mediastinal and pleural manifestations were analyzed and compared among different age groups.RESULTS: Parenchymal changes observed include consolidation, air space nodules, miliary TB, cavitation, bronchiectasis and fibrosis and these were noted in 60% of children, 71% of adolescents and 76.9% of adults. These changes were more common in right upper lobe in all age groups. There was no significant difference in the frequency of these changes(except nodules) in different age groups. Centrilobular nodules were seen less commonly in children less than 10 years(P = 0.028). Pleural effusion was noted in 28(18.42%) patients and pericardial effusion in 8(5.3%) patients. No significant difference in the serosal involvement is seen among children and adults. Mediastinal adenopathy was seen 70% of children, 76.3% adolescents and 76.9% of adults and paratracheal nodes were seen most frequently. Nodes had similar features(except matting) among all age groups. Matting of nodes was seen more commonly in children(P = 0.014). CONCLUSION: Pediatric chest tuberculosis can have severe parenchymal lesions and nodal involvement similar to adults. The destructive lung changes observed in children needs immediate attention in view of the longer life span they have and hence in formulating optimal treatment strategies. | Prasad Thotton Veedu Ashu Seith Bhalla Sreenivas Vishnubhatla Sushil Kumar Kabra Arundeep Arora Divya Singh Arun Kumar Gupta | 2013 | World Journal of Clinical Pediatrics2013，2，4： | 2 |
| 3 | Enzymatic polymerization involveing'2'-amino-LNA nucleotides 显示文摘 | Joharmsen MW Veedu RN Madsen as | 2012 | Bioorg Med Chem Let-t2012，22，10： | 1 |
| 4 | On cubic Hermite coalescence hidden variable fractal interpolation functions显示文摘Hermite interpolation is a very important tool in approximation theory and numerical analysis, and provides a popular method for modeling in the area of computer aided geometric design. However, the classical Hermite interpolant is unique for a prescribed data set,and hence lacks freedom for the choice of an interpolating curve, which is a crucial requirement in design environment. Even though there is a rather well developed fractal theory for Hermite interpolation that offers a large flexibility in the choice of interpolants, it also has the shortcoming that the functions that can be well approximated are highly restricted to the class of self-affine functions. The primary objective of this paper is to suggest a C1-cubic Hermite interpolation scheme using a fractal methodology, namely, the coalescence hidden variable fractal interpolation, which works equally well for the approximation of a self-affine and non-self-affine data generating functions. The uniform error bound for the proposed fractal interpolant is established to demonstrate that the convergence properties are similar to that of the classical Hermite interpolant. For the Hermite interpolation problem, if the derivative values are not actually prescribed at the knots, then we assign these values so that the interpolant gains global C2-continuity. Consequently, the procedure culminates with the construction of cubic spline coalescence hidden variable fractal interpolants. Thus, the present article also provides an alternative to the construction of cubic spline coalescence hidden variable fractal interpolation functions through moments proposed by Chand and Kapoor [Fractals, 15(1)(2007), pp. 41-53]. | Puthan Veedu Viswanathan Arya Kumar Bedabrata Chand | 2015 | Applied Mathematics(A Journal of Chinese Universities)2015，30，1： | 1 |
| 5 | Multifunctional brushes made from carbon nanotubes显示文摘 | Cao A Y Veedu V P Li X S | 2005 | Nature Materials2005，4，7： | 1 |
| 6 | Type 2diabetes mellitus:limitations of conventional therapies and intervention with nucleic acid-based therapeutics显示文摘 | Kokil GR Veedu RN Ramm GA | 2015 | Chem Rev2015，115，11： | 1 |
| 7 | Multifunctional composites using reinforced laminae with carbon-nanotube forests显示文摘 | Veedu V P Cao A Y Li X S | 2006 | Nature Materials2006，5，6： | 1 |
| 8 | G-rich VEGF aptamer with locked and unlocked nucleic acid modifications ex- hibits a unique G-quadruplex fold显示文摘 | MARUSIC M VEEDU RN WENGEL J | 2013 | Nucleic Acids Res2013，41，20： | 1 |
| 9 | Multifunctional composites using reinforced laminae with carbon-nanotube forests显示文摘 | Veedu V P Cao A Y Li X S | 2006 | Nature Materials2006，5，： | 1 |
| 10 | Multifunctional composites using reinforced lami-nae with carbonnanotube forests显示文摘 | Veedu VP Cao AY Li XS Ma KG Soldano C Kar S | | 0，，07： | 1 |
| 11 | Locked nucleic acids: promising nucleic acid analogs for therapeutic applications显示文摘 | Veedu RN Wengel J | 2010 | Chemistry biodi-versity2010，7，3： | 1 |
| 12 | Multifunctional com- posites using reinforced laminae with carbon-nanotube fo- rests显示文摘 | Veedu V P Cao A Y Li X S | 2006 | Nat Mater2006，5，： | 1 |
| 13 | Multifunctional composites using reinforced laminae with carbon nanotube forests 显示文摘 | VEEDU V P CAO An-yuan LI Xue-song | 2006 | Nature Materials2006，5，6： | 1 |
| 14 | Targeted multimodal liposomes for nano-delivery and imaging: an avenger for drug resistance and cancer显示文摘 | Gurudevan S Kanwar RK Veedu RN | 2013 | CUIT Gene Ther2013，13，5： | 1 |
| 15 | Multifunctional composites using reinforced lamine with carbon-nano- tubes forests显示文摘 | Veedu V P Cao A Y Li X S | 2006 | Nature Material2006，，5： | 1 |
| 16 | Multifunctional brushes made from carbon nanotubes 显示文摘 | CAO A VEEDU V P LI X | 2005 | Nature Materials2005，4，7： | 1 |
| 17 | Multifunctional composites using reinforced laminae with carbon-nanotube forests 显示文摘 | VEEDU V P CAO A LI X | 2006 | Nature materials2006，5，6： | 1 |
| 18 | Multifunctional composites using reinforced laminae with carbon nanotube forests显示文摘 | Veedu V P Cao A Li X | 2006 | Nature materials2006，5，： | 1 |
| 19 | Role of ictal baseline shifts and ictal high-frequency oscillations in stereo- electroencephalography analysis of mesial temporal lobe seizures 显示文摘 | Wu S Kunhi Veedu HP Lbatoo SD | 2014 | Epilepsia2014，55，5： | 1 |
| 20 | Multifunctional composites using reinforced laminae with carbon- nanotube forests 显示文摘 | VEEDU VP CAO AY LI XS | 2006 | Nat Mater2006，5，6： | 1 |
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