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| 1 | Biosynthesis of silver nanoparticles by using mangrove plant extract and their potential mosquito larvicidal property显示文摘Objective:To identify the larvicidal activities of silver nano particles synthesised with Rhizophora mucronata(R.mucronata) leaf extract against the larvae of Aedes aegypti(Ae.aegypti) and Culex quinquefasciatus(Cx.quinquefasciatus).Methods:In vitro larvicidal activities such as LC50 and LC90 were assessed for the Ae.aegypti and Cx.quinquefasciatus larval species.Further, characterisation such as UV,XRD,FTIR and AFM analysis were carried out for the synthesised silver nano particles.Results:The LC50 value of the synthesised silver nano particle was identified as 0.585 and 0.891 mgg/L for Ae.aegypti and Cx.quinquefasciatus larvae respectively. Further,the LG90 values are also identified as 2.615 and 6.291 mg/L for Ae.aegypti and Cx. quinquefasciatus species respectively.The synthesised silver nanoparticles have maximum absorption at 420 nm with the average size of 60-95 nm.The XRD data showed 20 intense values with various degrees such as 37.10°,47.66°,63.97°and 70.01°.The FTIR data showed prominent peaks in(3 426.89,2 925.49,2 869.56,2 346.95,1 631.49,1 031.73,669.18 and 455.12) different ranges.Conclusions:The biosynthesis of silver nanoparticles with leaf aqueous extract of R. mucronata provides potential source for the larvicidal activity against mosquito borne diseases. | M Gnanadesigan M Anand S Ravikumar M Maruthupandy V Vijayakumar S Selvam M Dhineshkumar AK Kumaraguru | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，10： | 4 |
| 2 | And-hyperglycemic activity of leaves extract of Hyptis suavcolens L.Poit in streptozotocin induced diabetic rats显示文摘Objective:To evaluate the antihyperglycemic activity of leaves of Hyptis suaveolens using streptozotocin model.Mothods:Hyptis suaveolens extract(HSE) 250 and 500 mg/kg body weight was administered orally to streptozotocin induced diabetes,once daily for 21 days.Results:A significant reduction in blood glucose was observed in diabetic animals treated with HSE at different doses when compared with diabetic rats.Levels of triglyceride,total cholesterol,low density lipoprolein.very low density lipoprotein were decreased while administering HSE at different doses,compared with their control values in diabetic animals.Conclusions:Our results show that HSE possesses significant antihyperglycemic activity which might be attributed to stimulating effects on glucose utilization and antioxidant enzyme. | Shanti Bhushan Mishra Amita Verma Alok Mukerjee Vijayakumar M | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 4 |
| 3 | Phytochemical analysis and in vitro antimicrobial activity of Illicium griffithii Hook. f. & Thoms extracts显示文摘 | A Vijayakumar V Duraipandiyan B Jeyaraj P Agastian M Karunai Raj S Ignacimuthu | 2012 | Asian Pacific Journal of Tropical Disease2012，，3： | 4 |
| 4 | Evaluation of chemopreventive effect of Fumaria indica against N-nitrosodiethylamine and CCl_4-induced hepatocellular carcinoma in Wistar rats显示文摘Objective:To investigation the chemopreventive potential of Fumaria indica(F.indica) extract(FIE) on N-nitrosodiethylamine and CCl4-induced hepatocarcinogenesis in Wislar rats.Methods:The experimental animals were divided into six groups(n=6).Hepatocellular carcinoma was induced by single intraperitoneal injection of N-nitrosodiethylamine(NDEA) in normal saline at a dose of 200 mg/kg body weight followed by weekly subcutaneous injections of CCl4(3 mL/kg/week) for 6 weeks,as the promoter of carcinogenic effect.After administration of the carcinogen,200 and 400 mg/kg of FIE were administered orally once a day throughout the study.At the end of 20 weeks,the body weight,liver weight and relative liver weight were measured.The percentage of nodule incidence and liver cancer markers such as aspartate transaminase(AST),alanine transaminase(ALT),alkaline phosphatase(ALP),γ-glutamyl transferase(γ-GT),total bilirubin level(TBL),α-feto protein(AFP) and carcinoembryonic antigen were estimated along with histopathological investigation in experimental groups of rats. Results:Obtained results demonstrated that the cotreatment with FIE significantly prevented the decrease of the body weight and also increased in relative liver weight caused by NDEA. The treatment with FIE significantly reduced the nodule incidence and nodule multiplicity in the rats after NDEA administration.The levels of liver cancer markers such as AST,ALT,ALP,γ-glutamyl transferase,TBL,AFP and carcinoembryonic antigen were substantially increased by NDEA treatment.However,FIE treatment significantly reduced the liver injury and restored the entire liver cancer markers.Histological observations of liver tissues too correlated with the biochemical observations.Conclusions:These finding powerfully supports that F.indica exert chemopreventive effect by suppressing the tumor burden and restoring the activities of hepatic cancer marker enzymes on NDEA and CCl4-induced hepatocarcinogenesis in Wistar rats. | Talib Hussain Hefazat H Siddiqui Sheeba Fareed M Vijayakumar Chandana V Rao | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，8： | 3 |
| 5 | Effect of quercetin, flavonoids and alpha-tocopherol, an antioxidant vitamin on experimental reflux oesophagitis in rats显示文摘 | Rao CV Vijayakumar M | 2008 | Eur J Pharmacol2008，589，13： | 1 |
| 6 | Self-propag atinghigh-temperature synthesis 显示文摘 | Surbrahmanyam J Vijayakumar M | 1992 | Mater Sci1992，27，23： | 1 |
| 7 | Copolymers of poly(lactic acid) and D-alpha-tocopheryl polyethylene glycol 1000 succinate-based nanomedicines: Versatile multifunctional platforms for cancer diagnosis and therapy显示文摘 | VIJAYAKUMAR M R MUTHU M S SINGH S | 2013 | Expert Opin Drug Deliv2013，10，4： | 1 |
| 8 | Towards understanding the poor thermal stability of V5+electrolyte solution in vanadium redox flow batteries显示文摘 | Vijayakumar M Li L Y Graff G | 2011 | Journal of Power Sources2011，196，7： | 1 |
| 9 | Selective method for the complexometric determination of copper in alloys and ores 显示文摘 | Rukmani N Desikan M Vijayakumar M | 1985 | Analyst1985，110，11： | 1 |
| 10 | In vitro and in vivo antioxidant properties and DNA damage protective activity of green fruit of Ficus glomerata 显示文摘 | VERMA A R VIJAYAKUMAR M V RAO C V | 2010 | Food Chem Toxicol2010，48，2： | 1 |
| 11 | Evaluation of the use of DMSA in culture positive UTI and culture negative acute pyelonephritis显示文摘 | Vijayakumar M Sankar J | 2006 | Indian Pediatr2006，43，： | 1 |
| 12 | Combustion- assisted Synthesis of Ti-TiB-TiC & Ti-TiB Composite via the Casting Route 显示文摘 | Ranganath S Vijayakumar M Subrahmanyam J | 1992 | Materials Science and Engineering A1992，149，： | 1 |
| 13 | Molecular diversity and multilocus organization of the parental lines used in the International Rice Molecular Breeding Program显示文摘 | Yu S B Xu W J Vijayakumar C H M | 2003 | Theor Appl Genet2003，108，： | 1 |
| 14 | Photoluminescence from RF sputtered SiCBN thin films 显示文摘 | Vijayakumar A Warren A P Todi R M | 2009 | Journal of Materials Science : Materials in Electronics2009，20，2： | 1 |
| 15 | Action of Asparagus racemosus against streptozotocin-induced oxidative stress显示文摘 | Govindarajan R Vijayakumar M Rao CV Kumar V Rawat AKS Pushpangadan P | 2004 | Nat Prod Sci2004，10，4： | 1 |
| 16 | Effect of Fluorine Doping on Structural,Electrical and Optical Properties of Zn O Thin Films显示文摘 | Ratheesh Kumar P M Sudha Kartha C Vijayakumar K P | 2005 | Material Science and Engineering B2005，117，2： | 1 |
| 17 | Influence of triple-lu- men central venous catheters coated with chlorhexidine and silver sulfadiazine on the incidence of catheter-related bacteremia 显示文摘 | Heard SO Wagle M Vijayakumar E | 2008 | Arch Intern Med2008，158，1： | 1 |
| 18 | Lithium diffu- sion in Li4Ti5O12 at high temperatures 显示文摘 | VIJAYAKUMAR M KERISIT S ROSSO K M | 2011 | J Power Sources2011，196，： | 1 |
| 19 | Evaluation and management of hypertension显示文摘 | Bagg AA Jain R Vijayakumar M | | 0，，02： | 1 |
| 20 | Natural history of zebrafish(Danio rerio)in India显示文摘 | ARIMACHALAM M RAJA M VIJAYAKUMAR C | 2013 | Zebrafish2013，10，1： | 1 |
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