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| 1 | DYNAMICS MODEL AND SIMULATION OF FLAT VALVE SYSTEM OF INTERNAL COMBUSTION WATER PUMP显示文摘The dynamics differential equations are constructed, and the initial conditions are alsogiven. Simulation shows the following conclusions: The water pressure in cylinder has great instanta-neous pulsation and phase step when outlet valve or inlet valve opens, but is more gently in othertime; The volume efficiency is influenced by the output pressure slightly, and decreases as the work-ing rotational speed increases; When the inherent frequency of the valves is integer multiple of theworking frequency, the volume efficiency of system will decrease evidently. | Zhang Hongxin Zhang Tiezhu Wang Yushun Zhao Hong Huo Wei | 2005 | Chinese Journal of Mechanical Engineering2005，18，3： | 39 |
| 2 | MicroRNA-548 down-regulates host antiviral response via direct targeting of IFN-λ1显示文摘Interferon(IFN)-mediated pathways are a crucial part of the cellular response against viral infection.Type III IFNs,which include IFN-λ1,2 and 3,mediate antiviral responses similar to Type I IFNs via a distinct receptor complex.IFN-λ1 is more effective than the other two members.Transcription of IFN-λ1 requires activation of IRF3/7 and nuclear factor-kappa B(NF-κB),similar to the transcriptional mechanism of Type I IFNs.Using reporter assays,we discovered that viral infection in-duced both IFN-λ1 promoter activity and that of the 3′-untranslated region(UTR),indicating that IFN-λ1 expression is also regulated at the post-transcriptional level.After analysis with microRNA(miRNA)prediction programs and 3′UTR targeting site assays,the miR-NA-548 family,including miR-548b-5p,miR-548c-5p,miR-548i,miR-548j,and miR-548n,was identified to target the 3′UTR of IFN-λ1.Further study demonstrated that miRNA-548 mimics down-regulated the expression of IFN-λ1.In contrast,their inhibitors,the complemen-tary RNAs,enhanced the expression of IFN-λ1 and IFN-stimulated genes.Furthermore,miRNA-548 mimics promoted infection by enterovirus-71(EV71)and ve-sicular stomatitis virus(VSV),whereas their inhibitors significantly suppressed the replication of EV71 and VSV.Endogenous miRNA-548 levels were suppressed during viral infection.In conclusion,our results sug-gest that miRNA-548 regulates host antiviral response via direct targeting of IFN-λ1,which may offer a poten-tial candidate for antiviral therapy. | Yongkui Li Jiajia Xie Xiupeng Xu Jun Wang Fang Ao Yushun Wan Ying Zhu | 2013 | Protein & Cell2013，4，2： | 22 |
| 3 | The development of China's Yangtze River Economic Belt:how to make it in a green way?显示文摘The Yangtze River is one of the largest and longest rivers in Asia.The river originates in the Tibet-Qinghai Plateau(headwater reach),passes through the mountainous provinces of Sichuan,Yunnan and Chongqing(upper reach),flows into the Central Plain(middle reach)and Lower Plain(lower reach),and finally empties into the East China Sea in Shanghai(estuary).The Yangtze River Economic Belt(YREB;Fig.1)has a surface area of 2.1 | Yushun Chen Shuanghu Zhang Desheng Huang Bai-Lian Li Junguo Liu Wenjin Liu Jing Ma Fang Wang Yong Wang Shengjun Wu Yegang Wu Jinyue Yan Chuanbo Guo Wei Xin Hao Wang | 2017 | Science Bulletin2017，62，9： | 20 |
| 4 | Concatenating construction of the multisymplectic schemes for 2+1-dimensional sine-Gordon equation显示文摘In this paper, taking the 2+1-dimensional sine-Gordon equation as an example, we present the concatenating method to construct the multisymplectic schemes. The method is to discretizee independently the PDEs in different directions with symplectic schemes, so that the multisymplectic schemes can be constructed by concatenating those symplectic schemes. By this method, we can construct multisymplectic schemes, including some widely used schemes with an accuracy of any order. The numerical simulation on the collisions of solitons are also proposed to illustrate the efficiency of the multisymplectic schemes. | WANG Yushun, WANG Bin & QIN MengzhaoLASG, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China School of Mathematics and Computer Science, Nanjing Normal University, Nanjing 210097, China School of Mathematics and System Science, Chinese Academy of Sciences, Beijing 100080, China | 2004 | Science China Mathematics2004，47，1： | 17 |
| 5 | Comparative study of minimally invasive versus open esophagectomy for esophageal cancer in a single cancer center显示文摘 | Mu Juwei Yuan Zuyang Zhang Baihua Li Ning Lyu Fang Mao Yousheng Xue Qi Gao Shugeng Zhao Jun Wang Dali Li Zhishan Gao Yushun Zhang Liangze Huang Jinfeng Shao Kang Feng Feiyue Zhao Liang Li Jian Cheng Guiyu Sun Kelin He Jie | 2014 | Chinese Medical Journal2014，，4： | 13 |
| 6 | Local structure-preserving algorithms for partial differential equations显示文摘In this paper, we discuss the concept of local structure-preserving algorithms (SPAs) for partial differential equations, which are the natural generalization of the corresponding global SPAs. Local SPAs for the problems with proper boundary conditions are global SPAs, but the inverse is not necessarily valid. The concept of the local SPAs can explain the difference between different SPAs and provide a basic theory for analyzing and constructing high performance SPAs. Furthermore, it enlarges the applicable scopes of SPAs. We also discuss the application and the construction of local SPAs and derive several new SPAs for the nonlinear Klein-Gordon equation. | WANG YuShun WANG Bin QIN MengZhao | 2008 | Science China Mathematics2008，51，11： | 10 |
| 7 | Inducible Rubicon facilitates viral replication by antagonizing interferon production显示文摘The RUN domain Beclin-1-interacting cysteine-rich-containing(Rubicon)protein is involved in the maturation step of autophagy and the endocytic pathway as a Beclin-1-binding partner,but little is known regarding the role of Rubicon during viral infection.Here,we performed functional studies of the identified target in interferon(IFN)signaling pathways associated with Rubicon to elucidate the mechanisms of viral resistance to IFN.The Rubicon protein levels were elevated in peripheral blood mononuclear cells,sera and liver tissues from patients with hepatitis B virus(HBV)infection relative to those in healthy individuals.Assays of the overexpression and knockdown of Rubicon showed that Rubicon significantly promoted HBV replication.In addition,Rubicon knockdown resulted in the inhibition of enterovirus 71,influenza A virus and vesicular stomatitis virus.The expression o0f Rubicon led to the suppression of virus-induced type-I interferon(IFN-αand IFN-β)and type-III interferon(IFN-λ1).Translocation of activated IRF3 and IRF7 from the cytoplasm to the nucleus was involved in this process,and the NF-κB essential modulator(NEMO),a key factor in the IFN pathway,was the target with which Rubicon interacted.Our results reveal a previously unrecognized function of Rubicon as a virus-induced protein that binds to NEMO,leading to the inhibition of type-I interferon production.Rubicon thus functions as an important negative regulator of the innate immune response,enhances viral replication and may play a role in viral immune evasion. | Yushun Wan Wei Cao Tao Han Sheng Ren Jian Feng TieLong Chen Jun Wang Ruth Broering Mengji Lu Ying Zhu | 2017 | Cellular & Molecular Immunology2017，14，7： | 4 |
| 8 | Effects of 4DVAR with multifold observed data on the typhoon track forecast显示文摘Effects of 4-dimension variational data assimi-lation (4DVAR) with multifold observed data on the typhoontrack forecast are studied, by using the MM5V3 model, theRTTOVS-5 model and their adjoint models. The data usedfor assimilation include large-scale background fields data,bogus data, cloud-derived wind data, satellite inverse data,and high resolution infrared radiation sounder data (HIRS).There are 5 typhoon cases are used to perform the numericalexperiments and assimilation experiments. The numericalresults show that with 4DVAR the initial fields can be greatlyimproved and the initial typhoon structure can be clearlydescribed. | WANG Yunfeng, WANG Bin, MA GANG & WANG Yushun 1. LASG, Institute of Atmospheric Physics, Chinese Academy of Sciences. Beijing 100029, China: 2. National Satellite Meteorological Center, Beijing 100081. China | 2003 | Chinese Science Bulletin2003，48，S2： | 3 |
| 9 | LOCAL STRUCTURE-PRESERVING ALGORITHMS FOR THE KDV EQUATION显示文摘在这份报纸,基于并置的方法,我们在场为 Korteweg-de Vries (KdV ) 方程构造一系列本地保存结构的算法的一个统一框架包括八个 multi-symplectic 算法,八个本地保存精力的算法和八个本地保存动量的算法。在这些算法之中,当大多数是新的时,一些被讨论了并且广泛地使用了。这些建议算法的突出的优点是他们确切在任何时间空间区域保存本地结构。因此,本地保存结构的算法在边界条件上克服全球保存结构的算法的限制。数字实验被进行显示出建议方法的表演。而且,统一框架能容易被用于许多另外的方程。 | Jialing Wang Yushun Wang | 2017 | Journal of Computational Mathematics2017，35，3： | 2 |
| 10 | Sorption and desorption of 1,4-dichlorobenzene on peat显示文摘Sorption and desorption of 1,4-dichlorobenzene (DCB) on peat (>92% organic matter) display large-scale hysteresis and nonlinearity. The magnitude of desorption hysteresis decreases in the order: untreated Pahokee peat (P)> acid treated peat (FP)> humin (TP). The desorption percentages are lower than 28% of the sorbed 1, 4-DCB after desorbing for 6 days. The sorption and desorption isotherms are well fitted to Freundlich equation, whose parameter 1/n ranges from 0.055 to 0.527. Moreover, the parameter 1/n of the desorption isotherm is significantly lower than that of the sorption isotherm, but the parameter logK increases on contrary to 1/n. The desorption isotherms are very well fitted to Langmuir equation, whose Qm decreases in the order: TP>FP> P. The apparent partition coefficients (Kp) increase with increasing sorption time or decreasing aqueous equilibrium concentration of DCB. And Kp of P is significantly higher than that of FP or TP. | RAN Yong LIN Zheng WANG Xili MIN Yushun SHENG Guoying FU Jiamo | 2000 | Chinese Science Bulletin2000，45，S1： | 1 |
| 11 | A SIXTH ORDER AVERAGED VECTOR FIELD METHOD显示文摘在这份报纸,基于生根的树和 B 系列的理论,我们为顺序 = 的树建议替换法律的具体公式 5。在新替换法律的帮助下,我们导出扩大平均向量地(AVF ) 方法让一般 Hamiltonian 系统更高订的一个 B 系列综合者。新综合者结果是六的顺序并且确切为 Hamiltonian 系统保存精力。数字实验被介绍表明精确性和第六个顺序 AVF 方法的保存精力的性质。[从作者抽象] | Haochen Li Yushun Wang Mengzhao Qin | 2016 | Journal of Computational Mathematics2016，34，5： | 1 |
| 12 | HIGH ORDER COMPACT MULTISYMPLECTIC SCHEME FOR COUPLED NONLINEAR SCHRODINGER-KDV EQUATIONS显示文摘 | Lan Wang Yushun Wang | 2018 | Journal of Computational Mathematics2018，36，4： | 1 |
| 13 | Effect of selective uterine artery embolization on symptomatic uterine fibroids显示文摘Objective: To evaluate the outcomes of selective uterine artery embolization (SUAE) in treatment of symptomatic uterine fibroids using Color Doppler ultrasonography (CDUS). Methods: As the procedure SUAE for fibroids, prospective data of the initial 65 consecutive women treated from March 2007 to September 2009 were collected. The follow-up period from 1 week to 30 months, using questionnaires, we investigated the fibroid-related physical and psychological symptoms, and the cumulative rates of symptom control, gynecologic interventions, and complications. The volumes of uterine and uterine fibroids were calculated by CDUS pre- and post-SUAE for 6 months. And we tested the levels of internal hormone including FSH, LH and E2 before and after SUAE for 3, 6 months. Results: SUAE was performed successfully in all patients. There was no peri-operative morbidity in all procedures. Compared with pre-SUAE volumes of uterine [(322±112) cm3] and uterine fibroids [(125±46) cm3], their volumes in post-SUAE were (144±72) cm3 and (51±11) cm3 (P<0.01), and reduction rate was 58% and 61%, respectively. At 3, 6 months after SUAE, levels of FSH, LH, and E2 were not decreased than that of in pre-SUAE (P>0.05). After SUAE for 24 months, the fibroids related physical and psychological symptoms such as bleeding, pain and quality of life were significantly improved (P<0.01). 90.8% (59/65) women had resolution of symptoms and no significant post-procedural symptoms. Parts of patients discharge necrotic fibroids. 86% (34/40) complications were minor, requiring no therapy. 9.2% (6/65) had significant post-procedural symptoms, requiring therapy in hospital or out-patient department. Conclusion: SUAE contributes to a long-term significant improvement of all investigated uterine fibroid-related symptoms and markedly improves women's health-related quality of life. SUAE that no impair on changes of internal hormone, under suitable conditions, represents an attractive alternative to hysterectomy for the treatment of symptomatic fibroids and is a minimally invasive, new method of good clinical prognosis. CDUS is an effective to investigate the outcome of SUAE. | Feng Jun Liu Yamin Zhang Yushun Wang Lijuan Wang Xingye Qin Hao Gou Wenli | 2009 | Journal of Medical Colleges of PLA(China)2009，24，6： | 1 |
| 14 | Multisymplectic five-point scheme for the nonlinear wave equation显示文摘In this paper, we introduce the multisymplecticstructure of the nonlinear wave equation, and prove that theclassical five-point scheme for the equation is multisymplec-tic. Numerical simulations of this multisymplectic scheme onhighly oscillatory waves of the nonlinear Klein-Gordonequation and the collisions between kink and anti-kink soli-tons of the sine-Gordon equation are also provided. The mul-tisymplectic schemes do not need to discrete PDEs in thespace first as the symplectic schemes do and preserve notonly the geometric structure of the PDEs accurately, but alsotheir first integrals approximately such as the energy, themomentum and so on. Thus the multisymplectic schemeshave better numerical stability and long-time numerical be-havior than the energy-conserving scheme and the symplec-tic scheme. | WANG Yushun~(1,2), WANG Bin~1, YANG Hongwei~1 & WANG Yunfeng~1 1. LASG, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029. China 2. Permanent address: School of Mathematics and Computer Science, Nanjing Normal University, Nanjing 210097. China | 2003 | Chinese Science Bulletin2003，48，S2： | 1 |
| 15 | DNA hypermethylation of microRNA-34b/c has prognostic value for stage I non- small cell lung cancer 显示文摘 | Zhen Wang Zhaoli Chen Yushun Gao | 2011 | Cancer Biology & Therapy2011，11，5： | 1 |
| 16 | Characteristics and possible origins of atmospheric monoterpenes from nonliving plants in Guangzhou显示文摘Monoterpenes in ambient air were determined in various sites in Guangzhou, and it was revealed that monoterpene concentrations in some special sites, like landfills, were even higher than those in locations with much more vegetation. On the average, monoterpene contents in samples from streets and highways were 1.9 μg/m3; from gardens, plantations and wooded lands, 2.2 μg/m3; from farmlands, 1.5 μg/m3; but from landfills, 4.1 μg/m3. So other sources like landfills, apart from living plants, might also contribute to the biogenic non-methane hydrocarbons (NMHCs) in the atmospheric environment. On the other hand, the composition pattern of monoterpenes in air samples from landfills were obviously different compared with those from living plants, this might result from the different synthesis pathways of monoterpenes, the oxygen-depleted environment and the microbiogenic process might affect the synthesis in landfills. | Xinming Wang Guoying Sheng Jiamo Fu Yushun Min Ping’an Peng | 1999 | Chinese Science Bulletin1999，44，8： | 1 |
| 17 | 3D Printing of Nacre-Inspired Structures with Exceptional Mechanical and Flame-Retardant Properties显示文摘Flame-retardant and thermal management structures have attracted great attention duc to the requirement of high-temperature exposure in industrial,aerospace,and thermal power fields,but the development of protoctive fire-retardant structures with complex shapes to fit arbitrary surfaces is still challenging.Herein,we reported a rotation-blade casting-assisted 3D printing process to fabricate nacre-inspired structures with exceptional mechanical and flame-retardant properties,and the relatedi fundamental mechanisms are studied.3-(Trimethoxysilyl)propyl methacrylate(TMSPMA)modified boron nitride nanoplatelets(BNs)were aligned by rotation-blade casting during the 3D printing process to build the'hrick and mortar'architecture.The 3D printed structures are more lightweight,while having higher fracture toughness than the natural nacre,which is attributed to the crack deflection,aligned BN(a-BNs)bridging,and pull-outs reinforced structures by the covalent bonding between TMSPMA grafted a-BNs and polymer matrix.Thermal conductivity is enhanced by 25.5 times compared with pure polymer and 5.8 times of anisotropy due to the interconnection of a-BNs.3D printed heat-exchange structures with vertically aligned BNs in complex shapes were demonstrated for efficient thermal control of high-power light-emitting diocles.3D printed helmet and armor with a-BNs show exceptional mechanical and fire-retardant properties,demonstrating integrated mechanical and thermal protection. | Yang Yang Ziyu Wang Qingqing He Xiangjia Li Gengxi Lu Laiming Jjiang Yushun Zeng Brandon Bethers Jie Jin Shuang Lin Siqi Xiao Yizhen Zhu Xianke Wu Wenwu Xu Qiming Wang Yong Chen | 2022 | Research2022，，2： | 1 |
| 18 | Local structure-preserving al- gorithms for the 'good' Boussinesq equation 显示文摘 | Cai Jiaxiang Wang Yushun | 2013 | J Com- put Phys2013，239，1： | 1 |
| 19 | High-order multi-symplectic schemes for the nonlinear Klein-Gordon equation显示文摘 | Wang Yushun Wang Bin | 2005 | Appl Math Comput2005，166，3： | 1 |
| 20 | Arbitrarily High-Order Energy-Preserving Schemes for the Camassa-Holm Equation Based on the Quadratic Auxiliary Variable Approach显示文摘In this paper,we present a quadratic auxiliary variable(QAV)technique to develop a novel class of arbitrarily high-order energy-preserving algorithms for the Camassa-Holm equation.The QAV approach is first utilized to transform the original equation into a reformulated QAV system with a consistent initial condition.Then the reformulated QAV system is discretized by applying the Fourier pseudo-spectral method in space and the symplectic Runge-Kutta methods in time,which arrives at a class of fully discrete schemes.Under the consistent initial condition,they can be rewritten as a new fully discrete system by eliminating the introduced auxiliary variable,which is rigorously proved to be energy-preserving and symmetric.Ample numerical experiments are conducted to confirm the expected order of accuracy,conservative property and efficiency of the proposed methods.The presented numerical strategy makes it possible to directly apply a special class of Runge-Kutta methods to develop energy-preserving algorithms for a general conservative system with any polynomial energy. | Yuezheng Gong Qi Hong Chunwu Wang Yushun Wang | 2023 | Advances in Applied Mathematics and Mechanics2023，15，5： | 0 |
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