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| 1 | Progress in additive manufacturing on new materials: A review显示文摘Recent efforts and advances in additive manufacturing(AM) on different types of new materials are presented and reviewed. Special attention is paid to the material design of cladding layers, the choice of feedstock materials, the metallurgical behavior and synthesis principle during the AM process, and the resulted microstructures and properties, as well as the relationship between these factors. Thereafter,the trend of development in the future is forecasted, including: Effects of the particles size and size distribution of powders; Approaches for producing fine microstructures; Opportunities for creating new materials by AM; Wide applications in reconditioning of damaged components; Challenges for deep understanding and applications of the AMed new materials. The idea of 'Develop Materials' or 'Create Materials' by AM is highlighted, but a series of scientific, technological and engineering problems remain to be solved in future. | Neng Li Shuai Huang Guodong Zhang Renyao Qin Wei Liu Huaping Xiong Gongqi Shi Jon Blackburn | 2019 | Journal of Materials Science & Technology2019，35，2： | 47 |
| 2 | Congenital expression of mdr-1 gene in tissues of carcinoma and its relation with patho morphology and prognosis显示文摘NTRODUCTIONMultidrugresistance(MDR)ofmalignanttumorcelhasarousedwidespreadinterest.IthasbeenshownthatMDRispresentinmanymalign... | ZHANG Li Jian 1, CHEN Ke Neng 1, XU Guang Wei 1, XING Hai Ping 2 and SHI Xiao Tian 2 | 1999 | World Journal of Gastroenterology1999，5，1： | 15 |
| 3 | The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats显示文摘Objective To explore the Intervention effect of Rosiglitozone in ovarian fibrosis of PCOS rats.Methods 60 female SD rats were randomly divided into 3 groups:control group,model group and treatment group.The model and treatment groups were established by subcutaneous injection of DHEA,while the treatment group was given RGZ.The serum hormone values,pathohistology of ovarian structure of rats,ovarian ultrastructure and the expressions of TGF-β 1 and CTGF were detected.Results The PCOS model was established successfully.The expression intensity of TGF-β 1 and CTGF in Oocytes of the PCOS groups was 9.545±2.954 and 9.665±2.400,respectively and was significantly higher than that of the control group 6.636±2.264 and 7.036±2.133;after treatment with rosiglitazone,the expression was significantly decreased 6.980±2.421 and 6.642±2.721 as compared with that of the model group (P<0.05,P<0.001).The values in serum of the PCOS groups were 3.749±2.054 and 0.265±0.129,and 1.914±1.801 and 0.096±0.088 in the control group which had statistically significant difference (P<0.05,P<0.001).After treatment with rosiglitazone,the values were 2.3100±1.825 and 0.112±0.187 and were significantly different with those of the model group (P<0.05,P<0.001).Conclusion TGF-β 1 and CTGF play an important role in the development of ovary fibrosis in PCOS.However,RGZ may postpone the development of fibrosis by decreasing the levels of TGF-β 1 and CTGF. | MIAO Zhu Lin GUO Liang WANG Yong Xia CUI Rong YANG Ning HUANG Mi Qiong QIN Wei Bing CHEN Jin LI Hong Mei WANG Zi Neng WEI Xiang Cai | 2012 | Biomedical and Environmental Sciences2012，25，1： | 14 |
| 4 | Synthesis, mechanical investigation, and application of nitrogen and phosphorus co-doped carbon dots with a high photoluminescent quantum yield显示文摘有高 photoluminescent 量收益(PLQY ) 的做 Heteroatom 的碳点(CD ) 最近在化学传感器,光催化, bioimaging,和药交货中由于他们的应用吸引了注意。氮和磷在到在周期表的碳的靠近的最近并且是关键的在生物医学的成像的地里追踪元素。这二个元素改变 CD 的光、电子的性质并且帮助改进他们的 PLQY 的基本理解。这能也在 photoimaging 和 photothermal 治疗导致多功能的用法。然而,源于做 P 的 CD 的合成的大多数 PLQY 当前低于 50% 。这些 CD 在 bioimaging 和药交货的地里限制了实用性。在这研究,一个单个步的、高效率的热水的方法被使用综合氮和磷药的碳点((N, P ) 有有独立排放的多达 53.8% 的 PLQY 的 -CDs) 行为。而且, CD 在一个大 pH 范围上介绍了高 monodispersity,柔韧的刺激无关的光,和稳定性。分光镜的调查显示 PLQY (N, P ) CD 主要由于 P 的增加和氧化表面的钝化效果。优秀荧光性质(N, P ) CD 能被 Hg 2+ 离子有效地并且有选择地熄灭。如此的系统与一短反应时间在 0-900 nM 集中范围显示出线性回答,显示他们为化学和生物学的领域里的应用程序的潜力。 | Quan Xu Bofan Li Yingchun Ye Wei Cai Weijun Li Chuanyao Yang Yusheng Chen Meng Xu Neng Li Xusheng Zheng Jason Street Yan Luo Lulu Cai | 2018 | Nano Research2018，11，7： | 7 |
| 5 | Red/orange dual-emissive carbon dots for pH sensing and cell imaging显示文摘The dual-emissive N,S co-doped carbon dots (N,S-CDs) with a long emission wavelength were synthesized via solvothermal method.The N,S-CDs possess relatively high photoluminescence (PL) quantum yield (QY) (35.7%) towards near-infrared fluorescent peak up to 648 nm.With the advanced characterization techniques including X-ray photoelectron spectroscopy (XPS),Fourier transform infrared spectroscopy (FTIR),etc.It is found that the doped N,S elements play an important role in the formation of high QY CDs.The N,S-CDs exist distinct pH-sensitive feature with reversible fluorescence in a good linear relationship with pH values in the range of 1.0-13.0.What is more,N,S-CDs can be used as an ultrasensitive Ag+ probe sensor with the resolution up to 0.4 μM.This finding will expand the application of as prepared N,S-CDs in sensing and environmental fields. | Miaoran Zhang Rigu Su Jian Zhong Ling Fei Wei Cai Qingwen Guan Weijun Li Neng Li Yusheng Chen Lulu Cai Quan Xu | 2019 | Nano Research2019，12，4： | 6 |
| 6 | Microstructure Characteristics and Mechanical Properties of Nb-17Si-23Ti Ternary Alloys Fabricated by In Situ Reaction Laser Melting Deposition显示文摘Fabrication of ternary Nb–17 Si–23 Ti alloys was attempted by in situ reaction laser melting deposition(LMD)with dual powder feeding method from Nb-28 at.% Ti powder mixture and pure Si powder. The microstructures of the asdeposited alloys were examined with scanning electronic microscope, and the phase constituents were analyzed by X-ray energy-dispersive spectrometer and X-ray diffraction. Furthermore, the effect of laser power on microstructure characteristics, microhardness and indentation fracture toughness was also investigated. The in situ reaction LMD process resulted in remarkable refinement of the microstructure. The as-deposited samples mainly consisted of NbSS,metastable(Nb Ti)3 Si and Ti-rich NbSS. With the increase in the laser power from 1000 to 2000 W, the NbSSmorphology changed from discontinuous dendritic to near equiaxed, but the Ti-rich NbSSphase tended to vanish. Furthermore, with the increase in the laser power, the microhardness of as-deposited samples increased from 822 to 951 HV, while the indentation fracture toughness was improved from 12.3 to 14.1 MPa m1/2. The corresponding mechanism is also discussed. | Wei Liu Hua-Ping Xiong Neng Li Shao-Qing Guo Ren-Yao Qin | 2018 | Acta Metallurgica Sinica(English Letters)2018，31，4： | 5 |
| 7 | A flow cytometer based protocol for quantitative analysis of bloom-forming cyanobacteria(Microcystis) in lake sediments显示文摘A quantitative protocol for the rapid analysis of Microcystis cells and colonies in lake sediment was developed using a modified flow cytometer,the CytoSense.For cell enumeration,diluted sediment samples containing Microcystis were processed with sonication to disintegrate colonies into single cells.An optimized procedure suggested that 5 mg dw(dry weight)/mL dilution combined with 200 W × 2 min sonication yielded the highest counting efficiency.Under the optimized determination conditions,the quantification limit of this protocol was 3.3×10 4 cells/g dw.For colony analysis,Microcystis were isolated from the sediment by filtration.Colony lengths measured by flow cytometry were similar to those measured by microscopy for the size range of one single cell to almost 400 μm in length.Moreover,the relationship between colony size and cell number was determined for three Microcystis species,including Microcystis flos-aquae,M.aeruginosa and M.wessenbergii.Regression formulas were used to calculate the cell numbers in differentsized colonies.The developed protocol was applied to field sediment samples from Lake Taihu.The results indicated the potential and applicability of flow cytometry as a tool for the rapid analysis of benthic Microcystis.This study provided a new capability for the high frequency monitoring of benthic overwintering and population dynamics of this bloom-forming cyanobacterium. | Quan Zhou Wei Chen Huiyong Zhang Liang Peng Liming Liu Zhiguo Han Neng Wan Lin Li Lirong Song | 2012 | Journal of Environmental Sciences2012，24，9： | 5 |
| 8 | Month-Wise Prevalence of Subclinical Mastitis in Dairy Cows in Guangdong Province,China显示文摘To evaluate the month-wise prevalence of subclinical mastitis (SM) and its relations with climatic temperature and humidity, and to provide references for control and prevention of mastitis in dairy cows in Guangdong, China, California mastitis test method was used to determine the monthly prevalence of SM (MPSM, %) of lactating Holstein cows from 11 dairy farms in Guangdong Province, China, including about 516 cows per monthly examination. The average MPSM on a cow and a quarter basis were 30 and 13% respectively, and there was a positive linear correlation between monthly mean air temperature (MT, °C) and MPSM on a cow basis (r=0.763, P=0.004) or a quarter basis (r=0.577, P=0.049), but there were no correlations between MT and MPSM on a cow or a quarter basis (P>0.05). There was a shift in MPSM trend that the highest MPSM (38.4%) was not for the hottest July with MT at 30.8°C, but for the later September at 27.9°C. The farms need to develop new housing conditions to control cowshed temperatures in the hot season to reduce the mastitis prevalences in the post-hot months. | YANG Jin-bo WEI Neng WEN Liu-fa | 2012 | Journal of Integrative Agriculture2012，11，1： | 5 |
| 9 | Laser Additive Manufacturing on Metal Matrix Composites: A Review显示文摘Important progresses in the study of laser additive manufacturing on metal matrix composites(MMCs)have been made.Recent efforts and advances in additive manufacturing on 5 types of MMCs are presented and reviewed.The main focus is on the material design,the combination of reinforcement and the metal matrix,the synthesis principle during the manufacturing process,and the resulted microstructures as well as properties.Thereafter,the trend of development in future is forecasted,including:Formation mechanism and reinforcement principle of strengthening phase;Material and process design to actively achieve expected performance;Innovative structure design based on the special properties of laser AM MMCs;Simulation,monitoring and optimization in the process of laser AM MMCs. | Neng Li Wei Liu Yan Wang Zijun Zhao Taiqi Yan Guohui Zhang Huaping Xiong | 2021 | Chinese Journal of Mechanical Engineering2021，34，3： | 4 |
| 10 | Research Progress of Refractory High Entropy Alloys:A Review显示文摘Owing to superior comprehensive performance than conventional superalloys at high temperature,refractory high entropy alloy(RHEA)is becoming a promising candidate for the next generation high-temperature material.Herein,contemporary aspects of corresponding development of RHEAs are reviewed to discuss various factors affecting the organization structure and service performance.It mainly covers alloying system and strengthening mechanism,the preparation method,plastic deformation and the related mechanism,as well as microstructure control by heat treatment.Firstly,the alloy systems and strengthening mechanism are introduced.This is followed by different preparation methods and the comparison of strengths and shortcomings based on different RHEAs.Then,hot deformation behavior and plastic deformation under different loadings are analyzed.Based on this,the influence of heat treatment on microstructures prior to and after the deformation is further summarized.Finally,some important research areas to be carried out in future are pointed out.This review will give a deep understanding of the effects of different factors on the service performance and provide scientific guide in designing RHEAs with improved performance. | Xiaochang Xie Neng Li Wei Liu Shuai Huang Xiaoyong He Qiuying Yu Huaping Xiong Enhui Wang Xinmei Hou | 2022 | Chinese Journal of Mechanical Engineering2022，35，6： | 4 |
| 11 | Generation of strong magnetic fields with a laser-driven coil显示文摘As a promising new way to generate a controllable strong magnetic field, laser-driven magnetic coils have attracted interest in many research fields. In 2013, a kilotesla level magnetic field was achieved at the Gekko XⅡ laser facility with a capacitor–coil target. A similar approach has been adopted in a number of laboratories, with a variety of targets of different shapes. The peak strength of the magnetic field varies from a few tesla to kilotesla, with different spatiotemporal ranges. The differences are determined by the target geometry and the parameters of the incident laser. Here we present a review of the results of recent experimental studies of laser-driven magnetic field generation, as well as a discussion of the diagnostic techniques required for such rapidly changing magnetic fields. As an extension of the magnetic field generation, some applications are discussed. | Zhe Zhang Baojun Zhu Yutong Li Weiman Jiang Dawei Yuan Huigang Wei Guiyun Liang Feilu Wang Gang Zhao Jiayong Zhong Bo Han Neng Hua Baoqiang Zhu Jianqiang Zhu Chen Wang Zhiheng Fang Jie Zhang | 2018 | High Power Laser Science and Engineering2018，6，3： | 2 |
| 12 | Traditional knowledge, use and conservation of plants by the communities of Tharaka-Nithi County, Kenya显示文摘Rural communities in Kenya largely depend on plant resources for their livelihood.The utilization of these resources depends on the availability of plant resources and the level of knowledge of the residents.We conducted an ethnobotanical study in Tharaka-Nithi County in Kenya to determine the knowledge and utilization of various plant species by the local communities.The study was conducted in four major administrative regions from June 2018 to February 2019,involving interview schedules using semi-structured open-ended questionnaires and guided field collections with 48 informants.A total of 214 plant species distributed in 73 families and 169 genera with 616 Use Reports(URs)were documented.Fabaceae was the highest family cited by the informants(31 species)followed by Lamiaceae and Euphorbiaceae(each with 11 species).Trees(49%)and shrubs(32%)were the top life forms of the plants frequently utilized by the local residents.The general plant uses reported were medicinal,food,fodder,construction,fuel,pesticidal,religious,live fencing,and making crafts.Zanthoxylum gilletii,Prunus africana,and Solanum incanum were found to be highly valued by the local communities.Plant utilization as food and medicinal uses against snake-bite related problems had the highest Informant Consensus Factor(ICF).Only 29(13.6%)of the species reported had their status assessed by the International Union for Conservation of Nature(IUCN).Conservation measures,alongside awareness creation in this region,are highly recommended for the species endemic to the region,highly depended on by the community,and those threatened according to IUCN standards. | Vivian Kathambi Fredrick Munyao Mutie Peninah Cheptoo Rono Neng Wei Jacinta Ndunge Munyao Peris Kamau Robert Wahiti Gituru Guang-Wan Hu Qing-Feng Wang | 2020 | Plant Diversity2020，42，6： | 2 |
| 13 | Target alignment in the Shen-Guang Ⅱ Upgrade laser facility显示文摘The Shen-Guang II Upgrade(SG-Ⅱ-U) laser facility consists of eight high-power nanosecond laser beams and one shortpulse picosecond petawatt laser. It is designed for the study of inertial confinement fusion(ICF), especially for conducting fast ignition(FI) research in China and other basic science experiments. To perform FI successfully with hohlraum targets containing a golden cone, the long-pulse beam and cylindrical hohlraum as well as the short-pulse beam and cone target alignment must satisfy tight specifications(30 and 20 μm rms for each case). To explore new ICF ignition targets with six laser entrance holes(LEHs), a rotation sensor was adapted to meet the requirements of a three-dimensional target and correct beam alignment. In this paper, the strategy for aligning the nanosecond beam based on target alignment sensor(TAS) is introduced and improved to meet requirements of the picosecond lasers and the new six LEHs hohlraum targets in the SG-II-U facility. The expected performance of the alignment system is presented, and the alignment error is also discussed. | Lei Ren Ping Shao Dongfeng Zhao Yang Zhou Zhijian Cai Neng Hua Zhaoyang Jiao Lan Xia Zhanfeng Qiao Rong Wu Lailin Ji Dong Liu Lingjie Ju Wei Pan Qiang Li Qiang Ye Mingying Sun Jianqiang Zhu Zunqi Lin | 2018 | High Power Laser Science and Engineering2018，6，1： | 2 |
| 14 | Different position from traditional left lateral for colonoscopy? A meta-analysis and systematic review of randomized control trials显示文摘Background: Colonoscopy requires the intubation of the cecum for screening of colorectal diseases. The conventional position used for colonoscopy is the left lateral position (LLP). However, alternative positions have also been utilized to enhance the success of intubation. Thus, the aim of this study was to perform a meta-analysis of the different positions to determine the effectiveness of the individual positions for successful colonoscopy.Methods: Medline, Embase and Cochrane trials electronic databases were searched for studies on colonoscopy positions. The primary outcome was defined as the cecal intubation rate. Pooled risk ratios (RR) and 95% confidence intervals (CI) for the rates of cecal intubation were estimated. Secondary outcomes such as the cecal intubation time and adenoma detection rate were further analyzed qualitatively.Results: After reviewing 644 identified records, 7 randomized control trials (RCT) studies were included. No significant difference was observed in either comparisons, between the LLP vs. supine position (SP) (RR = 1.01, 95% CI, 0.98 to 1.04,P = 0.55) or the LLP vs. prone position (PP) (RR = 1.02, 95% CI, 0.98 to 1.06,P = 0.27).Conclusions: Amidst available literature, the use of other positions can be considered when performing colonoscopy. These further highlights that the existential practice is based predominantly on familiarity instead of evidence-based-research. | Snow Yunni Lin Clyve Yu Leon Yaow Cheng Han Ng Neng Wei Wong Hui Yu Tham Choon Seng | 2021 | Chronic Diseases and Translational Medicine2021，7，1： | 1 |
| 15 | Mechanism study on the frequent variations of cell-bound microcystins in cy- anobacterial blooms in Lake Taihu: implications for water quality monitoring and assessments 显示文摘 | Chen Wei Peng Liang Wan Neng | 2009 | Chemosphere2009，77，11： | 1 |
| 16 | Laboratory development of high performance steel plates with excellent HAZ toughness at large heat inputs显示文摘Presented in this study is the result of steel plates developed at laboratory by using the technique of chemistry design based on microstructure evolution.It has been shown that the produced 50mm thickness steel plates with yield and tensile strength being 420 MPa and 530 MPa respectively exhibit excellent large heat input weldability:the Charpy impact tests in the whole range of heat affected zone(HAZ) including the fusion line at the welded joint with large heat input of 100 -300 kJ/cm showed uniform impact toughness of above 140 J at -40℃.Welding simulations were also performed for heat inputs of 200-600 kJ/cm,which showed far better toughness at -20℃.Analysis on the results of the simulations and the practical welding tests were done and the microstructure evolution mechanisms were proposed.Finally suggestions were given to improve the simulation processes as well as chemistry modification. | WANG Wei,WANG Huanrong,BAI Yan,CAO Neng,QU Zhaoxia,WANG Haitao and LIU Gang Research Institute,Baoshan Iron & Steel Co.,Ltd.,Shanghai 201900,China | 2010 | Baosteel Technical Research2010，4，S1： | 1 |
| 17 | Preparation and Functional Design of Polyethyleneimine Reinforced Nanocellulose-based Aerogel显示文摘An aerogel electrode composed of conductive active materials based on nanocellulose aerogels can absorb more electrolytes,as well as enhance electron transport and ion diffusion channels.In the present study,aerogels with high strength were successfully prepared using 2,2,6,6-tetramethyl-1-piperidinyloxy free radical(TEMPO)-oxidized cellulose nanofibrils(CNF)as a raw material and polyethyleneimine(PEI)as a crosslinking agent.Simultaneously,functional electrode materials were prepared via self-assembly.Based on our findings,PEI can significantly improve the water and solvent solubility and enhance the wet strength and shape recovery ability of CNF aerogels.Meanwhile,the minimum density of the aerogel reached 0.0160 g/cm3,the maximum porosity was approximately 98.5%,and the maximum stress approximated 0.02 MPa.Furthermore,electrochemical tests revealed that after self-assembly of reduced graphene oxide(RGO)and polyaniline(PANI)solution,the mass specific capacitance of the functional composite aerogel was approximately 92 F/g and exhibited good chargedischarge performance. | Jiacheng Lin Tao Lin Xuefeng Yin Xue Cai Xiaoyao Wei Neng Zhang | 2022 | Paper And Biomaterials2022，7，1： | 1 |
| 18 | Design and performance of final optics assembly in SG-ⅡUpgrade laser facility显示文摘In high power laser facility for inertial confinement fusion research, final optics assembly(FOA) plays a critical role in the frequency conversion, beam focusing, color separation, beam sampling and debris shielding. The design and performance of FOA in SG-II Upgrade laser facility are mainly introduced here. Due to the limited space and short focal length, a coaxial aspheric wedged focus lens is designed and applied in the FOA configuration. Then the ghost image analysis,the focus characteristic analysis, the B integral control design and the optomechanical design are carried out in the FOA design phase. In order to ensure the FOA performance, two key technologies are developed including measurement and adjustment technique of the wedged focus lens and the stray light management technique based on ground glass.Experimental results show that the design specifications including laser fluence, frequency conversion efficiency and perforation efficiency of the focus spot have been achieved, which meet the requirements of physical experiments well. | Zhaoyang Jiao Ping Shao Dongfeng Zhao Rong Wu Lailin Ji Li Wang Lan Xia Dong Liu Yang Zhou Lingjie Ju Zhijian Cai Qiang Ye Zhanfeng Qiao Neng Hua Qiang Li Wei Pan Lei Ren Mingying Sun Jianqiang Zhu Zunqi Lin | 2018 | High Power Laser Science and Engineering2018，6，2： | 1 |
| 19 | SideKnot:Edge Bundling for Uncovering Relation Patterns in Graphs显示文摘The node-link diagram is an intuitive way to depict a graph and present relationships between entities.Addressing the visual clutter induced by edge crossing and node-edge overlapping is a challenging task as the size of graph outgrows the visualization space.Many edge bundling methods are proposed to disclose high-level edge patterns.Though previous methods can successfully reveal the skeleton graph structure,the relation patterns at the individual node level can be overlooked.In addition,most edge bundling algorithms are computationally complex,which prevents them from scaling up for extremely large graphs.In this article,we extend SideKnot,an efficient edge bundling method to cluster and knot edges at the node side.Our proposed method is light,runs faster than most existing algorithms,and can reveal the relation patterns at the individual node level.Our results show that SideKnot can disclose a node's standing in the graph as well as the directional connection patterns to its peers. | Dichao Peng Neng Lu Guangyu Chen Wuheng Zuo Wei Chen Qunsheng Peng | 2012 | Tsinghua Science and Technology2012，17，4： | 1 |
| 20 | Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins显示文摘 | Wang Zhiyu Cheng Yue Wang Neng Wang Dong Mei Li Ying Wei Han Feng Shen Jian Gang Yang De Po Guan Xin Yuan Chen Jian-Ping | 2012 | Cancer Biology & Therapy2012，，3： | 1 |
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