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| 1 | Free-breathing radial volumetric interpolated breathhold examination vs breath-hold cartesian volumetric interpolated breath-hold examination magnetic resonance imaging of the liver at 1.5T显示文摘AIM: To compare breath-hold cartesian volumetric interpolated breath-hold examination(cVIBE) and freebreathing radial VIBE(rVIBE) and determine whether rVIBE could replace cVIBE in routine liver magnetic resonance imaging(MRI).METHODS: In this prospective study, 15 consecutive patients scheduled for routine MRI of the abdomen underwent pre- and post-contrast breath-hold cVIBE imaging(19 s acquisition time) and free-breathing rVIBE imaging(111 s acquisition time) on a 1.5T Siemens scanner. Three radiologists with 2, 4, and 8 years post-fellowship experience in abdominal imaging evaluated all images. The radiologists were blinded to the sequence types, which were presented in a random order for each patient. For each sequence, the radiologists scored the cVIBE and rVIBE images for liver edge sharpness, hepatic vessel clarity, presence of artifacts, lesion conspicuity, fat saturation, and overall image quality using a five-point scale. RESULTS: Compared to rVIBE, cVIBE yielded significantly(P < 0.001) higher scores for liver edge sharpness(mean score, 3.87 vs 3.37), hepatic-vessel clarity(3.71 vs 3.18), artifacts(3.74 vs 3.06), lesion conspicuity(3.81 vs 3.2), and overall image quality(3.91 vs 3.24). cVIBE and rVIBE did not significantly differ in quality of fat saturation(4.12 vs 4.03, P = 0.17). The inter-observer variability with respect to differences between rVIBE and cVIBE scores was close to zero compared to random error and inter-patient variation. Quality of rVIBE images was rated as acceptable for all parameters. CONCLUSION: rVIBE cannot replace cVIBE in routine liver MRI. At 1.5T, free-breathing rVIBE yields acceptable, although slightly inferior image quality compared to breath-hold cVIBE. | Sireesha Yedururi HyunSeon C Kang Wei Wei Nicolaus A Wagner-Bartak Leonardo P Marcal R Jason Stafford Brandy J Willis Janio Szklaruk | 2016 | World Journal of Radiology2016，8，7： | 9 |
| 2 | 笋芽顶端分生组织在竹秆横切面形态形成中的作用与机制研究显示文摘竹秆的横切面主要由表皮、皮层、维管组织、基本组织及髓腔(早期为髓组织)组成。这些组织均由笋芽茎顶端分生组织分化发育而来,且其在生长发育过程中促使了竹秆横切面形态(本文特指:竹秆横切面外轮廓形状、围度及壁-腔结构)的形成。然而,人们对于这一生长发育过程的生物学机制知之甚少。本研究利用解剖学、数学模拟等方法,对 20 种具不同秆径竹种的笋芽顶端分生组织进行了分析。研究结果发现,笋芽顶端分生组织指状形态的维持是竹子产生圆柱形竹秆的基础;在顶端分生组织细胞数目增加的同时,线性增加原体细胞数目应是竹子在演化过程中产生大径竹秆且保持规则壁-腔结构的方式。进一步通过研究一个竹壁增厚且壁-腔架构紊乱的稳定变异体———实肚竹( Phyllostachys nidularia f. farcta)发现,其笋芽顶端分生组织细胞数目减少且原体/原套细胞数比值降低使其产生了高比例的壁组分组织(指基本分生组织与肋状分生组织)与低比例的髓组织。上述 2 种组织的比例失衡,使得实肚竹笋芽在后续发育中壁组分组织随机挤入到了髓组织中,最终形成了实肚竹异常的竹秆横切面形态(竹壁多样化增厚且壁-腔结构紊乱)。此外,相对较小的顶端分生组织,使得实肚竹笋芽产生了较少的内源激素,如其生长素含量仅约为其原种篌竹的 67. 5%,各细胞分裂素含量也显著低于篌竹笋芽。转录组分析进一步发现,在实肚竹笋芽中与激素及代谢相关的功能基因呈显著下调表达。这些生理与分子变化最终导致了实肚竹竹秆矮化、秆径减小且生物量降低。本论文的研究结果为研究竹秆横切面发育提供了一个重要的视角,同时也为实肚竹厚壁茎秆的形成提出了一个合理的机制。 | Wang Y Sun X Ding Y Fei Z Jiao C Fan M Yao B Xin P Chu J Wei Q 王雨珺 魏强 | 2019 | 世界竹藤通讯2019，17，3： | 5 |
| 3 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013，23，9： | 3 |
| 4 | Effects of incubation temperatures on embryonic development in the Asian yellow pond turtle 显示文摘 | Zhu X P Wei C Q Zhao W H | 2006 | Aquaculture2006，259，： | 1 |
| 5 | Characterization and comparative profiling of the small RNA transcriptomes in two phases of locust显示文摘 | Wei Y Y Chen S Yang P C | 2009 | Genome Biol2009，10，： | 1 |
| 6 | Comparison of epoxy resins for applications in light - emitting diodes 显示文摘 | Huang J C Chu Y P Wei M | 2004 | Advances in polymer technology2004，23，4： | 1 |
| 7 | Empirical comparison of fast partitio- ning-based clustering algorithms for large data sets 显示文摘 | WEI C P LEE Y H HSU C M | 2003 | Expert Sys- tems with Applications2003，24，4： | 1 |
| 8 | 查看详情显示文摘 | Wang G E Qin W P Zhang J S Zhang J S Wang Y Cao C Y Wang L L Wei G D Zhu P E Wu C E Kim Ryongjin | | 0，，： | 1 |
| 9 | Characterization and comparative profiling of the smallRNA transcriptomes in two phases of locust显示文摘 | Wei Y Y Chen S Yang P C Ma Z Y Le K | 2009 | Genome Bilogy2009，10，： | 1 |
| 10 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 11 | The Synthesis of a Novel Flame Retardant and Its Synergistic Efficiency in Polypropylene/Ammonium Polyphosphate System显示文摘 | WANG C WEI P QIAN Y | 2011 | Polym Adv Technol2011，22，7： | 1 |
| 12 | MicroRNAs: Novel regulators involved in the pathogenesis of psoriasis显示文摘 | Sonkoly E Wei T Janson P C | 2007 | PLoS ONE2007，2，7： | 1 |
| 13 | Efficient EM initializationmethod for time - delay estimation 显示文摘 | YI M WEI P XIAO X C | 2003 | Electronics Letters2003，39，2： | 1 |
| 14 | Identification and characterization of the miRNA transcriptome of ovis aries 显示文摘 | Zhang S F Zhao F P Wei C H Sheng X H Ren H X Xu L Y l u J Liu J S Zhang L Du L X | 2013 | PLoS One2013，8，58： | 1 |
| 15 | DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis显示文摘 | Tan C Qiao F Wei P | 2016 | Mol Carcinog2016，55，4： | 1 |
| 16 | Reeurrence after liver resection for hepatocellular carcinoma: risk factors, treatment, and outcomes 显示文摘 | Shah S A Cleary S P Wei A C | 2007 | Surgery2007，141，3： | 1 |
| 17 | Actuat显示文摘 | Wei B Y Hsu M C Su P G Lin H M Wu R J Lai H J Sensor | 2004 | B2004，101，： | 1 |
| 18 | Identification and functional characterization of the delta 6-fatty acid desaturase gene from Thamnidium elegans显示文摘 | Wang D P Li M C H Wei D S H | 2006 | J Eukaryot Microbiol2006，53，5： | 1 |
| 19 | Support vector machines with simulated annealing algorithms in electricity load forecasting显示文摘 | Ping F P Wei C H | 2005 | Energy Conversion and Management2005，，46： | 1 |
| 20 | Regulation of stress granule dynamicsby Grb7 and FAK signalling pathway显示文摘 | Tsai N P Ho P C Wei L N | 2008 | EMBO J2008，27，5： | 1 |
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