|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation显示文摘AIM To explore the expression of perform andgranzyme B genes mRNA to judge the effect ofimmunosuppression in acute rejection of livertransplantation.METHODS The expression of perform andgranzyme B genes mRNA was examined byreverse transcriptase-polymerase chain reaction(RT--PCR) in hamster to rat liver grafts under theimmunosuppression of cyclosporine or/andsplenectomy. Histological findings were studiedcomparatively.RESULTS Cyclosporine could obviouslydecrease the cellular infiltration, and completelyrepress the expression of mRNA for perform andgranzyme B, but could not change severehepatocyte necrosis and hemorrhage.SPlenectomy could significantly lightenhepatocyte necrosis, and completely eliminatehemorrhage, but not atfect the cellularinfiltration and the expression of perform andgranzyme B genes mRNA. Cyclosporine orsplenectomy alone could not prolong theSurvival time, however, their combination couldcompletely repress the rejection of liver grafts.The survival time of animals were significantlyprolonged (37.1 days ). The architecture ofhepatic lobules was preserved. There was slightcellular infiltration in the portal tracts and noexpression of perform and granzyme B genesmRNA could be seen in three weeks aftertransplantation.CONCLUSION Perform and granzyme B genesare valuable in judging the effect ofimmunosuppression in liver transplantation. | Zhang SG Wu MC Tan JW Chen H Yang JM Qian QJ | 1999 | World Journal of Gastroenterology1999，5，3： | 15 |
| 2 | 不同血管紧张素转换酶抑制剂与高血压患者整体和病因特异性死亡率的相关性显示文摘血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)已广泛用于治疗高血压,比较不同药物降低死亡率有效性的研究却鲜有报道。方法:选取中国台湾地区全民健康保险数据库中从2004年1月1日至2009年12月31日开始用卡托普利、赖诺普利、依那普利、福辛普利、雷米普利、咪达普利或培哚普利治疗的高血压患者。整体和病因特异性死亡率通过中国台湾地区全民死亡登记来证实。从最初用ACEI开始随访患者直至死亡、退出研究或研究终止(2010年12月31日)。 | Chang CH Lin JW Caffrey JL Wu LC Lai MS | 2015 | 中华高血压杂志2015，23，9： | 2 |
| 3 | Development of a rat C6brain tumor model 显示文摘 | Wu JW Gao DK Fei Z Qu Y | 2002 | Chin Med J2002，115，3： | 1 |
| 4 | In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment 显示文摘 | Sipkins DA We i X Wu JW | 2005 | Nature2005，435，7044： | 1 |
| 5 | Structural mechanism of Smad 4recognition by the nuclear oncoprotein Ski:insights on Ski-mediated repression of TGF-beta signaling显示文摘 | Wu JW Krawitz AR Chai J | 2002 | Cell2002，111，3： | 1 |
| 6 | Altered expression of survivin, Fas and FasL contributed to cervicalcancer development and metastasis显示文摘 | Wu SF Zhang JW Qian WY | 2012 | Eur Rev Med Pharmaol Sci2012，16，15： | 1 |
| 7 | Four orchid ( Oncidium Cower Ramsey) API/AGL9-1ike MADS box genes show novel expression patterns and cause different effects on floral transi- tion and formation in Arabidopsis thaliana显示文摘 | Chang YY Chiu YF Wu JW | 2009 | Plant and Cell Physiology2009，50，8： | 1 |
| 8 | Diagnostic value of serum gamma-glutamyl transferase isoenzyme for hepatocellular carcinoma:a 10-year study 显示文摘 | Xu K Meng XY Wu JW | 1992 | Am J Gastroenterol1992，87，： | 1 |
| 9 | First reported cases of intravascular large cell lymphoma of the NK cell type:clinical,histologic,immunophenotypic,and molecular features显示文摘 | Wu H Said JW Ames ED | 2005 | Am J Clin Pathol2005，123，4： | 1 |
| 10 | Structural and biochemical basis of apoptotic activation by Smac/DIABLO 显示文摘 | Chai J Du C Wu JW | 2000 | Nature2000，406，6798： | 1 |
| 11 | A novel reagentless amperometric immunosensor based on gold nanoparticles/TMB/ Nation-modified electrode 显示文摘 | Wu Y Zheng JW Li Z | 2009 | Biosens Bioelectron2009，24，5： | 1 |
| 12 | The pyroptosome:a supramolecular assembly of ASC dimers mediatinginflammatory cell death via caspase-lactivation显示文摘 | Fernandes-Alnemri T Wu J Yu JW | 2007 | Cell DeathDiffer2007，14，9： | 1 |
| 13 | Cryopyrin and pyrin activate easpase-1, but not NF-kappaB, via ASC oligomerization 显示文摘 | Yu JW Wu J Zhang Z | 2006 | Cell Death Differ2006，13，2： | 1 |
| 14 | Vaccinationwith peptide mimetics of the gp41 prehairpin fusionintermediate yields neutralizing antisera against HIV-1isolates 显示文摘 | Bianchi E Joyce JG Miller MD Liang XP Finotto MA McKenna P Citron MA Hepler RW Hrin R Nahas D Wu CW Montefiori D Shiver JW Kim PS | 2010 | Proc Natl Acad Sci USA2010，107，10： | 1 |
| 15 | Development of a rat C6 brain tumor model显示文摘 | Zhang X Wu JW Gao DK | 2002 | Chin Med J2002，115，3： | 1 |
| 16 | Modulation of tea and tea polyphenols on benzo(a) pyrene-induced DNA damage in Chang liver cells显示文摘 | Yen GC Ju JW Wu CH | 2004 | Free Radic Res2004，38，2： | 1 |
| 17 | Structural and biochemical basis of apoptotic activation by Smac/ DIABLO 显示文摘 | Chai J Du C Wu JW | 2000 | Na- ture2000，406，6798： | 1 |
| 18 | Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy显示文摘 | MOUL JW WU H SUN L | 2008 | J Urol2008，179，5： | 1 |
| 19 | Four orchid (Oncidium Gower Ramsey) API/AGL9-1ike MADS-box genes show novel expression patterns and cause different effects on floral transition and formation in Arabidopsis thaliana 显示文摘 | CHANGYY CHIU Y F WU JW | 2009 | Plant Cell Physiol2009，50，8： | 1 |
| 20 | Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation 显示文摘 | Sundar IK Hwang JW Wu S | 2011 | Biochem Biophys Res Commun2011，406，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员