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| 1 | Synthesis of 2, 6-(substituded)pyridine Derivatives Using Amide and Imine Groups显示文摘A new wo-armed?acyclic diamide Ia 2, 6-bis(1-ethanecarbozamido-2-amino)pyridine, and a new series of aromatic aldehyde schiff bases containing pyridine ring and amide bridge, IIa-f, were prepared. The compounds were characterized by elemental analysis, IR, 1HNMR and MS. The bioactivity half inhibitory concentration C1/2 is given. | Mei Ying LI, Pei Zhi HU*, Wan Ren ZHU, Kuo Xi XU College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072 | 2003 | Chinese Chemical Letters2003，14，6： | 9 |
| 2 | Effect of Multiple Coatings of One-step Self-etching Adhesive on Microtensile Bond Strength to Primary Dentin显示文摘Objective To investigate the effect of multiple coatings of the one-step self-etching adhesive on immediate microtensile bond strength to primary dentin.Methods Twelve caries-free human primary molars were randomly divided into 2 groups with 6 teeth each.In group 1,each tooth was hemisected into two halves.One half was assigned to control subgroup 1,which was bonded with a single-step self-etching adhesive according to the manufacturer's instructions;the other half was assigned to experimental subgroup 1 in which the adhesive was applied three times before light curing.In group 2,the teeth were also hemisected into two halves.One half was assigned to control subgroup 2,which was bonded with the single-step self-etching adhesive according to the manufacturer's instructions;the other half was assigned to experimental subgroup 2 in which three layers of adhesive were applied with light curing each successive layer.Microtensile bond strength was immediately tested after specimen preparation.Results When the adhesive was applied three times before light curing,the bond strength of the experimental subgroup 1(n=33,57.49±11.61 MPa) was higher than that of the control subgroup 1(n=31,49.71±11.43 MPa,P<0.05).When using the technique of applying multiple layers of adhesive with light curing each successive layer,no difference of immediate bond strength was observed between the control subgroup 2 and the experimental subgroup 2(P>0.05).Conclusion Multiple coatings of one-step self-etching adhesive can increase the immediate bond strength to primary dentin when using the technique of light-curing after applying three layers of adhesive. | Lin Ma Jian-feng Zhou Jian-guo Tan Quan Jing Ji-zhi Zhao Kuo Wan | 2011 | Chinese Medical Sciences Journal2011，26，3： | 4 |
| 3 | Peginterferon Alfa-2a Plus Ribavirin for the Treatment of Dual Chronic Infection With Hepatitis B and C Viruses显示文摘 | Chun–Jen Liu Wan–Long Chuang Chuan–Mo Lee Ming–Lung Yu Sheng–Nan Lu Shun–Sheng Wu Li–Ying Liao Chi–Ling Chen Hsing–Tao Kuo You–Chen Chao Shui–Yi Tung Sien–Sing Yang Jia–Horng Kao Chen–Hua Liu Wei–Wen Su Chih–Lin Lin Yung–Ming Jeng Pei–Jer Chen Ding–Shinn | 2009 | Gastroenterology2009，，2： | 3 |
| 4 | The Synthesis of 7-[1-Aza-2-(dimethylamino)vinyl]-4-methylhydroquinolin-2-ones and their Isomerism in Different Solvents显示文摘The reaction of 7-amino-4-methyl-2(1H)-quinolone 1 and its 6-methyl derivative 2 with Vilsmeier reagent (DMF and POCl3) afforded 7-[1-aza-2-(dimethylamino)vinyl]-4-methyl- hydro- quinolin-2-one 3 and 7-[1-aza-2-(dimethylamino)vinyl]-4,6-dimethylhydroquinolin- 2-one 4, respec-tively. 1H-NMR analysis in different solvents indicated that isomerism occurred due to hindered rotation around the (CH3)2N-C:N σ-bond. The rotational energy barrier of 3 was calculated. | Qian ZHANG,1 Ying CHEN,1 Yun Hong ZHENG,1 Wan Yun SHENG,1 Peng XIA1* Yi XIA,2 Zheng Yu YANG,2 Kuo Hsiung LEE2 1Department of Organic Chemistry, The School of Pharmacy, Shanghai Medical University, 138 Yi Xue Yuan Road, Shanghai 200032 2Natural Products | 2001 | Chinese Chemical Letters2001，12，1： | 3 |
| 5 | A new classification of nevus of Ota显示文摘 | Huang Wen-hui Wang Hong-wei Sun Qiu-ning Jin Hong-zhong Liu Yue-hua Ma Dong-lai Zuo Ya-gang Zheng He-yi Wan Kuo Jing Quan Zhao Yong-liang | 2013 | Chinese Medical Journal2013，，20： | 3 |
| 6 | Effectiveness and Safety of Computer-controlled Periodontal Ligament Injection System in Endodontic Access to the Mandibular Posterior Teeth显示文摘Objective To evaluate the effectiveness and safety of a computer-controlled periodontal ligament(PDL) injection system to the local soft tissues as the primary technique in endodontic access to mandibular posterior teeth in patients with irreversible pulpitis.Methods A total of 162 Chinese patients who had been diagnosed with irreversible pulpitis in their mandibular posterior teeth without acute infection or inflammation in the periodontal tissues were enrolled in this clinical study.The patients were divided into 3 groups according to the position of the involved tooth:the premolar group(PM,n=38),first molar group(FM,n=66),and second molar group(SM,n=58).All the patients received computer-controlled PDL injection with 4% articaine and 1∶100 000 epinephrine.Immediately after the injection,endodontic access was performed,and the degree of pain during the treatment was evaluated by the patients using Visual Analogue Scale for pain.The success rates were compared among the 3 groups.The responses of local soft tissues were evaluated 3-8 days and 3 weeks after the procedure.Results The overall success rate was 76.5%.There was a significant difference in success rates among the PM,FM,and SM groups(92.1%,53.0%,93.1%,respectively;χ2=34.3,P<0.01).Both the PM and SM groups showed higher success rates than that of the FM group(v=1,χ2=16.73,P<0.01;v=1,χ2=24.5,P<0.01).No irreversible adverse effects on the periodontal soft tissues at the injection sites were observed in the follow-up visits in any of the groups.Conclusion The computer-controlled PDL injection system demonstrates both satisfactory anesthetic effects and safety in local soft tissues as primary anesthetic technique in endodontic access to the mandibular posterior teeth in patients with irreversible pulpitis. | Quan Jing Kuo Wan Xiao-jun Wang Lin Ma | 2014 | Chinese Medical Sciences Journal2014，29，1： | 3 |
| 7 | Medical Emergencies in Dental Clinics: A Survey of 2013 Dentists in China显示文摘Objective To investigate the feature and frequency of medical emergencies in dental clinics in China and the Methods A survey study was conducted among 2408 dentists who attended continuing educational courses held by Society of Sedation and Analgesia of Chinese Stomatological Association in 18 cities from December 2015 to December 2018.Demographic information of the dentists and the characteristics of medical emergencies they encountered were collected and analyzed.The associated demographic features for dentist experiencing medical emergencies were analyzed by logistic regression model.Results A total of 2013 dentists provided valid responses and reported 2923 events of medical emergencies in dental clinics.Among them,85.0%reported that they had encountered medical emergencies,and 35.5%had encountered at least twice.Syncope(35.9%)and hypoglycemia(30.3%)were the most common reported medical emergencies.Medical emergencies were most likely to occur during local anesthesia(49.9%),out-patient oral surgery(25.9%),and root canal treatment(11.3%).There were 6 patients(0.2%)died in emergencies.84.0%dentists reported that they had never received training courses about medical emergency management in dentistry other than Basic Life Support.Longer practicing time(10-15 years)(OR=0.59,95%CI:0.41-0.85,P=0.004),working in private dental facilities(OR=1.69,95%CI:1.20-2.38,P=0.003)were associated with an increased risk of experiencing medical emergencies.Conclusion More efforts are needed in prevention,early identification,and timely management of medical emergencies in dental clinics in order to prevent fatal outcomes.The results of this survey are useful information for re-designing emergency training courses for Chinese dentists. | Quan Jing Kuo Wan Lin Ma Jizhi Zhao | 2020 | Chinese Medical Sciences Journal2020，35，4： | 2 |
| 8 | BLOOD PRESSURE CHANGES OF ELDERLY HYPERTENSIVE PATIENTS DURING DENTAL EXTRACTION UNDER SEDATION WITH CONTINUOUS INTRAVENOUS INFUSION OF MIDAZOLAM显示文摘Objective To evaluate the changes in blood pressure (BP) of elderly hypertensive patients having dental extraction under sedation with continuous intravenous infusion of midazolam. Methods One hundred elderly hypertensive patients undergoing dental extraction were recruited for this single-blind, randomized, controlled study. Patients in intervention group (n=50) were given midazolam dissolved in glucose solution and patients in control group (n=50) were given glucose solution only with communication technique. Systolic BP (SBP) and diastolic BP (DBP) were recorded in five time points. Results Under basal conditions, intervention group did not show significant difference in BP compared with control group. Before sedation, mean values of SBP and DBP (especially SBP) significantly increased compared with basal conditions in both groups (P<0.05). During dental extraction sessions, mean values of BP in intervention group significantly decreased than control group (P<0.05), but coefficient of variation did show significant difference in both groups. Conclusion Continuous intravenous infusion of midazolam has been proved to be very successful in controlling BP of elderly patients having dental extraction. | Ji-zhi Zhao Kuo Wan Quan Jing Xi Chen | 2007 | Chinese Medical Sciences Journal2007，22，2： | 2 |
| 9 | A new approach to image retrieval with hierarchical color clustering 显示文摘 | WAN Xia KUO C C J | 1998 | IEEE Transactions on Circuits and Systems for Video Tech- nology1998，8，5： | 1 |
| 10 | Recent advances in optimal reliability allocation显示文摘 | KUO W WAN R | 2007 | IEEE Transactions on Systems Man and Cybernetics Part A: Systems and Humans2007，37，2： | 1 |
| 11 | On the microwave sintering technology for improving the properties of semiconducting electronic ceramics显示文摘 | Lin I N Wan Chulee Kuo Shung | 2001 | Journal of the European Ceramic Society2001，21，： | 1 |
| 12 | Recent advances in optimal reliability allocation显示文摘 | KUO W WAN R | 2007 | IEEE Transactions on Systems Man and Cybernetics Part A:Systems and Humans2007，37，2： | 1 |
| 13 | A new approach to inaage retrieval with hierarchical color clustering显示文摘 | Wan X Kuo C J | 1998 | lEEE Transactions on Circuits and Systems for Video technology1998，8，5： | 1 |
| 14 | Recent advances in optimal reliability allocation 显示文摘 | Kuo W Wan R | 2007 | IEEE Transactions on Systems Man and Cybernetics -- Part A: Systems and Humans2007，37，2： | 1 |
| 15 | Nano-gold supported on TiO2 coated glass-fiber for removing toxic CO gas from air 显示文摘 | Kuo Chien-Nan Chen Huang-Fu Lin Jiunn-Nan Wan Ben-Zu | 2007 | Catalysis Today2007，122，34： | 1 |
| 16 | Modified Grey Model for Estimating Traffic Tunnel Air Quality显示文摘 | Cheng-- Chung Lee Terng-- Jou Wan Chao-- Yin Kuo | 2007 | Environ Moint Assess2007，，132： | 1 |
| 17 | Recent advances in optimal reliability alloca-tion显示文摘 | Kuo Way Wan Rui | | 0，，： | 1 |
| 18 | Recent advances in optimal reliability allocation显示文摘 | Kuo Way Wan Rui | 2007 | IEEE Trans Systems Man and Cybernetics-Part A: Systems and Humans2007，37，2： | 1 |
| 19 | Recent Advances in Optimal Reliability Allocation 显示文摘 | Kuo W Wan Rui | 2007 | IEEE Transactions on Systems Man and Cybernetics2007，37，2： | 1 |
| 20 | Modified grey model for estimating traffic tunnel air quality显示文摘 | Lee Cheng-Chung Wan Terng-Jou Kuo Chao-Yin | 2007 | Environmental Monitoring and Assessment2007，0307，： | 1 |
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