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| 1 | Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma显示文摘BACKGROUND: The indocyanine green (ICG) retention test is the most popular liver function test for selecting patients for major hepatectomy. Traditionally, it is done using spectrophotometry with serial blood sampling. The newly- developed pulse spectrophotometry is a faster alternative, but its accuracy on Child-Pugh A cirrhotic patients undergoing hepatectomy for hepatocellular carcinoma has not been well documented. This study aimed to assess the accuracy of the LiMON , one of the pulse spectrophotometry systems, in measuring preoperative ICG retention in these patients and to devise an easy formula for conversion of the results so that they can be compared with classical literature records where ICG retention was measured by the traditional method. METHODS: We measured the liver function of 70 Child-Pugh A cirrhotic patients before hepatectomy for hepatocellular carcinoma from September 2008 to January 2009. ICG retention at 15 minutes measured by traditional spectrophotometry (ICGR15) was compared with ICG retention at 15 minutes measured by the LiMON (ICGR15(L)). RESULTS: The median ICGR15 was 14.7% (5.6%-32%) and the median ICGR15(L) was 10.4% (1.2%-28%). The mean difference between them was -4.3606. There was a strong correlation between ICGR15 and ICGR15(L) (correlation coefficient, 0.844; 95% confidence interval, 0.762-0.899). The following formula was devised: ICGR15=1.16×ICGR15(L)+2.73.CONCLUSIONS: The LiMON provides a fast and repeatable way to measure ICG retention at 15 minutes, but with constant underestimation of the real value. Therefore, when comparing results obtained by traditional spectrophotometry and the LiMON, adjustment of results from the latter is necessary, and this can be done with a simple mathematical calculation using the above formula. | Tan To Cheung See Ching Chan Kenneth SH Chok Albert CY Chan Wan Ching Yu Ronnie TP Poon Chung Mau Lo Sheung Tat Fan | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 8 |
| 2 | Au@Y203: Eu3+ rare earth oxide hollow sub-microspheres with encapsulated gold nanoparticles and their optical properties 显示文摘 | Min YL Wan Y Yu SH | 2009 | Solid State Sci2009，11，： | 1 |
| 3 | Lung isehemia-reperfusion in- duced gene expression显示文摘 | Calvin SH Connie WC Wan S | 2010 | European Journal of Cardio-thoraeic Sur- gery2010，37，： | 1 |
| 4 | Transforming growth factor- beta and the immune response : implications for anticancer therapy 显示文摘 | Wrzesinski SH Wan YY Flavell RA | 2007 | Clin Cancer Res2007，13，181： | 1 |
| 5 | Adult ovarian granulosa cell tumor:spectrum of sonographic and CT findings with pathologic correlation显示文摘 | Ko SF Wan YL Ng SH | 1999 | AJR1999，172，5： | 1 |
| 6 | Correlation of tramadol pharmacokinetics and CYP2D6 * 10 genotype in Malaysian subjects显示文摘 | Gan SH Ismail R Wan Adnan WA | 2002 | J Pharm Biomed Anal2002，30，2： | 1 |
| 7 | Population pharmacoki-netic modelling of tramadol with application of the NPEM algorithms显示文摘 | Gan SH Ismail R Wan Adnan WA | | 0，，： | 1 |
| 8 | Impact of CYP2D6 genetic polymorphism on tramadol pharmacokinetics and pharmacodynamics显示文摘 | Gan SH Ismail R Wan Adnan WA | 2007 | Mol Diagn Ther2007，11，： | 1 |
| 9 | An algorithm for scheduling a large pumped storage plant显示文摘 | Cohen AI Wan SH | | 0，，08： | 1 |
| 10 | Method development and validation of a high - performance liquid chromatographic method for tramadol in human plasma using liquid - liquid extraction 显示文摘 | Gan SH Ismail R Wan Adrian WA | 2002 | J Chromatogr B2002，772，： | 1 |
| 11 | Transforming growth factor-β and the immune response:Implications for anticancer therapy显示文摘 | Wrzesinski SH Wan YY Flavell RA | 2007 | Clin Cancer Res2007，13，18： | 1 |
| 12 | The effect of early and intensive statin therapy on ventricular premature beat or nonsustained ventricular tachycardia in patients with acute coronary syndrome显示文摘 | He XZ Zhou SH Wan XH | 2011 | clin cardiol2011，34，1： | 1 |
| 13 | Enhanced Desorption of Hexachlorobenzene from Kaolin by Single and Mixed Surfactants显示文摘 | YUAN SH SHU Z WAN J Z | 2007 | Journal of Colloid and Interface Science2007，314，1： | 1 |
| 14 | Population pharmacokinetic modelling of tramadol with application of the NPEM algorithms显示文摘 | Gan SH Ismail R Wan Adnan WA | | 0，，05： | 1 |
| 15 | Fuzzy support vector mac-hines显示文摘 | Lin C F Wan Sh D | | 0，，02： | 1 |
| 16 | Myocardial revascularization:surgery or stenting显示文摘 | Wong SH Wan S | 2007 | Asian Cardiovasc Thorac Ann2007，，15： | 1 |
| 17 | Polyelectrolyte complexesof sodium alginate with chitosan or its derivatives formicrocapsules显示文摘 | Kuen YL Won HP Wan SH | 1997 | Journal of Applied Polymer Science1997，63，4： | 1 |
| 18 | Comparison of cerebral occipital gray and parietal white matter metabolite differences using PRESS and STEAM at different echo times显示文摘 | Wan YL Chang C Ng SH | 1998 | Changgeng Yi Xue Za Zhi1998，21，2： | 1 |
| 19 | Fuzzy support vector machines 显示文摘 | LIN C F WAN SH D | 2002 | IEEE Transactions on Neural Networks2002，13，2： | 1 |
| 20 | MRI ofthoracic vascular lesions with emphasis on two - dimensional time - of - flight MR angiography 显示文摘 | Ko SF Wan YL Ng SH | 1999 | Br J Radiol1999，72，6： | 1 |
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