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| 1 | Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, ameliorates hepatic fibrosis in rats with type 2 diabetes显示文摘 | Zhou Hong Fang Caixia Zhang Lihui Deng Yonggui Wang Mian Meng Fengling | 2014 | Chinese Medical Journal2014，，2： | 20 |
| 2 | The uptake diversity of soil nitrogen nutrients by main plant species in Kobresia humilis alpine meadow on the Qinghai-Tibet Plateau显示文摘We studied the uptake of ammonium,nitrate,and a variety of amino acids by alpine plant species in the Kobresia humilis alpine meadow ecosystem in situ.We examined the extent of niche separation in uptake of N source by different plant species in alpine communities,and investigated the contribution of symbiotically fixed N to the total N in alpine meadow.The results are(1) δ 15 N natural abundance values of 13 plant species lie between 2.680‰ and 5.169‰,and the scope is 7.849‰.(2) Leguminous plants,such as Trigonella ruthenica,Gueldenstaedtia diversiffolia,and Oxytyopis ochrocephala,and non-leguminous plant Gentiana straminea uptake low amounts of 15 N labeled ammonium,nitrate,glycine or aspartate in soil.(3) As far as the plant uptake of organic N is concerned,Kobresia humilis,Poa pratensis,and Gentiuna spathutifolta can effectively uptake organic nitrogen,and about 37%-40% of the nitrogen of these species comes from soil organic nitrogen sources(such as glycine and aspartate).Stipa aliena can effectively uptake nitrate,and 60% of its nitrogen comes from soil nitrate.Potentilla anserina,Poa pratensis,and Thalictrum alpinum can effectively absorb ammonium in comparason to other plant species in the meadow,and about 25%-27% of the nitrogen in these plants comes from soil ammonium.(4) The contribution of leguminous fixed N to total N is 7.48%-9.26% in Kobresia humilis alpine meadow.(5) These data show many plant species of alpine meadow may effectively utilize dissolved organic nitrogen such as amino acids,and these plants have diverse ways to uptake soil nitrogen in alpine meadows.Based on the results we can partly explain why there are abundant biodiversities and how plants at alpine habitat utilize the limited soil N sources. | WANG WenYing MA YongGui XU Jin WANG HuiChun ZHU JinFu ZHOU HuaKun | 2012 | Science China Earth Sciences2012，55，10： | 13 |
| 3 | Development of image-based wheat spike counter through a Faster R-CNN algorithm and application for genetic studies显示文摘Spike number(SN) per unit area is one of the major determinants of grain yield in wheat. Development of high-throughput techniques to count SN from large populations enables rapid and cost-effective selection and facilitates genetic studies. In the present study, we used a deep-learning algorithm, i.e., Faster Region-based Convolutional Neural Networks(Faster R-CNN) on Red-Green-Blue(RGB) images to explore the possibility of image-based detection of SN and its application to identify the loci underlying SN. A doubled haploid population of 101 lines derived from the Yangmai 16/Zhongmai 895 cross was grown at two sites for SN phenotyping and genotyped using the high-density wheat 660 K SNP array.Analysis of manual spike number(MSN) in the field, image-based spike number(ISN), and verification of spike number(VSN) by Faster R-CNN revealed significant variation(P < 0.001) among genotypes, with high heritability ranged from 0.71 to 0.96. The coefficients of determination(R^(2)) between ISN and VSN was 0.83, which was higher than that between ISN and MSN(R^(2)= 0.51), and between VSN and MSN(R^(2)= 0.50). Results showed that VSN data can effectively predict wheat spikes with an average accuracy of 86.7% when validated using MSN data. Three QTL Qsnyz.caas-4 DS, Qsnyz.caas-7 DS, and QSnyz.caas-7 DL were identified based on MSN, ISN and VSN data, while QSnyz.caas-7 DS was detected in all the three data sets. These results indicate that using Faster R-CNN model for image-based identification of SN per unit area is a precise and rapid phenotyping method, which can be used for genetic studies of SN in wheat. | Lei Li Muhammad Adeel Hassan Shurong Yang Furong Jing Mengjiao Yang Awais Rasheed Jiankang Wang Xianchun Xia Zhonghu He Yonggui Xiao | 2022 | The Crop Journal2022，10，5： | 5 |
| 4 | N-Heterocyclic Carbene Organocatalysis: Activation Modes and Typical Reactive Intermediates显示文摘N-Heterocyclic carbene(NHC)organocatalysis has been developed as an important approach in modern organic synthesis.Versatile activation modes within NHC organocatalysis have been established with countless transformations being realized in both efficient and selective fashion.We would like to provide an overview on the key progresses achieved within this field in the past two decades.Since numerous excellent reviews have been documented within this area,we will mainly focus on the scientific development of this research field based on the basic reaction modes and typical reaction intermediates. | Xingkuan Chen Hongling Wang Zhichao Jin Yonggui Robin Chi | 2020 | Chinese Journal of Chemistry2020，38，10： | 5 |
| 5 | Altered functional connectivity networks of hippocampal subregions in remitted late-onset depression:a longitudinal resting-state study显示文摘在迟了生活的消沉(LLD ) 的海马趾的畸形的地区性的特性在以前的研究被表明了。在这研究,我们寻求了检验功能的连接(FC ) 在汇寄的迟了发作的消沉(rLOD ) 的海马趾的分区的模式, LLD 的一种特殊子类型。十四个 rLOD 病人和 18 健康控制象功能的磁性的回声成像在基线并且在 21 月后续扫描的休息状态一样经历了临床、认知的评估。每马头鱼尾的怪兽被划分成三部分,角 ammonis (CA ) ,有牙齿的回转,和 subicular 建筑群,然后六个基于种子的海马趾的分区网络被建立。六个网络的纵的变化直接随着时间的过去在 rLOD 和控制组之间被比较。从基线到后续,在左 CA 的连接给更大的衰落看到双边的以后的 cingulate cortex/precuneus (PCC/PCUN ) ,但是出现的 rLOD 组与正面的外皮(双边的中间的前额的 cortex/anterior cingulate 外皮和增补马达区域) 增加了恰好海马趾的分区网络的连接。进一步的关联词分析表明在在左 CA 和 PCC/PCUN 之间的 FC 的纵的变化断然在标志位形式测试与纵的变化被相关( r = 0.624 , P = 0.017 )并且位跨度测试( r = 0.545 , P = 0.044 )在 rLOD 组得分。这些结果可以提供卓见进在 rLOD 病人位于认知机能障碍下面的 neurobiological 机制。 | Zan Wang Yonggui Yuan Feng Bai Hao Shu Jiayong You Lingjiang Li Zhijun Zhang | 2015 | Neuroscience Bulletin2015，31，1： | 4 |
| 6 | A novel intelligent verification platform based on a structured analysis model显示文摘An intelligent verification platform based on a structured analysis model is presented.Using an abstract model mechanism with specific signal interfaces for user callback,the unified structured analysis data,shared by the electronic system level design,functional verification,and performance evaluation,enables efficient management review,auto-generation of code,and modeling in the transaction level.We introduce the class tree,flow parameter diagram,structured flow chart,and event-driven finite state machine as structured analysis models.As a sand table to carry maps from different perspectives and levels via an engine,this highly reusable platform provides the mapping topology to search for unintended consequences and the graph theory for comprehensive coverage and smart test cases.Experimental results show that the engine generates efficient test sequences,with a sharp increase in coverage for the same vector count compared with a random test. | XIE Zheng WANG XinAn LIAN ZhiBin LUO YongGui HU ZiYi | 2013 | Science China(Information Sciences)2013，56，6： | 4 |
| 7 | Efficacy and safety of anlotinib plus S-1as thirdly-line or later-line treatmentin advanced non-small cell lung cancer显示文摘Objective Anlotinib,an oral vascular endothelial growth factor receptor 2(VEGFR2)inhibitor,has confirmed antitumor activity in lung cancer in both in vitro and in vivo assays,and has been recommended as third-line treatment agent in non-oncogene driven non-small cell lung cancer(NSCLC).This prospective study aimed to investigate the efficacy and safety of anlotinib plus S-1 for third-or later-line treatment in patients with advanced NSCLC.Methods Patients with histologically or cytologically confirmed NSCLC,and documented disease progression following second-line chemotherapy,and/or epidermal growth factor receptor-tyrosine kinase inhibitor(EGFR-TKI)treatment were enrolled in this study.The patients were treated anlotinib(8 mg daily d 1–14)and S-1(60 mg/m^2 d 1–14)and the treatment was repeated every 3 weeks.Treatment was continued until disease progression or unacceptable toxicity occurred.The objective response rate(ORR),disease control rate(DCR),progression-free survival(PFS),and adverse events(AEs)were reviewed and evaluated.Results Forty-one patients were enrolled in the study between June 2018 and December 2018.The total ORR and DCR were 26.8%and 80.5%,respectively.The median PFS was 5.2 months[95%confidence interval(CI),3.9 to 6.6 months].In the univariate analysis,there was a significant difference in the median PFS between patients with brain metastases and those without brain metastases(4.8 months vs 5.9 months,respectively;P=0.039).The Eastern Cooperative Oncology Group(ECOG)performance status(P=0.002),lines of therapy(P=0.015),and therapeutic evaluation(P=0.014)were independent factors that influenced PFS.The most common AEs were hypertension,proteinuria,myelosuppression,gastrointestinal reactions,fatigue,and mucositis.Conclusion Anlotinib plus S-1 is an effective and safe regimen for advanced NSCLC as third-or later-line therapy. | Heng Cao Kai Liang Peng Liu Jing Wang Yuanyuan Ji Lujuan Xu Weilong Wu Shengnan Guo Xuekun Song Yonggui Hong | 2020 | Oncology and Translational Medicine2020，6，1： | 4 |
| 8 | The constituents of core competencies and firm performance: evidence from high-technology firms in china显示文摘 | Yonggui Wang Hing-Po Lo Yongheng Yang | 2004 | Journal of Engineering and Technology Management2004，，4： | 1 |
| 9 | Growth of cubic KTa1-x Nbx O3 crystal by czochralski method显示文摘 | Wang Xuping Wang J iyang Yu Yonggui | 2006 | Journal of Crystal Growth2006，293，： | 1 |
| 10 | Effects of dams on water and sediment delivery to the sea by the Huanghe (Yellow River): The special role of Water-Sediment Modulation显示文摘 | Yu Yonggui Shi Xuefa Wang Houjie Yue Chengkun Chen Shenliang Liu Yanguang Hu Limin Qiao Shuqing | 2014 | Anthropocene2014，，： | 1 |
| 11 | Customer RelationshipManagement Capabilities:Measurement, Antecedents andConsequences显示文摘 | Yonggui Wang Hui Feng | 2012 | Management Decision2012，，1： | 1 |
| 12 | Forcefrequency coefficient of symmetrical incomplete circular quartz crystal resonator显示文摘 | WANG Zheyao ZHU Huizhong DONG Yonggui | 2001 | IEEE Trans on Ultrason Ferroelectr and Freq Control2001，48，5： | 1 |
| 13 | The constituents of core competence and firm performance显示文摘 | Wang Yonggui LO H P | 2004 | Journal of Engineering and Technology Management2004，，6： | 1 |
| 14 | New discharge regime of the Huanghe(Yellow River):Causes and inplications显示文摘 | YU Yonggui WANG Houjie SHI Xuefa | 2013 | Continental Shelf Research2013，69，2013： | 1 |
| 15 | An Integrated Framework for Customer Value and Customer-relationship-management Performance: A Customer-based Perspective from China 显示文摘 | Wang Yonggui Hing Po Lo Renyong Chi Yongheng Yang | 2004 | Managing Service Quality2004，14，23： | 1 |
| 16 | Growth and thermal properties of YbVO4 single crystal显示文摘 | Yu Yonggui Cheng Yan Zhang Huaijin Wang Jiyang Cheng Xiufeng Xia Hairui | 2006 | Materials Letters2006，60，： | 1 |
| 17 | An integrated framework for customer value and customer-relationship management performance:a customer-based perspective from China显示文摘 | Yonggui Wang Lo Hing Po Chi Renyong Yang Yongheng | | 0，，2： | 1 |
| 18 | Robust po- lyazobenzene microcapsules with photoresponsive pore channels and tunable release profiles显示文摘 | WANG Xiaotao YANG Yingkui LIAO Yonggui | 2012 | European Polymer Journal2012，48，： | 1 |
| 19 | Early Warning of Heavy Metal Pollution after Tailing Pond Failure Accident显示文摘Heavy metal pollution is a major issue after tailing pond failure accident.It is important to predict pollution trends for limited data of pollution sources.A simple phase separation heavy metal model was built for early warning simulation of heavy metal pollution accidents.Based on this,a new simulation framework has been developed to predict the pollution trends of the downstream according to the measured data at upstream sections.By setting the upstream monitoring date as the inflow boundary condition,the changing processes of heavy metal manganese(Mn) with different phases in the downstream can be accurately simulated and forecasted.Results showed that the concentration of the suspended phase in the downstream was larger than that in the aqueous phase and sediment phase.With this,the early warning of pollution trends after accidents could be made a few days ahead.It indicates that the impact of sediment on heavy metal should not be ignored in the early warning of tailing pond failure accidents. | Yonggui Wang Yinqun Yang Qiang Li Yaxin Zhang Xiaolong Chen | 2022 | Journal of Earth Science2022，33，4： | 1 |
| 20 | An integrated framework for customer value and customer - relation- ship - management performance: a customer - based perspective from China显示文摘 | Yonggui Wang Hing Polo Renyong Chi | 2004 | Managing Service Quality2004，14，23： | 1 |
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