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| 1 | Variations in zonal fruit starch concentrations of apples – a developmental phenomenon or an indication of ripening?显示文摘Patterns of starch hydrolysis in stem,equatorial,and calyx zones of‘Honeycrisp’and‘Empire’apples(Malus sylvestris(L.)Mill var.domestica(Borkh.)Mansf.)during maturation and ripening,and in‘Gala’apples in response to propylene or 1-methylcyclopropene(1-MCP)treatments after harvest,were studied.Differences in zonal starch concentrations were found for‘Empire’and‘Gala’fruits,but not for‘Honeycrisp’.During maturation and ripening of‘Empire’,the concentration of starch was highest in the calyx end and lowest in the stem region.Differences in rates of starch hydrolysis among zones were not detected.‘Honeycrisp’and‘Empire’had the highest concentration of sorbitol in the calyx region,whereas it was highest in the stem-end region in‘Gala’.The distribution differences of glucose,fructose,and sucrose were similar in all three cultivars;higher fructose and glucose concentrations in the stem region,and higher sucrose concentrations in the calyx end of the fruit.Postharvest treatment of‘Gala’with propylene did not affect the internal ethylene concentration of the fruit but 1-MCP markedly inhibited it.Starch concentrations were highest in the calyx end but gradients of starch among zones were not changed by postharvest treatment.The rate of hydrolysis was slowed by 1-MCP treatment,but was unaffected by propylene.Postharvest treatments influenced sorbitol,glucose,and fructose concentrations.Patterns of starch concentration among the zones did not confirm differences in ripening,but reflected its uneven distribution throughout the fruit during development.Therefore,measured differences in zonal starch are most likely related to starch accumulation during fruit development,rather than differences in rates of starch degradation during ripening. | Franziska C Doerflinger William B Miller Jacqueline F Nock Christopher B Watkins | 2015 | Horticulture Research2015,2,1: | 3 |
| 2 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017,25,9: | 2 |
| 3 | Spin hamiltonian of Co2+显示文摘 | Ham F S Ludwig G M Watkins G D | 1960 | Phys Rev Lett1960,5,: | 2 |
| 4 | The pain of being sick:implications of immune-to-brain communication for understanding pain 显示文摘 | Watkins L R Maier S F | 2000 | Annu Rev Psychol2000,,51: | 1 |
| 5 | Effects of oxygen stress on tobacco discoloration显示文摘 | Watkins R W Hassler F J | 1962 | Tobacco Science1962,,: | 1 |
| 6 | Glia: a novel drug discovery target for clinical pain 显示文摘 | Watkins L R Maier S F | 2003 | Nat Rev Drug Discov2003,2,12: | 1 |
| 7 | Glial activa- tion and pathological pain 显示文摘 | Wieseler-Frank J Maier S F Watkins L R | 2004 | Neurochem Int2004,45,23: | 1 |
| 8 | Modeling of liquefied petroleum gas Spray development,evaporation and combustion显示文摘 | Watkins A P | 2004 | Int J Engine Res2004,5,6: | 1 |
| 9 | Remifentanil as an analgesic adjunct in local regional anesthesia and in monitored anesthesia care显示文摘 | Servin F Desmonts JM Watkins WD | 1999 | Anesth Analy1999,89,4: | 1 |
| 10 | Physical and mechanical changes in strawberry fruit after high carbondioxide treatments显示文摘 | Harker F R Elgar H J Watkins C B | 2000 | Postharvest Biology and Technology2000,19,2: | 1 |
| 11 | Physical and mechanical changes in strawberry fruit after high carbondioxide treatments显示文摘 | HARKER F R ELGAR H J WATKINS C B | 2000 | Postharvest Biology and Technology2000,19,2: | 1 |
| 12 | Vasopressin: a new target for the treatment of heart failure显示文摘 | Craig R Lee Michael L Watkins J.Herbert Patterson Wendy Gattis Christopher M O'Connor Mihai Gheorghiade Kirkwood F Adams | 2003 | American Heart Journal2003,,1: | 1 |
| 13 | Li-CaO catalysed tri-glyceride transesterification for biodiesel applications 显示文摘 | WATKINS R S LEE A F WILSON K | 2004 | Green Chemistry2004,6,7: | 1 |
| 14 | Rapid 1-methylcyclopropene (1-MCP) treatmen and delayed controlled atmosphere storage of apples显示文摘 | Watkins C B Nock J F | 2012 | Postharvest Biolog and Technology2012,69,: | 1 |
| 15 | Effects of delays between harvest and I-methylcyclopropene treatment,temperature during treatment,onripening air-stored and controlled-atmosphere-stored apples显示文摘 | WATKINS C B NOCK J F | 2005 | HortScience2005,40,: | 1 |
| 16 | Beyond neurons : evidence that immune and glial cells contribute to pathological pain states显示文摘 | Watkins L R Maier S F | 2002 | Physiol Rev2002,82,4: | 1 |
| 17 | Glial activation:a driving force for pathological pain显示文摘 | Watkins L R Milligan E D Maier S F | 2001 | Trends Neurosci2001,24,8: | 1 |
| 18 | Glial activation: adriving force for pathological pain显示文摘 | WATKINS L R MILLIGAN E D MAIER S F | 2001 | Trends Neurosci2001,24,8: | 1 |
| 19 | Elderly migration and development in small communities显示文摘 | Rowles G D Watkins J F | 1993 | Growth and Change1993,24,4: | 1 |
| 20 | Cue deprecia- tion: when word fragment completion is undermined by prior exposure to lesser fragments显示文摘 | PEYNIRCIOGLU Z F WATKINS M J | 1986 | Journal of Experi- mental Psychology : Learning Memory and Cognition1986,12,3: | 1 |