维普中文期刊产品整合服务
83篇 您的检索式:作者名="WeiHan"
    题名 作者 年代 出处 被引量
15-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages显示文摘5-Hydroxymethylcytosine (5hmC ) 是被连接了到基因规定和癌症致病的重要哺乳动物的 DNA epigenetic 修正。这里,我们用定序途径的一枝敏感化学基于标签的低输入的猎枪在传播没有房间的 DNA (cfDNA ) 探索了 5hmC 的诊断潜力。我们从七种不同癌症类型的 49 个病人定序没有房间的 5hmC 并且发现了能被用来与高精确性预言癌症类型和阶段的不同特征。明确地,我们发现肺癌症在 cfDNA 导致 5hmC 的进步全球损失,而 hepatocellular 癌和胰腺的癌症在没有房间的 hydroxymethylome 导致疾病特定的变化。我们的 proof-of-principle 结果建议没有房间的 5hmC 签名可以潜在地被使用不仅识别癌症类型而且在一些癌症追踪肿瘤舞台。Chun-Xiao Song Senlin Yin Li Ma Amanda Wheeler Yu Chen Yan Zhang Bin Liu Junjie Xiong Weihan Zhang Jiankun Hu Zongguang Zhou Biao Dong Zhiqi Tian Stefanie S Jeffrey Mei-Sze Chua Samuel So Weimin Li Yuquan Wei Jiajie Diao Dan Xie Stephen R Quake 2017Cell Research2017,27,10:17
2Expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis显示文摘AIM: To determine the expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis and its clinical significance. METHODS: A cervical spondylosis model was established in rats by destroying the stability of cervical posterior column,and the cord segments C4-6 and gastric antrum were collected 3, 4 and 5 mo after the operation. Rats with sham operation were used as controls. c-fos neuronal counter-staining was performed with an immunohistochemistry method. Every third sections from C4-6 segments were drawn. The 10 most labeled c-fos-immunoreactive (Fos-IR) neurons were counted, and the average number was used for statistical analysis. The mean of Fos-IR neurons in myenteric plexus was calculated after counting Fos-IR neurons in 25 ganglia from each antral preparation, and expressed as a mean count per myenteric ganglion.RESULTS: There were a few c-fos-positive neurons in the cervical cord and antrum in the control group. There was an increased c-fos expression in model group 3, 4 and 5 mo after operation, whereas there was no significant increase in c-fos expression in the control group at 3, 4 and 5 mo.More importantly, there was a significant difference in c-fos expression between rats followed up for 3 mo and those for 5 mo in the model group (11.20±2.26 vs 27.68±4.36,P<0.05, for the cervical cord; and 11.3±2.3 vs 29.3±4.6,P<0.05, for the gastric antrum). There was no significant difference between rats followed up for 3 mo and those for 4 mo and between rats followed up for 4 mo and those for 5 mo in the model group.CONCLUSION: c-fos expression in gastric myenteric plexus was dramatically associated with that in the spinal cord in rats with cervical spondylosis, suggesting that the gastrointestinal function may be affected by cervical spondylosis. If this hypothesis is confirmed by further studies, functional gastrointestinal diseases such as functional dyspepsia and irritable bowel syndrome could be explained by neurogastroenterology.Pei-SongSong Kang-MeiKongx Kang-MeiKong Chun-YanNiu Wei-LiQi Ling-FeiWu Xin-jiaWang WeiHan KengHuang Ze-FengChen 2005World Journal of Gastroenterology2005,11,4:10
3Comparison of survival outcomes between transthoracic and transabdominal surgical approaches in patients with Siewert-Ⅱ/Ⅲesophagogastric junction adenocarcinoma:a single-institution retrospective cohort study显示文摘Objective: To compare the survival outcomes of transabdominal(TA) and transthoracic(TT) surgical approaches in patients with Siewert-Ⅱ/Ⅲ esophagogastric junction adenocarcinoma.Methods: This retrospective study was conducted in patients with Siewert-Ⅱ/Ⅲ esophagogastric junction adenocarcinoma who underwent either TT or TA operations in the West China Hospital between January 2006 and December 2009.Results: A total of 308 patients(109 in the TT and 199 in the TA groups) were included in this study with a follow-up rate of 87.3%. The median(P25, P75) number of harvested perigastric lymph nodes was 8(5, 10) in the TT group and 23(16, 34) in the TA group(P<0.001), and the number of positive perigastric lymph nodes was 2(0, 5) in the TT group and 3(1, 8) in the TA group(P<0.004). The 5-year overall survival(OS) rate was 36% in the TT group and 51% in the TA group(P=0.005). Subgroup analysis by Siewert classification showed that 5-year OS rates for patients with Siewert Ⅱ tumors were 38% and 48% in TT and TA groups, respectively(P=0.134), whereas the 5-year OS rate for patients with Siewert Ⅲ tumors was significantly lower in the TT group than that in the TA group(33% vs. 53%; P=0.010). Multivariate analysis indicated that N2 and N3 stages, R1/R2 resection and a TT surgical approach were prognostic factors for poor OS.Conclusions: Improved perigastric lymph node dissection may be the main reason for better survival outcomes observed with a TA gastrectomy approach than with TT gastrectomy for Siewert Ⅲ tumor patients.Weihan Zhang Xinzu Chen Kai Liu Kun Yang Xiaolong Chen Ying Zhao Yongfan Zhao Jiaping Chen Longqi Chen Jiankun Hu 2016Chinese Journal of Cancer Research2016,28,4:10
4Xuefuzhuyu decoction for hyperlipidemia: a systematic review and Meta-analysis of randomized clinical trails显示文摘OBJECTIVE:To evaluate the efficacy and safety of Xuefuzhuyu decoction for hyperlipidemia.METHODS:Randomized clinical trials on hyperlipidemia treated by Xuefuzhuyu decoction,either alone or with Western Medicine,were searched in electronic databases.Databases searched were:MEDLINE,Allied and Complementary Medicine Database,EMBASE,The Cochrane Library 2013(Issue4),China National Knowledge Infrastructure Database,Chinese Biomedical Literature Database,and Wanfang Database up to 2 May,2013.Study selection,data extraction,quality assessment,and data analysis were conducted according to the Cochranestandards.RESULTS:Six randomized clinical trials involving748 patients(373 patients in the treatment group,375 patients in the control group)were included in the analysis.The studies were of low methodological quality.Meta-analysis indicated that the effect of Xuefuzhuyu decoction on hyperlipidemia was better than that in the control group[n=748,OR=5.07,95%CI(3.40,7.58),P<0.01].Weighted mean differencesin total cholesterol,low-densitylipoprotein cholesterol,triglycerides,and high-density lipoprotein cholesterol were﹣0.79,﹣0.74,﹣0.44,0.16,respectively,and Meta-analysis revealed that the treatment group was better than the control group with 95%CI(﹣1.21,﹣0.36),(﹣0.94,﹣0.55),(﹣0.77,﹣0.11),(0.04,0.27),respectively(all P<0.05).Some adverse events in evaluated studies wererecorded.CONCLUSION:Xuefuzhuyu decoction may be effective for treating hyperlipidemia.The studies we analyzed were of low methodological quality,which indicates that the above findings should be considered cautiously.Therefore,more strictly designed large-scale randomized clinical trials are needed to evaluate the efficacy of Xuefuzhuyu decoction in hyperlipidemia.Jiangquan Liao Jiaxing Tian Tengfei Li Weijiang Song Weihan Zhao Jinhang Du 2014Journal of Traditional Chinese Medicine2014,34,4:5
5Internal short circuit evaluation and corresponding failure mode analysis for lithium-ion batteries显示文摘Internal short circuit(ISC)is the major failure problem for the safe application of lithium-ion batteries,especially for the batteries with high energy density.However,how to quantify the hazard aroused by the ISC,and what kinds of ISC will lead to thermal runaway are still unclear.This paper investigates the thermal-electrical coupled behaviors of ISC,using batteries with Li(Ni_(1/3)CO_(1/3)Mn_(1/3))O_(2) cathode and composite separator.The electrochemical impedance spectroscopy of customized battery that has no LiPF6 salt is utilized to standardize the resistance of ISC.Furthermore,this paper compares the thermal-electrical coupled behaviors of the above four types of ISC at different states-of-charge.There is an area expansion phenomenon for the aluminum-anode type of ISC.The expansion effect of the failure area directly links to the melting and collapse of separator,and plays an important role in further evolution of thermal runaway.This work provides guidance to the development of the ISC models,detection algorithms,and correlated countermeasures.Lishuo Liu Xuning Feng Christiane Rahe Weihan Li Languang Lu Xiangming He Dirk Uwe Sauer Minggao Ouyang 2021Journal of Energy Chemistry2021,30,10:5
6Unraveling a genetic roadmap for improved taste in the domesticated apple显示文摘Although taste is an important aspect of fruit quality, an understanding of its genetic control remains elusive in apple and other fruit crops. In this study, we conducted genomic sequence analysis of 497 Malus accessions and revealed erosion of genetic diversity caused by apple breeding and possible independent domestication events of dessert and cider apples. Signatures of selection for fruit acidity and size, but not for fruit sugar content, were detected during the processes of both domestication and improvement. Furthermore, we found that single mutations in major genes affecting fruit taste, including Ma1, MdTDT, and MdSOT2, dramatically decrease malate, citrate, and sorbitol accumulation, respectively, and correspond to important domestication events. Interestingly, Ma1 was identified to have pleiotropic effects on both organic acid content and sugar:acid ratio, suggesting that it plays a vital role in determining fruit taste. Fruit taste is unlikely to have been negatively affected by linkage drag associated with selection for larger fruit that resulted from the pyramiding of multiple genes with minor effects on fruit size. Collectively, our study provides new insights into the genetic basis of fruit quality and its evolutionary roadmap during apple domestication, pinpointing several candidate genes for genetic manipulation of fruit taste in apple.Liao Liao Weihan Zhang Bo Zhang Ting Fang Xiao-Fei Wang Yarning Cai Collins Ogutu Lei Gao Gang Chen Xiaoqing Nie Jinsheng Xu Quanyan Zhang Yiran Ren Jianqiang Yu Chukun Wang Cecilia H.Deng Baiquan Ma Beibei Zheng Chun-Xiang You Da-Gang Hu Richard Espley Kui Lin-Wang Jia-Long Yao Andrew C.Allan Awais Khan Schuyler S.Korban Zhangjun Fei Ray Ming Yu-Jin Hao Li Li Yuepeng Han 2021Molecular Plant2021,14,9:5
7Nonlinear health evaluation for lithium-ion battery within full-lifespan显示文摘Lithium-ion batteries(LIBs), as the first choice for green batteries, have been widely used in energy storage, electric vehicles, 3C devices, and other related fields, and will have greater application prospects in the future. However, one of the obstacles hindering the future development of battery technology is how to accurately evaluate and monitor battery health, which affects the entire lifespan of battery use. It is not enough to assess battery health comprehensively through the state of health(SoH) alone, especially when nonlinear aging occurs in onboard applications. Here, for the first time, we propose a brand-new health evaluation indicator—state of nonlinear aging(SoNA) to explain the nonlinear aging phenomenon that occurs during the battery use, and also design a knee-point identification method and two SoNA quantitative methods. We apply our health evaluation indicator to build a complete LIB full-lifespan grading evaluation system and a ground-to-cloud service framework, which integrates multi-scenario data collection, multi-dimensional data-based grading evaluation, and cloud management functions. Our works fill the gap in the LIBs’ health evaluation of nonlinear aging, which is of great significance for the health and safety evaluation of LIBs in the field of echelon utilization such as vehicles and energy storage. In addition, this comprehensive evaluation system and service framework are expected to be extended to other battery material systems other than LIBs, yet guiding the design of new energy ecosystem.Heze You Jiangong Zhu Xueyuan Wang Bo Jiang Hao Sun Xinhua Liu Xuezhe Wei Guangshuai Han Shicong Ding Hanqing Yu Weihan Li Dirk Uwe Sauer Haifeng Dai 2022Journal of Energy Chemistry2022,31,9:4
8Recombinant scFv Antibodies against E Protein and N Protein of Severe Acute Respiratory Syndrome Virus显示文摘Three single chain antibodies (scFv) against the proteins of severe acute respiratory syndrome coronavirus (SARS-CoV) were isolated by phage display from an scFv antibody library. Bio-panning was carried out against immobilized purified envelope (E) and nucleocapsid (N) proteins of SARS-CoV. Their binding activity and specificity to E or N protein of SARS-CoV were characterized by phage-ELISA. Two of them, B10 and C20, could recognize non-overlapping epitopes of the E protein according to the two-site binding test result. Clone A17 could recognize N protein. The sequence of the epitope or overlapping epitope of scFv antibody A17 was PTDSTDNNQNGGRNGARPKQRRPQ. The affinity (equilibrium dissociation constant, Kd) of SARS-CoV E protein was 5.7×10–8 M for B10 and 8.9×10–8 M for C20. The affinity of A17 for N protein was 2.1×10–6 M. All three scFv antibodies were purified with affinity chromatography and determined by Western blot.HuiLIU Yan-LiDING WeiHAN Mei-YunLIU Rui-YangTIAN Sheng-LiYANG YiGONG 2004Acta Biochimica et Biophysica Sinica2004,36,8:3
9Coordination Insertion Mechanism of Ring-Opening Polymerization of Lactide Catalyzed by Stannous Octoate显示文摘Main observation and conclusion Ring-opening polymerization(ROP)of cyclic esters in the presence of stannous octoate(Sn(Oct)2)is the main way to obtain biodegradable aliphatic polyesters,an important family of biodegradable polymers which have been widely used and still rapidly developed in the fields of biomedical polymers and environment-friendly materials.Weihan Rao Caiyun Cai Jingyu Tang Yiman Wei Caiyun Gao Lin Yu Jiandong Ding 2021Chinese Journal of Chemistry2021,39,7:2
10Effect of boron addition on the MoO_3/CeO_2–Al_2O_3 catalyst in the sulfur-resistant methanation显示文摘The effect of boron on the performance of MoO_3/CeO_2–Al_2O_3 catalysts, which were prepared with impregnation method, was investigated. The catalysts were characterized with N_2 adsorption–desorption, XRD, H_2-TPR, and NH_3-TPD, and were tested in sulfur-resistant methanation. The results indicated that the MoO_3/CeO_2–Al_2O_3 catalysts modified by boron showed higher catalytic performance in sulfur-resistant methanation. The CO conversion increased from 47% to 62% with 0.5 wt% boron content. When the content of boron was under 0.5 wt%, the results suggested there was an increase in the amorphous form of MoO_3 caused by the generation of weak and intermediate acid sites, which had weakened the interaction between the active components and supports. While, the catalyst added 2.0 wt% boron showed the strong acid sites and the largest crystalline size resulting in the uneven distribution of ceria.Baowei Wang Wenxia Yu Weihan Wang Zhenhua Li Yan Xu Xinbin Ma 2018Chinese Journal of Chemical Engineering2018,26,3:2
11A novel coating technology for fast sealing of air leakage in underground coal mines显示文摘Air leakage in underground coal mines presents a serious hazard for coal production and the safety of miners.Coating technology is commonly used as an efficient means for preventing air leakage.To address existing problems with high dust concentrations in large operations involving complex processes and the high cost of traditional coating technology,a novel coating technology that ensures intrinsic safety by utilizing water pressure and wind pressure was developed.This new coating technology was designed to suction and spray,and the technical parameters of its spray performance was also studied.The experimental tests and evaluation indicated the optimum working range is 0.3–0.7 MPa of wind pressure,1.2–10.2 L/min of water quantity,and 1.0–3.5 m of spraying distance.Moreover,this novel coating technology was tested in the Dashuitou Coal Mine in Gansu Province of China.Compared with conventional counterparts,the proposed new technology is safe,efficient,and convenient to operate.During spraying,dust concentrations were kept at less than 10 mg/m3,and the average rebound ratio resilient rate of solid materials was below 13%.After spraying,the average leakage every 100 m was 4 m3/min,and the oxygen volume fraction in the adjacent goaf was approximately 4%,demonstrating excellent air leakage prevention.Sihua Shao Chunlei Wu Min Hao Xiaolin Song Xueyou Su Weihan Wang Guosheng Li Bobo Shi 2021International Journal of Mining Science and Technology2021,31,2:2
12Superoxide production and reactive oxygen species signaling by endothelial nitric-oxide synthase 显示文摘 Shuibang Wang Liang Yan 2000J Biol Chem2000,275,16:1
13Critical Speeds of Electric Vehicles for Regenerative Braking显示文摘Efficient regenerative braking of electric vehicles(EVs)can enhance the efficiency of an energy storage system(ESS)and reduce the system cost.To ensure swift braking energy recovery,it is paramount to know the upper limit of the regenerative energy during braking.Therefore,this paper,based on 14 typical urban driving cycles,proposes the concept and principle of confidence interval of“probability event”and“likelihood energy”proportion of braking.The critical speeds of EVs for braking energy recovery are defined and studied through case studies.First,high-probability critical braking speed and high-energy critical braking speed are obtained,compared,and analyzed,according to statistical analysis and calculations of the braking randomness and likelihood energy in the urban driving cycles of EVs.Subsequently,a new optimized ESS concept is proposed under the frame of a battery/ultra-capacitor(UC)hybrid energy storage system(HESS)combined with two critical speeds.The battery/UC HESS with 9 UCs can achieve better regenerative braking performances and discharging performances,which indicates that a minimal amount of UCs can be used as auxiliary power source to optimize the ESS.After that,the efficiency regenerative braking model,including the longitudinal dynamics,motor,drivetrain,tire,and wheel slip models,is established.Finally,parameters optimization and performance verification of the optimized HESS are implemented and analyzed using a specific EV.Research results emphasize the significance of the critical speeds of EVs for regenerative braking.Xianxu Bai Gen Chen Weihan Li Rui Jia Liang Xuan Anding Zhu Jingchang Wang 2021Automotive Innovation2021,4,2:1
14Effects of parasitic plant Cistanche deserticola on chlorophyll a fluorescence and nutrient accumulation of host plant Haloxylon ammodendron in the Taklimakan Desert显示文摘The parasitic plant Cistanche deserticola attaches to Haloxylon ammodendron, a perennial shrub with high tolerance to salinity and drought. However, little was known about the parasite-host relation between the two species. Effects of the parasite on chlorophyll a fluorescence and nutrient accumulation in the host plant (H. ammodendron) were investigated in the Taklimakan Desert. Some photosynthetic parameters of both host and non-host H. ammodendron plants were measured by in vivo chlorophyll a fluorescence technology in the field. The assimilating branches of host and non-host plants were collected and nutrient and inorganic ion contents were analyzed. The results from field experiments showed that the infection of C. deserticola reduced the non-photochemical quenching of the variable chlorophyll fluorescence (NPQ) and the potential maximum quantum yield for primary photochemistry (F v /F m ) of the host. Compared with non-host plants, the host H. ammodendron had low nutrient, low inorganic ion contents (Na + and K + ) and low K + /Na + ratios in the assimilating branches. It suggested that C. deserticola infection reduced the nutrient acquisition and caused damage to the photoprotection through thermal dissipation of the energy of the photosystem II in the host, resulting in a decrease in the tolerance to salinity and high radiation. It was concluded that the attachment of the parasite plant (C. deserticola) had negative effects on the growth of its host.Li LI XinWen XU YongQiang SUN WeiHAN PengFei TU 2012Journal of Arid Land2012,4,3:1
15Novel Method for Preparing a Carbon Nanotube-Supported Cobalt Catalyst for Fischer–Tropsch Synthesis:Hydrogen Dielectric-Barrier Discharge Plasma显示文摘Hydrogen dielectric-barrier discharge(H_2-DBD)plasma was successfully used to prepare carbon nanotubes(CNTs)-supported cobalt(Co) catalyst.The H_2-DBD plasma treatment simultaneously decomposed and reduced the cobalt precursor at a lower temperature and in a shorter time than the conventional method(calcination and hydrogen reduction).It is considered that the H_2-DBD plasma method can remarkably decrease the amount of energy input compared to traditional methods used to prepare the Co-based catalyst in Fischer-Tropsch synthesis(FTS).Results showed that the Co catalyst prepared by H_2-DBD plasma had an equivalent catalytic performance for FTS as that prepared using the conventional method in calcination and hydrogen reduction,thereby determining that H_2-DBD plasma was an effective alternative treatment for preparing the Co/CNTs catalyst for FTS.This technology will provide a new strategy for preparing catalysts in other catalysis processes.Zhenhua Li Runxue Liu Renjie Liu Weihan Wang Jing Lv 2017Transactions of Tianjin University2017,23,1:1
16An hp adaptive strategy for finite element approximations of the navier-stokes equations 显示文摘J Tinsley Oden Weihan Wu Vincent Legat 1995International Journal for Numerical Methods in Fluids1995,20,89:1
17Effects of CeO2 preparation methods on the catalytic performance of MoO3/CeO2 toward sulfur-resistant methanation显示文摘CeO_2 supports were prepared by calcination or precipitation method and 5% MoO_3/CeO_2 catalysts were prepared by incipient-wetness impregnation method. The catalytic performance of the 5% MoO_3/CeO_2 catalysts toward sulfur-resistant methanation was investigated. The results showed that the Mo/Ce-1 catalysts with CeO_2 support prepared by calcination method exhibited the best sulfur-resistant methanation activity and stability with CO conversion as high as 75% while the Mo/Ce-3 catalysts the poorest. The supports and catalysts were characterized by N_2-adsorption–desorption, temperature-programmed reduction(TPR), X-ray diffraction(XRD), Raman spectroscopy(RS) and scanning electron microscope(SEM). The results indicated that the saturated monolayer loading MoO_3 on Ce-3 support was lower than 5% and there were some crystalline MoO_3 particles on the surface of the Mo/Ce-3. The preparation method of CeO_2 had a big influence on the specific surface area, the crystalline of CeO_2, and the catalytic performance of the corresponding Mo-based catalyst for sulfur-resistant methanation.Dajun Meng Baowei Wang Zhen Liu Weihan Wang Zhenhua Li Xinbin Ma 2017Journal of Energy Chemistry2017,26,3:1
18The role of atmospheric aerosol composition in climate change显示文摘The chemical composition of atmospheric aerosols has been investigated. Contributions ofsulfate and soot in aerosols to the atmospheric extinction are studied. Discussions are made on the problems of aerosol emitted from volcano, forest fires in northern China, 1987 and oil field fires in Kuwait, 1991. It is indicated that the changes in concentration, particle size, and chemical composition of aerosol after those events could have impacts on the climate change either regionally or globally and that the impact of aerosol particles on climate change could compensate for some temperature increase caused by greenhouse gases and the increase of surface intensity of ultraviolet radiation due to ozone layer depletion.Su Weihan Wang ShaobinResearch Center for Eco- Environmental Sciences, Chinese Academy of Sciences Beijing 100085, China 1993Journal of Environmental Sciences1993,5,2:1
19A Genetic Approach for Coordinate Transformation Test of GPS Positioning 显示文摘Chihung W Hungju C Weihan S 2007Geoscience and Remote Sensing Letters IEEE2007,4,2:1
20Sulfur-resistant methanation over MoO_3/CeO_2–ZrO_2 catalyst: Influence of Ce-addition methods显示文摘In this paper, Ce_(0.2)Zr_(0.8)O_2 composite supports were prepared by different Ce-addition methods including impregnation of cerium(CeZr-imp), impregnation of citric acid and cerium(CeZr-CA) simultaneously and deposition precipitation method(CeZr-DP), respectively. The as-prepared supports were applied to prepare 10 wt% MoO_3/Ce_(0.2)Zr_(0.8)O_2 catalysts for sulfur-resistant methanation. The N_2 adsorption/desorption,X-ray diffraction(XRD), Raman spectroscopy(RS), X-ray photoelectron(XPS), temperature-programmed reduction by hydrogen(H_2-TPR) were undertaken to get textural properties, morphological information and structures of the catalysts. The results showed that Mo O_3 was highly dispersed on the surface of these three supports and Ce was mostly of coexisted in Ce^(4+)/Ce^(3+) redox pairs. Compared with Mo/CeZrimp, the CO conversion increased by 10% and 15% for Mo/CeZr-CA and Mo/CeZr-DP, respectively. This was mainly attributed to the larger specific surface area, Ce^(3+) concentration and content of active MoS_2 on the surface of catalysts.Zhaopeng Liu Yan Xu Zhenhua Li Baowei Wang Weihan Wang Xinbin Ma Renjie Liu 2019Journal of Energy Chemistry2019,28,1:1
返回顶部 每页显示:
共5页 首页 上一页 第1页 下一页 末页 /5 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费