|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Petrogenesis of Mesozoic granitoids and volcanic rocks in South China: A response to tectonic evolution显示文摘 | Xinmin Zhou Tao Sun Weizhou Shen Liangshu Shu Yaoling Niu | 2006 | Episodes2006，29，1： | 645 |
| 2 | Strongly peraluminous granites of Mesozoic in Eastern Nanling Range, southern China: Petrogenesis and implications for tectonics显示文摘The strongly peraluminous granites (SPGs) of Eastern Nanling Range (ENR) are a characteristic of all bearing highly aluminous minerals, such as muscovite±Al-rich biotite±tourmaline±garnet, and lack of cordierite. In respect of petrography, geochemistry, Nd isotope, and single grain zircon U-Pb dating, the representative granite bodies of them are studied. The research shows that these granites were emplaced in two stages, namely 228-225 Ma BP and J2-3 159-156 Ma BP, belonging to Indosinian and early Yanshanian periods, respectively, and they have low εNd(t) values (-10.6--11.1), high A/CNK, Rb/Sr ratios and tDM values (1887-1817 Ma), and REE's tetrad effect (TE1, 3=1.13-1.34). In comparison with related geology, petrology and chronology of granites in adjacent regions, it is suggested that Indosinian SPGs of ENR formed in the circumstance of post-collisional extension 20 Ma after the major collision of Indosinian Movement (258-243 Ma BP) in Indo-China Peninsula, and early Yanshanian SPGs formed in the background of back-arc extension setting controlled by paleo-Pacific tectonic domain, and J1, the interval of two stages, is the interim from Tethyan to Pacific tectonic domains in South China. These SPGs have similar geological and geochemical characteristics, because they all crystallized from the magma of partial melting of early Proterozoic metasedimentary rocks when the thickened crust (≤50 km) became thinning, decompression, and transmitting of water. | SUN Tao, ZHOU Xinmin, CHEN Peirong, LI Huimin, ZHOU Hongying, WANG Zhicheng & SHEN Weizhou Department of Earth Sciences, Nanjing University, Nanjing 210093, China Tianjin Institute of Geology and Mineral Resources, China Geological Survey, Tianjin 300170, China | 2005 | Science China Earth Sciences2005，48，2： | 78 |
| 3 | nflammasomes in cancer: a double-edgecl sword显示文摘 | Ryan Kolb Guang-Hui Liu Ann M. Janowski Fayyaz S. Sutterwala Weizhou Zhang | 2014 | Protein & Cell2014，5，1： | 34 |
| 4 | SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2显示文摘 | Huize Pan Di Guan Xiaomeng Liu Jingyi Li Lixia Wang Jun Wu Junzhi Zhou Weizhou Zhang Ruotong Ren Weiqi Zhang Ying Li Jiping Yang Ying Hao Tingting Yuan Guohong Yuan Hu Wang Zhenyu Ju Zhiyong Mao Jian Li Jing Qu FuchouTang Guang-Hui Liu | 2016 | Cell Research2016，26，2： | 32 |
| 5 | SHRIMP zircon U-Pb ages and tectonic implications for Indosinian granitoids of southern Zhuguangshan granitic composite, South China显示文摘The large southern Zhuguangshan granitic batholith composite consists of granites with ages varying from the Caledonian through Indosinian to Yanshanian. Based on K-Ar dating data, the ages of the major parts of this composite were previously regarded as Yanshanian. In this study, the SHRIMP zircon U-Pb dating method has been adopted for six plutons, Ledong, Longhuashan, Dawozi, Zhaidi, Baiyun and Jiangnan, in the southern Zhuguangshan composite, in which the four plutons other than Baiyun and Jiangnan were previously regarded as Yanshanian granites. Magmatic zircons from these six plutons, dated by this study, have yielded ages of 239±5 Ma (MSWD = 2.5), 239±5 Ma (MSWD = 2.5), 239±2 Ma (MSWD = 1.7), 239±4 Ma (MSWD = 3.2), 231±2 Ma (MSWD = 0.81) and 231±3 Ma (MSWD = 1.8), respectively. The results indicate that these plutons were formed by early Indosinian magmatism. Geochemical characteristics suggest that these granites were formed in an extensional tectonic environment. Therefore, the Indosinian period granites in the southern Zhuguangshan composite were formed by partial melting of the Paleo-Mesoproterozoic crustal components during the collapse of thickened lithosphere after the collision between the South China and Indosinian plates. | DENG Ping REN JiShun LING HongFei SHEN WeiZhou SUN LiQiang ZHU Ba TAN ZhengZhong | 2012 | Chinese Science Bulletin2012，57，13： | 19 |
| 6 | Therapeutic polypeptides based on HBcAg_(18-27) CTL epitope can induce antigen-specific CD_8^+ CTL-mediated cytotoxicity in HLA-A2 transgenic mice显示文摘To explore how to bigger an HLAI-restricted CD8+ T cellresponse to exogenously synthesized polypeptides in vivo. | Tong-DongShi Yu-ZhangWu Zheng-CaiJia WeiZhou Li-YunZou | 2004 | World Journal of Gastroenterology2004，10，8： | 17 |
| 7 | Degradation of Nitrobenzene-Containing Wastewater with O_3 and H_2O_2 by High Gravity Technology显示文摘Nitrobenzene-containing industrial wastewater was degraded in the presence of ozonecoupled with H2O2 by high gravity technology. The effect of high gravity factor, H2O2 concentration, pH value, liquid flow-rate, and reaction time on the efficiency for removal of nitrobenzene was investigated. The experimental results show that the high gravity technology enhances the ozone utilization efficiency with O3 /H2O2 showing synergistic effect. The degradation efficiency in terms of the COD removal rate and nitrobenzene removal rate reached 45.8% and 50.4%, respectively, under the following reaction conditions, viz.: a high gravity factor of 66.54, a pH value of 9, a H2O2 /O3 molar ratio of 1:1, a liquid flow rate of 140L/h, an ozone concentration of 40mg/L, a H2O2 multiple dosing mode of 6mL/h, and a reaction time of 4h. Compared with the performance of conventional stirred aeration mixers, the high gravity technology could increase the COD and nitrobenzene removal rate related with the nitrobenzene-containing wastewater by 22.9% and 23.3%, respectively. | Jiao Weizhou Liu Youzhi Liu Wenli Li Jing Shao Fan Wang Chaoran | 2013 | China Petroleum Processing & Petrochemical Technology2013，15，1： | 16 |
| 8 | Geochemical Characteristics and Genesis of the Luxi-Xianrenzhang Diabase Dikes in Xiazhuang Uranium Orefield, Northern Guangdong Province显示文摘The Luxi-Xianrenzhang diabase dikes were emplaced into the eastern part of the Guidong composite granitoids in northern Guangdong Province at the end of the Early Cretaceous. They show tholeiitic features, enrichment in large ion lithophile elements, slight enrichment in light rare earth elements, depletion in Zr and Hf, and basically no depletion in Nb and Ta and no Eu anomaly. They are similar to intraplate basalt in terms of trace element characteristics. They have high εNd(t) values (3.6–4.9), initial 87Sr/86Sr ratios (0.70530–0.70641) and δ18O values and Dupal anomaly of Pb isotope compositions. Their Sr-Nd, Pb-Sr, Pb-Nd and Pb-Pb isotopes plot between DMM and EMII, with Pb similar to EMII, Nd relatively close to DMM and Sr in between. This profile suggests that the diabase dikes studied were derived from partial melting of a mantle source that had been subjected to metasomatism by fluids originated from a subduction zone under a tectonic environment of crustal extension and lithosphere thinning in the late Yanshanian. | LING Hongfei SHEN Weizhou DENG Ping JIANG Shaoyong JIANG Yaohui YE Haimin PU Wei TAN Zhengzhong | 2005 | Acta Geologica Sinica(English Edition)2005，79，4： | 13 |
| 9 | Therapeutic polypeptides based on HBV core 18-27 epitope can induce CD_8^+ CTL-mediated cytotoxicity in HLA-A2^+ human PBMCs显示文摘AIM: To explore how to improve the immunogenicity of HBcAg CTL epitope based polypeptides and to trigger an HBV-specific HLA I-restricted CD8^+ T cell response in vitro.METHODS: A new panel of mimetic therapeutic peptides based on the immunodominant B cell epitope of HBV PreS2 18-24 region, the CTL epitope of HBcAg18-27 and the universal T helper epitope of tetanus toxoid (TT) 830-843 was designed using computerized molecular design method and synthesized by Merrifield's solid-phase peptide synthesis.Their immunological properties of stimulating activation and proliferation of lymphocytes, of inducing TN1 polarization,CD8^+ T cell magnification and HBV-specific CD8^+ CTL mediated cytotoxicity were investigated in vitro using HLA-A2^+ human peripheral blood mononuclear cells (PBMCs) from healthy donors and chronic hepatitis B patients.RESULTS: Results demonstrated that the therapeutic polypeptides based on immunodominant HBcAg18-27 CTL,PreS2 B- and universal TN epitopes could stimulate the activation and proliferation of lymphocytes, induce specifically and effectively CD8+ T cell expansion and vigorous HBVspecific CTL-mediated cytotoxicity in human PBMCs.CONCLUSION: It indicated that the introduction of immunodominant T helper plus B-epitopes with short and flexible linkers could dramatically improve the immunogenicity of short CTL epitopes in vitro. | Tong-DongShi Yu-ZhangWu Zheng-CaiJia Li-YunZou WeiZhou | 2004 | World Journal of Gastroenterology2004，10，13： | 13 |
| 10 | ROR1, an embryonic protein with an emerging role in cancer biology显示文摘(ROR1 ) 受体酷氨酸象 kinase 一样孤儿受体 1 是由 ROR1 和 ROR2 组成的 ROR 家庭的一个成员。ROR 包含二个不同细胞外的充满半胱氨酸的领域和领域 transmembrane 领域。在细胞内部的部分以内, ROR1 拥有一个酷氨酸 kinase 领域,二个 serine/threonine-rich 领域和一个充满脯氨酸的领域。ROR 通过许多相当或相同的事物在胚胎的 patterning 和神经发生的上下文被学习了。这些生理的函数基于 kinase 域的要求是两分的。成长文学为癌症作为一个标记建立了 ROR1,例如在 CLL 和另外的血恶意。另外, ROR1 极其涉及很多血和稳固的恶意的前进。ROR1 被显示了禁止 apoptosis,加强 EGFR 发信号,并且导致上皮间充质的转变(EMT ) 。重要地, ROR1 在胚胎的织物仅仅是可检测的并且通常在成年织物不在,使蛋白质成为为癌症治疗的一个理想的药目标。 | Nicholas Borcherding David Kusner Guang-Hui Liu Weizhou Zhang | 2014 | Protein & Cell2014，5，7： | 12 |
| 11 | Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding显示文摘 | Jiping Yang Jingyi Li Keiichiro Suzuki Xiaomeng Liu Jun Wu Weiqi Zhang Ruotong Ren Weizhou Zhang Piu Chan Juan Carlos Izpisua Belmonte Jing Qu Fuchou Tang Guang-Hui Liu | 2017 | Cell Research2017，27，9： | 12 |
| 12 | Degradation of Wastewater Containing Nitrobenzene by High Gravity-Ultrasonic/Ozonation/Electrolysis Technology显示文摘The integrated high gravity-ultrasonic/ozonation/electrolysis technology was applied in the pretreatment of wastewater containing nitrobenzene.The effect of pH value,high gravity factor,liquid flow-rate and electric current density on removal of COD and nitrobenzene compounds was investigated.Experimental results have determined the optimal process regime involving a high gravity factor of 100,an electric current density of 20mA/cm2,a liquid flow-rate of 100L/h,and an initial liquid pH value of 11.After the wastewater had been treated for 180 min,the degradation of nitrobenzene and COD reached 99% and 80%,respectively,with the biochemical coefficient(BOD/COD) equating to 0.64,and the subsequent treatment of wastewater could be carried out by conventional biochemical means.Compared with traditional aerationozone contactors,a rotating packed bed with high mass transfer characteristics could be used to increase the ozonation treatment efficiency. | Jiao Weizhou Liu Youzhi Shao Fan Liu Wenli Li Jing Wang Chaoran | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，3： | 11 |
| 13 | Vitamin C alleviates aging defects in a stem cell model for Werner syndrome显示文摘沃纳症候群(WS ) 是主要影响从中层导出的纸巾的早衰混乱。我们最近用 WRN 缺乏的人的间充质的干细胞(MSC ) 开发了一个新奇人的 WS 模型。这个模型概括 WS 的许多 phenotypic 特征。基于很多化学药品的一幅屏幕,这里,我们发现维生素 C 在出现在WRN缺乏的 MSC 的早衰为许多特征施加很有效的营救包括细胞生长拘捕,增加了反应的氧种层次, telomere 摩擦,煽动性的因素的过多的分泌物,象原子薄板和 heterochromatin 的组织的破坏一样。而且,维生素 C 在一个老鼠模型在 vivo 恢复 MSC 的生存能力。定序分析的 RNA 显示维生素 C 改变涉及染色质冷凝作用,房间周期规定, DNA 复制,和 DNA 损坏的一系列基因的表示在 WRN 缺乏的 MSC 的修理小径。我们的结果为 WS MSC 作为一个恢复因素识别维生素 C,它保持作为 WS 的处理的一种新奇类型被使用的潜力。 | Ying Li Weizhou Zhang Liang Chang Yan Han Liang Sun Xiaojun Gong Hong Tang Zunpeng Liu Huichao Deng Yanxia Ye Yu Wang Jian Li Jie Qiao Jing Qu Weiqi Zhang Guang-Hui Liu | 2016 | Protein & Cell2016，7，7： | 10 |
| 14 | The thermal history of the miarolitic granite at Xincun, Fujian Province, China显示文摘The thermal history of the late Mesozoic miarolitic granite has been studied based on zircon U-Pb dating, whole rock Rb-Sr dating and K-Ar dating of muscovite, biotite and K-feldspar from the same rock sample. From the beginning of zircon crystallization to the closure of K-Ar system of biotite, the granite body had a slow cooling rate (11.0℃/Ma) and an ascending rate (0.07 mm/a). From the end of this stage to the closure of K-Ar system of K-feldspar, the granite body increased its cooling rate (45℃/Ma) and ascending rate (0.36 mm/a). The thermal history of the Xincun granite with a slow cooling rate at the early stage and a fast cooling rate at the late stage may have been related to the fact that the Fujian coastal area had very high geothermal gradient in the late Mesozoic and evident decrease in geothermal gradient in the early Cenozoic. | SHEN Weizhou LING Hongfei LI Huimin LI Wuxian WANG Dezi | 2000 | Chinese Science Bulletin2000，45，21： | 9 |
| 15 | Find and replace: editing human genome in pluripotent stem cells显示文摘Genetic manipulation of human pluripotent stem cells(hPSCs)provides a powerful tool for modeling diseases and developing future medicine.Recently a number of independent genome-editing techniques were developed,including plasmid,bacterial artificial chromosome,adeno-associated virus vector,zinc finger nuclease,transcription activator-like effecter nuclease,and helper-dependent adenoviral vector.Gene editing has been successfully employed in different aspects of stem cell research such as gene correction,mutation knock-in,and establishment of reporter cell lines(Raya et al.,2009;Howden et al.,2011;Li et al.,2011;Liu et al.,2011b;Papapetrou et al.,2011;Sebastiano et al.,2011;Soldner et al.,2011;Zou et al.,2011a).These techniques combined with the utility of hPSCs will significantly influence the area of regenerative medicine. | Huize Pan Weiqi Zhang Weizhou Zhang Guang-Hui Liu | 2011 | Protein & Cell2011，2，12： | 6 |
| 16 | Degradation and mineralization of aniline by O_3/Fenton process enhanced using high-gravity technology显示文摘The degradation and mineralization of aniline(AN) using ozone combined with Fenton reagent(O_3/Fenton) in a rotating packed bed(RPB) was proposed in this study, and the process(RPB-O_3/Fenton) was compared with conventional O_3/Fenton in a stirred tank reactor(STR-O_3/Fenton) or single ozonation in an RPB(RPB-O_3). Effects of high gravity factor, H_2O_2 dosage, H_2O_2 dosing method and initial p H on the AN mineralization efficiency were investigated in the RPB-O_3/Fenton process. In addition, the behavior of Fe(II) was monitored at different H2 O2 dosing methods and p H values. Finally, the optimal operation conditions were determined with high gravity factor of100, initial pH of 5, Fe(II) concentration of 0.8 mmol·L^(-1) and H_2O_2 dosage of 2.5 ml. Under these conditions, for aniline wastewater at the volume of 1 L and concentration of 200 mg·L^(-1), a fast and thorough decay of AN was conducted in 10 min, and the TOC removal efficiency reached 89% in 60 min. The main intermediates of p-benzoquinone, nitrobenzene, maleic acid and oxalic acid were identified by liquid chromatography/mass spectroscopy(LC/MS), and the degradation pathways of AN in RPB-O_3/Fenton system were proposed based on experimental evidence. It could be envisioned that high-gravity technology combined with O_3/Fenton processes would be promising in the rapid and efficient mineralization of wastewater. | Yuejiao Qin Shuai Luo Shuo Geng Weizhou Jiao Youzhi Liu | 2018 | Chinese Journal of Chemical Engineering2018，26，7： | 6 |
| 17 | Isotopic Geochronology of the Xianghongdian Alkaline Complex, Northern Margin of the Dabie Mountains, China显示文摘To the north of the Qinling-Dabie orogen there exists a Mesozoic (K1) granite-syenite belt called the Beihuaiyang granite-syenite belt, in which the Xianghongdian alkaline complex outcrops in the Devonian Foziling schist and also intruded into the slightly earlier volcanic rocks. This alkaline complex is composed of syenite, alkaline syenite and nepheline syenite, but the nepheline syenite occurs inside the alkaline syenite in the pod-like, irregular, lenticular or layered shape. Researches on the petrogenesis of the alkaline complex and the relationship between the alkaline syenite and the nepheline syenite must rely on precise isotopic ages. Previous researches have reported iso-topic dating results merely by the 40Ar/39Ar method on hornblende and biotite separated from the alkaline syenite and nepheline syenite. In view of this, the authors have made fairly detailed isotopic geochronological studies of the alkaline syenite and nepheline syenite by using Rb-Sr isochron for the whole rock and minerals, | YANG Zhuliang SHEN Weizhou SHEN Jialin TAO Kuiyuan XIE Fanggui | 1999 | Acta Geologica Sinica(English Edition)1999，73，4： | 6 |
| 18 | Applications of high-gravity technologies in gas purifications: A review显示文摘The traditional gas purification techniques such as wet gas desulfurization, with their advantages of large-scale implementation and maturity, have still been widely used. However, the main drawback of these techniques is the low transfer efficiency, which normally needs towers as tall as tens of meters to remove the pollutants. Therefore, new technologies which could enhance the mass transfer efficiency and are less energy-intensive are highly desirable. As a process intensification technology, high-gravity technology, which is carried out in a rotating packed bed(RPB), has recently demonstrated great potential for industrial applications due to its high mass transfer efficiency, energy-saving, and smaller volume. This consequently provides higher efficiency in toxic gas removal, and can significantly reduce the investment and operation costs. In this review, the mechanism,characteristics, recent developments, and the industry applications of high-gravity technologies in gas purifications, such as hydrogen sulfide, nitrogen oxide, carbon dioxide, sulfur dioxide, volatile organic compounds and nanoparticle removal are discussed, most of the demonstration projects and practical application examples in gas purification come from China. The perspective and prospective of this technology in gas purification and other fields are also briefly discussed. | Jing Guo Weizhou Jiao Guisheng Qi Zhiguo Yuan Youzhi Liu | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 5 |
| 19 | Sr, Nd and O Isotopic Studies on the Genesis of the Huashan Granite Complex显示文摘Systematical Sr, Nd and O isotopic studies were made on the Huashan granite complex in Guangxi. Incombination with the studies of geological, petrological and geochemical data, it is believed that the complexconsists of granites of three stages. with different geneses and different source materials. They are not the prod-ucts of differentiation and evolution of one single consanguineous magma. Granites of the 1st stage are of theIndosinian syntectic type or I type, also derived from a mixed mantle-crustal source. Those of the 2nd stage areof the early Yanshanian syntectic type or I type. also derived from a mixed mantle-crustal source, and those ofthe 3rd stage are of the late Yanshanian transformed type or S type. derived from a crustal source. | Zhu Jinchu Li Xiangdong Shen Weizhou Wang Yinxi Yang Jiedong Department of Earth Sciences, Nanjing University, Nanjing, Jiangsu Department of Materials Analysis, Nanjing University, Nanjing, Jiangsu Jia Zhongpeng | 1990 | Acta Geologica Sinica(English Edition)1990，64，1： | 5 |
| 20 | Study on Industrial Application of Hydrogen Sulfide Removal by Wet Oxidation Method with High Gravity Technology显示文摘The removal of hydrogen sulfide from gas plays an important role in rational utilization of resources and environ- mental protection. In this paper, the process of hydrogen sulfide removal by wet oxidation method in a rotating packed bed was investigated in a scale for treating 10 000 Nm3/h of gas. On the basis of studying the influence of the species and con- centration of alkali source, the liquid/gas volume ratio, the high gravity factor, and the hydrogen sulfide content in feed gas on the desulfurization effect, the suitable technological conditions were obtained. The hydrogen sulfide removal efficiency could reach 98.0% under these conditions. The results of continuous operation of process facilities showed that the high gravity method has many merits including higher desulfurization rate, good stability in operation, lower liquid/gas volume ratio, greater operation elasticity, and apparent energy saving effects. | Qi Guisheng Liu Youzhi Jiao Weizhou (Research Center of Shanxi Province for High Gravity Chemical Engineering and Technology, North University of China, Taiyuan 030051) | 2011 | China Petroleum Processing & Petrochemical Technology2011，13，4： | 5 |
您所在的机构暂未开通此部分的功能，请联系管理员