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21篇 您的检索式:作者名="Wen Cun"
    题名 作者 年代 出处 被引量
1Determination of urinary 8-hydroxy-2′-deoxyguanosine by capillary electrophoresis with molecularly imprinted monolith in-tube solid phase microextraction显示文摘Urinary 8-hydroxy-2'-deoxyguanosine(8-OHdG) is an excellent marker of oxidative DNA damage.In this study,employing guanosine as dummy template a novel molecularly imprinted(MIP) monolithic capillary column had been synthesized,and that was used as medium of in-tube solid phase microextraction(SPME).Coupled with capillary electrophoresis-electrochemical detection(CE-ECD),the system of extraction and detection of 8-OHdG in urinary sample had been developed.Because of its greater phase ratio combined with c...Zhang, Shao Wen Zou, Cun Jie Luo, Nan Weng, Qian Feng Cai, Ling Shuang Wu, Cai Ying Xing, Jun 2010Chinese Chemical Letters2010,21,1:6
2Alterations of brain local functional connectivity in amnestic mild cognitive impairment显示文摘Background:Resting-state functional magnetic resonance imaging studies using a regional homogeneity(ReHo)method have reported that amnestic mild cognitive impairment(aMCI)was associated with abnormalities in local functional connectivity.However,their results were not conclusive.Methods:Seed-based d Mapping was used to conduct a coordinate-based meta-analysis to identify consistent ReHo alterations in aMCI.Results:We identified 10 studies with 11 datasets suitable for inclusion,including 378 patients with aMCI and 435 healthy controls.This meta-analysis identified significant ReHo alterations in patients with aMCI relative to healthy controls,mainly within the default mode network(DMN)(bilateral posterior cingulate cortex[PCC],right angular gyrus,bilateral middle temporal gyri,and left parahippocampal gyrus/hippocampus),executive control network(right superior parietal lobule and dorsolateral prefrontal cortex),visual network(right lingual gyrus and left middle occipital gyrus),and sensorimotor network(right paracentral lobule/supplementary motor area,right postcentral gyrus and left posterior insula).Significant heterogeneity of ReHo alterations in the bilateral PCC,left parahippocampal gyrus/hippocampus,and right superior parietal lobule/angular gyrus was observed.Exploratory meta-regression analyses indicated that general cognitive function,gender distribution,age,and education level partially contributed to this heterogeneity.Conclusions:This study provides provisional evidence that aMCI is associated with abnormal ReHo within the DMN,executive control network,visual network,and sensorimotor network.These local functional connectivity alterations suggest coexistence of functional deficits and compensation in these networks.These findings contribute to the modeling of brain functional connectomes and to a better understanding of the neural substrates of aMCI.Confounding factors merit much attention and warrant future investigations.Dan Zheng Wei Xia Zhong Quan Yi Pan Wen Zhao Jian Guo Zhong Hai Cun Shi Hua Liang Li Zhen Yu Dai Ping Lei Pan 2018Translational Neurodegeneration2018,7,1:5
3A new phenanthraquinone from the roots of Peucedanum praeruptorum显示文摘新混合物, 9,10-dihydrophenanthrinic 酸, 9,10-dione-3,4-methylenedioxy-8-methoxy (1 ) 从 Peucedanum praeruptorum Dunn 的根被孤立根据光谱证据。Cun Zhang Li Li Yong Qing Xiao Wen Li Xiao Jie Yin Guo Fang Tian Dong Dong Chen Yun Wang 2010Chinese Chemical Letters2010,21,7:4
4Synthesis of N-methylene phosphonic chitosan(NMPCS)and its potential as gene carder显示文摘N-Methylene phosphoulc chitosan (NMPCS),an amphiphilic macromolecule with powerful chelating ability of Ca^(2+) ions,was synthesized and characterized.The physicochemical properties of NMPCS and the interactions between NMPCS and plasmid DNA were investigated by FTIR,^(13)C NMR,X-ray,agarose gel electrophorcsis retardation assay,atomic force microscopy (AFM) and circular dichroism (CD).The results suggest that at charge ratio 2:1 or above,DNA could be completely entrapped and spherical complexes with mean size of 80-210 nm were formed.Taking HeLa as host cell,luciferase expression mediated by NMPCS improved about 100 times compared to the expression mediated by chitosan.Dun Wan Zhu Jin Gen Bo Hai Ling Zhang Wen Guang Liu Xi Gang Leng Cun Xian Song Yu Ji Yin Li Ping Song Lan Xia Liu Lin Mei Xiu Lan Li Yang Zhang Kang De Yao 2007Chinese Chemical Letters2007,18,11:3
5Using capillary electrophoresis mobility shift assay to study the interaction of CdTe quantum dots with bovine serum albumin显示文摘在这个工作,毛状的电气泳动活动性移动试金(CEMSA ) 首先被采用与量点(QD ) 学习蛋白质的相互作用。在这研究,牛的浆液白朊(BSA ) 和 CdTe QD 被用作模型样品。我们观察到 BSA 轻易地被吸附到 CdTe QD 表面,和 QD 鈥揃S 建筑群被 1:1 stoichiometric 比率形成。2.17 卤的价值 0.27 脳 106 摩尔 ? 1 L ? 1 (在 25 掳 C ) 为协会,常数被 CEMSA 获得。Li Wen Shao Chao Qing Dong Xiang Yi Huang Ji Cun Ren 2008Chinese Chemical Letters2008,19,6:2
6Effect of weak acid catalysts on trans - esterification of soybean oil in supercritical methanol 显示文摘Wang Cun Wen Zhou Jun Feng Chen Wen 2008Energy & Fuel2008,22,:1
7Synthesis of the rare earth compound nanosheets induced by lamellar liquid crystal显示文摘Cun Wen Yi Liu Yun Guo Yanqin Wang Guanzhong Lu 2009Solid State Sciences2009,,:1
8Rolling penetrate descriptor for shape-based image retrieval and object recognition 显示文摘Yun Wen Chen Cun Lu Xu 2009Pattern Recognition Letters2009,30,9:1
9Impacts of Water Consumption Structure Adjustment on Social-Economic Development and Water Cycle显示文摘Chun Feng Hao Yang Wen Jia Cun Wen Niu Cheng Zhu 2014Advanced Materials Research2014,,962:1
10Development of a rapid UPLC‐MS/MS method for quantification of saxagliptin in rat plasma and application to pharmacokinetic study显示文摘Jing‐wen Gao Yue‐mei Yuan Ya‐song Lu Mei‐cun Yao 2012Biomed Chromatogr2012,,12:1
11Expression of a cytotoxic cationic antibacterial peptide in Escherichia coli using two fusion partners显示文摘Yu Qing Chen Shuang Quan Zhang Bao Cun Li Wen Qiu Bo Jiao Jie Zhang Zhen Yu Diao 2007Protein Expression and Purification2007,,2:1
12Safe food, green food, good food: Chinese Community Supported Agriculture and the rising middle class 显示文摘Yan Shi Cun~ ang Cheng Peng Lei Tiejun Wen & Caroline Merrifield 2011International Journal of Agricultural Sustainability2011,9,4:1
13Water gas shift reaction on metal nanoclusters encapsulated in me- soporous ceria studied with ambient - pressure X - ray photoelectron spectroscopy 显示文摘Wen Cun Zhu Yuan Ye Yingchun 2012ACS Nano2012,6,10:1
14Effect of Weak Acids as a Catalyst on the Transesterification of Soybean Oil in Supercritical Methanol显示文摘Wang Cun Wen Zhou Jun Feng 2008Energy and Fuels2008,22,:1
15COSINE:A web server for clonal and subclonal structure inference and evolution in cancer genomics显示文摘Cancer cell genomes originate from single-cell mutation with sequential clonal and subclonal expansion of somatic mutation acquisition during pathogenesis,thus exhibiting a Darwinian evolutionary process(Gerstung et al.,2020;Nik-Zainal et al.,2012).Through next-generation sequencing of tumor tissue,this evolutionary process can be characterized by statistical modelling,which can identify the clonal state,somatic mutation order,and evolutionary process(Gerstung et al.,2020;Mcgranahan&Swanton,2017).Inference of clonal and subclonal structure from bulk or single-cell tumor genomic sequencing data has a huge impact on studying cancer evolution.Clonal state and mutation order can provide detailed insight into tumor origin and future development.In the past decade,various methods for subclonal reconstruction using bulk tumor sequencing data have been developed.However,these methods had different programming languages and data input formats,which limited their use and comparison.Therefore,we established a web server for Clonal and Subclonal Structure Inference and Evolution(COSINE)of cancer genomic data,which incorporated twelve popular subclonal reconstruction methods.We deconstructed each method to provide a detailed workflow of single processing steps with a user-friendly interface.To the best of our knowledge,this is the first web server providing online subclonal inference based on the integration of most popular subclonal reconstruction methods.COSINE is freely accessible at www.clab-cosine.net.Xi-Guo Yuan Yuan Zhao Yang Guo Lin-Mei Ge Wei Liu Shi-Yu Wen Qi Li Zhang-Bo Wan Pei-Na Zheng Tao Guo Zhi-Da Li Martin Peifer Yu-Peng Cun 2022Zoological Research2022,43,1:0
16Correction to:Alterations of brain local functional connectivity in amnestic mild cognitive impairment显示文摘Correction to:Transl Neurodegener http://gffzzd3cc09b8251d45dfsp9ubv0xqqp0o60uk.ffgz.tsg.suse.edu.cn/10.1186/s40035-018-0134-8 In the original publication of this article[1]surname of the first author is wrong.The correct name of the first author should be Dan Zheng.The original publication has been corrected.Dan Zheng Wei Xia Zhong Quan Yi Pan Wen Zhao Jian Guo Zhong Hai Cun Shi Hua Liang Li Zhen Yu Dai Ping Lei Pan 2018Translational Neurodegeneration2018,7,1:0
17Radical cation salts induced domino reaction of anilines with enol ethers:Synthesis of 1,2,3,4-tetrahydroquinoline derivatives显示文摘有 TBPA+(5 mol%) 的催化数量导致的周期、非循环的 enol 醚的苯胺的牙齿反应被调查,一系列 2,4-disubstituted-1,2,3,4-tetrahydroquinolines 被综合。与周期的 enol 醚不同当非循环的 enol 醚在反应被使用时,他们用作乙醛的代理人,生产一系列 2-methyl-4-anilino-1,2,3,4-tetrahydroquinolines。单个电子转移机制被建议文饰产品形成。Xiao Dong Jia Yan Ren Cong Dde Huo Wen Juan Wang Xiang Ning Chen Qiong Fu Xi Cun Wang 2011Chinese Chemical Letters2011,22,6:0
18Synthesis of bis-ANS fluorescence probe in ionic liquids显示文摘在荧光探查 5,5 ′ 的准备的离子的液体的新应用; -bis-8-phenylamino-1-naphthylsulfonate (二度 -- ANS ) 被代表。为荧光探查二度的准备的方法 -- 在烷基 imidazolium 猫的 ANS 在酸的条件下面的离子的液体被描述。在钠亚硝酸根和不同离子的液体的不同集中下面的反应收益上的效果被学习,好收益被完成。Wen Lu Liu Fa Qin Jiang Jing Bao Liu Jian Cun Zhang Lei Fu 2009Chinese Chemical Letters2009,20,6:0
19Van Hove Singularities as a Result of Quantum Confinement:The Origin of Intriguing Physical Properties in Pb Thin Films显示文摘In situ angle-resolved photoemission spectroscopy(ARPES)and scanning tunneling spectroscopy(STS)have been used to study the electronic structure of Pb thin films grown on a Si(111)substrates.The experiments reveal that the electronic structure near the Fermi energy is dominated by a set of m-shaped subbands because of strong quantum confinement in the films,and the tops of the m-shaped subbands form an intriguing ring-like Van Hove singularity.Combined with theoretical calculations,we show that it is the Van Hove singularity that leads to an extremely high density of states near the Fermi energy and the recently reported strong oscillations(with a period of two monolayers)in various properties of Pb films.Yu Jie Sun S.Souma Wen Juan Li T.Sato Xie Gang Zhu Guang Wang Xi Chen Xu Cun Ma Qi Kun Xue Jin Feng Jia T.Takahashi T.Sakurai 2010Nano Research2010,3,11:0
20Kinetic comparison between ferric ion and decamethyferrocene at the liquid/liquid interface as studied by scanning electrochemical microscopy显示文摘Comparison in electron transfer(ET) processes from decamethyferrocene(DMFe) in nitrobenzene(NB) to ferric ion in aqueous phase was investigated for the first time by the scanning electrochemical microscopy(SECM).As compared with the system of Fe(CN)_6^(3-)-DMFe,the ET rate obtained from Fe^(3+)-DMFe was lower in spite of larger driving force,which may arise from the effect of reorganization energy.Otherwise,the effect of common ion on rate constants was also probed and results suggested additional comple...Lu, Xiao Quan Ma, Jun Ying Liu, Xiu Hui Dong, Cun Wu Wang, Wen Ting 2010Chinese Chemical Letters2010,21,1:0
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