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| 1 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 2 | Studies on the antioxidative activity of hsian-tsao (Mesona procumbens Hemsl) leaf gum显示文摘 | LAI Lihshiuh CHOU Sutze CHAO Wenwan | 2001 | Journal of Agricultural and Food Chemistry2001，49，2： | 1 |
| 3 | Cyr61 Suppresses Growth of Human Endometrial Cancer Cells 显示文摘 | Wenwan Chien Takashi Kumagai Carl W | 2004 | J Biol Chem2004，279，53： | 1 |
| 4 | Typing of multiple single-nucleotide polymorphisms by a microsphere-based roiling circle amplification assay 显示文摘 | LI Jishan ZHONG Wenwan | 2007 | Analytical Chemistry2007，79，： | 1 |
| 5 | CE combined with rolling circle amplification for sensitive DNA detection 显示文摘 | LI Ni LI Jishan ZHANG Wenwan | 2008 | Electrophoresis2008，29，： | 1 |
| 6 | Prognostic value of mucin 4 expression in colorectal adenocarcinomas显示文摘 | ChandrakumarShanmugam Nirag C.Jhala Venkat R.Katkoori WenWan SreelathaMeleth William E.Grizzle UpenderManne | 2010 | Cancer2010，，15： | 1 |
| 7 | A semiparametric technique for the multi‐response optimization problem显示文摘 | WenWan Jeffrey B.Birch | 2011 | Qual. Reliab. Engng. Int2011，，1： | 1 |
| 8 | Storage and computing resource enabled joint virtual resource allocation with Qo S guarantee in mobile networks显示文摘Virtualization is the trend for the future mobile networks. With the advantage of virtualization,we can abstract the physical mobile network into the virtual network function(VNF) and design the network without the details. In this paper, we focus on the virtualization of the physical resources so that the resource allocation scheme considers not only the time-varying characteristic of wireless channels but also the amount of storage and computing resources. Virtual resources are composed of radio, storage and computing resources based on the virtualization technology. Since the cloud radio access network(C-RAN) is a successful paradigm to introduce computing resources into mobile networks, we investigate the virtual resource allocation scheme in the C-RAN architecture. With the content caching technology, we introduce the storage resources into joint resource allocation scheme further. In order to evaluate the performance of proposed scheme, we choose the effective capacity as the metric to include the influence of service latency. The purpose of the optimization problem is maximizing the system effective capacity with constraints of radio, storage and computing resources.It is simplified and converted into a convex problem solved by the subgradient method. Simulation results are provided to demonstrate performance gain of the effective capacity based joint resource allocation scheme. | Xiaodong XU Jiaxiang LIU Wenwan CHEN Yanzhao HOU Xiaofeng TAO | 2017 | Science China(Information Sciences)2017，60，4： | 0 |
| 9 | RIS-assisted MIMO secure communications with Bob's statistical CSI and without Eve's CSI显示文摘In this paper,we consider a reconfigurable intelligent surface(RIS)-assisted multiple-input multiple-output(MIMO)secure communication system,where only legitimate user's(Bob's)statistical channel state information(CSI)can be obtained at the transmitter(Alice),while eavesdropper's(Eve's)CSI is unknown.Firstly,the analytical expression of the achievable ergodic rate at Bob is obtained.Then,by exploiting Bob's statistical CSI,we jointly design the transmit covariance matrix at Alice and the phase shift matrix at the RIS to minimize the transmit power of the information signal under the quality-of-service(QoS)constraint of Bob.Finally,we propose an artificial noise(AN)-aided method without Eve's CSI to enhance the security of this system and use the residual power to design the transmit covariance for AN.Simulation results verify the convergence of the proposed method,and also show that there exists a trade-off between the secrecy rate and QoS of Bob. | Wenwan Xu Jun Zhang Shu Cai Jue Wang Yi Wu | 2023 | Digital Communications and Networks2023，9，3： | 0 |
| 10 | Real-time observation of frequency Bloch oscillations with fibre loop modulation显示文摘Bloch oscillations(BOs)were initially predicted for electrons in a solid lattice to which a static electric field is applied.The observation of BOs in solids remains challenging due to the collision scattering and barrier tunnelling of electrons.Nevertheless,analogies of electron BOs for photons,acoustic phonons and cold atoms have been experimentally demonstrated in various lattice systems.Recently,BOs in the frequency dimension have been proposed and studied by using an optical micro-resonator,which provides a unique approach to controlling the light frequency.However,the finite resonator lifetime and intrinsic loss hinder the effect from being observed practically.Here,we experimentally demonstrate BOs in a synthetic frequency lattice by employing a fibre-loop circuit with detuned phase modulation.We show that a detuning between the modulation period and the fibre-loop roundtrip time acts as an effective vector potential and hence a constant effective force that can yield BOs in the modulation-induced frequency lattices.With a dispersive Fourier transformation,the pulse spectrum can be mapped into the time dimension,and its transient evolution can be precisely measured.This study offers a promising approach to realising BOs in synthetic dimensions and may find applications in frequency manipulations in optical fibre communication systems. | Hao Chen NingNing Yang Chengzhi Qin Wenwan Li Bing Wang Tianwen Han Chi Zhang Weiwei Liu Kai Wang Hua Long Xinliang Zhang Peixiang Lu | 2021 | Light(Science & Applications)2021，10，3： | 0 |
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