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| 1 | On extended state based Kalman filter design for a class of nonlinear time-varying uncertain systems显示文摘This paper considers the filtering problem for a class of multi-input multi-output systems with nonlinear time-varying uncertain dynamics, random process and measurement noise. An extended state based Kalman filter, with the idea of timely estimating the unknown dynamics, is proposed for better robustness and higher estimation precision. The stability of the proposed filter is rigorously proved for nonlinear timevarying uncertain system with weaker stability condition than the extended Kalman filter, i.e., the initial estimation error, the uncertain dynamics and the noises are only required to be bounded rather than small enough. Moreover, quantitative precision of the proposed filter is theoretically evaluated. The proposed algorithm is proved to be the asymptotic unbiased minimum variance filter for constant uncertainty. The simulation results of some benchmark examples demonstrate the feasibility and effectiveness of the method. | Wenyan BAI Wenchao XUE Yi HUANG Haitao FANG | 2018 | Science China(Information Sciences)2018，61，4： | 7 |
| 2 | The source and transport of bioaerosols in the air:A review显示文摘Recent pandemic outbreak of the corona-virus disease 2019(COVID-19)has raised widespread concerns about the importance of the bioaerosols.They are atmospheric aerosol particles of biological origins,mainly including bacteria,fungi,viruses,pollen,and cell debris.Bioaerosols can exert a substantial impact on ecosystems,climate change,air quality,and public health.Here,we review several relevant topics on bioaerosols,including sampling and detection techniques,characterization,effects on health and air quality,and control methods.However,very few studies have focused on the source apportionment and transport of bioaerosols.The knowledge of the sources and transport pathways of bioaerosols is essential for a comprehensive understanding of the role microorganisms play in the atmosphere and control the spread of epidemic diseases associated with them.Therefore,this review comprehensively summarizes the up to date progress on the source characteristics,source identification,and diffusion and transport process of bioaerosols.We intercompare three types of diffusion and transport models,with a special emphasis on a widely used mathematical model.This review also highlights the main factors affecting the source emission and transport process,such as biogeographic regions,land-use types,and environmental factors.Finally,this review outlines future perspectives on bioaerosols. | Wenwen Xie Yanpeng Li Wenyan Bai Junli Hou Tianfeng Ma Xuelin Zeng Liyuan Zhang Taicheng An | 2021 | Frontiers of Environmental Science & Engineering2021，15，3： | 2 |
| 3 | Green‑Solvent Processed Blade‑Coating Organic Solar Cells with an Efficiency Approaching 19%Enabled by Alkyl‑Tailored Acceptors显示文摘Power-conversion-efficiencies(PCEs)of organic solar cells(OSCs)in laboratory,normally processed by spin-coating technology with toxic halogenated solvents,have reached over 19%.However,there is usually a marked PCE drop when the bladecoating and/or green-solvents toward large-scale printing are used instead,which hampers the practical development of OSCs.Here,a new series of N-alkyl-tailored small molecule acceptors named YR-SeNF with a same molecular main backbone are developed by combining selenium-fused central-core and naphthalene-fused endgroup.Thanks to the N-alkyl engineering,NIR-absorbing YR-SeNF series show different crystallinity,packing patterns,and miscibility with polymeric donor.The studies exhibit that the molecular packing,crystallinity,and vertical distribution of active layer morphologies are well optimized by introducing newly designed guest acceptor associated with tailored N-alkyl chains,providing the improved charge transfer dynamics and stability for the PM6:L8-BO:YRSeNF-based OSCs.As a result,a record-high PCE approaching 19%is achieved in the blade-coating OSCs fabricated from a greensolvent o-xylene with high-boiling point.Notably,ternary OSCs offer robust operating stability under maximum-power-point tracking and well-keep>80%of the initial PCEs for even over 400 h.Our alkyl-tailored guest acceptor strategy provides a unique approach to develop green-solvent and blade-coating processed high-efficiency and operating stable OSCs,which paves a way for industrial development. | Hairui Bai Ruijie Ma Wenyan Su Top Archie Dela Pea Tengfei Li Lingxiao Tang Jie Yang Bin Hu Yilin Wang Zhaozhao Bi Yueling Su Qi Wei Qiang Wu Yuwei Duan Yuxiang Li Jiaying Wu Zicheng Ding Xunfan Liao Yinjuan Huang Chao Gao Guanghao Lu Mingjie Li Weiguo Zhu Gang Li Qunping Fan Wei Ma | 2023 | Nano-Micro Letters2023，15，12： | 1 |
| 4 | Radiolytic decomposition of 4-bromodiphenyl ether显示文摘Polybrominated diphenyl ethers (PBDEs) spread widely in the environment are mainly removed by photochemical and anaerobic microbial degradation. In this paper, the decomposition of 4-bromodiphenyl ether (BDE -3), the PBDEs homologues, is investigated by electron beam irradiation of its ethanol/water solution (reduction system) and acetonitrile/water solution (oxidation system). The radiolytic products were determined by GC coupled with electron capture detector, and the reaction rate constant of esol– in the reduction system was measured at 2.7×1010 L·mol–1·s–1 by pulsed radiolysis. The results show that the BDE-3 concentration affects strongly the decomposition ratio in the alkali solution, and the reduction system has a higher BDE-3 decomposition rate than the oxidation system. This indicates that the BDE-3 was reduced by effectively capturing esol– in radiolytic process. | TANG Liang XU Gang WU Wenjing SHI Wenyan LIU Ning BAI Yulei WU Minghong | 2010 | Nuclear Science and Techniques2010，21，2： | 0 |
| 5 | Genetic Architecture of Childhood Kidney and Urological Diseases in China显示文摘Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary component.To delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration system is being imple-mented based on the Chinese Children Genetic Kidney Disease Database(CCGKDD).In this study,all the patients with kidney and urological diseases were recruited from 2014 to 2020.Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features.The genetic diagnosis was confirmed in 883 of 2256(39.1%)patients from 23 provinces in China.Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome(SRNS,23.5%),glomerulonephritis(GN,32.2%),congenital anomalies of the kidney and urinary tract(CAKUT,21.2%),cystic renal disease(3.9%),renal calcinosis/stone(3.6%),tubulopathy(9.7%),and chronic kidney disease of unknown etiology(CKDu,5.8%).The pathogenic variants of 105 monogenetic disorders were identified.Ten distinct genomic disorders were identified as pathogenic copy number variants(CNVs)in 11 patients.The diagnostic yield differed by subgroups,and was highest in those with cystic renal disease(66.3%),followed by tubulopathy(58.4%),GN(57.7%),CKDu(43.5%),SRNS(29.2%),renal calcinosis/stone(29.3%)and CAKUT(8.6%).Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions.We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed.Our data demonstrate the utility of family-based exome sequencing,and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease. | Ye Fang Hua Shi Tianchao Xiang Jiaojiao Liu Jialu Liu Xiaoshan Tang Xiaoyan Fang Jing Chen Yihui Zhai Qian Shen Guomin Li Li Sun Yunli Bi Xiang Wang Yanyan Qian Bingbing Wu Huijun Wang Wenhao Zhou Duan Ma Jianhua Mao Xiaoyun Jiang Shuzhen Sun Ying Shen Xiaorong Liu Aihua Zhang Xiaowen Wang Wenyan Huang Qiu Li Mo Wang Xiaojie Gao Yubin Wu Fang Deng Ruifeng Zhang Cuihua Liu Li Yu Jieqiu Zhuang Qing Sun Xiqiang Dang Haitao Bai Ying Zhu Siguang Lu Bili Zhang Xiaoshan Shao Xuemei Liu Mei Han Lijun Zhao Yuling Liu Jian Gao Ying Bao Dongfeng Zhang Qingshan Ma Liping Zhao Zhengkun Xia Biao Lu Yulong Wang Mengzhun Zhao Jianjiang Zhang Shan Jian Guohua He Huifeng Zhang Bo Zhao Xiaohua LI Feiyan Wang Yufeng Li Hongtao Zhu Xinhui Luo Jinghai Li Jia Rao Hong Xu | 2021 | Phenomics2021，1，3： | 0 |
| 6 | UGT1A1-related Bilirubin Encephalopathy/Kernicterus in Adults显示文摘Background and Aims:Bilirubin encephalopathy/kernicterus is very rare in adults.This study is aimed to investigate the clinical manifestations and genetic features of two patients with UGT1A1-related kernicterus.Methods:Sanger sequencing analysis was performed to identify UGT1A1 gene mutations in the patients and their families.Bioinformatics analysis was used to predict the potential functional effects of novel missense mutations.Clinical manifestations and biochemical parameters were collected and analyzed.Results:Two patients with Crigler-Najjar syndrome type II(CNS2)developed kernicterus in adulthood.Sanger sequencing identified a compound heterozygous mutation in the UGT1A1 gene in patient 1,which was inherited from his mother(G71R)and his father(c.-3279T>G;S191F).Patient 2 carried three heterozygous mutations,namely G71R,R209W and M391K;among which,the M391K mutation has not been reported before.Multiple prediction software showed that the M391K mutation was pathogenic.Symptoms were relieved in the two patients after phenobarbital and artificial liver support treatment.Patient 1 also underwent liver transplantation.Conclusions:Adults with CNS2 are at risk for kernicterus.Phenobarbital treatment is beneficial for maintaining bilirubin levels and preventing kernicterus. | Jie Bai Lu Li Hui Liu Shuang Liu Li Bai Wenyan Song Yu Chen Sujun Zheng Zhongping Duan | 2021 | Journal of Clinical and Translational Hepatology2021，9，2： | 0 |
| 7 | A HRG novel mutation associated with idiopathic portal hypertension: Case report and literature review显示文摘Idiopathic portal hypertension(IPH)is defined as the presence of portal hypertension in the absence of a common cause.IPH can have several etiologies,one of which is a genetic disorder.Some genetic mutations,such as KCNN3 and DGUOK,were shown to be related to IPH pathogenesis.This is the first case report of a 22-year-old man who was diagnosed with IPH with a novel heterozygous mutation in the histidine-rich glycoprotein gene(c.545G>C,p.R182T).Using bioinformatics analysis and the protein quantification method,we showed that this novel mutation has a pathogenetic role in IPH.Our study broadens the mutation spectrum of the histidine-rich glycoprotein gene and provides new ideas for IPH etiology. | Shan Tang Li Bai Wei Zhang Wenyan Song Hui Liu Lei Li Chen Liang Zhongping Duan Sujun Zheng | 2022 | iLIVER2022，1，2： | 0 |
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