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| 1 | Nitrogen-doped graphene supported Pd@PdO core- shell clusters for C-C coupling reactions显示文摘 | Baojiang Jiang Sanzhao Song Jianqiang Wang Ying Xie Wenyi Chu Hongfeng Li Hui Xu Chungui Tian Honggang Fu | 2014 | Nano Research2014,7,9: | 7 |
| 2 | Role of SKP1-CUL1-F-Box-Protein (SCF) E3 Ubiquitin Ligases in Skin Cancer显示文摘Many biological processes such as cell proliferation, differentiation, and cell death depend precisely on the timely synthesis anddegradation of key regulatory proteins. While protein synthesis can be regulated at multiple levels, protein degradation is mainlycontrolled by the ubiquitineproteasome system (UPS), which consists of two distinct steps: (1) ubiquitylation of targeted protein by E1ubiquitin-activating enzyme, E2 ubiquitin-conjugating enzyme and E3 ubiquitin ligase, and (2) subsequent degradation by the 26Sproteasome. Among all E3 ubiquitin ligases, the SCF (SKP1-CUL1-F-box protein) E3 ligases are the largest family and are responsiblefor the turnover of many key regulatory proteins. Aberrant regulation of SCF E3 ligases is associated with various human diseases, such ascancers, including skin cancer. In this review, we provide a comprehensive overview of all currently published data to define a promotingrole of SCF E3 ligases in the development of skin cancer. The future directions in this area of research are also discussed with an ultimategoal to develop small molecule inhibitors of SCF E3 ligases as a novel approach for the treatment of human skin cancer. Furthermore,altered components or substrates of SCF E3 ligases may also be developed as the biomarkers for early diagnosis or predicting prognosis. | Chuan-Ming Xie Wenyi Wei Yi Sun | 2013 | Journal of Genetics and Genomics2013,40,3: | 6 |
| 3 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016,1,1: | 2 |
| 4 | Specific Responses of Soil Microbial Residue Carbon to Long-Term Mineral Fertilizer Applications to Reddish Paddy Soils显示文摘Mineral nutrient inputs to soil may alter microbial activity and consequently influence the accumulation of microbial residues. In this study, we investigated the effects of application rates and ratios of mineral fertilizers on the microbial residue carbon(MRC) of reddish paddy soils after long-term(15-year) fertilizer applications in southern China. Contents of three soil amino sugars as microbial residue contents were determined and MRC were calculated based on amino sugars. Results showed that three individual amino sugar contents increased as fertilizer application rates increased until maximum values were reached at a rate of 450-59-187 kg ha^(-1) year^(-1)(N-P-K). The three amino sugar contents then declined significantly under the highest mineral fertilizer application rate of 675-88-280 kg ha^(-1) year^(-1)(N-P-K). In addition, to enhance the microbial residue contents, it was more beneficial to double P(N:P:K= 1:0.26:0.41) in fertilizers applied to the P-deficient reddish paddy soils than to double either N(N:P:K = 2:0.13:0.41) or K(N:P:K= 1:0.13:0.82). The contents of the three individual amino sugars and microbial residues under different fertilizer application rates and ratios were significantly and positively correlated with soil organic carbon(SOC), total N, total P, and p H. Increases in values of the fungal C to bacterial C ratios showed that soil organic matter(SOM) stability increased because of the fertilizer applications over the past 15 years. The contents and ratios of amino sugars can be used as indicators to evaluate the impact of mineral fertilizer applications on SOM dynamics in subtropical paddy soils. The results indicated that fertilizer applications at a rate of 450-59-187 kg ha^(-1) year^(-1)(N-P-K) may improve crop yields, SOC contents, and SOC stability in subtropical paddy soils. | ZHANG Xinyu XIE Juan YANG Fengting DONG Wenyi DAI Xiaoqin YANG Yang SUN Xiaomin | 2018 | Pedosphere2018,28,3: | 2 |
| 5 | Systematic analysis of clinical relevance and molecular characterization of m^(6)A in COVID-19 patients显示文摘N6-methyladenosine(m6A)is the most prevalent post-transcriptional RNA modification in mRNA and long non-coding RNAs of eukaryotes,and its biological functions are mediated by m6A writers,erasers and readers.1 A nuclear methyltransferase complex consisting of METTL3,METTL14,WTAP,VIRMA,ZC3H13,RBM15(or RBM15B),YWHAG,TRA2A and CAPRIN1 catalyzes the m6A modifications,acting as m6A writers.1 m6A demethylase ALKBH5 as well as m6A demethylase FTO mediate the demethylation of m6As,acting as the m6A erasers. | Sanqi An Zhouhua Xie Yanyan Liao Junjun Jiang Wenyi Dong Fuqiang Yin Wen-Xing Li Li Ye Jianyan Lin Hao Liang | 2022 | Genes & Diseases2022,9,5: | 1 |
| 6 | Corrigendum to“First demonstration of improving laser propagation inside the spherical hohlraums by using the cylindrical laser entrance hole”[Matter Radiation Extremes 1(1)(2016)2-7]显示文摘Corrigendum Text:On page 2 of this letter,there is a misprint in the unit.The unit of the geometrical dimension of the spherical hohlraums on this page should always be“mm”rather than“mm”,i.e.in the second paragraph,“…with 800 J per beam at 0.35 mm…”should be“…with 800 J per beam at 0.35 mm…”,“The slit of 400 mm width is parallel…”should be“The slit of 400 mm width is parallel…”,“The laser focal diameter is about 500 mm…”should be“The laser focal diameter is about 500 mm…”;in the third paragraph,“…we take 850 mm as the radius…”should be“…we take 850 mm as the radius…”,“The LEH radius R_(L) is 400 mm…”should be“The LEH radius R_(L) is 400 mm…”,“…the radius of the cylindrical LEH outer ring is taken as 1.5 R_(L)=600 mm”should be“…the radius of the cylindrical LEH outer ring is taken as 1.5 R_(L)=600 mm”.This mistake does not affect any of the main results of the original letter. | Wenyi Huo Zhichao Li Dong Yang Ke Lan Jie Liu Guoli Ren Sanwei Li Zhiwen Yang Liang Guo Lifei Hou Xuefei Xie Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Guanghui Yuan Haijun Zhang Baibin Jiang Lizhen Huang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Yongkun Ding Xiantu He Weiyan Zhang | 2016 | Matter and Radiation at Extremes2016,1,2: | 1 |
| 7 | A novel multistage anoxic/aerobic process with sludge regeneration zone (R-MAO) for advanced nitrogen removal from domestic sewage显示文摘To achieve advanced nitrogen removal from actual municipal sewage,a novel multistage anoxic/aerobic process with sludge regeneration zone(R-MAO)was developed.The reactor was used to treat actual domestic sewage and the nitrogen removal capacity of the sludge regeneration zone(R zone)was investigated during the long-term operation.The best performance was obtained at the R zone’s Oxidation-Reduction Potential(ORP)of-50±30 mV and hydraulic residence times(HRT)of 1.2 hr.The average effluent COD,TN,NH_(4)^(+)-N and NO_(3)^(−)-N of the R-MAO process were 18.0±2.3,7.5±0.6,1.0±0.5 and 4.6±0.4 mg/L,respectively,with the corresponding removal efficiency of COD,TN and NH_(4)^(+)-N were 92.9%±1.0%,84.1%±1.5% and 97.5%±1.1%.Compared to the sole MAO system,the TN removal efficiency of the R-MAO increased by 10.1%.Besides,under the optimal conditions,the contribution of the R zone in the R-MAO that removal COD,TN,NH_(4)^(+)-N and NO_(3)^(−)-N were 0.36,0.15,0.032 and 0.82 g/day.High-throughput sequencing results showed that uncultured_bacterium_f_Burkholderiaceae(5.20%),OLB8(1.04%)and Ottowia(1.03%)played an important role in denitrification in the R zone.This study provided effective guidance for the design and operation of the R-MAO process in domestic sewage treatment. | Lin Cao Rong Sun Wenyi Dong Hongjie Wang Zhongyi Dai Xue Wang Jin Xie Hua Li | 2023 | Journal of Environmental Sciences2023,,2: | 1 |
| 8 | Growth of α-LiIO_(3) Single Crystal Grown in Space显示文摘α-LiIO_(3) single crystals were grown by the aqueous solution method in a Chinese scientific return-satellite.The morphology of the crystals grown in space are similar to that of earth-grown crystals.It is found that the growth rates of the positive and negative sides of the space-grown crystals are almost the same.The perfection of both crystals grown in space and on earth was examined. | MAI Zhenhong CHEN Wanchun CUI Shufan MA Wenyi XIE Anyun XU Lu JIN Zecen CHEN Gang | 1991 | Chinese Physics Letters1991,8,4: | 1 |
| 9 | Fabrication and electrochemical treatment application of a microstructured TiO 2 -NTs/Sb–SnO 2 /PbO 2 anode in the degradation of C.I. Reactive Blue 194 (RB 194)显示文摘 | Hao An Hao Cui Wenyi Zhang Jianping Zhai Yan Qian Xianchuan Xie Qin Li | 2012 | Chemical Engineering Journal2012,,: | 1 |
| 10 | Qing Hua Chang Yin exerts therapeutic effects against ulcerative colitisthrough the inhibition of the TLR4/NF?κB pathway显示文摘 | Xiao Ke Fan Zhou Youliang Gao Bingying Xie Guanghong Hu Wenyi Fang Jun Peng Youqin Chen Thomas Sferra | 2013 | International Journal of Molecular Medicine2013,,4: | 1 |
| 11 | Dual-Driven Hemostats Featured with Puncturing Erythrocytes for Severe Bleeding in Complex Wounds显示文摘Achieving rapid hemostasis in complex and deep wounds with secluded hemorrhagic sites is still a challenge because of the difficulty in delivering hemostats to these sites.In this study,a Janus particle,SEC-Fe@CaT with dual-driven forces,bubble-driving,and magnetic field–(MF–)mediated driving,was prepared via in situ loading of Fe_(3)O_(4) on a sunflower sporopollenin exine capsule(SEC),and followed by growth of flower-shaped CaCO3 clusters.The bubble-driving forces enabled SEC-Fe@CaT to self-diffuse in the blood to eliminate agglomeration,and the MF-mediated driving force facilitated the SEC-Fe@CaT countercurrent against blood to access deep bleeding sites in the wounds.During the movement in blood flow,the meteor hammer-like SEC from SEC-Fe@CaT can puncture red blood cells(RBCs)to release procoagulants,thus promoting activation of platelet and rapid hemostasis.Animal tests suggested that SEC-Fe@CaT stopped bleeding in as short as 30 and 45 s in femoral artery and liver hemorrhage models,respectively.In contrast,the similar commercial product Celox™required approximately 70 s to stop the bleeding in both bleeding modes.This study demonstrates a new hemostat platform for rapid hemostasis in deep and complex wounds.It was the first attempt integrating geometric structure of sunflower pollen with dual-driven movement in hemostasis. | Haoyu Qiu Guangqian Lan Weiwei Ding Xinyu Wang Wenyi Wang Dahua Shou Fei Lu Enling Hu Kun Yu Songmin Shang Ruiqi Xie | 2022 | Research2022,,4: | 0 |
| 12 | Elevated CO_(2) increases soil redox potential by promoting root radial oxygen loss in paddy field显示文摘Soil redox potential(Eh)plays an important role in the biogeochemical cycling of soil nutrients.Whereas its effect soil process and nutrients'availability under elevated atmospheric CO_(2) concentration and warming has seldom been investigated.Thus,in this study,a field experiment was used to elucidate the effect of elevated CO_(2) concentration and warming on soil Eh,redox-sensitive elements and root radial oxygen loss(ROL).We hypothesized elevated CO_(2) and warming could alter soil Eh by promoting or inhibiting ROL.We found that soil Eh in the rhizosphere was significantly higher than that of non-rhizosphere.Elevated CO_(2) enhanced soil Eh by 11.5%,which corresponded to a significant decrease in soil Fe^(2+)and Mn^(2+)concentration.Under elevated CO_(2),the concentration of Fe^(2+)and Mn^(2+)decreased by 14.7%and 13.7%,respectively.We also found that elevated CO_(2) altered rice root aerenchyma structure and promoted rice root ROL.Under elevated CO_(2),rice root ROL increased by 79.5%and 112.2%for Yangdao 6 and Changyou 5,respectively.Warming had no effect on soil Eh and rice root ROL.While warming increased the concentration of Mn^(2+)and SO_(4)^(2-)by 4.9%and 19.3%,respectively.There was a significant interaction between elevated CO_(2) and warming on Fe^(2+)and Mn^(2+).Under elevated CO_(2),warming had no effect on the concentration of Fe^(2+)but decreased Mn^(2+)concentration significantly.Our study demonstrated that elevated atmospheric CO_(2) in the future could increase soil Eh by promoting rice root ROL,which will alter some soil nutrients'availability,such as Fe^(2+)and Mn^(2+). | Jie Li Han Zhang Wenyi Xie Cheng Liu Xiaoyu Liu Xuhui Zhang Lianqing Li Genxing Pan | 2024 | Journal of Environmental Sciences2024,,2: | 0 |
| 13 | Research on Zhuang Medicine Scheflera kwangsiensis Merr.ex Li显示文摘Zhuang medicine Scheflera kwangsiensis Merr.ex Li is a plant of Schefflera in Araliaceae,and its roots,stems and leaves are used as a medicine.In order to fully understand the development and utilization of S.kwangsiensis resources,we analyzed and summarized literatures on crude drug research,planting distribution,harvesting and processing,chemical components,pharmacological effects and quality testing of S.kwangsiensis,aiming to provide a reference basis for establishing the quality standard of Zhuang medicine S.kwangsiensis. | Can LI Ao XIE Yongjing SU Wenyi WEI Gan LUO Haicheng WEN Wei WEI | 2021 | Agricultural Biotechnology2021,10,2: | 0 |
| 14 | Mechanical size effect of eutectic high entropy alloy:Effect of lamellar orientation显示文摘The effect of lamellar orientation on the deformation behavior of eutectic high entropy alloy at the micrometer scale,and the roles of two rarely explored laminate orientations(i.e.,the lamellar orientation at~0°and 45°angles with the loading direction)in regulating size-dependent plasticity were investigated using in-situ micropillar compression tests.The alloy,CoCrFe NiTa_(0.395),consists of alternating layers of Laves and FCC phases.It was found that the yield stress of the 0°pillars scaled inversely with the pillar diameters,in which the underlying deformation mode was observed to transform from pillar kinking or buckling to shear banding as the diameter decreased.In the case of the 450 pillars with diameters ranging from 0.4 to 3μm,there exists a’weakest’diameter of~1μm,at which both constraint effect and dislocation starvation are ineffective.Irrespective of the lamellar orientations,the strain hardening rate decreased with decreasing pillar diameter due to the diminishing dislocation accumulation that originated from the softening nature of large shear bands in the 0°pillars,and the enhanced probability of dislocation annihilation at the increased free surfaces in the 45°pillars.The findings expand and deepen the understanding of the mechanical size effect in small-scale crystalline materials and,in so doing,provide a critical dimension for the development of high-performing materials used for nanoor microelectromechanical systems. | Yujie Chen Xianghai An Sam Zhang Feng Fang Wenyi Huo Paul Munroe Zonghan Xie | 2021 | Journal of Materials Science & Technology2021,,23: | 0 |
| 15 | First experimental comparisons of laser-plasma interactions between spherical and cylindrical hohlraums at SGⅢ laser facility显示文摘We present our recent laser-plasmas instability(LPI)comparison experiment at the SGIII laser facility between the spherical and cylindrical hohlraums.Three kinds of filling are considered:vacuum,gas-filling with or without a capsule inside.A spherical hohlraum of 3.6 mm in diameter,and a cylindrical hohlraum of 2.4 mm?4.3 mm are used.The capsule diameter is 0.96 mm.A flat-top laser pulse with 3 ns duration and up to 92.73 kJ energy is used.The experiment has shown that the LPI level in the spherical hohlraum is close to that of the outer beam in the cylindrical hohlraum,while much lower than that of the inner beam.The experiment is further simulated by using our 2-dimensional radiation hydrodynamic code LARED-Integration,and the laser back-scattering fraction and the stimulated Raman scatter(SRS)spectrum are post-processed by the high efficiency code of laser interaction with plasmas HLIP.According to the simulation,the plasma waves are strongly damped and the SRS is mainly developed at the plasma conditions of electron density from 0.08 n_(c) to 0.1 n_(c) and electron temperature from 1.5 keV to 2.0 keV inside the hohlraums.However,obvious differences between the simulation and experiment are found,such as that the SRS back-scattering is underestimated,and the numerical SRS spectrum peaks at a larger wavelength and at a later time than the data.These dif-ferences indicate that the development of a 3D radiation hydrodynamic code,with more accurate physics models,is mandatory for spherical hohlraum study. | Yaohua Chen Zhichao Li Xufei Xie Chunyang Zheng Chuanlei Zhai Liang Hao Dong Yang Wenyi Huo Guoli Ren Jie Liu Xiaoshi Peng Tao Xu Yulong Li Sanwei Li Zhiwen Yang Liang Guo Lifei Hou Yonggang Liu Huiyue Wei Xiangming Liu Weiyi Cha Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Haijun Zhang Baibin Jiang Wei Zhang Kai Du Xuewei Deng Yongkun Ding Xiaofeng Wei Wanguo Zheng Xiaodong Chen Xiantu He Ke Lan | 2017 | Matter and Radiation at Extremes2017,2,2: | 0 |
| 16 | First demonstration of improving laser propagation inside the spherical hohlraums by using the cylindrical laser entrance hole显示文摘The octahedral spherical hohlraums have natural superiority in maintaining high radiation symmetry during the entire capsule implosion process in indirect drive inertial confinement fusion.While,in contrast to the cylindrical hohlraums,the narrow space between the laser beams and the spherical hohlraum wall is usually commented.In this Letter,we address this crucial issue and report our experimental work conducted on the SGIII-prototype laser facility which unambiguously demonstrates that a simple design of cylindrical laser entrance hole(LEH)can dramatically improve the laser propagation inside the spherical hohlraums.In addition,the laser beam deflection in the hohlraum is observed for the first time in the experiments.Our 2-dimensional simulation results also verify qualitatively the advantages of the spherical hohlraums with cylindrical LEHs.Our results imply the prospect of adopting the cylindrical LEHs in future spherical ignition hohlraum design. | Wenyi Huo Zhichao Li Dong Yang Ke Lan Jie Liu Guoli Ren Sanwei Li Zhiwen Yang Liang Guo Lifei Hou Xuefei Xie Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Guanghui Yuan Haijun Zhang Baibin Jiang Lizhen Huang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Yongkun Ding Xiantu He Weiyan Zhang | 2016 | Matter and Radiation at Extremes2016,1,1: | 0 |