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| 1 | The effect of a urinary incontinence selfmanagement program for older women in South Korea:A pilot study显示文摘Background:Although self-management approaches have shown strong evidence of positive outcomes for urinary incontinence prevention and management,few programs have been developed for Korean rural communities.Objectives:This pilot study aimed to develop,implement,and evaluate a urinary incontinence self-management program for community-dwelling women aged 55 and older with urinary incontinence in rural South Korea.Methods:This study used a one-group pre-post-test design to measure the effects of the intervention using standardized urinary incontinence symptom,knowledge,and attitude measures.Seventeen community-dwelling older women completed weekly 90-min group sessions for 5 weeks.Descriptive statistics and paired t-tests and were used to analyze data.Results:The mean of the overall interference on daily life from urine leakage(pre-test:M=5.76±2.68,post-test:M=2.29±1.93,t=4.609,p<0.001)and the sum of International Consultation on Incontinence Questionnaire scores(pre-test:M=11.59±3.00,post-test:M=5.29±3.02,t=-5.881,p<0.001)indicated significant improvement after the intervention.Improvement was also noted on the mean knowledge(pre-test:M=19.07±3.34,post-test:M=23.15±2.60,t=7.550,p<0.001)and attitude scores(pre-test:M=2.64±0.19,post-test:M=3.08±0.41,t=5.150,p<0.001).Weekly assignments were completed 82.4%of the time.Participants showed a high satisfaction level(M=26.82±1.74,range 22e28)with the group program.Conclusions:Implementation of a urinary incontinence self-management program was accompanied by improved outcomes for Korean older women living in rural communities who have scarce resources for urinary incontinence management and treatment.Urinary incontinence self-management education approaches have potential for widespread implementation in nursing practice. | Jennie C.De Gagne Aeyoung So Bei Wu Mary H.Palmer Eleanor S.McConnell | 2015 | International Journal of Nursing Sciences2015，2，1： | 3 |
| 2 | Surgical intervention combined with weight-bearing walking training improves neurological recoveries in 320 patients with clinically complete spinal cord injury:a prospective self-controlled study显示文摘Although a large number of trials in the SCI field have been conducted,few proven gains have been realized for patients.In the present study,we determined the efficacy of a novel combination treatment involving surgical intervention and long-term weight-bearing walking training in spinal cord injury(SCI)subjects clinically diagnosed as complete or American Spinal Injury Association Impairment Scale(AIS)Class A(AIS-A).A total of 320 clinically complete SCI subjects(271 male and 49 female),aged 16–60 years,received early(≤7 days,n=201)or delayed(8–30 days,n=119)surgical interventions to reduce intraspinal or intramedullary pressure.Fifteen days post-surgery,all subjects received a weight-bearing walking training with the“Kunming Locomotion Training Program(KLTP)”for a duration of 6 months.The neurological deficit and recovery were assessed using the AIS scale and a 10-point Kunming Locomotor Scale(KLS).We found that surgical intervention significantly improved AIS scores measured at 15 days post-surgery as compared to the pre-surgery baseline scores.Significant improvement of AIS scores was detected at 3 and 6 months and the KLS further showed significant improvements between all pair-wise comparisons of time points of 15 days,3 or 6 months indicating continued improvement in walking scores during the 6-month period.In conclusion,combining surgical intervention within 1 month post-injury and weight-bearing locomotor training promoted continued and statistically significant neurological recoveries in subjects with clinically complete SCI,which generally shows little clinical recovery within the first year after injury and most are permanently disabled.This study was approved by the Science and Research Committee of Kunming General Hospital of PLA and Kunming Tongren Hospital,China and registered at ClinicalTrials.gov(Identifier:NCT04034108)on July 26,2019. | Yansheng Liu Jia-Xin Xie Fang Niu Zhexi Xu Pengju Tan Caihong Shen Hongkun Gao Song Liu Zhengwen Ma Kwok-Fai So Wutian Wu Chen Chen Sujuan Gao Xiao-Ming Xu Hui Zhu | 2021 | Neural Regeneration Research2021，16，5： | 3 |
| 3 | All roads lead to Rome-a review of the potential mechanisms by which exerkines exhibit neuroprotective effects in Alzheimer’s disease显示文摘Age-related neurodegenerative disorders such as Alzheimer’s disease(AD)have become a critical public health issue due to the significantly extended human lifespan,leading to considerable economic and social burdens.Traditional therapies for AD such as medicine and surgery remain ineffective,impractical,and expensive.Many studies have shown that a variety of bioactive substances released by physical exercise(called“exerkines”)help to maintain and improve the normal functions of the brain in terms of cognition,emotion,and psychomotor coordination.Increasing evidence suggests that exerkines may exert beneficial effects in AD as well.This review summarizes the neuroprotective effects of exerkines in AD,focusing on the underlying molecular mechanism and the dynamic expression of exerkines after physical exercise.The findings described in this review will help direct research into novel targets for the treatment of AD and develop customized exercise therapy for individuals of different ages,genders,and health conditions. | Yi-Yao Liang Li-Dan Zhang Xi Luo Li-Li Wu Zhao-Wei Chen Guang-Hao Wei Kai-Qing Zhang Ze-An Du Ren-Zhi Li Kwok-Fai So Ang Li | 2022 | Neural Regeneration Research2022，17，6： | 2 |
| 4 | A fast algorithm for 2-D direction-of-arrival estimation显示文摘 | Wu Y Liao G So H C | 2003 | Signal Processing2003，83，8： | 1 |
| 5 | Chondroitinase ABC promotes axonal regeneration of Clark's neurons after spinal cord injury 显示文摘 | Yick LW Wu W So KF | 2000 | Neuroreport2000，11，5： | 1 |
| 6 | Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells显示文摘 | Huanxing Su Lihui Wang Wenhao Huang Dajiang Qin Jinglei Cai Xiaoli Yao Chengqian Feng Zhiyuan Li Yitao Wang Kwok-Fai So Guangjin Pan Wutian Wu Duanqing Pei | 2013 | Stem Cell Research2013，，： | 1 |
| 7 | Emotional quality - of - life and outcomes in adolescents with asthma 显示文摘 | Okelo SO Wu AW Krishnan JA | 2004 | J Pediatr2004，145，4： | 1 |
| 8 | On wavelet denoising and its application to time delay estimation 显示文摘 | Ching P C So H C Wu S Q | 1999 | IEEE Trans on SP1999，47，10： | 1 |
| 9 | Multi-lipofection efficiently transfected genes into astrocytes in primary culture显示文摘 | Wu BY Liu RY So KL | 2000 | J Neurosci Methods2000，102，2： | 1 |
| 10 | Stress-inducible synthesis of proline in transgenic rice confers faster growth under stress conditions than that with constitutive synthesis显示文摘 | So J Wu R | 2004 | Plant Science2004，166，： | 1 |
| 11 | Effects of neurotrophic factors on motoneuron surviral following axonal injury in newborn rats显示文摘 | YuanQ Wu W So KF | 2000 | Neuroreport2000，11，10： | 1 |
| 12 | Thrombin and phenotypic modulation of the endothelium 显示文摘 | Minami T Sugiyama A Wu SO | 2004 | Arterioscler Thromb Vasc Biol2004，24，1： | 1 |
| 13 | Molecular epidemiology of Salmonella enterica serovar enteiritdis isolated in Taiwan显示文摘 | So LH Chin CH Wu TL | 2002 | Microbiol Immunol2002，46，12： | 1 |
| 14 | Subspace-based algorithm for parameter estimation of polynomial phase signals 显示文摘 | Y Wu HC So H Liu | 2008 | IEEE Tram Signal Process2008，56，10： | 1 |
| 15 | The BK potassium channel in the vas- cular smooth muscle and kidney : α-and β-subunits 显示文摘 | Wu RS Marx SO | 2010 | Kidney Int2010，78，10： | 1 |
| 16 | Novel interaction between the co-chaperone CDC37 and rho GTPase exchange factor Vav3 pro- motes androgen receptor activity and prostate cancer growth显示文摘 | Wu F Peacock SO Rao S | 2013 | J Biol Chem2013，288，8： | 1 |
| 17 | Effect of hyperglycemia and continuous intravenous insulin infusions on outcomes of cardiac surgical procedures: the Portland Diabetic Project显示文摘 | Furnary AP Wu Y Bookin SO | 2004 | Endocr Pract2004，10，2： | 1 |
| 18 | Subspace-Based Algorithm for Parameter Estimation of Polynomial Phase Signals显示文摘 | Yuntao Wu hing Cheung So Hongqing Liu | 2008 | IEEE Transactions on Signal Processing2008，56，10： | 1 |
| 19 | On wavelet de-noising and its application to time delay estimation显示文摘 | Ching P C So H C Wu S Q | 1999 | IEEE Trans on Signal Processing1999，47，10： | 1 |
| 20 | Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2显示文摘 | Wu C So J Davis-Dusenbery BN | 2011 | Mol Cell Biol2011，31，23： | 1 |
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