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| 1 | Apolipoprotein E, angiotensin-converting enzyme and kallikrein gene polymorphisms and the risk of Alzheimer's disease and vascular dementia显示文摘 | Wang HK Fung HC Hsu WC Wu YR Lin JC Ro LS Chang KH Hwu FJ Hsu Y Huang SY Lee-Chen GJ Chen CM | 2006 | 中国生物学文摘2006，20，8： | 8 |
| 2 | Lean techniques for the improvement of patients' flow in emergency department显示文摘BACKGROUND: Emergency departments(EDs) face problems with overcrowding, access block, cost containment, and increasing demand from patients. In order to resolve these problems, there is rising interest to an approach called 'lean' management. This study aims to(1) evaluate the current patient flow in ED,(2) to identify and eliminate the non-valued added process, and(3) to modify the existing process.METHODS: It was a quantitative, pre- and post-lean design study with a series of lean management work implemented to improve the admission and blood result waiting time. These included structured re-design process, priority admission triage(PAT) program, enhanced communication with medical department, and use of new high sensitivity troponin-T(hsTnT) blood test. Triage waiting time, consultation waiting time, blood result time, admission waiting time, total processing time and ED length of stay were compared.RESULTS: Among all the processes carried out in ED, the most time consuming processes were to wait for an admission bed(38.24 minutes; SD 66.35) and blood testing result(mean 52.73 minutes, SD 24.03). The triage waiting time and end waiting time for consultation were significantly decreased. The admission waiting time of emergency medical ward(EMW) was significantly decreased from 54.76 minutes to 24.45 minutes after implementation of PAT program(P<0.05).CONCLUSION: The application of lean management can improve the patient flow in ED. Acquiescence to the principle of lean is crucial to enhance high quality emergency care and patient satisfaction. | HY Chan SM Lo LLY Lee WYL Lo WC Yu YF Wu ST Ho RSD Yeung JTS Chan | 2014 | World Journal of Emergency Medicine2014，5，1： | 6 |
| 3 | Derivation of hypermethylated pluripotent embryonic stem cells with high potency显示文摘天真的 hypomethylated 胚胎的 pluripotent 干细胞(转换字符) 离胚囊的 preimplantation epiblast 发展地最靠近,与潜力到贡献所有胚胎的纸巾和 germline,除了在妄想的胚胎的胚胎外的纸巾。由对比,类似于 postimplantation epiblast 的 epiblast 干细胞(EpiSCs ) 是相对更多的 methylated 和表演为 chimerism 的一个有限潜力。第一次,这里,我们在 pluripotent 房间以外发展地揭示先进 pluripotent 干细胞(ASC ) ,它是在内部房间团中,但是与更高的力量比 EpiSCs。因此,单个 ASC 在怪物很高效地作出贡献到胎儿, germline,蛋黄囊和胎盘的迷宫。因为他们是,发展地,更多进展了, ASC 不贡献 trophoblast。ASC 在与 Activin A 和基本成纤维细胞生长因素补充的化学上定义的媒介在二个步骤从胚囊被导出,在包含 ActA, BMP4, CHIR99021 和白血病的 ABCL 媒介由 culturing 列在后面禁止的因素。尤其是, ASC 与天真的 pluripotency 基因,以及 mesodermal 的表示展出不同 transcriptome 体的基因;Eomes,时代, Tdgf1, Evx1, hand1, Wnt5a 和不同重复元素。到 ASC 的确定的转换字符的变换也是可完成的。重要地, ASC 作为与 hypomethylated 相比展出稳定的 hypermethylated epigenome 和主要未经触动的印记胚囊和天真的转换字符的内部房间质量。ASC 的性质建议他们以在 pluripotency 的天真、告知的状态之间的一个中间的细胞的状态代表房间。 | Siqin Bao Walfred WC Tang Baojiang Wu Shinseog Kim Jingyun Li Lin Li Toshihiro Kobayashi Caroline Lee Yanglin Chen Mengyi Wei Shudong Li Sabine Dietmann Fuchou Tang Xihe Li | 2018 | Cell Research2018，28，1： | 4 |
| 4 | Use of dynamic capillaroscopy for studying cutaneous microcirculation in patients with diabetes mellitus显示文摘 | Chang CH Tsai RK Wu WC | 1997 | Microvas Res1997，53，2： | 1 |
| 5 | The long-term anatomical and visual effect of intravitreal triamcinolone injection during vitrectomy for the treatment of idiopathic macular epiretinal membrane 显示文摘 | Lai CC Wang NK Wu WC | 2011 | Cutan Ocul Toxicol2011，30，： | 1 |
| 6 | Second-line therapy for elderly patients- with non-small cell lung cancer who failed previous chemotherapy is as ef- fective as for younger patients 显示文摘 | Wu CH Fan WC Chen YM | 2010 | J Thorac Oncol2010，5，3： | 1 |
| 7 | Advances in molecularbiomarkers for gastric cancer: miRNAs as emerging novelcancer markers显示文摘 | Wu HH Lin WC Tsai KW | 2014 | Expert Rev Mol Med2014，16，： | 1 |
| 8 | The molecular mechanism of actinomycin D in preventing neointimal formation in rat carotid arter- ies after balloon injury显示文摘 | Wu CH Pan JS Chang WC | 2005 | J Biomed Sci2005，12，3： | 1 |
| 9 | Prevalence of Plasmid-Mediated Quinolone Resistance Determinants, QnrA, QnrB, and QnrS, among Clinical Isolates of Enterobacter cloacae in a Taiwanese Hospital 显示文摘 | Wu J J Ko WC Tsai SH | 2007 | Antimicrob Agents Chemother2007，51，4： | 1 |
| 10 | Plasmid-mediated 16S rRNA methylases conferring high-level aminoglycoside resistance in escherichia coli and klebsiella pneumoniae isolates from two Taiwanese hospitals显示文摘 | Yan JJ Wu JJ Ko WC | 2004 | J Antimicrob Chemother2004，54，： | 1 |
| 11 | Detecting Epstein-Barr virus DNA from peripheral blood mononuclear cells in adult patients with systermic lupus erythematosus in Taiwan显示文摘 | Yu SF Wu HC Tsai WC | 2005 | Med Microbiool Immunol(Berl)2005，194，3： | 1 |
| 12 | Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital显示文摘 | Wu JJ Ko WC Tsai SH | 2007 | Antimierob Agents Chemother2007，51，4： | 1 |
| 13 | The impact of CD4+ CD25+ T ceils in the tumor microenvironment of hepatocellular carcinoma显示文摘 | Lee WC Wu TJ Chou HS | 2012 | Surgery2012，151，2： | 1 |
| 14 | Dexamethasone and pentastarch produce additive attenuation of ischaemia/ reperfusion lung injury显示文摘 | Chiang CH Wu CP Perng WC | 2000 | Clin Sci2000，99，5： | 1 |
| 15 | Optimization of microcarrier cell culture process for the inactivated enterovirus type 71 vaccine de- velopment 显示文摘 | Wu SC Liu CC Lian WC | 2004 | Vaccine2004，22，2930： | 1 |
| 16 | Contemporary man- agement of penile cancer including surgery and adjuvant radiotherapy: an experience inTaiwan 显示文摘 | Chen MF Chen WC Wu CT | 2004 | World J Urol2004，22，1： | 1 |
| 17 | Mitochondria mediated caspase independent apoptosis induced by cadmium in normal human hmg, cells 显示文摘 | Shih CM Wu J-S Ko WC | 2003 | Cell Biochem2003，89，9： | 1 |
| 18 | A randomized controlled trial of modified con- straint-induced movement therapy for elderly stroke survivors: Changes in motor impairment, daily functioning, and quality of life 显示文摘 | Wu CY Chen CL Tsai WC | 2007 | Archives of Physical Medicine and Rehabilitation2007，88，3： | 1 |
| 19 | Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF显示文摘 | Liang WC Wu X Peale FV | 2006 | Biol Chem2006，281，： | 1 |
| 20 | Usefulness of Doppler spectral analysis and power Doppler sonography in the differentiaition cervical lymphadenophathies显示文摘 | Wu CH Chang TL Has Wc | 1998 | Am J Roentgenol1998，171，2： | 1 |
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