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| 1 | The Qitai radio telescope显示文摘This study presents a general outline of the Qitai radio telescope(QTT)project.Qitai,the site of the telescope,is a county of Xinjiang Uygur Autonomous Region of China,located in the east Tianshan Mountains at an elevation of about 1800 m.The QTT is a fully steerable,Gregorian-type telescope with a standard parabolic main reflector of 110 m diameter.The QTT has adopted an umbrella support,homology-symmetric lightweight design.The main reflector is active so that the deformation caused by gravity can be corrected.The structural design aims to ultimately allow high-sensitivity observations from 150 MHz up to115 GHz.To satisfy the requirements for early scientific goals,the QTTwill be equipped with ultra-wideband receivers and large field-of-view multi-beam receivers.A multi-function signal-processing system based on RFSo C and GPU processor chips will be developed.These will enable the QTT to operate in pulsar,spectral line,continuum and Very Long Baseline Interferometer(VLBI)observing modes.Electromagnetic compatibility(EMC)and radio frequency interference(RFI)control techniques are adopted throughout the system design.The QTT will form a world-class observational platform for the detection of lowfrequency(nano Hertz)gravitational waves through pulsar timing array(PTA)techniques,pulsar surveys,the discovery of binary black-hole systems,and exploring dark matter and the origin of life in the universe.The QTT will also play an important role in improving the Chinese and international VLBI networks,allowing high-sensitivity and high-resolution observations of the nuclei of distant galaxies and gravitational lensing systems.Deep astrometric observations will also contribute to improving the accuracy of the celestial reference frame.Potentially,the QTT will be able to support future space activities such as planetary exploration in the solar system and to contribute to the search for extraterrestrial intelligence. | Na Wang Qian Xu Jun Ma Zhiyong Liu Qi Liu Hailong Zhang Xin Pei Maozheng Chen Richard N.Manchester Kejia Lee Xingwu Zheng Hans J.Kärcher Wulin Zhao Hongwei Li Dongwei Li Martin Süss Matthias Reichert Zhongyi Zhu Congsi Wang Mingshuai Li Rui Li Ning Li Guljaina Kazezkhan Wenming Yan Gang Wu Lang Cui Ming Zhang Haitao Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 14 |
| 2 | Tonifying Qi and activating blood circulation in terms of Traditional Chinese Medicine: their effects in patients with myocardial infarction显示文摘OBJECTIVE: To investigate the effects of tonifying Qi and activating blood circulation(SQABC), a method in Traditional Chinese Medicine(TCM), on end-point events in patients with myocardial infarction(MI) in this retrospective cohort study.METHODS: Clinical data were obtained from the medical records of patients with acute MI(AMI),both during hospitalization and follow-up, and included general demographic information(age, gender, and contact information), TCM regimens used,and end-point events.RESULTS: A total of 1596 patients with AMI were enrolled to this study, but data of only 1210 casesare accessible till follow-up. We classified the patients based on the exposure levels of SQABC.When comparing the results between all exposure and non-exposure groups, significant differences were identified, both during hospitalization and follow-ups. During hospitalization, cardiac death(4.40% vs 21.55%, P < 0.05) and cardiac shock(3.04% vs 11.62%, P < 0.05) were significantly lower in the exposure group than the non-exposure group. Similarly, during the follow-up, cardiac death(12.04% vs 20.49%, P < 0.05), acute heart failure(7.27% vs 11.81%, P < 0.05), composite endpoint of reinfarction and stroke(9.11% vs 15.28%,P < 0.05), and rehospitalization due to angina(25.49% vs 34.38%, P < 0.05) were significantly lower in the exposure group than the non-exposure group.CONCLUSION: Our findings suggest that SQABC can significantly benefits the subjects in the management of high-risk AMI in them. | Gao Wulin Dai Guohua Zhang Tong Bi Dongxue Liu Chunhua Shi Xiaojing Zhao Fang Zhao Chen | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 7 |
| 3 | Efficacy of Traditional Chinese Medicine in patients with acute myocardial infarction suffering from diabetes mellitus显示文摘OBJECTIVE: To investigate the 'real world' effectiveness of Traditional Chinese Medicine(TCM) in patients with acute myocardial infarction suffering from diabetes mellitus(AMI+DM patients).METHODS: This was a retrospective cohort study.During hospitalization, the 'exposure group' was defined as patients who had a TCM injection for ≥ 7 d.During follow-up, the definition of the exposure group was application of a Chinese patent medicine or decoction of Chinese medicine for ≥ 28 d.General information(age, sex, contact details), TCM use and endpoint events of AMI+DM patients during hospitalization and follow-up were collected.The correlation between TCM and the end-point events of AMI + DM patients was analyzed using a multiple logistic regression method.RESULTS: A total of 479 AMI + DM patients were enrolled and 345 cases were followed up. During hospitalization, TCM, age, hypertension and use of an angiotensin-converting enzyme inhibitor(ACEI)or angiotensin receptor blocker(ARB) were associated with cardiac death. During follow-up, TCM was associated with cardiac death. TCM was a relevant factor for a composite endpoint of re-infarction and stroke. TCM, anti-thrombotic therapy and lipid-lowering therapy were related to acute heart failure. TCM, anti-thrombotic therapy, anti-MI therapy and ACEI/ARB use exhibited a strong correlation with re-hospitalization due to cardiovascular disease.CONCLUSION: TCM reduced the prevalence of cardiac death during hospitalization, and cardiac death, a composite endpoint of re-infarction and stroke, acute heart failure and re-hospitalization due to cardiovascular disease during follow-up. | Dai Guohua Gao Wulin Bi Dongxue Liu Chunhua Liu Yuhan Wang Ning Zhao Chen | 2018 | Journal of Traditional Chinese Medicine2018，38，3： | 4 |
| 4 | Research Progress in Laser Active Debris Removal of CAST显示文摘Based on the introduction to theresearch status and trend of international space-based laser debris re-moval technology, the existing problems of space-based laser debris removal technology are systematically analyzed.In view of the existing problems, the work and research progress of the Beijing Institute of Spacecraft EnvironmentEngineering in this field are introduced from several aspects, such as dynamic behavior of laser-driven debris, orbittransfer model, ground simulation system, space-based removal system scheme and target selection strategy. The mainresearch methods include laser-driven micro-impulse measurement experiment, surface triangulation three-dimension-al reconstruction calculation method based on laser-material interaction theory, simulation calculation based on orbitaldynamics, etc. It also looks forward to the future research direction in the field of this technology. | CHEN Chuan YANG Wulin GONG Zizheng LI Ming | 2018 | Aerospace China2018，19，4： | 3 |
| 5 | Corrosion resistance of sintered NdFeB magnets with various surface coating显示文摘 | Chen E Peng K Yang Wulin | 2014 | Applied'' Mechanics and Materials2014，492，： | 1 |
| 6 | Image zooming for indexed color images based on bilinear interpolation显示文摘 | Hu Yuchen Su Binghwang Chen Wulin | 2012 | International Journal of Multimedia and Ubiquitous Engineering2012，7，2： | 1 |
| 7 | Thermal property and microstructure of aluminum nanopowders pro- duced by two evaporation routes 显示文摘 | Chen Liang Song Wulin Guo Liangui | 2009 | Trans Nonferrous Metals Soc China2009，19，1： | 1 |
| 8 | Morphology and size control of inorganic particles in polyimide hybrids by using SiO2-TiO2 mixed oxide显示文摘 | Qiu Wulin Luo Yunjun Chen Futai | 2003 | Polymer2003，44，19： | 1 |
| 9 | Morphology and Size Control of Inorganic Particles in Polyimide Hybrids by Using SiO2-TiO2 Mixed Oxide显示文摘 | Wulin Qiu Yunjun Luo Futai Chen | 2003 | Polymer2003，，44： | 1 |
| 10 | Functional expression of cystic fibrosis transmembrane conductance regulator in rat oviduct epithelium显示文摘这研究的目的是在老鼠输卵管上皮与 electrophysiological 和分子的技术调查膀胱的纤维变性 transmembrane 传导力管理者(CFTR ) 的功能的表示。在整个房间的补丁夹钳,上皮的房间在没有差距的模式在里面的电流与上升对 100 M 8-bromo-adenosine 3,5-cyclic monophosphate ( 8-Br-cAMP )作出回应的输卵管,它被 5 M CFTR ( inh )-172,连续地禁止一个 CFTR 特定的禁止者,和 1 公里 diphenylamine-2-carboxylate ( DPC ), Cl -隧道 blocker 。激活营地的水流展出了一线性当前电压(I-V ) 关系和时间无关、电压无关的特征。在对称的 Cl - 答案的激活营地的水流的颠倒潜力接近了 Cl - 平衡, 0.5 湩愠獮敷 ? 潴吗? | Minhui Chen Jianyang Du Weijian Jiang Wulin Zuo Fang Wang Manhui Li Zhongluan Wu Hsiaochang Chan Wenliang Zhou | 2008 | Acta Biochimica et Biophysica Sinica2008，40，10： | 0 |
| 11 | Coronal multi-walled silicon nanotubes显示文摘By means of first-principles density functional theory(DFT) calculations and molecular dynamics(MD) simulations,a series of coronal multi-walled silicon nanotubes(MWSiNTs) without or with hydrogen terminations are systematically identified.Notably,coronal MWSiNTs,where the interaction between the walls is preferable through covalent bonds rather than weak interaction,show better stability than CNT-like SiNTs. Moreover,they exhibit good elasticity with small Young’s modulus.The investigation of the electronic structure demonstrates that they present metallic characteristics,which is in striking contrast to bulk silicon.Thus,the MWSiNTs may find important applications in electronic devices. | Yuanshuai Zhu Zhibei Qu Guilin Zhuang Wulin Chen Jianguo Wang | 2013 | Journal of Energy Chemistry2013，22，3： | 0 |
| 12 | 低轨大规模星座对空间碎片环境的影响及其应对措施显示文摘Large constellations have developed rapidly in recent years because of their unique advantages, but they will inevitably have a major negative impact on the space debris environment, leading to its deterioration. The key to mitigate the impact is the success rate and duration of the post-mission disposal(PMD) process. Aiming at solving this problem, this paper further studies the impact of large constellations on other space assets under different PMD strategies through simulation, and proposes corresponding strategies and suggestions for mitigation.According to One Web’s large constellation launch plan, the dangerous intersection of the large constellation with existing space assets at different stages of the constellations life cycle is calculated by simulation. Based on this, the influence of the large constellation operation on existing space assets at different times and strategies of PMD is analyzed. The conclusion shows that in the PMD stage, large constellations have the greatest impact on existing space assets;the PMD duration and number of satellites performing PMD at the same time are key factors to the degree of negative impact. The faster the PMD is, the less threat it poses to other spacecraft. More results and conclusions are still being analyzed. | CHEN Chuan YANG Wulin GONG Zizheng ZHANG Pinliang LI Ming | 2020 | Aerospace China2020，21，2： | 0 |
| 13 | Characterization of amyloid-β precursor protein intracellular domain-associated transcriptional complexes in SH-SY5Y neurocytes显示文摘Objective Alzheimer's disease (AD) is one of the major disorders worldwide. Recent research suggests that the amyloid-β precursor protein intracellular domain (AICD) is a potential contributor to AD development and progression. The small AICD is rapidly degraded after processing from the full-length protein. The present study aimed to apply a highly efficient biotinylation approach in vitro to study AICD-associated complexes in neurocytes. Methods By coexpressing Escherichia coli biotin ligase with biotinyl-tagged AICD in the SH-SY5Y neuronal cell line, the effects of AICD overexpression on cell proliferation and apoptosis were analyzed. Besides, AICD-associated nuclear transcriptional complexes were purified and then examined by mass spectrometry. Results Our data showed that AICD overexpression not only affected cell proliferation but also led to apoptosis in differentiated SH-SY5Y cells. Moreover, biotinylation allowed single-step purification of biotinylated AICD-associated complexes from total nuclear extract via high-affinity biotin-streptavidin binding. Following this by mass spectrometry, we identified physically associated proteins, some reported previously and other novel binding partners, CUX1 and SPT5. Conclusion Based on these results, a map of the AICD-associated nuclear interactome was depicted. Specifically, AICD can activate CUX1 transcriptional activity, which may be associated with AICD-dependent neuronal cell death. This work helps to understand the AICD-associated biological events in AD progression and provides novel insights into the development of AD. | Wulin Yang Amy Yong Chen Lau Shuizhong Luo Qian Zhu Li Lu | 2012 | Neuroscience Bulletin2012，28，3： | 0 |
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