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| 1 | An iterative stabilized fractional step algorithm for finite element analysis in saturated soil dynamics显示文摘 | Li Xikui Han Xianhong Pastor M | 2003 | Computer Methods in Applied Mechanics and Engineering2003，192，： | 1 |
| 2 | A mixed finite element scheme for viscoelastic flows with XPP model显示文摘为粘弹性的流动的混合有限元素明确的表达在这篇论文被导出,在哪个 FIC (有限增长演算)压力稳定过程和 DEVSS (分离橡皮粘滞切开的应力)用 Crank-Nicolson-based 裂口的方法在部分步算法的反复的版本的一个一般框架以内被介绍。苏(优化迎风) 方法特别地被选择在粘弹性的流动的组成的方程处理对流术语。由于建议计划,有为 stress-velocity-pressure 变量的相等的低顺序的插值近似的有限元素能成功地与高 Weissenberg 数字甚至为粘弹性的流动被使用。XPP (扩大大型机关炮) 为描述粘弹性的行为的组成的模型特别地集成于建议计划。 4:1 的数字结果突然的收缩流动问题证明突出的稳定性,精确性和集中在大量 theWeissenberg 数字以内在流动领域上在压力和压力分布建议计划评价,特别地在复制结果的能力,它能被用来解释“死胀大”在聚合物观察的现象注射塑造过程。 | Xianhong Han Xikui Li | 2008 | Acta Mechanica Sinica2008，24，6： | 1 |
| 3 | An iterative stabilized fractional step algorithm for finite element analysis in saturated soil dynamics显示文摘 | Li Xikui Han Xianhong Pastor M | 2003 | Comput Methods Appl Mech Engrg2003，192，： | 1 |
| 4 | An iterative stabilized fractional step algorithm for finite element analysis in saturated soil dynamics显示文摘 | LI XIKUI HAN XIANHONG PASTOR M | 2003 | Computer Methods in Applied Mechanics and Engineering2003，192，6： | 1 |
| 5 | Adaptive coupled arbitrary Lagrangian-Eulerian finite element and meshfree method for injection molding process 显示文摘 | Li Xikui Duan Qinglin Han Xianhong Sheng D C | 2008 | International Journal for Numerical Methods in Engineering2008，73，8： | 1 |
| 6 | Nicotine and menthol independently exert neuroprotective effects against cisplatin-or amyloid-toxicity by upregulating Bcl-xl via JNK activation in SH-SY5Y cells显示文摘Nicotine and menthol,agonists of nicotinic acetylcholine receptor(nAChR)and transient receptor potential melastatin type 8(TRPM8),serve important roles in the prevention of cell death-involved neurodegenerative diseases.However,the potential synergistic effects of nicotine and menthol on anti-apoptotic ability are still uncertain.In the present study,the potential synergistic effects of nicotine and menthol on cisplatin or amyloidβ1-42 induced cell model of the neurodegenerative diseases were explored by assessing cell viability,TNF-αexpression,caspase-3 activation,and the collapse of mitochondrial membrane potential in human SH-SY5Y neuroblastoma cells.Statistical significance was tested using Student’s t-test or one-way ANOVA with post hoc Newman-Keuls test.The results showed that:Firstly,SH-SY5Y cell viability was obviously increased by the treatments with nicotine and menthol.Secondly,nicotine and menthol independently alleviated cisplatin or amyloidβ1-42 induced TNF-αup-regulation.Thirdly,nicotine and menthol abrogated the effect of cisplatin and amyloidβ25-35 on caspase-3 activation.Interestingly,the effect of cisplatin and amyloidβ1-42 on the collapse of mitochondrial membrane potential was efficiently attenuated by nicotine and menthol treatments.Most importantly,the inhibition of c-jun kinase(JNK)activation abolished the effect of cisplatin,and amyloidβ1-42 stimulated Bcl-xl expression.All these findings indicate that nicotine and menthol independently exert neuroprotective effects by upregulating Bcl-xl via JNK activation.Nicotine and menthol augmented Bcl-xl expression and JNK phosphorylation,and thus they are potential therapeutic targets for altering the progress of neurodegenerative diseases. | YIBIN RUAN ZHONGMING XIE QIONG LIU LIXIAO ZHANG XIKUI HAN XIAOYAN LIAO JIAN LIU FENGGUANG GAO | 2021 | BIOCELL2021，45，4： | 0 |
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