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| 1 | Role of β-microseminoprotein from prostate cancer initiationto recurrence: A mini-review显示文摘Medline/Pubmed articles relevant to this topic were considered using the search terms ?-microseminoprotein, MSMB, prostate secretory protein of 94 amino acids and PSP94. Full articles were retrieved when the abstract was considered relevant. In addition, other data related to this topic including our own are discussed. Summary of fi ndings-?-microseminoprotein(MSMB) is increasingly being considered as a marker for prostatecancer, as reduced levels have been associated with the disease. Here we review various aspects of this protein including its biological and physiological variants, binding proteins and immune modulation; its importance as a marker for biochemical recurrence of prostate cancer; prostate cancer related splice variants and its therapeutic utility. Two of the most important properties of MSMB are related to anticancer functions and immune modulation. Predominant expression of two(short and full-length) splice variants of MSMB has been observed from normal prostate and several other tissues. In benign prostate hyperplasia the short isoform is dominant, constituting 98% of this isoform, whereas in prostate cancer 96% constitute the fulllength isoform. The MSMB promoter single nucleotide polymorphism rs10993994 with the C allele functions as an activated cyclic adenosine monophosphate response element binding protein binding site. This C variant of rs10993994 could be responsible for the production of splice variants under variable conditions. MSMB has binding motifs to a few known proteins including immunoglobulin G and several Cysteine-rich secretory proteins family proteins. MSMB bound to these proteins is considered as immune modulating. Use of MSMB as a urinary marker for detecting aggressive prostate cancers that could resist radiation and surgical treatments, seems possible, but needs further investigation. The ratio of MSMB splice variants could also be a possible approach in understanding prostate cancers, with higher ratios indicating severe disease. | Nishi Karunasinghe Karen Bishop Pamela Murray Yuanye Xu Megan Goudie Lance Ng Shuotun Zhu Dug Yeo Han Lynnette R Ferguson Jonathan Masters Benji Benjamin Michael Holmes | 2014 | World Journal of Clinical Urology2014，3，1： | 2 |
| 2 | Synthesis of menoporous alumina with highly thermal stability using glucose template inaqueous system显示文摘 | Benjiing Xu Tianeun Xiao | 2006 | Microporous and Mesoporous Materials2006，91，： | 1 |
| 3 | Reaction cross section studies of ^(12)C using the modified Glauber model in conjunction with nonlinear relativistic mean-field theory显示文摘We studied the structure of 12 C through the modified Glauber model using the density distributions calculated by the relativistic mean field theory. The experimental reaction cross sections of 12 C + 12 C were analyzed within the MOL by a χ 2 -fitting procedure. The effects of the nuclear deformation on the reaction cross sections are studied. The reliable structure of 12 C is deduced. The studies show that the conjunction of these two models will be a more effective tool to study the properties of nuclei. | FUKUDA Mitsunori FAN Guangwei AN Zhendong CAI Xiaolu FAN Gongtao HUANG Bosong LI Yongjiang XU Benji YAN Zhe XU Wang | 2012 | Nuclear Science and Techniques2012，23，5： | 0 |
| 4 | Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice显示文摘The level of lipid peroxidation and cellular necrosis in rat living brain slices during brain ischemia-hypoxia injury have been observed using a laser confocal scanning microscope (LCSM) with double labeling of fluorescent probes D-399 (2, 7-dichlorofluorescin diacetate) and propidium iodide (Pl). The hypoxia and/or reoxygenation injury in rat brain slices is markedly decreased by pretreatment with L-NG-nitro-arginine (L-NNA) and N-acetylcysteine (NAC), showing that the nitric oxide (NO) and other free radicals play an important role in brain ischemia-hypoxia injury. | WANG Xiaoying XING Hong HE Qihua XU Jialing WU Benjie | 2000 | Chinese Science Bulletin2000，45，1： | 0 |
| 5 | Computational Investigation of the Interaction Between Hydrogen Atoms and an Intense Circularly Polarized Laser Field显示文摘The study of interactions between a high-power laser and atoms has been one of the fundamental and interesting topics in strong field physics for decades.Based on a nonperturbativemodel,ten years ago,we developed a set of programs to facilitate the study of interactions between a circularly polarized laser and atomic hydrogen.These programs included only contribution from the bound states of the hydrogen atom.However,as the laser intensity increases,contribution from continuum states to the excitation and ionization processes becomes larger and can no longer be neglected.Furthermore,because the original code is not able to add this contribution directly due to its many disadvantages,a major upgrade of the code is required before including the contribution from continuum states in future.In this paper,first we deduce some important formulas for contribution of continuum states and present modifications and tests for the upgraded code in detail.Second we show some comparisons among new results,old results from the original codes and the available experimental data.Overall the new result agrees with experimental data well.Last we present our calculation of above-threshold ionization(ATI)rate and compare it with a pertubative calculation.The comparison shows that our nonperturbative calculation can also produce ATI peak suppression. | Lifeng Yang Wang Xu Qiren Zhang Wen Luo Qiangyan Pan Xiaolu Cai Gongtao Fan Yongjiang Li Benji Xu Zhe Yan Guangwei Fan Zhendong An | 2012 | Communications in Computational Physics2012，11，3： | 0 |
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