|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The Distribution of Different Clades of Seneca Valley Viruses in Guangdong Province,China显示文摘Seneca Valley virus (SVV), a newly determined etiological agent of vesicular disease in swine, causes porcine idiopathic disease and occasional acute death in piglets. Recently, an increased number of SVV infection cases have been reported in the United States (US) and China, resulting in significant economic losses to the swine industry. The first identification of SVV in China was reported in Guangdong Province, a major swine producing province. The cases of SVV were continuously reported in Guangdong in 2015 and 2016. However, the spread of SVV in Guangdong in 2017 remains unknown.In this study, we determined two new SVV strains, CH-GD-2017-1 and CH-GD-2017-2, from Guangdong. The genetic analysis suggested that the two Guangdong strains showed different characteristics to previous Guangdong strains. They showed lower nucleotide similarity with strains isolated in 2015 and 2016, and were more similar to the US strains.Phylogenetic analyses indicated that the new strains were clustered in a different clade with previous Guangdong strains.We found 28 mutated amino acids in the new strains, compared with the first Guangdong strain, SVV CH-01-2015. In the geographic analysis, we found that the US and China reported more SVV cases than other countries, and most of the SVV cases were reported in east and central China—of which, Guangdong Province is one of the major epidemic regions. In conclusion, our findings indicate that SVV continued to spread in Guangdong Province in 2017, and two different clades of SVVs have emerged in this region. | Pan Chen Fan Yang Weijun Cao Huanan Liu Keshan Zhang Xiangtao Liu Zhiwen Xu Zixiang Zhu Haixue Zheng | 2018 | Virologica Sinica2018，33，5： | 7 |
| 2 | Function of Ca^(2+)-/calmodulin-dependent protein kinase Ⅳ in Ca^(2+)-stimulated neuronal signaling and behavior显示文摘The activity of Ca2+/calmodulin-dependent protein kinase IV(Ca MKIV) is sensitive to activity-dependent changes in the level of intracellular Ca2+.Following neuronal stimulation,the activation of Ca MKIV may trigger synaptic modifications and transcriptional responses,both of which are involved in regulating cognitive and emotional behavior.Here,we used Ca MKIV knockout(KO) neurons and mice to examine the function of Ca MKIV in Ca2+-stimulated intracellular signaling and animal behavior,respectively.Following NMDA receptor activation or membrane depolarization,the up-regulation of CREB(c AMP responsive element binding protein) and its target gene Bdnf(brain-derived neurotrophic factor) was intact in cortical neurons obtained from Ca MKIV KO mice.Ca MKIV KO mice displayed severe impairment in contextual fear memory but normal locomotor activity and anxiety level in the contextual training chamber.Although Ca MKIV KO mice showed normal memory in the standard passive avoidance task,they were defective in learning the temporal dissociative passive avoidance task.As indicated by the light/dark test and marble-burying test data,Ca MKIV KO mice showed less anxiety and normal perseveration.In the voluntary wheel-running test,Ca MKIV KO mice showed normal running time and distance but higher maximal running speed.Our results demonstrate the function of Ca MKIV in regulating different forms of fear memory,anxiety,and certain aspect of motor function. | SONG ZiXiang CHEN Qi DING Qi ZHENG Fei LI ChengWei XU LePing WANG HongBing | 2015 | Science China(Life Sciences)2015，58，1： | 6 |
| 3 | High-throughput metagenomic analysis of petroleum-contaminated soil microbiome reveals the versatility in xenobiotic aromatics metabolism显示文摘The soil with petroleum contamination is one of the most studied soil ecosystems due to its rich microorganisms for hydrocarbon degradation and broad applications in bioremediation.However, our understanding of the genomic properties and functional traits of the soil microbiome is limited. In this study, we used high-throughput metagenomic sequencing to comprehensively study the microbial community from petroleum-contaminated soils near Tianjin Dagang oilfield in eastern China. The analysis reveals that the soil metagenome is characterized by high level of community diversity and metabolic versatility. The metageome community is predominated by γ-Proteobacteria and α-Proteobacteria, which are key players for petroleum hydrocarbon degradation. The functional study demonstrates over-represented enzyme groups and pathways involved in degradation of a broad set of xenobiotic aromatic compounds, including toluene, xylene, chlorobenzoate, aminobenzoate, DDT, methylnaphthalene, and bisphenol. A composite metabolic network is proposed for the identified pathways, thus consolidating our identification of the pathways. The overall data demonstrated the great potential of the studied soil microbiome in the xenobiotic aromatics degradation. The results not only establish a rich reservoir for novel enzyme discovery but also provide putative applications in bioremediation. | Yun-Juan Bao Zixiang Xu Yang Li Zhi Yao Jibin Sun Hui Song | 2017 | Journal of Environmental Sciences2017，29，6： | 5 |
| 4 | Distributed joint source-channel coding of video using raptor codes 显示文摘 | Qian Xu Vladimir Stankovi' c Zixiang Xiong | 2007 | IEEE Journal on Selected Areas in Co mmtmicafions2007，25，4： | 1 |
| 5 | Layered Wyner-Ziv video coding for transmission over unreliable channels显示文摘 | XU Qian STANKOVIC V XIONG Zixiang | 2006 | Signal Processing2006，86，11： | 1 |
| 6 | Layered Wyner-Ziv video coding 显示文摘 | Xu Qian Xion Zixiang | 2006 | IEEE Transactions on Image Processing2006，15，12： | 1 |
| 7 | Analysis of enhanced cur- rent-generating mechanism of geobacter sulfurreducens strain via model-&iven metabolism simulation 显示文摘 | MENG Jing XU Zixiang GUO Jing | 2013 | Plos One2013，8，9： | 1 |
| 8 | Layered Wyner-Ziv video coding for transmission over unreliable channels 显示文摘 | XU Qian STANKOVIC V XIONG Zixiang | 2006 | Signal Processing: Special Section on Distributed Source Coding2006，86，11： | 1 |
| 9 | Three-dimensional Embedded Subband Coding with Optimized Truncation(3-D ESCOT)显示文摘 | Xu Jizheng Xiong Zixiang Li Shipeng | | 0，，： | 1 |
| 10 | Layered Wyner-Ziv video coding 显示文摘 | Xu Qian Xiong Zixiang | 2006 | IEEE Transactoins on Image Processing2006，15，12： | 1 |
| 11 | Some extremal results on hypergraph Turán problems显示文摘For two r-graphs T and H,let ex_(r)(n,T,H)be the maximum number of copies of T in an n-vertex H r-graph.The determination of the Turán number ex_(r)(n,T,H)has become the fundamental core problem in extremal graph theory ever since the pioneering work of Turán’s theorem was published in 1941.Although we have some rich results for the simple graph case,only sporadic results have been known for the hypergraph Turán problems.In this paper,we mainly focus on the function ex_(r)(n,T,H)when H is one of two different hypergraph extensions of the complete bipartite graph K_(s,t).The first extension is the complete bipartite r-graph K^((r))_(s,t),which was introduced by Mubayi and Verstraëte(2004).Using the powerful random algebraic method,we show that if s is sufficiently larger than t,then ex_(r)(n,T,K^((r))_(s,t))=Ω(n^(v−e/t)),where T is an r-graph with v vertices and e edges.In particular,when T is an edge or some specified complete bipartite r-graph,we can determine their asymptotics.The second important extension is the complete r-partite r-graph K^((r))_(s1,s2,…,sr,)which has been widely studied.When r=3,we provide an explicit construction giving ex_(3)(n,K^((3))_(2,2,7))≥1/27n19/7+o(n19/7).Our construction is based on the norm graph,and improves the lower boundΩ(n73/27)obtained by the probabilistic method. | Zixiang Xu Tao Zhang Gennian Ge | 2022 | Science China Mathematics2022，65，8： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员