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| 1 | The influence of mechanical loading on osseointegration:an animal study显示文摘Osseointegration of implant provides a stable support for the prosthesis under functional loads.The timing of loading is a critical parameter that can govern the success of the osseointegration of implant.However,it is not clear whether the early loading can affect the success of osseointegration,or whether the no-loading healing period can be shortened.This paper presents an animal study conducted to investigate how external loads influence the osseointegration at the initial stage of healing.Titanium implants were inserted into the goat tibia laterally,and different axial loadings were applied to the im-plants in 4 weeks after surgery.After the 2 weeks period of early loading,animals were sacrificed and the tibia bones with the implants were cut off from the bodies.Then mechanical test was employed to find out the differences in the pull-out force,and shear strength at the bone-implant interface between the non-loaded and the loaded implants.The implant-bone interfaces were analyzed by histomor-phometric method,SEM(scanning electron micrograph) and EDS(energy density spectrum).The re-sults indicated that the bone-implant interface did not well integrate 4 weeks after surgery,and the fi-brous tissue could be found at the interfaces of the specimens without loadings.While the results of loaded specimens with 10 N axial force showed that that parts of the interface were well integrated,indicating that the early mild loading may play a positive role in the process of the osseointegration.The results support that a certain range of external loading would influence the process of osseointe-gration,and appropriate mechanical loading can be applied to shorten the osseointegration period after surgery. | FAN YuBo1,XIU KaiHua1,DONG Xiang2 & ZHANG Ming2 1 School of Biological Science and Medical Engineering,Beihang University,Beijing 100083,China 2 Department of Health Technology and Informatics,The Hong Kong Polytechnic University,Hong Kong,China | 2009 | Science China(Life Sciences)2009，52，6： | 3 |
| 2 | Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B显示文摘The crude enzyme (PH-1) isolated from Pseudostellaria heterophylla by our group has catalyzed enzymatic cyclization of linear peptide NH2-Gly1-Gly2-Leu-Pro-Pro-Pro-Ile-Phe-COOH (4) into cyclopeptide heterophyllin B (HB) from plant for the first time. To ensure this reaction, some ana-lytical methods including TLC, HPLC, MS, NMR, and 13C labeling were used to prove that the reaction of substrate 4 sharing residue of NH-Phe-Gly-CO was successful. | JIA Aiqun1, LI Xiang2, TAN Ninghua1, LIU Xiaozhu3, SHEN Yuemao1 & ZHOU Jun1 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Graduate Univer-sity of Chinese Academy of Sciences, Chinese Academy of Sciences, Kunming 650204, China 2. Chinese Peptide Co., Ltd, Hangzhou 310018, China 3. Southwest Forestry College, Kunming 650204, China | 2006 | Science China Chemistry2006，49，1： | 2 |
| 3 | Optimization of Extraction Methods for Genomic DNA in Eomecon chinantha Hance.显示文摘 | HU Xue-hua1 CHEN Xiang2 LIAO Xin-jun1 JU Jian-wen1 GUO Yong-jiu1 1. College of Life Science Jinggangshan University Jian Jiangxi 343009 China 2. Institute of Forestry Research Foshan Guangzhou 528222 China | 2010 | Medicinal Plant2010，，03： | 1 |
| 4 | GENERAL CHARACTER OF MULTISTAGES OFMETALLOGENESIS FOR MICRO-MESOTHERMAL GOLD DEPOSITS:EXAMPLES FROM ZHANG-BALING TECTONIC BELT,ANHUI,CHINA显示文摘In Zhangbaling Tectonic Belt,two types of mineralization,auriferous quartz veins and alter- ation halos,can observed within many deposits.The pressure of metallogenesis of auriferous al- teration halos ismuch higher than thatof quartz vein,thetemperatures ofmetallogeneses ofthese two types of orebodies are don’tthe same Geochemistry study indicates thatboth ofthem are mi- cro- mesothermal deposits related to Yanshanian granites.The results of proton microprobe analy- sis of sulphides from the gold deposits in the area show that the“invisible” gold existed in sul- phides is in the form ofmicro inclusions,and the concentration of“invisible” gold in sulphidemin- erals within quartz vein is poorerthan thatfrom alteration halos.Field observation shows thatthe structural modality of the fractures controlling the orebodies of auriferous quartz vein is different from thatof the auriferous alteration zones.The fracture controlling the orebodies of auriferous alteration halos is compress- shearfracture,auriferous quartzvein is controlled by extensive fault. The alteration halos crosscut by auriferous quartz vein.The wallrocks of the former altered strongly and developed alteration zones well.The wallrocks of auriferous quartz vein altered slightly.The results of tectonogeochemical study shows that the concentration of associated met- allogenesis elements and intensity of alteration are positively correlated with tectonic deformation strength for auriferous alteration halos.Itindicates that it is probably a general character for mi- cro- mesothermal gold deposits due to the multistages of metallogeneses took place.The tectonic environmentis the most important fact determining the mechanism of fluid flow and precipitationof gold,and then the types of mineralization and modes of gold. | DAI Ta-gen1,HUANG De-zhi1,QIU Rui-long2 ,XU Xiang2 (1.College of Resource,Environment and Civil Engineering,Central South University, Changsha 410 0 83,China 2 .Anhui Institute of Geological Sciences,H efei 2 30 0 0 1,China) | 2001 | Geotectonica et Metallogenia2001，25，1： | 0 |
| 5 | X(3872) and Bound State Problem of D^0*~0(~0 D*~0)显示文摘We have performed a dynamical calculation of the bound state problem of D0D*0 by considering the pion and sigma meson exchange potential. Our preliminary analysis disfavors the molecular interpretation of X(3872) if we use the experimental D*Dπ coupling constant g=0.59 and a reasonable cutoff around 1 GeV,which is the typical hadronic scale. In contrast,there probably exists a loosely bound S-wave BB* molecular state. Such a molecular state would be rather stable since its dominant decay mode is the radiative decay through B*→Bγ. | LIU Yan-rui1,LIU Xiang2,3,DENG Wei-zhen2 (1 Institute of High Energy Physics,Chinese Academy of Sciences,Beijing 100049,China 2 Department of Physics,Peking University,Beijing 100871,China 3 Centro de Física Terica,Departamento de Física,Universidade de Coimbra,P-3004-516,Coimbra,Portugal) | 2009 | 原子核物理评论2009，26，S1： | 0 |
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