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| 1 | Red and Blue Lights Significantly Affect Photosynthetic Properties and Ultrastructure of Mesophyll Cells in Senescing Grape Leaves显示文摘Light quality significantly affects photosynthetic efficiency in plants. The mechanisms for how light quality affects photosynthesis in grape is poorly understood. Therefore, to investigate the effects of different light qualities on chloroplast ultrastructure and photosynthesis efficiency, two grape cultivars ‘Italia'(slower speed of leaf senescence) and ‘Centennial Seedless'(faster speed of leaf senescence) grown under protected and delayed conditions were used. The three treatments, replicated three times, were control(no supplemental lighting), red light and blue light. Chlorophyll content, net photosynthetic rate, and the ratio of F_v/F_m significantly increased in red light relative to the control. The opposite trend was observed in blue light in the early phase of leaf senescence. At later stages, physiological indexes were gradually higher than that of control, resulting in a delay in leaf senescence. Compared to the control, red and blue light both significantly increased the chlorophyll a/b ratio. Electron microscopy showed that blue light caused severe damage to the fine structure of chloroplasts at early stages of leaf senescence, but effects at later stages of leaf senescence became less severe compared to the control. The degradation of chloroplast ultrastructure was apparently delayed in red light throughout the experimental timeframe compared to other treatments. In this experiment, ‘Italia' showed higher chlorophyll content, net photosynthetic rate, ratios of F_v/F_m, chlorophyll a/b and better preserved chloroplast ultrastructure relative to ‘Centennial Seedless', resulting in a slower rate of leaf senescence. | WANG Shuai WANG Xiaodi SHI Xiangbin WANG Baoliang ZHENG Xiaocui WANG Haibo LIU Fengzhi | 2016 | Horticultural Plant Journal2016，2，2： | 10 |
| 2 | Influence of environmental factors on land-surface water and heat exchange during dry and wet periods in the growing season of semiarid grassland on the Loess Plateau显示文摘On the basis of information from the project 'Land-surface Processes and their Experimental Study on the Chinese Loess Plateau', we analyzed differences in land-surface water and heat processes during the main dry and wet periods of the semiarid grassland growing season in Yuzhong County, as well as the influences of these environmental factors. Studies have shown that there are significant differences in changes of land-surface temperature and humidity during dry and wet periods. Daily average normalized temperature has an overall vertical distribution of 'forward tilting' and 'backward tilting' during dry and wet periods, respectively. During the dry period, shallow soil above 20-cm depth is the active temperature layer. The heat transfer rate in soil is obviously different during dry and wet periods. During the dry period, the ratio of sensible heat flux to net radiation(H/Rn) and the value of latent heat flux to net radiation(LE/Rn) have a linear relationship with 5-cm soil temperature; during the wet period, these have a nonlinear relationship with 5-cm soil temperature, and soil temperature of 16°C is the critical temperature for changes in the land-surface water and heat exchange trend on a daily scale. During the dry period, H/Rn and LE/Rn have a linear relationship with soil water content. During the wet period, these have a nonlinear relationship with 5-cm soil water content, and 0.21 m3 m?3 is the critical point for changes in the land-surface water and heat exchange trend at daily scale. During the dry period, for vapor pressure deficit less than 0.7 k Pa, H/Rn rises with increased vapor pressure deficit, whereas LE/Rn decreases with that increase. When that deficit is greater than 0.7 k Pa, both H/Rn and LE/Rn tend to be constant. During the wet period, H/Rn increases with the vapor pressure deficit, whereas LE/Rn decreases. The above characteristics directly reflect the effect of differences in land-surface environmental factors during land-surface water and heat exchange processes, and indirectly reflect the influences of cloud precipitation processes on those processes. | YUE Ping ZHANG Qiang ZHAO Wen WANG RunYuan ZHANG Liang WANG WenYu SHI JinSen HAO XiaoCui | 2015 | Science China Earth Sciences2015，58，11： | 6 |
| 3 | Bioaccumulation and the expression of hepatic cytochrome P450 genes in marine medaka(Oryzias melastigma)exposed to difenoconazole显示文摘This study was conducted to assess the effects of difenoconazole(DFZ), a triazole fungicide,on the hepatic biotransformation system and its bioaccumulation in marine medaka(Oryzias melastigma). Fish were exposed to DFZ(1, 10, 100, 1000 ng/L) for 180 days. The results showed that:(1) The m RNA levels of hepatic CYP1A1, CYP1 B, CYP1C1, CYP27 B and CYP3A40 were up-regulated, but those of CYP3A38 and CYP27A1 were down-regulated.(2) The activity of ethoxyresorufin-O-deethylase(EROD) and the content of reduced glutathione(GSH) in the liver were increased in the DFZ-treated groups, and glutathione S-transferase(GST) activity was increased in the 100 and 1000 ng/L groups.(3) DFZ was accumulated in the muscle and the biological concentration factors in the 10, 100, and1000 ng/L groups were respectively 149, 81 and 25. These results suggested that long-term exposure to DFZ at low concentrations would result in a bioaccumulation of this compound and disturb the biotransformation system. | Lemeng Zhang Xiaocui Dong Chonggang Wang Zhenghong Zuo Meng Chen | 2017 | Journal of Environmental Sciences2017，29，2： | 5 |
| 4 | Glycyrrhetinic acid-modified nanoparticles for drug delivery: Preparation and characterization显示文摘In this work, glycyrrhetinic acid-modified chitosan (mGA-suc-CTS) used as liver targeted carrier for drug delivery, was prepared via hemisuccinate as a bridged group. The structure of the product was confirmed by IR and NMR methods and the degree of substitution (DS) of glycyrrhetinic acid groups was estimated via elemental analysis. Nanoparticles were formed by ionic gelation methold. The drug-loading and release behavior of the nanoparticles were investigated using BSA as the model drug. The results indicated that the carrier with a highest DS of 5.19% could be got and the DS was controlled by changing reaction temperature or feed ratio. BSA could be entrapped into the nanoparticles with the drug-loading ratio of 26.3% and the encapsulation efficiency of 81.5%. A sustained release over an 11-day period was observed in pH 7.4 in vitro. | TIAN Qin WANG Wei HE XiaoTing ZHU XiaoCui HUANG Wei ZHANG ChuangNian YUAN Zhi CHEN XueSi | 2009 | Chinese Science Bulletin2009，54，18： | 4 |
| 5 | Exposure to difenoconazole inhibits reproductive ability in male marine medaka(Oryzias melastigma)显示文摘Difenoconazole(DFZ) is a triazole fungicide which has been detected in the aquatic environment, including estuaries and embayments. However, few studies addressing the reproductive toxicity and transgenerational effects of DFZ on marine fishes are available.The present study was conducted to investigate the effects of DFZ on male marine medaka(Oryzias melastigma). After exposure of the embryo to 1, 10, 100 and 1000 ng/L DFZ for180 days, the gonadosomatic index was significantly decreased in the 1000 ng/L treatment.The number of sperm was reduced while the abundances of spermatocytes and spermatogonia in the testes were increased in all the treatments. The m RNA levels of salmontype gnrh(sgnrh), the luteinizing hormone(lhβ) and the follicle-stimulating hormone(fshβ)genes in the brain all exhibited a significant down-regulation, the expression of androgen receptors(arα and arβ) was decreased and that of estrogen receptor β and cytochrome P450 aromatase(cyp19 B) was increased in the testes. The expression levels of cyp19 A and cyp19 B were increased in the liver. The decrease of ars m RNA levels might be one of the reasons causing the reduction of sperm. The down-regulation of sgnrh, lhβ and fshβ m RNA levels suggested that DFZ might impact the spermatogenesis via the brain–pituitary–gonad pathway. The decrease of the fertilization success, the hatch ability and the swim-up success in the F1 generation indicated that DFZ pollution at environmental levels might cause a decrease of wild fish populations. | Xiaocui Dong Lemeng Zhang Meng Chen Zhibin Yang Zhenghong Zuo Chonggang Wang | 2018 | Journal of Environmental Sciences2018，30，1： | 3 |
| 6 | Formation process and mechanism of humic acid-kaolin complex determined by carbamazepine sorption experiments and various characterization methods显示文摘To explore the formation process and mechanism of organic matter and organic-mineral complex under humification and mineralization conditions, a series of samples including humic acid, kaolin, and humic acid-kaolin complex were prepared using a subcritical water treatment method(SWT) under specific temperature, pressure and reaction time conditions. HA was used as a surrogate for natural organic matter because it has a similar abundant pore structure,variety of carbon types, and chemical components. These samples were used in carbamazepine(CBZ) sorption experiments and characterized by a variety of techniques. The polymerization of humic acid under the conditions of increased temperature and pressure resulted in an increase in specific surface area and molecular quantity. In addition, the degree of aromaticity rose from59.52% to 70.90%. These changes were consistent with the transformation from ‘soft carbon' to‘hard carbon' that occurs in nature. The results of sorption experiments confirmed the interaction between humic acid and kaolin from the difference between the predicted and actual Qevalues. The conceptual model of humic acid-kaolin complex could be deduced and described as follows. Firstly, the aromatic components of humic acid preferentially combine with kaolin through the intercalation effect, which protects them from the treatment effects.Next, the free carboxyl groups and small aliphatic components of humic acid interact on the surface of kaolin, and these soft species transform into dense carbon through cyclization and polymerization. As a result, humic acid-kaolin complex with a mineral core and dense outer carbonaceous patches were formed. | Fei Wang Jiangtao He Baonan He Xiaojing Zhu Xiaocui Qiao Liuyue Peng | 2018 | Journal of Environmental Sciences2018，30，7： | 3 |
| 7 | Effect of dietary protein sources and storage temperatures on egg internal quality of stored shell eggs显示文摘This study was conducted to evaluate the effects of various protein sources(soybean meal, SBM; cottonseed protein, CSP; double-zero rapeseed meal, DRM) on the internal quality(Haugh unit, yolk index,albumen pH,yolk hardness and yolk springiness) of eggs when stored at either 4 or 28℃ for 28 d. A total of 288 laying hens(32 wk of age) were randomly allotted to 6 treatment groups(4 replicates per treatment) and fed diets containing SBM, CSP, or DRM individually or in combination with equal crude protein content(SBM-CSP, SBM-DRM, and CSP-DRM) as the protein ingredient(s). A 6 x 2 factorial arrangement was employed with dietary types and storage temperatures(4 and 28℃) as the main effects. After 12 wk of diet feeding, a total of 216 eggs was collected for egg internal quality determination.The results showed as follows: 1) lower egg quality was observed in the DRM group compared with the other groups when stored at 4 and 28℃ for 28 d(P < 0.05), while there was no difference in egg internal quality among the other groups. 2) The CSP diet resulted in higher yolk hardness compared with the other diets when eggs were stored at 4℃ for 28 d(P < 0.05). Lower Haugh unit was observed in the DRM and SBM-DRM groups compared with the other groups when eggs were stored for 28 d at 4℃(P < 0.05).3) Yolk breakage occurred in the DRM group and eggs could not be analyzed for egg internal quality when stored at 28℃ for 28 d. The overall results indicated that CSP or DRM as the sole dietary protein source for laying hens may adversely affect the internal quality of stored eggs as compared with the SBM diet, and half replacement of CSP combined with SBM may maintain similar egg quality to SBM diet alone for eggs stored under refrigerated conditions. | Xiaocui Wang Shugeng Wu Haijun Zhang Hongyuan Yue Guanghai Qi Jie Li | 2015 | Animal Nutrition2015，，4： | 3 |
| 8 | Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis显示文摘Major evolutionary transitions are enigmas,and the most notable enigma is between invertebrates and vertebrates,with numerous spectacular innovations.To search for the molecular connections involved,we asked whether global epigenetic changes may offer a clue by surveying the inheritance and reprogramming of parental DNA methylation across metazoans.We focused on gametes and early embryos,where the methylomes are known to evolve divergently between fish and mammals.Here,we find that methylome reprogramming during embryogenesis occurs neither in pre-bilaterians such as cnidarians nor in protostomes such as insects,but clearly presents in deuterostomes such as echinoderms and invertebrate chordates,and then becomes more evident in vertebrates.Functional association analysis suggests that DNA methylation reprogramming is associated with development,reproduction and adaptive immunity for vertebrates,but not for invertebrates.Interestingly,the single HOX cluster of invertebrates maintains unmethylated status in all stages examined.In contrast,the multiple HOX clusters show dramatic dynamics of DNA methylation during vertebrate embryogenesis.Notably,the methylation dynamics of HOX clusters are associated with their spatiotemporal expression in mammals.Our study reveals that DNA methylation reprogramming has evolved dramatically during animal evolution,especially after the evolutionary transitions from invertebrates to vertebrates,and then to mammals. | Xiaocui Xu Guoqiang Li Congru Li Jing Zhang Qiang Wang David KSimmons Xuepeng Chen Naveen Wijesena Wei Zhu Zhanyang Wang Zhenhua Wang Bao Ju Weimin Ci Xuemei Lu Daqi Yu Qian-fei Wang Neelakanteswar Aluru Paola Oliveri Yong EZhang Mark QMartindale Jiang Liu | 2019 | National Science Review2019，6，5： | 2 |
| 9 | Coupling between the Grain for Green Program and a household level-based agricultural eco-economic system in Ansai,Shaanxi Province of China显示文摘The implementation of the Grain for Green Program(GGP)has changed the development track of the agricultural eco-economic system in China.In response to the results of a lag study that investigated the coupling between the GGP and the agricultural eco-economic system in a loess hilly region,we used a structural equation model to analyze the survey data from 494 households in Ansai,a district of Yan’an City in Shaanxi Province of China in 2015.The model clarified the direction and intensity of the coupling between the GGP and the agricultural eco-economic system.The coupling benefits were derived through linkages between the program and various chains in the agricultural eco-economic system.The GGP,the agroecosystem of Ansai and their potential coupling effects were in a state of general coordination.The agroecosystem directly affected the coupling effect,with the standardized path coefficient of 0.87,indicating that the agroecosystem in Ansai at this stage provided basic material support for the coupling between the GGP and the agricultural eco-economic system.The direct path coefficient of agroeconomic system impacted on the coupling effect was-0.76,indicating that partial contradictions occurred between the agroeconomic system and the coupling effect.Therefore,although the current agroecosystem in Ansai should be provided sufficient agroecological resources for the benign coupling between the program and the agricultural eco-economic system,agricultural development failed to effectively transform agroecological resources into agricultural economic advantages in this region,which resulted in a relative lag in the development of the agricultural economic system.Thus,the coupling between the GGP and the agricultural eco-economic system was poor.To improve the coupling and the sustainable development of the agricultural eco-economic system in cropland retirement areas,the industrial structure needs to be diversified,the agricultural resources(including agroecological resources,agricultural economic resources and agricultural social resources)need to be rationally allocated,and the chain structure of the agricultural eco-economic system needs to be continuously improved. | LI Yue WANG Jijun HAN Xiaojia GUO Mancai CHENG Simin QIAO Mei ZHAO Xiaocui | 2020 | Journal of Arid Land2020，12，2： | 2 |
| 10 | Accurate annotation of accessible chromatin in mouse and human primordial germ cells显示文摘广泛、精确的染色质改变在初发的细菌房间(PGC ) 期间是必要的为越过代的基因信息的永存的开发。这里,我们报导 DNase 我过分敏感的地点(DHS ) 标记的远侧的 cis 规章的元素(CRE ) 在鼠标和人的 PGC 开发期间显示出时间地限制的活动。把 DHS 地图用作代理,我们精确地在老鼠 PGC 定位 pluripotency 抄写因素的染色体宽的有约束力的地点。出人意料地,我们发现老鼠女性 meiotic 再结合热点能被 DHS 捕获,并且第一次,我们在老鼠女性 PGC 识别了 12,211 个再结合热点。与 meiotic 女性 PGC 的相对照,有丝分裂拘捕的男 PGC 的染色质 ? 通过在远侧的规章的区域的原子抄写因素 Y (NFY ) 绑定是容许的。而且,我们在 PGC CRE 上检验了进化压力,并且比较 genomic 分析表明那只老鼠和人的 PGC CRE evolutionarily 在哺乳动物外面越过脊椎动物树被保存并且出现强壮的保存。因此,我们的结果在鼠标和人的 PGC 开发期间揭示唯一的、时间地可存取的染色质配置。 | Jingyi Li Shijun Shen Jiayu Chen Wenqiang Liu Xiaocui Li Qianshu Zhu Beiying Wang Xiaolong Chen Li Wu Mingzhu Wang Liang Gu Hong Wang Jiqing Yin Cizhong Jiang Shaorong Gao | 2018 | Cell Research2018，28，11： | 2 |
| 11 | Experiment and numerical simulation on the characteristics of fluid–structure interactions of non-rigid airships显示文摘Fluid–structure interaction is an important issue for non-rigid airships with inflated envelopes. In this study, a wind tunnel test is conducted, and a loosely coupled procedure is correspondingly established for numerical simulation based on computational fluid dynamics and nonlinear finite element analysis methods. The typical results of the numerical simulation and wind tunnel experiment, including the overall lift and deformation, are in good agreement with each other. The results obtained indicate that the effect of fluid–structure interaction is noticeable and should be considered for non-rigid airships. Flowinduced deformation can further intensify the upward lift force and pitching moment, which can lead to a large deformation. Under a wind speed of 15 m/s, the lift force of the non-rigid model is increased to approximately 60% compared with that of the rigid model under a high angle of attack. | Xiaocui Wu Yiwei Wang Chenguang Huang Yubiao Liu Lingling Lu | 2015 | Theoretical & Applied Mechanics Letters2015，5，6： | 1 |
| 12 | Discovering the relationship of disasters from big scholar and social media news datasets显示文摘The construction method for chains of disasters or events is still one of the core scientific questions in studying the common rules of disaster’s evolution.Especially when dealing with the complexity and diversity of disasters,it is critical to make a further investigation on reducing the dependency of prior knowledge and supporting the comprehensive chains of disasters.This paper tries to propose a novel approach,through collecting the big scholar and social news data with disasterrelated keywords,analysing the strength of their relationships with the co-word analysis method,and constructing a complex network of all defined disaster types,in order to finally intelligently extract the unique disaster chain of a specific disaster type.Google Scholar,Baidu Scholar and Sina News search engines are employed to acquire the needed data,and the respectively obtained disaster chains are compared with each other to show the robustness of our proposed approach.The achieved disaster chains are also compared with the ones concluded from existing research methods,and the very reasonable result is demonstrated.There is a great potential to apply this novel method in disaster management domain to find more secrets about disasters. | Liang Zheng Fei Wang Xiaocui Zheng Binbin Liu | 2019 | International Journal of Digital Earth2019，12，11： | 1 |
| 13 | The activation of Caspase显示文摘 | WANG Xiaobing ZHANG Xiaocui XIA Miaohong | | 0，，03： | 1 |
| 14 | Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7显示文摘Dear Editor,The COVID-19 pandemic caused by SARS-CoV-2 has led to acute respiratory distress syndrome(ARDS)with a high rate of death.An excessive inflammatory response,caused by virus infection,is associated with severe clinical manifestations that may lead to death of patients.1 Therefore,the blockage of virus replication and suppression of hyper-inflammatory response are beneficial for COVID-19 treatment.However,the drug targeting both virus and hyper-inflammation,as far as we know,is not available yet. | Chen Xie Yanlian Chen Dongling Luo Zhen Zhuang Heping Jin Haoxian Zhou Xiaocui Li Haijun Lin Xiaohui Zheng Jing Zhang Peihui Wang Jincun Zhao Yong Zhao Hui Huang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 15 | Gray matter volume abnormalities in individuals with cognitive vulnerability to depression: A voxel-based morphometry study显示文摘 | Xiaocui Zhang Shuqiao Yao Xiongzhao Zhu Xiang Wang Xueling Zhu Mingtian Zhong | 2011 | Journal of Affective Disorders2011，，3： | 1 |
| 16 | Improved integral sliding mode control methods for speed control of PMSM system显示文摘 | Xia Cunjian Wang Xiaocui Li Shihua | 2011 | International Journal of Innovative Computing Information and Control2011，7，4： | 1 |
| 17 | Improved integral sliding mode control methods for speed control of PMSM system显示文摘 | Wang Xiaocui Li Shihua Chen Xisong | 2011 | International Journal of Innovative Computing Information and Control2011，7，4： | 1 |
| 18 | An effective inducer of dopaminergic neuron-like differentiation显示文摘Rat bone marrow-derived mesenchymal stem cells were cultured and passaged in vitro. After induction with basic fibroblast growth factor for 24 hours, passage 3 bone marrow-derived mesenchymal stem cells were additionally induced into dopaminergic neurons using three different combinations with basic fibroblast growth factor as follows: 20% Xiangdan injection; all-trans retinoic acid + glial-derived neurotrophic factor; or sonic hedgehog + fibroblast growth factor 8. Results suggest that the bone marrow-derived mesenchymal stem cells showed typical neuronal morphological characteristics after induction. In particular, after treatment with sonic hedgehog + fibroblast growth factor 8, the expressions of nestin, neuron-specific enolase, microtubule- associated protein 2, tyrosine hydroxylase and vesicular monoamine transporter-2 in cells were significantly increased. Moreover, the levels of catecholamines in the culture supernatant were significantly increased. These findings indicate that Xiangdan injection, all-trans retinoic acid + glial-derived neurotrophic factor, and sonic hedgehog + fibroblast growth factor 8 can all induce dopaminergic neuronal differentiation from bone marrow-derived mesenchymal stem cells. In particular, the efficiency of sonic hedgehog + fibroblast growth factor 8 was highest. | Wenyu Fu Cui Lv Wenxin Zhuang Dandan Chen E Lv Fengjie Li Xiaocui Wang | 2013 | Neural Regeneration Research2013，8，5： | 1 |
| 19 | Gray matter volume abnormalities in individuals with cognitive vulnerability to depression: A voxel-based morphometry study显示文摘 | Xiaocui Zhang Shuqiao Yao Xiongzhao Zhu Xiang Wang Xueling Zhu Mingtian Zhong | 2011 | Journal of Affective Disorders2011，，3： | 1 |
| 20 | An overview on observational instruments and measuring methods for dewfall显示文摘This paper systematically summarizes previous measuring methods and observational instruments for the magnitude of dewfall on land surface,analyzes the characteristics of common observational instruments for land surface dewfall,and describes several ba-sic dewfall measurement methods.Moreover,the basic principles of these methods and instruments are interpreted,and their ad-vantages,disadvantages,and applicability are analyzed.Recommendations for the further improvement of these observational in-struments and the development of dewfall measuring methods are presented,and new technologies and scientific proposals for exploiting dewfall are elucidated. | Qiang Zhang XiaoCui Hao XiaoMei Wen Sheng Wang Jian Zeng | 2011 | Research in Cold and Arid Regions2011，3，1： | 1 |
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