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1703篇 您的检索式:作者名="Xing W"
    题名 作者 年代 出处 被引量
1Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis显示文摘Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen DC Liu J Tao TZ Wu W 2014Chinese Medical Journal2014,,4:16
2Novel DNA vaccine based on hepatitis B virus core gene induces specific immune responses in Balb/c mice显示文摘AIM: To investigate the immunogenicity of a novel DNA vaccine,pSW3891/HBc, based on HBV core gene in Balb/c mice.METHODS: A novel DNA vaccine, pSW3891/HBc, encoding HBV core gene was constructed using a vector plasmid pSW3891. Balb/c mice were immunized with either pSW3891/HBc or empty vector DNA via gene gun. IgG anti-HBc responses in mouse sera were demonstrated by ELISA. Specific cytotoxicity of cytotoxic T lymphocytes (CTLs) of mice was quantitatively measured by lactate dehydrogenase release assay.RESULTS: HBcAg was expressed effectively in 293T cell line transiently transfected with pSW3891/HBc. Strong IgG anti-HBc responses were elicited in mice immunized with pSW3891/HBc. The end-point titers of anti-HBc reached the highest 1:97 200, 4 wk after the third immunization. The specific CTL killing with the highest specific lysis reached 73.25% at effector:target ratio of 20:1 in mice that received pSW3891/HBc DNA vaccine.CONCLUSION: pSW3891/HBc vaccination elicits specific anti-HBc response and induces HBc-specific CTL response in immunized Balb/c mice.Yi-Ping Xing Zu-Hu Huang Shi-Xia Wang Jie Cai Jun Li Te-Hui W Chou Shan Lu 2005World Journal of Gastroenterology2005,11,29:7
3Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis显示文摘To assess the utility of longitudinal ultrasound(US) to quantify volumetric changes in joint soft tissues during the progression of posttraumatic osteoarthritis(PTOA) in mice, and validate the US results with histological findings. A longitudinal cohort of 3-month-old wild-type C57 BL/6 male mice received the Hulth-Telhag surgical procedure on right knee to induce PTOA, and sham surgery on their left knee as control. US scans were performed on both knees before, 2, 4, 6, and 8 weeks post-surgery. Joint space volume and Power-Doppler(PD) volume were obtained from US images via Amira software. A parallel cross-sectional cohort of mice was killed at each US time point, and knee joints were subjected to histological analysis to obtain synovial soft-tissue area and OARSI scores. The correlation between US joint space volume and histological synovial soft-tissue area or OARSI score was assessed via linear regression analysis. US images indicated increased joint space volume in PTOA joints over time, which was associated with synovial inflammation and cartilage damage by histology. These changes started from 2 weeks post-surgery and gradually became more severe. No change was detected in sham joints. Increased joint space volume was significantly correlated with increased synovial soft-tissue area and the OARSI score(P o 0.001). PD signal was detected in the joint space of PTOA joints at 6 weeks post-surgery, which was consistent with the location of blood vessels that stained positively for CD31 and alpha-smooth muscle actin in the synovium.This study indicates that US is a cost-effective longitudinal outcome measure of volumetric and vascular changes in joint soft tissues during PTOA progression in mice, which positively correlates with synovial inflammation and cartilage damage.Hao Xu Echoe M Bouta Ronald W Wood Edward M Schwarz Yongjun Wang Lianping Xing 2017Bone Research2017,5,3:7
4A new Early Cretaceous dinosaur track assemblage and the first definite non-avian theropod swim trackway from China显示文摘The trackway of a swimming theropod (ichnogenus Characichnos) is reported from the Lower Cretaceous Feitianshan Formation of Sichuan, China. These swim tracks help confirm that non-avian theropods were capable of forging moderately deep bodies of water. The trackway occurs on the same surface as a typical walking trackway of a sauropod (ichnogenus Brontopodus). Both occurrences are the first reported from the Cretaceous of Sichuan, and the swim tracks are the first well-preserved example of a Characichnos trackway from China. Additionally, a theropod walking trackway and several ornithopod walking trackways (similar to the ichnogenus Caririchnium) occur in the same horizon. The ornithopod trackways show a parallel orientation, suggesting gregarious behavior of the trackmakers, which may have been iguanodontiforms and/or hadrosauriforms. The co-occurrence of theropod swim tracks and theropod walking tracks suggests a fluctuation of water depth within a distinct time span.XING LiDa LOCKLEY Martin G ZHANG JianPing MILNER Andrew R C KLEIN Hendrik LI DaQing PERSONS IV W Scott EBI JieFang 2013Chinese Science Bulletin2013,58,19:3
5Susceptibility to gastric cardia adenocarcinomaandgenetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population显示文摘Miao XP Xing DY Tan W 2002Cancer Epi Bio Prev2002,11,:2
6Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population 显示文摘Song C Xing D Tan W 2001Cancer Res2001,61,:2
7Study of irreversible capacities for Li insertion in hard and graphitic carbons显示文摘Xing W Dahn J R 1997J Electrochemical Society1997,144,4:1
8Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population显示文摘Miao X Xing D Tan W 2002Cancer Epidemiol Biomarkers Prev2002,11,11:1
9Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors 显示文摘MAEKAWA A KANAOKA Y XING W et ol 2008Proc Natl Acad Sci USA2008,105,16:1
10Time-frequency imaging algorithm for high speed spinning targets in two dis- mensions 显示文摘Li J Qiu C W Xing M D Bao Z Yeo T S 2010lET2010,4,6:1
11A checklist of vascular plantsfound in Fungshui woods in Hong Kong 显示文摘CHU W H XING Fu-wu 1997Mem HongKong Nat Hist Soc1997,21,:1
12Overexpression of activated nuclear factor-k B in aorta of patients with coro- nary atherosclerosis 显示文摘Zhang W Xing S S Sun X L 2009Clin Cardiol2009,32,12:1
13Direct association of hepatopoietin with thioredoxin constitutes a redox signaltransduction in activation of AP-1/NF-kappaB 显示文摘Li Y Liu W Xing G 2005Cell Signal2005,17,8:1
14UV-curable functionalized graphene oxide/polyurethane acrylate nanocomposite coatings with enhanced thermal stability and mechanical properties显示文摘YU B WANG X XING W Y 2012Industrial & Engineering Chemistry Research2012,51,14:1
15查看详情显示文摘Shi D H Xing W Sun J F Zhu Z L Liu Y F 0,,:1
16Evaluation of the esthetic effect of resin cements and try-in pastes on ceromer veneers显示文摘Xing W Jiang T Ma X 2010J Dent2010,382,:1
17Knockdown of RLIP76 expression by RNA interference inhibits proliferation, enhances apoptosis, and increases chemosensitivity to daunorubicin in U937 leukemia cells显示文摘Yao K Xing H Yang W Liao A Wu B Li Y 2014Tumour Biol2014,35,:1
18Adsorption of phosphate from aqueous solutions onto modified wheat residue; characteristics, kinetic and column studies显示文摘Xing X Baoyu G Wenyi W 2009Colloids and Surfaces B: Biointerfaces2009,,70:1
19Towards mo- bile intelligence: learning from GPS history data for col- laborative recommendation 显示文摘Zheng V W Zheng Yu Xie Xing 2012Artificial Intelligence2012,184,6:1
20A new way of designing bulk metallic glasses in Cu-Ti-Zr-Ni system显示文摘Yang Y J Xing D W Li C P 2007Materials Science and Engineering A2007,448,:1
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