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| 1 | Photonic matrix multiplication lights up photonicaccelerator and beyond显示文摘Matrix computation,as a fundamental building block of information processing in science and technology,contributes most of the computational overheads in modern signal processing and artificial intelligence algorithms.Photonic accelerators are designed to accelerate specific categories of computing in the optical domain,especially matrix multiplication,to address the growing demand for computing resources and capacity.Photonic matrix multiplication has much potential to expand the domain of telecommunication,and artificial intelligence benefiting from its superior performance.Recent research in photonic matrix multiplication has flourished and may provide opportunities to develop applications that are unachievable at present by conventional electronic processors.In this review,we first introduce the methods of photonic matrix multiplication,mainly including the plane light conversion method,Mach–Zehnder interferometer method and wavelength division multiplexing method.We also summarize the developmental milestones of photonic matrix multiplication and the related applications.Then,we review their detailed advances in applications to optical signal processing and artificial neural networks in recent years.Finally,we comment on the challenges and perspectives of photonic matrix multiplication and photonic acceleration. | Hailong Zhou Jianji Dong Junwei Cheng Wenchan Dong Chaoran Huang Yichen Shen Qiming Zhang Min Gu Chao Qian Hongsheng Chen Zhichao Ruan Xinliang Zhang | 2022 | Light(Science & Applications)2022，11，2： | 4 |
| 2 | Lattice Bohzmann simulation of flow in a micro-channel显示文摘 | Zhang Renliang Di Qinfeng Wang Xinliang Gu Chunyuan Wang Wenchang | 2011 | Chinese J Comput Phys2011，28，2： | 1 |
| 3 | Macrophages in Ischemic Heart Failure:Yesterday,Today,and Tomorrow显示文摘With continually improving reperfusion strategies and patient care,the overall mortality of acute myocardial infarction(AMI)has been significantly reduced during the past two decades.However,this success is a double-edged sword,as many patients surviving an AMI will progress towards ischemic heart failure(HF)over time.The pathologic causes of ischemic HF are undoubtedly multifactorial.However,the inflammatory response is considered one of the most important causes of pathological remodeling because it spans the whole process of HF development.The macrophage-mediated inflammatory response was once considered a purely harmful factor leading to pathological remodeling and HF.However,growing evidence demonstrates that multiple subgroups of macrophage exist and contribute differently to ischemic HF development.Understanding macrophage populations and how they contribute to post-MI remodeling and consequent ischemic HF is,therefore,critical to understanding and treating the disease.This review focuses on different macrophage populations that regulate post-MI cardiac injury and how immunoregulation therapy may benefit patients with ischemic HF. | Demin Liu Wenjun Yan Jingwen Huang Jianli Zhao Houston Kilby Theodore AChristopher Bernard Lopez Ling Tao Xinliang Ma Guoqiang Gu Yajing Wang | 2021 | Cardiology Discovery2021，1，2： | 0 |
| 4 | On-chip photonic spatial-temporal descrambler显示文摘As an indispensable part to compensate for the signal crosstalk in fiber communication systems,conventional digital multi-input multi-output(MIMO)signal processor is facing the challenges of high com-putational complexity,high power consumption and relatively low processing speed.The optical MIMOenables the best use of light and has been proposed to remedy this limitation.However,the currently existing optical MIMO methods are all restricted to the spatial di-mension,while the temporal dimension is neglected.Here,an on-chip spatial-temporal descrambler with four channels were devised and its MIMO functions were experimentally verified simultaneously in both spatial and temporal dimensions.The spatial crosstalk of single-channel descrambler and four-channel descrambler is respectively less than-21 dB and-18 dB,and the time delay is simultaneously com-pensated successfully.Moreover,a more universal model extended to mode-dependent loss and gain(MDL)compensation was further de-veloped,which is capable of being cascaded for the real optical trans-mission system.The first attempt at photonic spatial-temporal de-scrambler enriched the varieties of optical MIMO,and the proposed scheme provided a new opportunity for all-optical MIMO signal pro-cessing. | Wenkai Zhang Xueyi Jiang Wentao Gu Junwei Cheng Hailong Zhou Jianji Dong Dongmei Huang Xinliang Zhang | 2023 | Chip2023，2，2： | 0 |
| 5 | Multiple regulatory roles of the transfer RNA-derived small RNAs in cancers显示文摘With the development of sequencing technology,transfer RNA(tRNA)-derived small RNAs(tsRNAs)have received extensive attention as a new type of small noncoding RNAs.Based on the differences in the cleavage sites of nucleases on tRNAs,tsRNAs can be divided into two categories,tRNA halves(tiRNAs)and tRNA-derived fragments(tRFs),each with specific subcellular localizations.Additionally,the biogenesis of tsRNAs is tissue-specific and can be regulated by tRNA modifications.In this review,we first elaborated on the classification and biogenesis of tsRNAs.After summarizing the latest mechanisms of tsRNAs,including transcriptional gene silencing,post-transcriptional gene silencing,nascent RNA silencing,translation regulation,rRNA regulation,and reverse transcription regulation,we explored the representative biological functions of tsRNAs in tumors.Furthermore,this review summarized the clinical value of tsRNAs in cancers,thus providing theoretical support for their potential as novel biomarkers and therapeutic targets. | Yu Zhang Xinliang Gu Yang Li Yuejiao Huang Shaoqing Ju | 2024 | Genes & Diseases2024，11，2： | 0 |
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