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| 1 | Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study显示文摘In this historical cohort study,236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors,etanercept or infliximab(n = 80),or by conventional methods(n = 156).Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment(mean 16 months).The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8%(7/80),which was significantly higher than the conventional treatment group(2.6%;4/156).The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41(95% confidence interval:1.03-11.31).Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy.Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy. | Naizhi Wang Yingying Guo Lili Yang Wenyi Fu Yanbing Xu Linxin Hou Shuai Zhao Ning Zhang | 2012 | Neural Regeneration Research2012，7，11： | 2 |
| 2 | Agency Theory and Executive Compensation:The Case of China SOE显示文摘 | Mengistae Taye Linxin Colin Xu | | 0，，： | 1 |
| 3 | Microstructure and properties of Nd:YAG laser welded AZ31B magnesium alloy显示文摘 | Cui Zeqin Cheng Linxin Si En Wang Wenxian Xu Bingshe | 2014 | China Welding2014，23，2： | 1 |
| 4 | Finance and income inequality: what do we the data tell us显示文摘 | CLARKE GREORGE R G LINXIN XU HENG-- FU ZOU | 2006 | Southern Economic Journal2006，72，3： | 1 |
| 5 | Synthesis of poly(pyridine-imide)s and their electronic memory performances显示文摘In this paper,poly(pyridine-imide)s,PI-Ph and PI-Naphth,were successfully synthesised and fabricated for use as memory devices.The Al/PI-Ph/indium tin oxide(ITO)device showed dynamic random access memory characteristics,whereas Al/PI-Naphth/ITO showed rewritable(FLASH)memory characteristics.Characterisation of their UV,cyclic voltammograms,and density functional theory,were used to illustrate the different memory behaviours.The results show that the stability of electric-field-induced-charge-transfer complexes can affect memory performance. | Haifeng Chen Linxin Wu Xiong Xiao Hongliang Wang Jun Jiang Lihua Wang Qingfeng Xu Jianmei Lu | 2017 | Science China Chemistry2017，60，2： | 1 |
| 6 | A YAP/TAZ-CD54 axis is required for CXCR2-CD44-tumor-specific neutrophils to suppress gastric cancer显示文摘As an important part of tumor microenvironment,neutrophils are poorly understood due to their spatiotemporal heterogeneity in tumorigenesis.Here we defined,at single-cell resolution,CD44-CxCR2-neutrophils as tumor-specific neutrophils(tsNeus)in both mouse and human gastric cancer(GC).We uncovered a Hippo regulon in neutrophils with unique YAP signature genes(e.g.,ICAM1,CD14,EGR1)distinct from those identified in epithelial and/or cancer cells.Importantly,knockout of YAP/TAz in neutrophils impaired their differentiation into CD54+tsNeus and reduced their antitumor activity,leading to accelerated GC progression.Moreover,the relative amounts of CD54+tsNeus were found to be negatively associated with GC progression and positively associated with patient survival.Interestingly,GC patients receiving neoadjuvant chemotherapy had increased numbers of CD54+tsNeus.Furthermore,pharmacologically enhancing YAP activity selectively activated neutrophils to suppress refractory GC,with no significant inflammation-related side effects.Thus,our work characterized tumor-specific neutrophils in GC and revealed an essential role of YAP/TAZ-CD54 axis in tsNeus,opening a new possibility to develop neutrophil-based antitumor therapeutics. | Pingping Nie Weihong Zhang Yan Meng Moubin Lin Fenghua Guo Hui Zhang Zhenzhu Tong Meng Wang Fan Chen Liwei An Yang Tang Yi Han Ruixian Yu Wenjia Wang Yuanzhi Xu Linxin Wei Zhaocai Zhou Shi Jiao | 2023 | Protein & Cell2023，14，7： | 0 |
| 7 | Huge pyogenic liver abscess(PLA)in an elderly patient with dia-betes following the pancreaticoduodenectomy显示文摘We described an elderly female with type 2 diabetes referred to our hospital with fever, nausea and upper abdominal pain. The patient had got duodenal tumor and received the pancreaticoduodenectomy(PD)12 years ago. The laboratory examinations revealed white blood cells(WBC)increasing and severe hypocalcemia. Abdominal computed tomography(CT)revealed a huge gas-forming pyogenic liver abscess(PLA)in left lobe of the liver. The patient got cured after correction of calcium metabolism disorders, treatment with antibiotic and receiving percutaneous tube drainage. We concluded that we should remain on high alert of those patients with DM and the history of cancer, when he or she gets fever of unknown origin and abdominal tenderness. PLA should be considered. | Liu Yunfeng Li Linhui Zhang Yi Xu Linxin Yin Jianhong Sun Li Yang Jing | 2019 | 中华内分泌外科杂志2019，13，3： | 0 |
| 8 | A Scheme for Reconstructing Free-form Surface from Shading with Cellular Automata显示文摘The reconstruction of free-form surface is a fundamental problem in digital manufacture.This article presents a novel solution to reconstructing free-form surface from an intensity image under the Lambertian reflection model,that is a method called shape from shading (SFS).Our approach is based on the two-dimensional cellular automata (CA),and fully uses the local information of both image and the reconstructed surface.After several iterations,the free-form surface corresponding to the input image is obtained.The encouraging results on both synthetic and real-world images are provided in this paper,and the perfor- mance of our algorithm is analyzed on synthetic images using mean and standard deviation of depth (Z) errors. | XU Bin TANG Linxin SHI Hanmin (School of Mechanical Science and Engineering,Huazhong University of Science and Technology,Wuhan 430074 China | 2006 | 武汉理工大学学报2006，28，S2： | 0 |
| 9 | Study on the Deformation Characteristics of the Sheet Hydroforming with a Movable Die显示文摘An improved sheet hydroforming process with a movable die is proposed and investigated by elastoplastic FEM. The effects of varied process parameters on the deformation of the sheet blanks were investigated. The effects of the movable die on the FLD were also analyzed. Using a movable die may increase the forming limit of the blank and improve the forming performance. Moreover, the drawing ratio of the blank may be increased by changing the process conditions such as blank holder force and the counterforce of the movable die on the blank. | Linxin ZHOU Yi XU Zhongtang WANG Shihong ZHANG | 2003 | Journal of Materials Science & Technology2003，19，z1： | 0 |
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