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| 1 | Pollution characteristics and health risk assessment of benzene homologues in ambient air in the northeastern urban area of Beijing, China显示文摘Ambient benzene homologues were measured at a site in the northeastern urban area of Beijing, China, from August 24 to September 4, 2012 by SUMMA canister sampling followed by laboratory determination using cryogenic cold trap pre-concentration-GC-MS/FID, and their health risks were also assessed. Daily total benzene homologues ranged from 0.99 to 49.71 μg/m3with an average of 11.98 μg/m3. Benzene homologues showed higher concentrations in the morning and evening than that at noontime. Comparison with previous studies revealed a trend of decrease for ambient benzene homologues probably due to the efective emission control in Beijing in recent years. Vehicular exhaust was the main source while volatilization of paints and solvents also made substantial contributions. Health risk assessment showed that BTEX(benzene, toluene, ethylbenzene, o-xylene, m-xylene and p-xylene) and styrene had no appreciable adverse non-cancer health risks for the exposed population, while benzene has potential cancer risk of 1.34E-05. Available data from cities in China all implied that benzene imposes relatively higher cancer risk on the exposed populations and therefore strict control measures should be taken to further lower ambient benzene levels in China. | Lei Li Hong Li Xinmin Zhang Li Wang Linghong Xu Xuezhong Wang Yanting Yu Yujie Zhang Guan Cao | 2014 | Journal of Environmental Sciences2014，26，1： | 40 |
| 2 | 0.04 degree-per-hour MEMS disk resonator gyroscope with high-quality factor (510 k) and long decaying time constant(74.9 s)显示文摘The disk resonator gyroscope is an attractive candidate for high-performance MEMS gyroscopes.This gyroscope consists of a sensor and readout electronics,and the characteristics of the sensor directly determine the performance.For the sensor,a high-quality factor and long decaying time constant are the most important characteristics required to achieve high performance.We report a disk resonator gyroscope with a measured quality factor of 510 k and decaying time constant of 74.9 s,which is a record for MEMS silicon disk resonator gyroscopes,to the best of our knowledge.To improve the quality factor of the DRG,the quality factor improvement mechanism is first analyzed,and based on this mechanism two stiffness-mass decoupled methods,i.e.,spoke length distribution optimization and lumped mass configuration design,are proposed and demonstrated.A disk resonator gyroscope prototype is fabricated based on these design strategies,and the sensor itself shows an angle random walk as low as 0.001°/√h,demonstrating true potential to achieve navigation-grade performance.The gyroscope with readout electronics shows an angle random walk of 0.01°/√h and a bias instability of 0.04°/h at room temperature without compensation,revealing that the performance of the gyroscope is severely limited by the readout electronics,which should be further improved.We expect that the quality factor improvement methods can be used in the design of other MEMS gyroscopes and that the newly designed DRG can be further improved to achieve navigation-grade performances for high-end industrial,transportation,aerospace,and automotive applications. | Qingsong Li Dingbang Xiao Xin Zhou Yi Xu Ming Zhuo Zhanqiang Hou Kaixuan He Yongmeng Zhang Xuezhong Wu | 2018 | Microsystems & Nanoengineering2018，4，1： | 16 |
| 3 | 深厚软土桥梁桩基荷载传递特性及沉降控制效果研究显示文摘通过杭甬铁路客运专线柯桥特大桥单桩静载试验,桩身应变、桩身压缩量及桥墩沉降的测试,研究深厚软土地区桥梁桩基的荷载传递特性及沉降控制效果。结果表明:桩侧摩阻力先于桩端阻力发挥作用;尽管桩端置于强风化凝灰质砂岩上,但在试验荷载下2根超长试验桩的端承比均小于1.5%,桩的承载特性表现为摩擦桩的性质;单桩静载试验实测的桩身压缩量占桩顶沉降量的85%以上;桥墩浇筑完成后经过753d的沉降观测,2个试验墩实测沉降量分别为3.00和3.41mm,其中,无砟轨道铺设后300d的实测沉降分别为0.11和0.25mm,表明在深厚软土地区采用超长钻孔灌注桩控制桥梁基础沉降的效果显著。 | Xin, Xuezhong Wei, Limin He, Qun | 2012 | 中国铁道科学2012，，4： | 15 |
| 4 | Quantitative description of characteristics of high-capacity channels in unconsolidated sandstone reservoirs using in situ production data显示文摘Quantitative description of the high-capacity channels in unconsolidated sandstone reservoirs,into which water was injected to improve oil recovery,is a hot topic in the fi eld of reservoir development. This paper presents a novel approach to describing quantitatively the characteristics of connected macropores in unconsolidated sandstone reservoirs using in situ production data. Based on physical simulation for formation mechanisms of high capacity channels and interwell tracer test data,a mathematical model was established to describe high-capacity channels by grey correlation theory,glow mechanism of fluid in porous media and reservoir engineering,and a program was developed to describe quantitatively the channel characteristics. The predicted results were consistent with fi eld monitoring data(80%) ,so this model could be economically and effectively used to identify high-capacity channels. | Wang Xuezhong Wang Jianyong Wang Chuanfei Zeng Liufang Liu Xuewei | 2010 | Petroleum Science2010，7，1： | 15 |
| 5 | Neuroprotective effects of Ginkgo biloba extract and GinkgoUde B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model显示文摘 | Xiaohan Yang Tiezheng Zheng Hao Hong Nan Cai Xiaofeng Zhou Changkai Sun Liying Wu Shuhong Liu Yongqi Zhao Lingling Zhu Ming Fan Xuezhong Zhou Fengxie Jin | 2018 | Frontiers of Medicine2018，12，3： | 12 |
| 6 | Precision Balance Method for Cupped Wave Gyro Based on Cup-bottom Trimming显示文摘The mechanical balance process is the key process to eliminate the quadrature error and improve the performance of the cupped wave gyro.The conventional mechanical balance method for cupped wave gyro based on cup-wall trimming requires high control accuracy of trimming quantity,which increases the production cost and decreases the fabrication efficiency in large extent.However,it is hard to reach the high balance accuracy with the natural frequency split of mHz grade by using the conventional method.In this paper,the lumped mass dynamic model of the cupped wave gyro is built by discretization method,and the effects of different position trimming on the natural frequency are analyzed.It is pointed out that trimming off a tiny quantity of material from cup-wall causes large variation of the natural frequency is the main reason for the low accuracy of the conventional mechanical balance method.Then,a precision balance method for cupped wave gyro based on cup-bottom trimming is presented and the entire procedures of this method are given.The static balance process and dynamic balance process of the precision balance method are simulated by the finite element software.The simulation result shows that the precision balance method based on cup-bottom trimming brings less additional natural frequency split in the static balance process,minimizes the natural frequency split to mHz grade and rectify the angle of mode offset to 0.1° grade in the dynamic balance process,furthermore,the method decreases the requirement for control accuracy of trimming quantity evidently.The research work provides references for structure optimization design and balance process plan of the cupped wave gyro. | TAO Yi XI Xiang XIAO Dingbang TAN Yingqi CUI Hongjuan WU Xuezhong | 2012 | Chinese Journal of Mechanical Engineering2012，25，1： | 9 |
| 7 | Nucleocytoplasmic Trafficking of the Arabidopsis WD40 Repeat Protein XIW1 Regulates ABI5 Stability and Abscisic Acid Responses显示文摘WD40 repeat-containing proteins(WD40 proteins)serve as versatile scaffolds for protein-protein interac-tions,modulating a variety of cellular processes such as plant stress and hormone responses.Here we report the identification of a WD40 protein,XIW1(for XPO1-interacting WD40 protein 1),which positively regulates the abscisic acid(ABA)response in Arabidopsis.XIW1 is located in the cytoplasm and nucleus.We found that it interacts with the nuclear transport receptor XPO1 and is exported by XPO1 from the nucleus.Mutation of XIW1 reduces the induction of ABA-responsive genes and the accumulation of ABA Insensitive 5(ABI5),causing mutant plants with ABA-insensitive phenotypes during seed germination and seedling growth,and decreased drought stress resistance.ABA treatment upregulates the expression of XIW1,and both ABA and abiotic stresses promote XIW1 accumulation in the nucleus,where it interacts with ABI5.Loss of XIW1 function results in rapid proteasomal degradation of ABI5.Taken together,these findings suggest that XIW1 is a nucleocytoplasmic shuttling protein and plays a positive role in ABA responses by interacting with and maintaining the stability of ABI5 in the nucleus. | Xuezhong XU Wang Wan Guobin Jiang Yue Xi Haijian Huang Jiajia Cai Yanan Chang Cheng-Guo Duan Satendra KMangrauthia Xinxiang Peng Jian-Kang Zhu Guohui Zhu | 2019 | Molecular Plant2019，12，12： | 8 |
| 8 | The enrichment characteristics of mercury in the sediments of Dongjiu and Xijiu, Taihu Lake catchment, in the past century显示文摘The concentration and the enrichment factors of mercury (Hg) in the sediment cores of Dongjiu and Xijiu, Taihu Lake catchment, were studied. The accumulation fluxes, anthropogenic input concentration and anthropogenic accumulation fluxes of Hg in recent 100 years were also analyzed based on the 210Pb dating. The results indicate that the increasing concentrations of Hg in the sediments are influ-enced by natural factors and anthropogenic input simultaneously. Generally, about 2/3 of the Hg in the sediment was from anthropogenic sources. In the early 20th century, the anthropogenic input was owing to the urban development and fossil fuel consumptions surrounding the Taihu Lake and the worldwide atmospheric deposition of Hg since the industrial revolution. The concentration and an-thropogenic fluxes of Hg increased with the industrial development in the catchment since the 1930s. It reached the maximum during the middle 1970s and middle 1990s, and decreased since the middle 1990s with constraints on high pollution industries. | WU YanHong JIANG XueZhong LIU EnFeng YAO ShuChun ZHU YuXin SUN ZhaoBin | 2008 | Science China Earth Sciences2008，51，6： | 8 |
| 9 | Clinical phenotype network: the underlying mechanism for perso- nalized diagnosis and treatment of traditional Chinese medicine显示文摘繁体中文药(TCM ) 在个性化的药的一个典型纲要调查临床的诊断和治疗整齐,它意味着有一样的疾病的个性化的病人将从不同 TCM 医生获得不同诊断和最佳的治疗。这个原则被 TCM 临床的专业人员认出并且粘住几千年了。然而,个性化的药不是的 TCM 的内在的机制到目前为止充分调查了并且仍然保持未知。这份报纸讨论 TCM 的框架在经典文学并且在真实世界的临床的背景的个性化的药,并且调查 TCM 的内在的机制从网络药的观点的个性化的药。在失眠上基于 246 个设计得好的门诊病人记录,由评估表明观察的个人偏爱和植物药方的偏爱,我们注意了每张植物药方的重要类似和每相遇的症状类似。为了调查 TCM 的内在的机制,个性化药,我们构造了一个临床的显型网络(CPN ) ,在哪个临床的显型实体喜欢症状并且诊断作为连接表现为在这些实体之间的节点和关联。这 CPN 被用来调查症候群和症状的同现的混杂的边界。小世界的拓扑的特征与高聚类结构在 CPN 被注意,它在 TCM 的合理性上提供卓见个性化的诊断和处理。这个网络上的调查将帮助我们在 TCM 的内在的机制上获得理解个性化的药并且将为 TCM 的精炼建议一个新观点个性化的临床的技巧。 | Xuezhong Zhou Yubing Li Yonghong Peng Jingqing HU Runshun Zhang Liyun He Yinghui Wang Lijie Jiang Shiyan Yan Peng Li Qi Xie Baoyan Liu | 2014 | Frontiers of Medicine2014，8，3： | 7 |
| 10 | Three-dimensional dynamic culture of pre-osteoblasts seeded in HA-CS/Col/nHAP composite scaffolds and treated with α-ZAL显示文摘造骨细胞前 MC3T3-E1 房间在玻尿的修改酸的 chitosan/collagen/nano-hydroxyapatite (HA-CS/Col/nHAP ) 是有教养的合成脚手架并且与 phytoestrogen 对待 -zearalanol (为骨头织物工程改进骨头织物形成的 -ZAL) 。灌注和动态紧张被用于三维(3D ) 有教养的房间,它在骨头组织模仿机械微型环境并且解决集体转移问题。在 vitro 的房间支架构造的形态学然后被检验,成骨的标记被 immunohistochemistry 染色并且西方的弄污估计。结果证明房间以一种不规则的方式扩展了他们的 pseudopodia 并且在 3D-dynamic 文化沿着墙分散了。Osteogenic 显型被增加或由提高的骨胶原坚持说(COLI ) 我铺平,减少的 osteopontin 表示和有的很少在 12 天期间在 osteocalcin 上完成表示在 vitro 文化。响应 -ZAL, ,房间支架构造显示出禁止的细胞的增长,提高了碱的磷酸酶(高山) 活动和到原子因素 kappa B (NF-B ) ligand (RANKL ) 的受体使活跃之物的 osteoprotegerin 的增加的比率。到与 -ZAL 对待的房间支架构造的灌注和动态紧张的申请在骨头织物工程的成骨刺激的研究代表一条有希望的途径。 | Lu Liu Yong Guo Xuezhong Chen Ruixin Li Zhihong Li Liang Wang Zongming Wan Jianyu Li Qingxin Hao Hao Li Xizheng Zhang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，8： | 7 |
| 11 | Clinical features and the traditional Chinese medicine therapeutic characteristics of 293 COVID-19 inpatient cases显示文摘Coronavirus disease 2019 (COVID-19) is now pandemic worldwide and has heavily overloaded hospitals in Wuhan City, China during the time between late January and February. We reported the clinical features and therapeutic characteristics of moderate COVID-19 cases in Wuhan that were treated via the integration of traditional Chinese medicine (TCM) and Western medicine. We collected electronic medical record (EMR) data, which included the full clinical profiles of patients, from a designated TCM hospital in Wuhan. The structured data of symptoms and drugs from admission notes were obtained through an information extraction process. Other key clinical entities were also confirmed and normalized to obtain information on the diagnosis, clinical treatments, laboratory tests, and outcomes of the patients. A total of 293 COVID-19 inpatient cases, including 207 moderate and 86 (29.3%) severe cases, were included in our research. Among these cases, 238 were discharged, 31 were transferred, and 24 (all severe cases) died in the hospital. Our COVID-19 cases involved elderly patients with advanced ages (57 years on average) and high comorbidity rates (61%). Our results reconfirmed several well-recognized risk factors, such as age, gender (male), and comorbidities, as well as provided novel laboratory indications (e.g., cholesterol) and TCM-specific phenotype markers (e.g., dull tongue) that were relevant to COVID-19 infections and prognosis. In addition to antiviral/antibiotics and standard supportive therapies, TCM herbal prescriptions incorporating 290 distinct herbs were used in 273 (93%) cases. The cases that received TCM treatment had lower death rates than those that did not receive TCM treatment (17/273= 6.2% vs. 7/20= 35%, P = 0.0004 for all cases;17/77= 22% vs. 7/9= 77.7%, P = 0.002 for severe cases). The TCM herbal prescriptions used for the treatment of COVID-19 infections mainly consisted of Pericarpium Citri Reticulatae, Radix Scutellariae, Rhizoma Pinellia, and their combinations, which reflected the practical TCM principles (e.g., clearing heat and dampening phlegm). Lastly, 59% of the patients received treatment, including antiviral, antibiotics, and Chinese patent medicine, before admission. This situation might have some effects on symptoms, such as fever and dry cough. By using EMR data, we described the clinical features and therapeutic characteristics of 293 COVID-19 cases treated via the integration of TCM herbal prescriptions and Western medicine. Clinical manifestations and treatments before admission and in the hospital were investigated. Our results preliminarily showed the potential effectiveness of TCM herbal prescriptions and their regularities in COVID-19 treatment. | Zixin Shu Yana Zhou Kai Chang Jifen Liu Xiaojun Min Qing Zhang Jing Sun Yajuan Xiong Qunsheng Zou Qiguang Zheng Jinghui Ji Josiah Poon Baoyan Liu Xuezhong Zhou Xiaodong Li | 2020 | Frontiers of Medicine2020，14，6： | 7 |
| 12 | Discussion of solutions to ethical issues in real-world study显示文摘在最近的年里,真实世界的学习(RWS ) 的范例在世界范围的临床的研究的最前线,特别地在繁体中文药的领域里。在这篇论文,真实世界的临床的研究的基本特征和性质被讨论,并且在 RWS 的不同阶段的道德的问题被提出并且考察。而且,这些问题的一些初步的答案例如在 RWS 的过程期间保护题目并且执行道德的评论,基于最近的惯例和基本道德的规则被介绍改进科学有效性和 RWS 的道德的水平。 | Sicheng Wang Baoyan Liu Ningning Xiong Qi Xie Runshun Zhang Xuezhong Zhou Jie Qiao | 2014 | Frontiers of Medicine2014，8，3： | 6 |
| 13 | Chinese multidisciplinary guideline for management of hypertensiveintracerebral hemorrhage显示文摘ypertensive intracerebral hemorrhage(HICH)refers tothe sudden onset of hemorrhage within cerebral paren-chyma or ventricles of patients with a history ofhypertension.Secondary intracerebral hemorrhage(ICH)with an underlying causative pathology,such astrauma,structural blood vessel abnormalities,coagulationor hematological disorder(s),systemic diseases,or neo-plasms,should be excluded to make the diagnosis ofHICH.HICH is characterized by high incidence,disabili-ty,mortality,and recurrence rates.In 2015,experts fromthe Chinese Medical Association branch of Neurosurgery,Chinese Medical Doctor Association branch of theEmergency Physician and Stroke Screening,and Preven-tion and Treatment Committee of the National HealthCommission of the People’s Republic of China gathered toformulate and draft the Chinese Multidisciplinary ExpertsConsensus on the Management of Spontaneous Intrace-rebral Hemorrhage.[1]This consensus has played animportant role in guiding and standardizing the manage-ment of spontaneous ICH in China. | Zhiyuan Yu Chuanyuan Tao Anqi Xiao Cong Wu Min Fu Wei Dong Ming Liu Xuezhong Yu Chao You | 2022 | Chinese Medical Journal2022，135，19： | 6 |
| 14 | Clinical data quality problems and countermeasure for real world study显示文摘真实世界学习(RWS ) 为临床的研究成为了一个热点。数据质量在研究成就和另外的临床的研究领域起一个重要作用。在这篇论文,在繁体中文药的 RWS 的普通优秀问题被讨论,并且一项反措施被建议。 | Runshun Zhang Yinghui Wang Baoyan Liu Guangli Song Xuezhong Zhou Shizhen Fan Xishui Pan | 2014 | Frontiers of Medicine2014，8，3： | 6 |
| 15 | H-tensors and nonsingular H-tensors显示文摘 | Xuezhong WANG Yimin WEI | 2016 | Frontiers of Mathematics in China2016，11，3： | 5 |
| 16 | Clopidogrel improves aspirin response after off-pump coronary artery bypass surgery显示文摘We sought to assess the incidence of aspirin resistance after off-pump coronary artery bypass(OPCAB) surgery,and investigate whether clopidogrel can improve aspirin response and be safely applied early after OPCAB surgery.Sixty patients who underwent standard OPCAB surgery were randomized into two groups.One group(30 patients)received mono-antiplatelet treatment(MAPT) with aspirin 100 mg daily and the other group received dual antiplatelet treatment(DAPT) with aspirin 100 mg daily plus clopidogrel 75 mg daily.Platelet aggregations in response to arachidonic acid(PL_(AA)) and adenosine diphosphate(ADP)(PL_(ADP)) were measured preoperatively and on days 1 to 6,8 and10 after the antiplatelet agents were administered.A PL_(AA) level above 20%was defined as aspirin resistance.Postoperative bleeding and other perioperative variables were also recorded.There were no significant differences between the two groups in baseline characteristics,average number of distal anastomosis,operation time,postoperative bleeding,ventilation time and postoperative hospital stay.However,the incidence of aspirin resistance was significantly lower in the DAPT group than that in the MAPT group on the first and second day after antiplatelet agents were given(62.1%vs.32.1%,34.5%vs.10.7%,respectively,both P < 0.05).There was no significant difference in postoperative complication between the two groups.DAPT with aspirin and clopidogrel can be safely applied to OPCAB patients early after the procedure.Moreover,clopidogrel reduces the incidence of OPCAB-related aspirin resistance. | Xuezhong Wang Xiaoxuan Gong Tiantian Zhu Qiu Zhang Yangyang Zhang Xiaowei Wang Zhijian Yang Chunjian Lia | 2014 | The Journal of Biomedical Research2014，28，2： | 5 |
| 17 | Multistage analysis method for detection of effective herb prescription from clinical data显示文摘为特定的疾病条件或特别的耐心的组决定有效繁体中文药(TCM ) 治疗是因为复杂个性化的表明,在真实世界的病人和在临床的背景规定的个性化的联合治疗要求调查的一个困难的问题。在这研究,集成倾向大小写匹配的一个多级式的分析方法,复杂网络分析,和植物给了丰富分析被建议为特别疾病识别有效植物药方(例如,失眠) 。首先,匹配的倾向大小写被使用匹配临床的盒子。然后,核心网络抽取和植物集合丰富被联合检测核心有效植物药方。基于有效性的相互的信息被用来检测强壮的 herbsymptom 关系。这个方法在一个 TCM 临床的数据集合上被使用, 955 个病人从设计得好的观察研究收集了。结果与更高的有效性率揭示了那组植物药方(76.9% 对 42.8% 为匹配的样品;94.2% 对 84.9% 为所有样品) 与原版相比,药方被发现。有症状表明的特别的耐心的组也被识别帮助调查有效植物药方的指示。 | Kuo Yang Runshun Zhang Liyun He Yubing Li Wenwen Liu Changhe Yu Yanhong Zhang Xinlong Li Yan Liu Weiming Xu Xuezhong Zhou Baoyan Liu | 2018 | Frontiers of Medicine2018，12，2： | 5 |
| 18 | Polyvinylamine-Based Facilitated Transport Membranes for Post-Combustion CO_(2) Capture:Challenges and Perspectives from Materials to Processes显示文摘Carbon dioxide(CO_(2))capture by gas-separation membranes has become increasingly attractive due to its high energy efficiency,relatively low cost,and environmental impact.Polyvinylamine(PVAm)-based facilitated transport(FT)membranes were developed in the last decade for CO_(2) capture.This work discusses the challenges of applying PVAm-based FT membranes from materials to processes for postcombustion CO_(2) capture in power plants and cement factories.Experiences learned from a pilot demonstration system can be used to guide the design of other membranes for CO_(2) capture.The importance of module and process design is emphasized in the achievement of a high-performance membrane system.Moreover,the results from process simulation and cost estimation indicate that a three-stage membrane system is feasible for achieving a high CO_(2) purity of 95 vol%.The specific CO_(2) capture cost was found to significantly depend on the required CO_(2) capture ratio,and a moderate CO_(2) capture ratio of 50%presented a cost of 63.7USD per tonne CO_(2) captured.Thus,FT membrane systems were found to be more competitive for partial CO_(2) capture. | Xuezhong He | 2021 | Engineering2021，7，1： | 4 |
| 19 | Neuroprotective effects of combined lead and cadmium,as well as N-acetylcysteine,on cerebral cortical neurons following lipid peroxidation injury显示文摘BACKGROUND:Studies have reported the antioxidant effects of lead and cadmium in the central nervous system,but very few have addressed the combined toxicity of lead and cadmium.The mechanisms by which these combined heavy metals are toxic,as well as how to protect cells from these agents,remains poorly understood. OBJECTIVE:Primary cultured rat cortical neurons were used to determine the effects of combined lead and cadmium on levels of glutathione peroxidase(GSH-Px),superoxide dismutase(SOD), catalase(CAT),and acetylcholinesterase(AChE),as well as malondialdehyde(MDA),and to evaluate the neuroprotective effects of N-acetylcysteine(NAC). DESIGN,TIME AND SETTING:An in vitro toxicological observation was performed at the Comparative Medicine Center of Yangzhou University from August 2007 to April 2008. MATERIALS:Lead acetate,cadmium acetate,and NAC were purchased from Sigma-Aldrich(St. Louis,USA).Commercial kits of GSH-Px,SOD,CAT,AChE,and MDA were purchased from Nanjing Jiancheng Bioengineering Institute,Nanjing,China. METHODS:The cerebral cortical neurons were isolated from newborn Sprague dawley rats at 24 hours after birth and primary cultured for 6 days.Thereafter,the cells were treated with a range of cadmium doses(0,5.0,and 10.0μmol/L),lead doses(0,1.0,and 2.0μmol/L),or a combination of the two for 12 hours at 37℃in a 5%CO_2 incubator,respectively.In addition,the cells were incubated with different doses of cadmium and/or lead and(0 and 50μmol/L) NAC for 12 hours to assess the protective effects on cell survival. MAIN OUTCOME MEASURES:The activity of SOD,GSH-Px,CAT,and AChE,as well as MDA content,in the cell lysates was detected using commercial kits. RESULTS:At 12 hours after treatment,compared to the control group,activity of GSH-Px,SOD, and AChE in the lead,cadmium,or combined treated cells was significantly decreased with increasing doses of cadmium/or lead(P<0.05),but CAT activity and MDA levels were significantly increased(P<0.05).The combination of cadmium and lead led to higher levels of toxicity than individual exposure. CONCLUSION:The degree of oxidative damage increased when the two heavy metals were combined.NAC protected neonatal cortical neurons by increasing activity of anti-oxidative enzymes, and reducing lipid peroxidation,but the reduction was not statistically significant. | Yumei Zhang Hao Lu Yan Yuan Xuezhong Liu Zongping Liu | 2009 | Neural Regeneration Research2009，4，11： | 4 |
| 20 | High-efficiency simultaneous extraction of rare earth elements and iron from NdFeB waste by oxalic acid leaching显示文摘Iron can not be recovered at high value because only rare earth elements are effectively recovered from NdFeB waste via oxidation roasting-hydrochloric acid leaching process.In this study,a new method for leaching NdFeB waste with oxalic acid was developed.The high-efficiency,simultaneous and high-value recovery of rare earth elements and iron was realized to simplify the process and improve the economic benefit.Results of the oxalic acid leaching experiments show that under the optimum leaching conditions at 90℃ for 6 h in the aqueous solution of oxalic acid(2 mol/L) with a liquid-solid ratio of60 mL/g,the iron leaching efficiency and precipitation rate of rare earth oxalate reach 93.89% and 93.17%,respectively.Rare earth oxalate and Fe(C_(2)O_(4))3^(3-) were left in the residue and the leaching solution,respectively.The leaching mechanism was further analyzed by characterising the leach residues obtained through X-ray powder diffraction(XRD) and scanning electron microscopy-energy dispersive X-ray spectroscopy(SEM-EDS).Results of the leaching kinetics study indicate that the process of oxalic acid leaching follows the shrinking nucleus model,and the leaching kinetics model is controlled by the mixed factors of diffusion and chemical reaction.The leaching residue was calcined at 850℃ for 3 h and then decomposed into rare earth oxide,which can be directly used to prepare rare earth alloy via molten salt electrolysis.For the leaching solution,ferric oxalate solution was reduced using Fe powder to prepare the ferrous oxalate(FeC_(2)O_(4)-2H_(2)O). | Qingsheng Liu Tao Tu Hao Guo Huajin Cheng Xuezhong Wang | 2021 | Journal of Rare Earths2021，39，3： | 4 |
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