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| 1 | First dark matter search results from the PandaX-Ⅰ experiment显示文摘We report on the first dark-matter(DM)search results from PandaX-I,a low threshold dual-phase xenon experiment operating at the China JinPing Underground Laboratory.In the 37-kg liquid xenon target with 17.4 live-days of exposure,no DM particle candidate event was found.This result sets a stringent limit for low-mass DM particles and disfavors the interpretation of previously-reported positive experimental results.The minimum upper limit,3.7×10-44cm2,for the spin-independent isoscalar DM-particle-nucleon scattering cross section is obtained at a DM-particle mass of 49 GeV/c2at 90%confidence level. | XIAO MengJiao XIAO Xiang ZHAO Li CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HU Jie HUANG XingTao JI XiangDong JU YongLin LEI SiAo LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing STEPHENSON Scott TAN AnDi TARL Greg WANG HongWei WANG JiMin WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIE PengWei YOU YingHui ZENG XiongHui ZHANG Hua ZHANG Tao ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，11： | 10 |
| 2 | PandaX: a liquid xenon dark matter experiment at CJPL显示文摘PandaX is a large liquid-xenon detector experiment usable for direct dark-matter detection and 136Xe double-beta decay search.The central vessel was designed to accommodate a staged target volume increase from initially 120 kg(stage I)to 0.5 t(stage II)and eventually to a multi-ton scale.The experiment is located in the Jinping Deep-Underground Laboratory in Sichuan,China.The detector operates in dual-phase mode,allowing detection of both prompt scintillation,and ionization charge through proportional scintillation.In this paper a detailed description of the stage I detector design and performance as well as results established during the commissioning phase are presented. | CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HE Ming HU Jie HUANG XingTao JI XiangDong JU YongLin LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing SHI YuJie STEPHENSON Scott TAN AnDi TARLé Greg WANG HongWei WANG JiMing WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIAO MengJiao XIAO Xiang XIE PengWei YE Tao YOU YingHui ZEN XiongHui ZHANG Hua ZHANG Tao ZHAO HaiYing ZHAO Li ZHOU XiaoPeng ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 9 |
| 3 | Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2. | HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 6 |
| 4 | Are bone marrow regenerative cells ideal seed cells for the treatment of cerebral ischemia?显示文摘Bone marrow cells for the treatment of ischemic brain injury may depend on the secretion of a large number of neurotrophic factors. Bone marrow regenerative cells are capable of increasing the secretion of neurotrophic factors. In this study, after tail vein injection of 5-fluorouracil for 7 days, bone marrow cells and bone marrow regenerative cells were isolated from the tibias and femurs of rats, and then administered intravenously via the tail vein after focal cerebral ischemia. Immunohistological staining and reverse transcription-PCR detection showed that transplanted bone marrow cells and bone marrow regenerative cells could migrate and survive in the ischemic regions, such as the cortical and striatal infarction zone. These cells promote vascular endothelial cell growth factor mRNA expression in the ischemic marginal zone surrounding the ischemic penumbra of the cortical and striatal infarction zone, and have great advantages in promoting the recovery of neurological function, reducing infarct size and promoting angiogenesis. Bone marrow regenerative cells exhibited stronger neuroprotective effects than bone marrow cells. Our experimental findings indicate that bone marrow regenerative cells are preferable over bone marrow cells for cell therapy for neural regeneration after cerebral ischemia. Their neuroprotective effect is largely due to their ability to induce the secretion of factors that promote vascular regeneration, such as vascular endothelial growth factor. | Yi Li Xuming Hua Fang Hua Wenwei Mao Liang Wan Shiting Li | 2013 | Neural Regeneration Research2013，8，13： | 5 |
| 5 | Apoptotic and nonapoptotic function of caspase 7 in spermatogenesis显示文摘最近的研究报导了 7 有的那 caspase apoptotic 和 nonapoptotic 功能。然而,在 caspase 之间的关系 7 并且精子发生仍然保持未知。这研究试图调查 caspase 的可能的功能 7 在正常、反常的精子发生期间。caspase 的劈开的形式 7 被 qRT-PCR,西方的污点和 immunohistochemistry (IHC ) 在不同产后的时间(5-14 星期) 在睾丸纸巾检测。然后, spermatogenic 机能障碍的老鼠模型被 busulfan 获得(进一步评估 caspase 的潜在的功能和机制的 30 mg kg −1 7。qRT-PCR 和西方的污点结果显示出那 caspase 7 表示逐渐地从 5 ~ 14 个星期被提高,它没与 apoptosis 被连接。IHC 结果表明 7 主要是的 caspase 在 spermatogenic 定位了房间和 Leydig 房间。另外, busulfan 逐渐地导致的 spermatogenic 机能障碍提高了 apoptosis 并且提高了 caspase 的表示 3, caspase 6,并且 caspase 9,但是减少 caspase 的表示 7 在 spermatogenic 房间。然而, spermatogenic 房间是什么时候,主要在 busulfan 处理以后在第四个星期消失了, caspase 在 Leydig 房间的 7 表示显著地被增加并且断然与 caspase 的表示相关 3, caspase 6,并且 caspase 9。因此,这些结果显示 7 有的那 caspase 参予正常精子发生的一个 nonapoptic 函数,而且在 spermatogenic 的显示器 apoptotic 功能机能障碍。 | Bin Lei Xuming Zhou Daojun Lv Bo Wan Huayan Wu Liren Zhong Fangpeng Shu Xiangming Mao | 2017 | Asian Journal of Andrology2017，19，1： | 2 |
| 6 | The Adiponectin Signaling Pathway as a Novel Pharmocological Target显示文摘 | Xuming Mao | 2006 | MiniReviews in Medicinalhemistry2006，6，： | 1 |
| 7 | Merkel cell carcinoma of the earlobe in a diabetes mellitus patient显示文摘 | Li Yun Qu Tao Sun Qiuning Mao Xuming Fang Kai | 2014 | Chinese Medical Journal2014，，8： | 0 |
| 8 | Functional analysis of ScSwil and CaSwil in invasive and pseudohyphal growth of Saccharomyces cerevisiae显示文摘这里,我们报导了那,在 Saccharomyces cerevisiae,删除 Swi1 (ScSwi1 ) ,在 Swi/Snf 建筑群,侵略生长的引起的缺点, pseudohyphal 生长, FLO11 表示,和合适的房间分离的一个核心部件。进 swi1 异种的 SWI1 的再介绍能压制观察的所有缺点。我们也证明那生产过多的 Swi1 能在 haploids 在 diploids,然而并非侵略生长在 pseudohyphal 生长压制 flo8 细胞的缺点。SWI1 的 Overexpression 不能在侵略生长或 pseudohyphal 生长绕过 Ste12 或 Tec1 的要求。我们断定 Swi/Snf 建筑群为 FLO11 表示和合适的房间分离被要求,并且 FLO8 和 STE12 基因应该是在场的让建筑群为侵略生长工作,但是仅仅 STE12 基因为 pseudohyphal 生长被要求。Candida albicans SWI1 (CaSWI1 ) 的宫外的表示能部分补充 haploid Scswi1 异种检验的缺点,但是没能补充双 Scswi1/Scswi1 异种检验的缺点。侵略的减轻的 Overexpressing CaSwi1 和 pseudohyphal 生长背叛从删除导致 MAP kinase 和营地小径。S 的正直。cerevisiae Swi/Snf 建筑群为 overexpressing CaSwi1 支持的侵略、细丝状的生长被要求。 | Xuming Mao Xinyi Nie Fang Cao Jiangye Chen | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 0 |
| 9 | Comparative Genomics Reveals Evolutionary Drivers of Sessile Life and Left-right Shell Asymmetry in Bivalves显示文摘Bivalves are species-rich mollusks with prominent protective roles in coastal ecosystems.Across these ancient lineages,colony-founding larvae anchor themselves either by byssus production or by cemented attachment.The latter mode of sessile life is strongly molded by left-right shell asymmetry during larval development of Ostreoida oysters such as Crassostrea hongkongensis.Here,we sequenced the genome of C.hongkongensis in high resolution and compared it to reference bivalve genomes to unveil genomic determinants driving cemented attachment and shell asymmetry.Importantly,loss of the homeobox gene Antennapedia(Antp)and broad expansion of lineagespecific extracellular gene families are implicated in a shift from byssal to cemented attachment in bivalves.Comparative transcriptomic analysis shows a conspicuous divergence between leftright asymmetrical C.hongkongensis and symmetrical Pinctada fucata in their expression profiles.Especially,a couple of orthologous transcription factor genes and lineage-specific shell-related gene families including that encoding tyrosinases are elevated,and may cooperatively govern asymmetrical shell formation in Ostreoida oysters. | Yang Zhang Fan Mao Shu Xiao Haiyan Yu Zhiming Xiang Fei Xu Jun Li Lili Wang Yuanyan Xiong Mengqiu Chen Yongbo Bao Yuewen Deng Quan Huo Lvping Zhang Wenguang Liu Xuming Li Haitao Ma Yuehuan Zhang Xiyu Mu Min Liu Hongkun Zheng Nai-Kei Wong Ziniu Yu | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 0 |
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