|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Combined treatment of vitamin K_2 and angiotensin-converting enzyme inhibitor ameliorates hepatic dysplastic nodule in a patient with liver cirrhosis显示文摘Although it is well known that the hepatocellular carcinoma (HCC) is an ominous complication in patients with liver cirrhosis, there has been no approved drug to prevent the development of HCC to date. We previously reported that the combined treatment of vitamin K2 (VK) and angiotensin-converting enzyme inhibitor (ACE-I) significantly suppressed the experimental hepatocarcinogenesis. A 66-year-old Japanese woman with hepatitis C virus (HCV)-related liver cirrhosis developed a dysplastic nodule in the liver detected by enhanced computed tomography along with elevation of the tumor markers, namely, alpha-fetoprotein (AFP) and lectin-reactive demarcation (AFP-L3), suggesting the presence of latent HCC. After oral administration of VK and ACE-I, the serum levels of both AFP and AFP-L3 gradually decreased without any marked alteration of the serum aminotransferase activity. After one-year treatment, not only the serum levels of AFP and AFP-L3 returned to the normal ranges, but also the dysplastic nodule disappeared. Since both VK and ACE-I are widely used without serious side effects, this combined regimen may become a new strategy for chemoprevention against HCC. | Hitoshi Yoshiji Ryuichi Noguchi Masaharu Yamazaki Yasuhide Ikenaka Masayoshi Sawai Masatoshi Ishikawa Hideto Kawaratani Tsuyoshi Mashitani Mitsuteru Kitade Kosuke Kaji Masahito Uemura Junichi Yamao Masao Fujimoto Akira Mitoro Masahisa Toyohara Motoyuki Yoshida Hiroshi Fukui | 2007 | World Journal of Gastroenterology2007，13，23： | 5 |
| 2 | Eosinophilic cholecystitis along with pericarditis caused by Ascaris lumbricoides: A case report显示文摘Although the etiology of eosinophilic cholecystitis is still obscure, the postulated causes include allergies, parasites, hypereosinophilic syndrome, and eosinophilic gastroenteritis. It is sometimes accompanied by several complications, but a simultaneous onset with pericarditis is very rares. A 28-year-old woman complained of acute right hypocondrial pain and dyspnea associated with systemic eruption. Several imaging modalities revealed acute cholecystitis and pericarditis with massive pericardial effusion. A marked peripheral blood eosinophilia was observed, and the eruption was diagnosed as urticaria. Her serum had a high titer of antibody against Ascaris lumbricoides . Treatment with albendazole drastically improved all clinical manifestations along with normalization of the imaging features and eosinophilia. We report herein a rare case of simultaneous onset of acute cholecystitis and pericarditis associated with a marked eosinophilia caused by parasitic infection. | Kosuke Kaji Hitoshi Yoshiji Masahide Yoshikawa Masaharu Yamazaki Yasuhide Ikenaka Ryuichi Noguchi Masayoshi Sawai Masatoshi Ishikawa Tsuyoshi Mashitani Mitsuteru Kitade Hideto Kawaratani Masahito Uemura Junichi Yamao Masao Fujimoto Akira Mitoro Masahisa Toyohara Motoyuki Yoshida Hiroshi Fukui | 2007 | World Journal of Gastroenterology2007，13，27： | 3 |
| 3 | Simulation of soil deformation and resistance at bar penetration by the Distinct Element Method显示文摘 | Hiroaki Tanaka Masatoshi Momozu Akira Oida Minoru Yamazaki | 2000 | Journal of Terramechanics2000，，1： | 2 |
| 4 | Restrictive versus liberal blood transfusion policy for hepatectomies in cirrhotic patients显示文摘 | Masatoshi Makuuchi M.D. Tadatoshi Takayama M.D. Peter Gunvén M.D. Tomoo Kosuge M.D. Susumu Yamazaki M.D. Hiroshi Hasegawa M.D | 1989 | World Journal of Surgery1989，，5： | 1 |
| 5 | Changes in serum cholesterol levels determine future risk of cardiovascular events in patients with acute coronary syndrome in the Japanese Coronary Artery Disease (JCAD) Study显示文摘 | Shota Fukuda Kenei Shimada Masatoshi Fujita Minoru Yoshiyama Junichi Yoshikawa Takahide Kohro Doubun Hayashi Tsutomu Yamazaki Ryozo Nagai | 2013 | Journal of Cardiology2013，，6： | 1 |
| 6 | Nanoparticles in Emissions and Atmospheric Environment: Now and Future显示文摘 | Seishiro Hirano Hiroshi Nitta Yuichi Moriguchi Shinji Kobayashi Yoshinori Kondo Kiyoshi Tanabe Takahiro Kobayashi Shinji Wakamatsu Masatoshi Morita Satoshi Yamazaki | 2003 | Journal of Nanoparticle Research (-)2003，，3： | 1 |
| 7 | A case of short - coupled variant of torsade de pointes char-acterized by spatial heterogeneity of action potential duration andits restitution kinetics 显示文摘 | Masatoshi Yamazaki Toshiyuki Osaka Eriko Yokoyama etal | 2006 | J Interv Card Electrophysiol2006，17，1： | 1 |
| 8 | Luteolin as an Anti-inflammatory and Anti-allergic Constituent of Perilla frutescens显示文摘 | Hiroshi UEDA Chikako YAMAZAKI Masatoshi YAMAZAKI | 2002 | Biol Pharm Bull2002，25，9： | 1 |
| 9 | Overexpression of the miR-34 family suppresses invasive growth of malignantmelanoma with the wild-type p53 gene显示文摘 | Hitoshi Yamazaki Tsuyoshi Chijiwa Yoshimasa Inoue Yoshiyuki Abe Hiroshi Suemizu Kenji Kawai Masatoshi Wakui Daisuke Furukawa Masaya Mukai Sadahito Kuwao Makoto Saegusa Masato Nakamura | 2012 | Experimental and Therapeutic Medicine2012，，5： | 1 |
| 10 | Antioxidative function of kiwi fruit and oxidative damage in host显示文摘 | YAMAZAKI MASATOSHI | 2000 | Bio Ind2000，17，11： | 1 |
| 11 | On the polar decomposition of the Aluthge transformation and related results显示文摘 | Ito Masatoshi Yamazaki Takeaki Yanagida Masahiro | 2004 | Journal Operator Theory2004，51，： | 1 |
| 12 | On the polar decomposition of the product of two operators and its applications显示文摘 | Ito Masatoshi Yamazaki Takeaki Yanagida Masahiro | 2004 | Integral Equation Operator Theory2004，49，： | 1 |
| 13 | Central bisegmentectomy of the liver: Experience in 16 patients显示文摘 | Hiroshi Hasegawa M.D. Masatoshi Makuuchi M.D. Susumu Yamazaki M.D. Peter Gunvén M.D | 1989 | World Journal of Surgery1989，，6： | 1 |
| 14 | Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla fruteseens显示文摘 | HIROSHI UEDA CHIKAKO YAMAZAKI MASATOSHI YAMAZAKI | 2002 | Biol Pharm Bull2002，25，9： | 1 |
| 15 | Extended therapy duration for therapy-refractory hepatitis C patients with genotype 2显示文摘We devised an extended 72-wk peginterferon--2a/ribavirin therapy regimen for the retreatment of highly intractable cases,i.e.,48-wk peginterferon--2b/ribavirin therapy-intractable cases.Although 2 cases achieved a rapid virological response to 72-wk peginterferon--2a/ribavirin therapy,1 case failed to achieve a sustained virological response.Although the reason for this difference in the effectiveness of 72-wk peginterferon--2a/ribavirin therapy between the cases was unclear,the rebound phenomenon of serum transaminase after48-wk peginterferon--2b/ribavirin therapy and the resultant lower viral load compared to that before 48-wk peginterferon--2b/ribavirin therapy might have influenced the treatment outcome.Thus,it may be beneficial to consider the rebound phenomenon of serum transaminase and the changes in viral load resulting from previous interferon-based therapy and then cau-tiously determine the indication and the timing of the administration of 72-wk peginterferon--2a/ribavirin in highly intractable cases.Further studies should be performed to confirm this strategy. | Ken Sato Masatoshi Yanagisawa Hiroaki Hashizume Yuichi Yamazaki Norio Horiguchi Satoru Kakizaki Masatomo Mori | 2013 | World Journal of Gastroenterology2013，19，34： | 0 |
| 16 | Clinical utility of treatment method conversion during single-session endoscopic ultrasound-guided biliary drainage显示文摘BACKGROUND Although several techniques for endoscopic ultrasound-guided biliary drainage(EUS-BD)are available at present,an optimal treatment algorithm of EUS-BD has not yet been established.AIM To evaluate the clinical utility of treatment method conversion during single endoscopic sessions for difficult cases in initially planned EUS-BD.METHODS This was a single-center retrospective analysis using a prospectively accumulated database.Patients with biliary obstruction undergoing EUS-BD between May 2008 and April 2016 were included.The primary outcome was to evaluate the improvement in EUS-BD success rates by converting the treatment methods during a single endoscopic session.Secondary outcomes were clarification of the factors leading to the conversion from the initial EUS-BD and the assessment of efficacy and safety of the conversion as judged by technical success,clinical success,and adverse events(AEs).RESULTS A total of 208 patients underwent EUS-BD during the study period.For 18.8%(39/208)of the patients,the treatment methods were converted to another EUSBD technique from the initial plan.Biliary obstruction was caused by pancreatobiliary malignancies,other malignant lesions,biliary stones,and other benign lesions in 22,11,4,and 2 patients,respectively.The reasons for the difficulty with the initial EUS-BD were classified into the following 3 procedures:Target puncture(n=13),guidewire manipulation(n=18),and puncture tract dilation(n=8).Technical success was achieved in 97.4%(38/39)of the cases and clinical success was achieved in 89.5%of patients(34/38).AEs occurred in 10.3%of patients,including bile leakage(n=2),bleeding(n=1),and cholecystitis(n=1).The puncture target and drainage technique were altered in subsequent EUSBD procedures in 25 and 14 patients,respectively.The final technical success rate with 95%CI for all 208 cases was 97.1%(95%CI:93.8%-98.9%),while that of the initially planned EUS-BD was 78.8%(95%CI:72.6%-84.2%).CONCLUSION Among multi-step procedures in EUS-BD,guidewire manipulation appeared to be the most technically challenging.When initially planned EUS-BD is technically difficult,treatment method conversion in a single endoscopic session may result in successful EUS-BD without leading to severe AEs. | Kosuke Minaga Mamoru Takenaka Kentaro Yamao Ken Kamata Shunsuke Omoto Atsushi Nakai Tomohiro Yamazaki Ayana Okamoto Rei Ishikawa Tomoe Yoshikawa Yasutaka Chiba Tomohiro Watanabe Masatoshi Kudo | 2020 | World Journal of Gastroenterology2020，26，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员