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| 1 | Comprehensive strategy of conduit guidance combined with VEGF producing Schwann cells accelerates peripheral nerve repair显示文摘Peripheral nerve regeneration requires stepwise and well-organized establishment of microenvironment.Since local delivery of VEGF-A in peripheral nerve repair is expected to promote angiogenesis in the microenvironment and Schwann cells(SCs)play critical role in nerve repair,combination of VEGF and Schwann cells may lead to efficient peripheral nerve regeneration.VEGF-A overexpressing Schwann cells were established and loaded into the inner wall of hydroxyethyl cellulose/soy protein isolate/polyaniline sponge(HSPS)conduits.When HSPS is mechanically distorted,it still has high durability of strain strength,thus,can accommodate unexpected strain of nerve tissues in motion.A 10 mm nerve defect rat model was used to test the repair performance of the HSPS-SC(VEGF)conduits,meanwhile the HSPS,HSPS-SC,HSPS-VEGF conduits and autografts were worked as controls.The immunofluorescent co-staining of GFP/VEGF-A,Ki67 and MBP showed that the VEGF-A overexpressing Schwann cells could promote the proliferation,migration and differentiation of Schwann cells as the VEGF-A was secreted from the VEGF-A overexpressing Schwann cells.The nerve repair performance of the multifunctional and flexible conduits was examined though rat behavioristics,electrophysiology,nerve innervation to gastrocnemius muscle(GM),toluidine blue(TB)staining,transmission electron microscopy(TEM)and NF200/S100 double staining in the regenerated nerve.The results displayed that the effects on the repair of peripheral nerves in HSPS-SC(VEGF)group was the best among the conduits groups and closed to autografts.HSPS-SC(VEGF)group exhibited notably increased CD31+endothelial cells and activation of VEGFR2/ERK signaling pathway in the regenerated nerve tissues,which probably contributed to the improved nerve regeneration.Altogether,the comprehensive strategy including VEGF overexpressing Schwann cells-mediated and HSPS conduit-guided peripheral nerve repair provides a new avenue for nerve tissue engineering. | Ping Wu Zan Tong Lihua Luo Yanan Zhao Feixiang Chen Yinping Li Céline Huselstein Qifa Ye Qingsong Ye Yun Chen | 2021 | Bioactive Materials2021，6，10： | 4 |
| 2 | Tall gastrodis tuber combined with antiepileptic drugs repairs abnormal perfusion foci in focal epilepsy显示文摘One hundred patients with focal epilepsy were recruited for the present study and their seizures controlled with antiepileptic drugs. The patients then orally received a capsule of tall gastrodis tuber powder, a traditional Chinese drug, and underwent single photon emission computed tomography, long-term electroencephalogram, and CT/MRI. Blood drug levels were monitored throughout the study. Before treatment with tall gastrodis tuber, 35 of the 100 cases had abnormal CT/MRI scans; 79 cases had abnormal single photon emission computed tomography images; 86 cases had abnormal electroencephalogram; and a total of 146 abnormal perfusion foci were observed across the 100 subjects. After treatment, the number of patients with normal single photon emission computed tomography images increased by 12; normal electroencephalogram was observed in an additional 27 cases and the number of patients with epileptiform discharge decreased by 29 (34% of 86); the total number of abnormal perfusion foci decreased by 52 (36%) and changes in abnormal foci were visible in 65 patients. These changes indicate that the administration of tall gastrodis tuber in combination with antiepileptic drugs repairs abnormal perfusion foci in patients with focal epilepsy. Our results demonstrate that traditional Chinese drugs can repair abnormal perfusion foci and, as such, are a promising new pathway in the treatment of focal epilepsy. | Weimin Wang Zhenyu Fan Yongqin Zhang Yuxia Yang Yaqing Liu Xiaoli Dang Wenjun Song Yinping Wu Jiang Ye | 2013 | Neural Regeneration Research2013，8，3： | 2 |
| 3 | An Investigation of Friction and Wear Performances of Bonded Molybdenum Disulfide Solid Film Lubricants in Fretting Conditions显示文摘 | Ye Yinping Chert Jianmin Zhou Huidi | 2009 | Wear2009，266，78： | 1 |
| 4 | 显示文摘 | Ye Yinping Zhou Huidi Chen Jianmin | 2005 | Nanotechnology and Precision Engineering2005，3，1： | 1 |
| 5 | An investigation of friction and wear performances of bonded molybdenum disulfide solid film lubricants in fretting conditions显示文摘 | YE Yinping CHEN Jianmin ZHOU Huidi | 2009 | Wear2009，266，78： | 1 |
| 6 | One - step process to fabrication of transparent superhydrophobic SiO2 paper 显示文摘 | Li Jian Wan Hongqi Ye Yinping | 2012 | Applied Surface Science2012，261，： | 1 |
| 7 | Bisphenol-A rapidly promotes dynamic changes in hippocampal dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation of NMDA receptor subunit NR2B 显示文摘 | Xu Xiaohong Ye Yinping Li Tao | 2010 | Toxicology and Applied Pharmacology2010，249，2： | 1 |
| 8 | Microstructure and mechanical properties of yttria-stabilized ZrO2/Al2O3 nanocomposite ceramics显示文摘 | Ye Yinping Li Jiangong Zhou Huidi | 2008 | Ceram Int2008，34，8： | 1 |
| 9 | Densification and Grain Growth During Pressureless Sintering of TiO2 Nnoceramics显示文摘 | Li Jiangong Ye Yinping Shen Liya | 2005 | Materials Science and Engineering2005，390，12： | 1 |
| 10 | Corrosion and tribocorrosion resistance of MAO-based composite coating on AZ31 magnesium alloy显示文摘In this paper, a multi-functional composite coating with low friction coefficient, high wear resistance and excellent tribocorrosion resistance is fabricated on AZ31 Mg alloys by micro-arc oxidation and spray-coating methods. The microstructure, and composition of the coating are characterized by SEM, EDS, XRD, and FT-IR. Potentiodynamic polarization and EIS tests are conducted to evaluate the corrosion resistance of the composite coating. The tribocorrosion property is also studied using pin-on-disk tribometer in 3.5 wt.% Na Cl solution. It is found that the composite coating possesses better long-term corrosion resistance than the single MAO coating. The tribocorrosion tests prove that the composite coating exhibits much better wear and tribocorrosion resistance than the single MAO coating and can protect the substrate from corrosion under a sliding condition. | Siqin Liu Guihua Li Yuming Qi Zhenjun Peng Yinping Ye Jun Liang | 2022 | Journal of Magnesium and Alloys2022，10，12： | 0 |
| 11 | Interpretation on Daily Diet and Exercise Management for Diabetes Mellitus显示文摘Diabetes mellitus is an increasing health problem worldwide.With the increased prevalence,the diabetes-related complications,including neuropathy,retinopathy,nephropathy as well as cardiovascular and cerebrovascular diseases,become much more common,and has gradually increased the burden on the individuals and healthcare systems.For the patients with type 2 diabetes mellitus,the prevention and management measures mainly include glucose control and lifestyle interventions.It has been confirmed that lifestyle interventions seem to be at least as effective as pharmacological interventions in people with impaired glucose tolerance.Therefore,interventions to lifestyle are very important for preventing diabetes mellitus.In this article,the prevention measures of diabetes mellitus were analyzed and summarized through lifestyle interventions,mainly in the aspects of daily diet and exercise management. | ye zhenhua oscar du fu-rong wu yinping huang lei | 2016 | 中西医结合护理(中英文)2016，2，12： | 0 |
| 12 | Effect of Ti Incorporation on the Microstructure and Properties of the a-C:H Films Deposited by Magnetron Sputtering Technique显示文摘Amorphous hydrogenated carbon(a-C:H)and Ti-incorporated a-C:H(Ti/a-C:H)films were deposited by magnetron sputtering with a mixture gas of CH4 and Ar.The effect of the Ti incorporation on the chemical composition,microstructure and properties of the as-deposited and the annealed films were investigated by various techniques.It has been shown that the bonding structure and the internal stress were sensitive to the incorporation of the Ti atoms.The results of the XPS revealed that the concentration of Ti atom on the surface of the film increased when the Ti/a-C:H film annealed at 300oC.The tribologcial properties of the(Ti/)a-C:H films changed greatly after annealed,due to the graphitization,oxidation of carbon,and so forth.It compared and discussed in detail the change of the microstructure and properties of the a-C:H and Ti/a-C:H films before and after | Wang Yongxia Ye Yinping Li Hongxuan Ji Li Wang Yongjun Wu Yanxia Liu Xiaohong Chen Jianmin Zhou Huidi | 2012 | 稀有金属材料与工程2012，41，S1： | 0 |
| 13 | Interpretation on Daily Diet and Exercise Management for Hypertension显示文摘Hypertension is a major health problem with great consequences for public health,characterized by persistently-elevated blood pressure.In recent years,more and more studies have shown that unhealthy lifestyles play decisive roles in the development of hypertension,such as psychosocial stress,obesity,excessive intake of salt,smoking,excessive drinking,and lack of physical activity.Therefore,interventions to lifestyles are very important in decrease of blood pressure and cardiovascular risk.In this article,the prevention measures of hypertension were analyzed and summarized through lifestyle interventions,mainly in the aspects of daily diet and exercise management. | YE Zhenhua Oscar Wager Fong DU Furong WU Yinping HUANG Lei | 2016 | 中西医结合护理(中英文)2016，2，11： | 0 |
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