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| 1 | HBx-DNA probe preparation and its application in study of hepatocarcinogenesis显示文摘HBxDNAprobepreparationanditsapplicationinstudyofhepatocarcinogenesisGAOFengGuang,SUNWenSheng,CAOYingLin,ZHANGLiNing,SON... | GAO FengGuang, SUN WenSheng, CAO YingLin, ZHANG LiNing, SONG Jing, LI HuaFen and YAN ShiKunKeywords hepatitis B virus liver neoplasms/etiology carcinoma, hepatocellular/etiology DNA probe | 1998 | World Journal of Gastroenterology1998，4，4： | 12 |
| 2 | Progression of diabetic retinopathy: the Beijing Eye Study显示文摘当在工作人口 worldwide.This 学习的视觉缺陷和盲目的一个领先的原因试图估计频率并且在北京眼睛学习是的基于人口的 setting.Methods 在题目把医生的前进的因素与已知的糖尿病联系了,背景糖尿病的 retinopathy (医生)出现了基于的学习在更大的北京执行了的一张人口在在场的 2001 和 2006 .The ,调查在 2001 与已知的糖尿病 mellitus 包括了所有题目,参予了后续 e ( 30 ) 51 使遭到在 2001 显示出医生的症状并且是在 2006,36 的 re-examined ( 21.2 )使遭到(与在基线在场的医生一起的 18 个题目,与在 2006 的最新诊断的医生一起的 18 个题目)在 follow-up.Progression 期间显示出医生的前进医生与农村区域被联系(机会比率(或): 5.43 , P0.001 )并且自我报导的动脉的高血压( OR:3.85 , P0.023 ) .In 非进步的亚群,医生的存在与教育的不同层次被联系(中学,中学,学院或更高, OR:0. | TU Ying XU Liang WEI Wen-bin WANG Shuang WANG Ya-xing Jost B Jonas | 2011 | Chinese Medical Journal2011，，22： | 7 |
| 3 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 4 | High performance liquid chromatographic separation of thirteen drugs collected in Chinese Pharmacopoeia 2010(Ch.P2010) on cellulose ramification chiral stationary phase显示文摘The enantiomers separation of thirteen drugs collected in Ch.P2010 was performed on chiral stationary phase of cellulose ramification (chiralpak OD and chiralpak OJ) by high performance liquid chromatographic (HPLC) methods, which included ibuprofen (C1), ketoprofen (C2), nitrendipine (C3), nimodipine (C4), felodipine (C5), omeprazole (C6), praziquantel (C7), propranolol hydrochloride (C8), atenolol (C9), sulpiride (C10), clenbuterol hydrochloride (C11), verapamil hydrochloride (C12), and chlorphenamine maleate (C13). The mobile phase consisted of isopropanol and n-hexane. The detection wavelength was set at 254 nm and the fiow rate was 0.7 mL/min. The enantiomers separation of these thirteen racemates on chiralpak OD column and chiralpak OJ column was studied, while the effects of proportion of organic additives, alcohol displacer and temperature on the separation were studied. And the mechanism of some of racemates was discussed. The results indicated that thirteen chiral drugs could be separated onchiral stationary phase of cellulose ramification in normal phase chromatographic system. The chromatographic retention and resolution of enantiomers could be adjusted by factors including column temperature and the concentration of alcohol displacer and organic alkaline modifier in mobile phase. It was shown that the resolution was improved with reducing concentration of alcohol displacer. When concentration of organic alkaline modifier was 0.2% (v/v), the resolution and the peak shape were fairly good. Most racemates mentioned above had better resolution at column temperature of 25 1C. When racemates were separated, the temperature should be kept so as to obtain stable separation results. | Ying Zhoua,b, Chao Maa, Yan Wanga, Qi-Ming Zhangb, Yi-Ying Zhanga, Jie Fua, Hong Gaoc, Li-Xun Zhaoc aState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China bNational Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China cInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China | 2012 | Journal of Pharmaceutical Analysis2012，2，1： | 4 |
| 5 | Effect of Sr on microstructure and aging behavior of Mg-14Li alloys | Bin Jiang a,b,c,Ying Zeng b,Hengmei Yin a,b,Ruihong Li a,b,Fusheng Pan a,b a National Engineering Research Center for Magnesium Alloys,Chongqing University,Chongqing 400030,China b College of Materials Science and Engineering,Chongqing University,Chongqing 400030,China c New Materials Center,Chongqing Academy of Science and Technology,Chongqing 401123,China | 2012 | Progress in Natural Science:Materials International2012，22，2： | 3 |
| 6 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 7 | Hemolysis of PM_(10) on RBCs in vitro:An indoor air study in a coal-burning lung cancer epidemic area显示文摘Epidemiological studies have suggested that inhalation exposure to indoor ambient air from coal-burning environments is causally associated with respiratory health risks.In order to explore the toxicological mechanisms behind the adverse health effects,the hemolytic activity of PM_(10)(particulate matter with an aerodynamic diameter of 10 um or less)samples collected from homes burning coal in the recognized China'cancer village'Xuanwei were evaluated and matched against their trace elemental contents.The results demonstrated that the hemolytic activity of indoor PM_(10) in coal-burning environments ranged from 4.28%to 5.24%,with a clear positive dose-response relationship.Although low dose samples exhibited a reduced hemolytic activity,PM_(10) could have a toxic effect upon people in a coal-burning indoor environment for extended time periods.The concentrations of analyzed trace elements in PM_(10) samples ranged from 6966 to 12,958 ppm.Among the analyzed elements,Zn,Ti,Ni,Cu,Pb,Ba,Mn,Cr and V were found at higher concentrations and accounted for over 95%of the total elements.The concentrations of total analyzed elements in the PM_(10) samples revealed a significant positive correlation with PM_(10) hemolytic activity.Of the analyzed elements,Zn,Pb and Cs positively correlated with hemolysis,while Li,U and V negatively correlated with the hemolysis of human red blood cells(RBCs).Therefore,the heavy metal elements could be one of the main factors responsible for the hemolytic capacity of indoor PM_(10) in coal-burning environments. | Mengyuan Zhang Longyi Shao Tim Jones Ying Hu Rachel Adams Kelly BéruBé | 2022 | Geoscience Frontiers2022，13，1： | 2 |
| 8 | Realization of laser textured brass surface via temperature tuning for surface wettability transition显示文摘Superhydrophobic surfaces have attracted extensive interests and researches into their fundamentals and potential applications.Laser texturing provides the convenience to fabricate the hierarchical micro/nanostructures for superhydrophobicity.However,after laser texturing,long wettability transition time from superhydrophilicity to superhydrophobicity is a barrier to mass production and practical industrial applications.External stimuli have been applied to change the surface composition and/or the surface morphology to reduce wettability transition time.Herein,by temperature tuning,wettability transition of laser textured brass surfaces is investigated.Scanning electron microscopy and surface contact angle measurement are employed to characterize the surface morphology and wettability behavior of the textured brass surfaces.By low-temperature heating(100℃~150℃),partial deoxidation of the top Cu O layer occurs to form hydrophobic Cu_2O.Therefore,superhydrophobicity without any chemical coating and surface modification could be achieved in a short time.Furthermore,after low-temperature heating,the low adhesive force between the water droplet and the sample surface is demonstrated for the laser textured brass surface.This study provides a simple method to fabricate the micro/nanostructure surfaces with controllable wettability for the potential applications. | Huangping Yan Mohamed Raiz B Abdul Rashid Si Ying Khew Fengping Li Minghui Hong | 2017 | 光电工程2017，44，6： | 2 |
| 9 | Seed-mediated synthesis of branched gold nanoparticles with the assistance of citrate and their surface-enhanced Raman scattering properties显示文摘 | Zou X Q Ying E B Dong S J | 2006 | Nanotechnol2006，17，： | 1 |
| 10 | Efficient Global Optimization for Image Registration 显示文摘 | YING C RICHARD R B | 2002 | IEEE Trans on Knowledge and Data Engineering2002，14，1： | 1 |
| 11 | Multivariate classification office wines according to ageing time and brand based on amino acid pro- files显示文摘 | Shen F Ying Y B Li B B | 2011 | Food Chemistry2011，129，2： | 1 |
| 12 | Erectile function restoration after repair of resected cavernous nerves by adipose - derived stem cells combined with autologous vein graft in rats 显示文摘 | Ying C Hu W Cheng B | 2014 | Cell Mel Neurebio12014，34，3： | 1 |
| 13 | Blockade of CD40 - CD40 ligand Interactions protects against radiation induced pulmonary inflammation and fibrosis 显示文摘 | Adnan A Ying Z Raymond B | 1998 | Clin Immunol Immunopathol1998，89，3： | 1 |
| 14 | Preparation of Mo2C/HZSM-5 and its catalytic performance for the conversion of n-butane into aromatics显示文摘 | YUAN S DERANOUE-ABD HAMIDB S B LI Y YING P XIN Q DEROUANE E G LI C | 2002 | J Mol Catal A2002，184，12： | 1 |
| 15 | MyoD and Myf-5 differentially regulate the development of limb versus trunk skeletal muscle 显示文摘 | KABLAR B KRASTEL K YING C | 1997 | Development1997，124，23： | 1 |
| 16 | Effect of different doses of transforming growth factor-β1 on cartilage and subchondral bone in osteoarthritic temporomandibular joints 显示文摘 | Ying B Chen K Hu J | 2013 | Br J Oral Maxillofac Surg2013，51，3： | 1 |
| 17 | Delivery of kinesin spindle protein targeting siRNA in solid lipid nanoparticles to cellular models of tumor vasculature显示文摘 | Ying B Campbell RB | 2014 | Biochem Biophys Res Commun2014，446，2： | 1 |
| 18 | Effect of different doses of transforming growth factor-β1on cartilage and subchondral bone in osteoarthritic temporomandibular joints显示文摘 | Ying B Chen K Hu J | 2013 | Br J Oral Maxillofac Surg2013，51，3： | 1 |
| 19 | Super/ subcritical fluid chromatography chiral separations with macrocyclic glycopeptide stationary phases显示文摘 | Ying L Alain B Clifford R | 2002 | J Chromatogr A2002，978，： | 1 |
| 20 | Study of the mechanism for poly (p-phenylene) benzoxazole polymerization-A remarkable reaction pathway to make rigid-rod polymers显示文摘 | Ying H S Jerry P H Bruce B | 1998 | Macromolecules1998，31，： | 1 |
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