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| 1 | A study of quenched CuZnAl Alloy by positron显示文摘Cu-23 at.%Zn-11 at.% Al alloy has been studied by positron annihilation technique. It is shown that the defects in the alloy induced by quenching from the temperature above α-transformation are basically monovacancies, instead of other forms of defects. | WANG Jingcheng YOU Fuqiang YIN Junlin (Shanghai Iron and Steel Research Institute, Shanghai Baoshan Iron and Steel Cooperation, Shanghai Key Laboratory of Metal-Functional Materials, Shanghai 200940) TANG Xuefeng QI Jinlin (Tongji University, Shanghai 2 | 1999 | Nuclear Science and Techniques1999，10，1： | 2 |
| 2 | Polymeric micelles with glycolipid-like structure and multiple hydrophobic domains for mediating molecular targetdelivery of paclitaxel显示文摘 | YOU Jian HU Fuqiang DU Yongzhong | 2007 | Biomacromolecules2007，8，8： | 1 |
| 3 | Near-Infrared Light-Sensitive Liposomes for the Enhanced Photothermal Tumor Treatment by the Combination with Chemotherapy显示文摘 | Jian You Peizun Zhang Fuqiang Hu Yongzhong Du Hong Yuan Jiang Zhu Zuhua Wang Jialin Zhou Chun Li | 2014 | Pharmaceutical Research2014，，： | 1 |
| 4 | Game- theoretic design for robust H∞ filtering and deconvo- lution with consideration of known input 显示文摘 | You Fuqiang WANG Full GUAN Shouping | 2011 | IEEE Transactions on Automation Science and Engineer- ing2011，8，3： | 1 |
| 5 | Investigation of Corrosion Resistance Using Positron Annihilation for an Amorphous Alloy显示文摘An amorphous alloy with Ni-(17-19) at. pct P prepared by electrodeposition process was studied using positron annihilation technique (PAT) associated with X-ray diffraction and the measurement of corrosion rate. It is suggested that defect or the interface between precipitates and matrix is one of the important factors which decrease corrosion resistance of the alloy after crystallization. | Jingcheng WANG, Fuqiang YOU,Junlin YIN and Guohua GAO Testing Center, Shanghai Iron & Steel Research Institute, Shanghai Bao Steel Group Corporation, Shanghai City Key Laboratory of Metal Functional Materials, Shanghai 200940, China | 2001 | Journal of Materials Science & Technology2001，17，4： | 0 |
| 6 | Recent advances in electrochemical decontamination of perfluorinated compounds from water: a review显示文摘Per- and polyfluoroalkyl substances (PFAS) pose serious human health and environmental risks due to their persistence and toxicity. Among the available PFAS remediation options, the electrochemical approach is promising with better control. In this review, recent advances in the decontamination of PFAS from water using several state-of-the-art electrochemical strategies, including electro-oxidation, electro-adsorption, and electro-coagulation, were systematically reviewed. We aimed to elucidate their design principles, underlying working mechanisms, and the effects of operation factors (e.g., solution pH, applied voltage, and reactor configuration). The recent developments of innovative electrochemical systems and novel electrode materials were highlighted. In addition, the development of coupled processes that could overcome the shortcomings of low efficiency and high energy consumption of conventional electrochemical systems was also emphasized. This review identified several major knowledge gaps and challenges in the scalability and adaptability of efficient electrochemical systems for PFAS remediation. Materials science and system design developments are forging a path toward sustainable treatment of PFAS-contaminated water through electrochemical technologies. | Fuqiang Liu Shengtao Jiang Shijie You Yanbiao Liu | 2023 | Frontiers of Environmental Science & Engineering2023，17，2： | 0 |
| 7 | Are the stacking faults in Cu-Zn-Al able to trap positrons显示文摘The phase transformation of Cu-23 at.%Zn-11 at.% Al alloy from about 5℃ to 25℃ has been studied by means of the positron annihilation and transmission electron microscope. It is shown that the stacking faults in the alloy have no remarkable effect on the trapping of positrons. | WANG Jingcheng YOU Fuqiang YIN Junlin (Shanghai Iron and Steel Research Institute, Shanghai Baoshan Iron and steel Cooperation, Shanghai Key Laboratory of Metal-Functional Materials, Shanghai 200940) | 1999 | Nuclear Science and Techniques1999，10，1： | 0 |
| 8 | Sequence homolog-based molecular engineering for shifting the enzymatic pH optimum显示文摘Cell-free synthetic biology system organizes multiple enzymes(parts)from different sources to implement unnatural catalytic functions.Highly adaption between the catalytic parts is crucial for building up efficient artificial biosynthetic systems.Protein engineering is a powerful technology to tailor various enzymatic properties including catalytic efficiency,substrate specificity,temperature adaptation and even achieve new catalytic functions.However,altering enzymatic pH optimum still remains a challenging task.In this study,we proposed a novel sequence homolog-based protein engineering strategy for shifting the enzymatic pH optimum based on statistical analyses of sequence-function relationship data of enzyme family.By two statistical procedures,artificial neural networks(ANNs)and least absolute shrinkage and selection operator(Lasso),five amino acids in GH11 xylanase family were identified to be related to the evolution of enzymatic pH optimum.Site-directed mutagenesis of a thermophilic xylanase from Caldicellulosiruptor bescii revealed that four out of five mutations could alter the enzymatic pH optima toward acidic condition without compromising the catalytic activity and thermostability.Combination of the positive mutants resulted in the best mutant M31 that decreased its pH optimum for 1.5 units and showed increased catalytic activity at pH<5.0 compared to the wild-type enzyme.Structure analysis revealed that all the mutations are distant from the active center,which may be difficult to be identified by conventional rational design strategy.Interestingly,the four mutation sites are clustered at a certain region of the enzyme,suggesting a potential“hot zone”for regulating the pH optima of xylanases.This study provides an efficient method of modulating enzymatic pH optima based on statistical sequence analyses,which can facilitate the design and optimization of suitable catalytic parts for the construction of complicated cell-free synthetic biology systems. | Fuqiang Ma Yuan Xie Manjie Luo Shuhao Wang You Hu Yukun Liu Yan Feng Guang-Yu Yang | 2016 | Synthetic and Systems Biotechnology2016，1，3： | 0 |
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