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| 1 | The effects of vitamin E succinate on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells显示文摘AIM:Toinvestigate the effects of vitamin E succinate(VES)on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells.METHODS:After SGC-7901cells were treated with VESat different doses(5,10,20mg·L^-1)at different time,reverse transcription-PCR technique was used to detect the level of c-jun mRNA;Western Blot was applied to measure the expression of c-jun protein.RESULTS:After the cells were theated with VESat 20mg·L^-1for 3h,the expression rapidly reached its maximun that was3.5times of UT control(P<0.01).The level of c-jun mRNA was also increased following treatment of VESfor 6h.However the expression after treatment of VES at 5mg·L^-1for24h was 1.6tmes compared with UTcontrol(P<0.01),Western blot analysis showed that the level of c-jun protein was obviusly elevated in VES-treated SGC-7901cells at 20mg·L^-1for3h,The expression of c-jun protein was gradually increased after treatment of VES at 20mg·L^-1for3,6,12and24h,respectively,with an evident time-effect relationship.CONCONCLUSION:The levels of c-jun mRNA and protein in VES-treated SGC-7901cells were increased in a dose-and time-dependent manner;the expression of c-jun was prolonged by VES,indicating that c-jun is involvedin VES-induced apoptosis in SGC-7901 cells. | Yah Zhao Kun Wu Wei Xia Yu-Juan Shan Li-Jie Wu Department of Nutrition and Food Hygiene,Public Health School,Harbin Medical University,Harbin 150001,Heilongjiang Province,China Wei-Ping Yu Genetics Institute,Texas University of USA,Austin,USA | 2002 | World Journal of Gastroenterology2002，8，5： | 8 |
| 2 | Effect of TiN inclusions on the impact toughness of low-carbon micro,alloyed steel 显示文摘 | Yah W Shan Y Y Yang K | 2006 | Metallurgical and Materials Transactions2006，37，7： | 1 |
| 3 | Magnetic monolayer film of oleic acid-stabilized Fe304 particles fabricated via Langmuir-Blodgett technique 显示文摘 | Chongju Liu Yah Shan Kezheng Chen | 2009 | Thin Solid Films2009，518，： | 1 |
| 4 | Nested polymerase chain raction in the diagnosis of negative Ziehl-Neelsen stained Mycobaterium Tuberculosis fistula-in-ano:Report of four cases显示文摘 | Shan YS Yah JJ Syedgar D | 2002 | Dieases of the Colon & Rectum2002，45，： | 1 |
| 5 | Generation of optical vortices via hehcal phase spatial filtering 显示文摘 | Guo Cheng- Shan Zhang Yah Han Yu - Jing | 2006 | Optics Communications2006，259，2： | 1 |
| 6 | Sequence Analysis and Phylogeny of Deer(Cervidae) mtDNA Control Regions显示文摘 | SHI Yah feng SHAN Xiang nian LI Jian | 2004 | Aeta Genetiea Sinica2004，31，4： | 1 |
| 7 | Semiparametric Additive Intensity Model with Frailty for Recurrent Events显示文摘有趋于增加的脆弱的精液的艇长比例的紧张模型是在科学研究分析经常遇到的周期性的事件数据的一条流行途径。在违背比例的紧张假设的情况中,添加剂紧张模型是一种有用选择。添加剂和比例的紧张模型为学习在风险因素和疾病复发之间的协会提供二个主要框架。然而,有脆弱的添加剂紧张模型上的方法论开发正在缺乏,尽管将珍贵。在这份报纸,我们与添加剂脆弱建议一个添加剂紧张模型提出效果可能周期性的事件象一样上的时间依赖者 covariates 在被脆弱变量捕获的周期性的事件以内评估 intra 班依赖。为在脆弱分发的回归参数和协会参数的 asymptotic 性质被建立。而且,我们也为累积基线紧张功能调查评估者的大样品的性质。 | Yah Yah LIU Yuan Shan WU | 2011 | Acta Mathematica Sinica,English Series2011，27，9： | 1 |
| 8 | Investigation analysis of the close contacts with smear positive TB patient 显示文摘 | Han WQ Shan LJ Yah YF | 2007 | Chinese Medical Science and Health2007，4，11： | 1 |
| 9 | Experimental studies on concrete filled steel tubes under high strain rate load-lng显示文摘 | XIAO Yah SHAN Jian-hua ZHENG Qiu | 2009 | ournal of Material in Civil Engineering (ASCE)2009，21，10： | 1 |
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