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| 1 | Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows显示文摘Known as the‘third polar region’,the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there.Previous studies of birds,animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence.The adaptive processes during the initial phase of highland adaptation remain poorly understood.We studied a human commensal,the Eurasian Tree Sparrow,which has followed human agriculture to the Qinghai-Tibet Plateau.Despite strong phenotypic differentiation at multiple levels,in particular in muscle-related phenotypes,highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years.In a one-month acclimation experiment investigating phenotypic plasticity,we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes.Through population genetic analyses,we identified a signature of polygenic adaptation,whereby shifts in allele frequencies are spread across multiple loci,many of which are associated with muscle-related processes.Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution,shedding light on early stages of adaptive evolution to a novel environment. | Yanhua Qu Chunhai Chen Ying Xiong Huishang She Yong E Zhang Yalin Cheng Shane DuBay Dongming Li Per G P Ericson Yan Hao Hongyuan Wang Hongfeng Zhao Gang Song Hailin Zhang Ting Yang Chi Zhang Liping Liang Tianyu Wu Jinyang Zhao Qiang Gao Weiwei Zhai Fumin Lei | 2020 | National Science Review2020，7，1： | 2 |
| 2 | CD34-Hematopoietic stem cells:current concepts andcontroversies显示文摘 | Yalin G Michael L Monika E | 2003 | Stem Cells2003，21，1： | 1 |
| 3 | Brugada type 1 electrocardiogram unmasked by a febrile state following syncope显示文摘 | Yalin K Gtilctik E Bilqe A K | 2012 | Turk Kardiyol Dern Ars2012，40，2： | 1 |
| 4 | The effects of various cooling strategies on surface roughness and tool wear during soft materials milling显示文摘 | YALIN B OZGUR A E KORU M | 2009 | Materials & Design2009，30，3： | 1 |
| 5 | Infarct characteristics by CMR identifies suhstrate for monomorphic VT in post-MI pa- tients with relatively preserved systolic function and ns-VT显示文摘 | Yalin K Golcuk E Buyukhayrak H | 2014 | Pacing Clin Electrophysiol2014，37，4： | 1 |
| 6 | Usefulness of T (peak) -T (end) interval to distinguish arrhythmogenic right ventricular cardiomyopathy from idiopathic right ven- tricular outflow tract tachycardia显示文摘 | Golcuk E Yalin K Kaya Bilge A | 2014 | Pacing Clin Electro- physiol2014，37，12： | 1 |
| 7 | Inception of Sediment Transport 显示文摘 | Yalin M Karahan E | 1979 | Journal of Hydraulic Divisition ASCE1979，105，11： | 1 |
| 8 | Sonographic assessment of ceftriaxone-associated biliary pseudolithiasis in children显示文摘 | Palanduz A Yalin I Tongu E | 2000 | J Clin Ultrasound2000，28，4： | 1 |
| 9 | Experimental Confir-mation of 3- and 5 Scroll Attractors from a Generalized Chua's Cir- cuit显示文摘 | Yalin M E Suykens J A K Vandewalle J | 2000 | IEEE Transactions on Circuits and Systems-part h Funda- mental Theory and Applications2000，47，3： | 1 |
| 10 | Inception of sediment transport显示文摘 | Yalin M S Karahan E | 1979 | Journal of the Hydraulics Division1979，105，11： | 1 |
| 11 | Mandibular bone necrosis caused by use of arsenic paste during endodontic treatment: two case reports 显示文摘 | Yavuz MS Kaya GS Yalin E | 2008 | Int Endod J2008，41，7： | 1 |
| 12 | Inception of sediment transport 显示文摘 | Yalin M Karahan E | 1979 | Journal of Hydraulic Division ASCE1979，105，11： | 1 |
| 13 | CD34 - Hematopoietic stem cells : current concepts and controversies 显示文摘 | Guo Yalin Michael L Monika E | 2003 | Stem Cells2003，21，1： | 1 |
| 14 | Inception of sediment transport 显示文摘 | YALIN M S KARAHAN E | 1979 | Journal of the Hydraulics Division1979，105，11： | 1 |
| 15 | Mandibular bone nec-rosis caused by use of arsenic paste during endodontic treat-ment: two case reports 显示文摘 | Yavuz M S Kaya G S Yalin E | 2008 | Int Endod J2008，41，7： | 1 |
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