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| 1 | Sentinel lymph node navigation surgery for early stage gastric cancer显示文摘We attempted to evaluate the history of sentinel node navigation surgery(SNNS),technical aspects,tracers,and clinical applications of SNNS using Infrared Ray Electronic Endoscopes(IREE)combined with Indocyanine Green(ICG).The sentinel lymph node(SLN)is defined as a first lymph node(LN)which receives cancer cells from a primary tumor.Reports on clinical application of SNNS for gastric cancers started to appear since early 2000s.Two prospective multicenter trials of SNNS for gastric cancer have also been accomplished in Japan.Kitagawa et al reported that the endoscopic dual(dye and radioisotope)tracer method for SN biopsy was confirmed acceptable and effective when applied to the early-stage gastric cancer(EGC).We have previously reported the usefulness of SNNS in gastrointestinal cancer using ICG as a tracer,combined with IREE(Olympus Optical,Tokyo,Japan)to detect SLN.LN metastasis rate of EGC is low.Hence,clinical application of SNNS for EGC might lead us to avoid unnecessary LN dissection,which could preserve the patient’s quality of life after operation.The most ideal method of SNNS should allow secure and accurate detection of SLN,and real time observation of lymphatic flow during operation. | Norio Mitsumori Hiroshi Nimura Naoto Takahashi Masahiko Kawamura Hiroaki Aoki Atsuo Shida Nobuo Omura Katsuhiko Yanaga | 2014 | World Journal of Gastroenterology2014,20,19: | 15 |
| 2 | Prediction of lymph node metastasis and sentinel node navigation surgery for patients with early-stage gastric cancer显示文摘Accurate prediction of lymph node(LN) status is crucially important for appropriate treatment planning in patients with early gastric cancer(EGC). However,consensus on patient and tumor characteristics associated with LN metastasis are yet to be reached. Through systematic search,we identified several independent variables associated with LN metastasis in EGC,which should be included in future research to assess which of these variables remain as significant predictors of LN metastasis. On the other hand,even if we use these promising parameters,we should realize the limitation and the difficulty of predicting LN metastasis accurately. The sentinel LN(SLN) is defined as first possible site to receive cancer cells along the route of lymphatic drainage from the primary tumor. The absence of metastasis in SLN is believed to correlate with the absence of metastasis in downstream LNs. In this review,we have attempted to focus on several independent parameters which have close relationship between tumor and LN metastasis in EGC. In addition,we evaluated the history of sentinel node navigation surgery and the usefulness for EGC. | Atsuo Shida Norio Mitsumori Hiroshi Nimura Yuta Takano Taizou Iwasaki Muneharu Fujisaki Naoto Takahashi Katsuhiko Yanaga | 2016 | World Journal of Gastroenterology2016,22,33: | 13 |
| 3 | Laparoscopic versus open D2 gastrectomy for advanced gastric cancer: a retrospective cohort study显示文摘 | Toshihiko Shinohara Seiji Satoh Seiichiro Kanaya Yoshinori Ishida Keizo Taniguchi Jun Isogaki Kazuki Inaba Katsuhiko Yanaga Ichiro Uyama | 2013 | Surgical Endoscopy2013,,1: | 3 |
| 4 | The efficiency of micrometastasis by sentinel node navigation surgery using indocyanine green and infrared ray laparoscopy system for gastric cancer显示文摘 | Kentaro Yano Hiroshi Nimura Norio Mitsumori Naoto Takahashi Hideyuki Kashiwagi Katsuhiko Yanaga | 2012 | Gastric Cancer2012,,3: | 3 |
| 5 | Hepatic reconstruction from fetal porcine liver cells using a radial flow bioreactor显示文摘AIM: To examine the efficacy of the radial flow bioreactor (RFB) as an extracorporeal bioartificial liver (BAL) and the reconstruction of liver organoids using embryonic pig liver cells. METHODS: We reconstructed the liver organoids using embryonic porcine liver cells in the RFB. We also determined the gestational time window for the optimum growth of embryonic porcine liver cells. Five weeks of gestation was designated as embryonic day (E) 35 and 8 wk of gestation was designated as E56. These cells were cultured for one week before morphological and functional examinations. Moreover, the efficacy of pulsed administration of a high concentration hepatocyte growth factor (HGF) was examined. RESULTS: Both cell growth and function were excellent after harvesting on E35. The pulsed administration of a high concentration of HGF promoted the differentiation and maturation of these fetal hepatic cells. Microscopic examination of organoids in the RFB revealed palisading and showed that bile duct-like structures were well developed, indicating that the organoids were mini livers. Transmission electron microscopy revealed microvilli on the luminal surfaces of bile duct-like structures and junctional complexes, which form the basis of the cytoskeleton of epithelial tissues. Furthermore, strong expression of connexin (Cx) 32, which is the main protein of hepatocyte gap junctions, was observed. With respect to liver function, ammonia detoxification and urea synthesis were shown to be performed effectively. CONCLUSION: Our system can potentially be applied in the fields of BAL and transplantation medicine. | Yuji Ishii Ryota Saito Hideki Marushima Ryusuke Ito Taro Sakamoto Katsuhiko Yanaga | 2008 | World Journal of Gastroenterology2008,14,17: | 3 |
| 6 | Combined use of T2-weighted and diffusion-weighted 3-T MR imaging for differentiating uterine sarcomas from benign leiomyomas显示文摘 | Tomohiro Namimoto Yasuyuki Yamashita Kazuo Awai Takeshi Nakaura Yumi Yanaga Toshinori Hirai Tetsuo Saito Hidetaka Katabuchi | 2009 | European Radiology2009,,: | 2 |
| 7 | Role of diffusion-weighted imaging in the diagnosis of gynecological diseases显示文摘 | Tomohiro Namimoto Kazuo Awai Takeshi Nakaura Yumi Yanaga Toshinori Hirai Yasuyuki Yamashita | 2009 | European Radiology2009,,3: | 2 |
| 8 | Sentinel node mapping with indocyanine green (ICG) and infrared ray detection in early gastric cancer: An accurate method that enables a limited lymphadenectomy显示文摘 | W. Kelder H. Nimura N. Takahashi N. Mitsumori G.M. van Dam K. Yanaga | 2010 | European Journal of Surgical Oncology2010,,6: | 2 |
| 9 | Validity of modified gastrectomy combined with sentinel node navigation surgery for early gastric cancer显示文摘 | Hironori Ohdaira Hiroshi Nimura Norio Mitsumori Naoto Takahashi Hideyuki Kashiwagi Katsuhiko Yanaga | 2007 | Gastric Cancer2007,,2: | 2 |
| 10 | Crypreserved cultured epidermal allograits achieved early closure of wounds and reduced scar formation in deep partialthickness bum wounds (DDB)and spit-thickness skin donor sites of pediatric patients 显示文摘 | Yanaga H Udoh Y Yamauchi T | 2001 | Bums2001,27,7: | 1 |
| 11 | A nation nide incidence smTey of kawasaki disease in 1985-1986 in Japen显示文摘 | Yanaga wa H Nakamura Y Yashiro M | 1988 | J lnfect Disease1988,156,: | 1 |
| 12 | A new suppressive agent against interleukin-1 beta and tumor necrosis factor-alpha enhances liver regeneration after partial hepatectomy in rats显示文摘 | Hou Z Yanaga K Kamohara Y | 2003 | Hepatol Res2003,26,1: | 1 |
| 13 | Isolated hepatic caudate lobectomy显示文摘 | Yanaga K Matsumata T Hayashi H | 1994 | Surgery1994,115,2: | 1 |
| 14 | The advantages and disadvan- tages of a Roux-en-Y reconstruction after a distal gastrectomy for gastric cancer 显示文摘 | Hoya Y Mitsumori N Yanaga K | 2009 | Surg Today2009,39,8: | 1 |
| 15 | Percutaneous transhepatic mechanical thrombectomy for acute mesenteric venous thrombosis 显示文摘 | Takahashi N Kuroki K Yanaga K | 2005 | J Endovasc Ther2005,12,4: | 1 |
| 16 | Alternate hemihepatic vascular control technique for hepatic resection显示文摘 | Yanaga K Matsumata T Nishizaki T | 1993 | Am J Surg1993,165,4: | 1 |
| 17 | Successful treatment of advanced gallbladder cancer with an anticancer drug S-1: assessment based on intratumoral gene显示文摘 | Kumiko Kitajima Susumu Kobayashi Hiroaki Shiba Tadashi Uwagawa Yuichi Ishida Keisuke Aiba Makio Kawakami Katsuhiko Yanaga | 2008 | International Journal of Clinical Oncology2008,,6: | 1 |
| 18 | Laparoscopic hepatic resection for hepatocellular carcinoma 显示文摘 | Hashizumel M Takenaka K Yanaga K | 1995 | Surg1995,9,12: | 1 |
| 19 | Amelioration of liver injury by ischemic preconditioning显示文摘 | Yoshizumi T Yanaga K Soejima Y | 1998 | Br J Sur1998,85,12: | 1 |
| 20 | Generating ears from cultured autologous auricular chondrocytes by using two-stage implantation in treatment of microtia显示文摘 | YANAGA H IMAI K FUJIMOTO T | 2009 | Plast Reconstr Surg2009,124,3: | 1 |