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| 1 | MiR-33a suppresses breast cancer cell proliferation and metastasis by targeting ADAM9 and ROS1显示文摘MicroRNAs (miRNAs ) 是由指向多重 mRNAs 的定序明确地在基因表示的 post-transcriptional 规定有一个枢轴的角色的小 noncoding RNA。尽管 miR-33a 最近被报导在类脂化合物动态平衡,动脉粥样硬化,和肝的纤维变性起一个重要作用,在肿瘤前进和转移的 miR-33a 的功能大部分是未知的。这里,我们发现在乳癌纸巾的 downregulated miR-33a 与淋巴节点转移相关。MiR-33a 表示比 noncancerous 胸在高度变形的乳癌房间线是显著地更低的上皮的房间和非变形的乳癌房间。而且,在变形乳癌细胞的 miR-33a 的 overexpression 显著地减少在 vitro 并且显著地的细胞增长和侵略在 vivo 禁止肿瘤生长和肺转移,而它的在非变形的乳癌细胞击倒显著地在 vitro 提高细胞增长和侵略并且在 vivo 支持肿瘤生长和肺转移。联合生物信息学预言和生物化学的分析,我们证明 ADAM9 和 ROS1 是 miR-33a 的直接下游的目标。这些调查结果作为乳癌房间增长和转移的一个否定管理者识别了 miR-33a。 | Chuankai Zhang Yunda Zhang Weiji Ding Yancheng Lin Zhengjie Huang Qi Luo | 2015 | Protein & Cell2015，6，12： | 10 |
| 2 | Ultra-sensitive flexible Ga_(2)O_(3)solar-blind photodetector array realized via ultra-thin absorbing medium显示文摘The quest for solar-blind photodetectors with outstanding optoelectronic properties and weak signals detection capability is essential for their applications in the field of imaging,communication,warning,etc.To date,Ga_(2)O_(3)has demonstrated potential for high-performance solar-blind photodetectors.However,the performance usually decays superlinearly at low light intensities due to carrier-trapping effect,which limits the weak signal detection capability of Ga_(2)O_(3)photodetectors.Herein,a Ga_(2)O_(3)solarblind photodetector with ultra-thin absorbing medium has been designed to restrain trapping of photo-generated carriers during the transporting process by shortening the carrier transport distance.Meanwhile,multiple-beam interference is employed to enhance the absorption efficiency of the Ga_(2)O_(3)layer using an Al/Al_(2)O_(3)/Ga_(2)O_(3)structure.Based on the ultra-thin absorbing medium with enhanced absorption efficiency,a 7×7 flexible photodetector array is developed,and the detectivity can reach 1.7×10^(15)Jones,which is among the best values ever reported for Ga_(2)O_(3)photodetectors.Notably,the performance of the photodetector decays little as the illumination intensity is as weak as 5 nW/cm2,revealing the capacity to detect ultra-weak signals.In addition,the flexible photodetector array can execute the functions of imaging,spatial distribution of light source intensity,real-time light trajectory detection,etc.Our results may provide a route to high-performance solar-blind photodetectors for ultra-weak light detection. | Yancheng Chen Xun Yang Yuan Zhang Xuexia Chen Junlu Sun Zhiyang Xu Kaiyong Li Lin Dong Chongxin Shan | 2022 | Nano Research2022，15，4： | 1 |
| 3 | Fabry-Perot interference and piezo-phototronic effect enhanced flexible MoS_(2) photodetector显示文摘Flexible photodetectors(PDs)are indispensable components for next-generation wearable electronics.Recently,two-dimensional(2D)materials have been implemented as functional flexible optoelectronic devices due to their characteristics of atomically thin layers,excellent flexibility,and strain sensitivity.In this work,we developed a flexible photodetector based on MoS_(2)/NiO heterojunction,and Fabry-Perot(F-P)and piezo-phototronic effect have been employed to enhance the responsivity(R)and external quantum efficiency(EQE)of the devices.The F-P effect is utilized to improve the optical absorption of the MoS_(2),resulting in an enhancement in the photoluminescence(PL)of monolayer MoS_(2) and the EQE of the photodetector by 30 and 130 times,respectively.The flexible photodetector exhibits an ultrahigh detectivity(D*)of 2.6×10^(14) Jones,which is the highest value ever reported for flexible MoS_(2) PDs.The piezo-potential of monolayer MoS_(2) decreases the valence band offset at the interface of MoS_(2)/NiO,which increases the transfer efficiency of the photon-generated carriers significantly.Under 1.17%tensile strain,the R of the flexible photodetector can be enhanced by 271%.This research may provide a universal strategy for the design and performance optimization of 2D materials heterostructures for flexible optoelectronics. | Xuexia Chen Xun Yang Qing Lou Yuan Zhang Yancheng Chen Yacong Lu Lin Dong Chong-Xin Shan | 2022 | Nano Research2022，15，5： | 1 |
| 4 | Ultrasensitive broadband position-sensitive detector based on graphitic carbon nitride显示文摘As a typical two-dimensional material,graphitic carbon nitride(g-CN)has attracted great interest because of its distinctive electronic,optical,and catalytic properties.However,the absence of a feasible route toward large-area and high-quality films hinders its development in optoelectronics.Herein,high-quality g-CN films have been grown on Si substrate via a vapor-phase transport-assisted condensation method.The g-CN/Si heterojunction shows an obvious response to ultraviolet–visible-near infrared photons with a responsivity of 133 A·W−1,which is two orders of magnitude higher than the best value ever reported for g-CN photodetectors.A position-sensitive detector(PSD)has been developed using the lateral photovoltaic effect of the g-CN/Si heterojunction.The PSD shows a wide response spectrum ranging from 300 to 1,100 nm,and a position sensitivity and rise/decay time of 395 mV·mm−1 and 3.1/50μs,respectively.Moreover,the application of the g-CN/Si heterojunction photodetector in trajectory tracking and acoustic detection has been realized for the first time.This work unveils the potential of g-CN for large-area photodetectors,and prospects for their applications in trajectory tracking and acoustic detection. | Xuexia Chen Xun Yang Qing Lou Yongzhi Tian Zhiyu Liu Chaofan Lv Yancheng Chen Lin Dong Chong-Xin Shan | 2023 | Nano Research2023，16，1： | 0 |
| 5 | Ga2O3 solar-blind position-sensitive detectors显示文摘Monoclinic Ga2O3(β-Ga2O3)is a promising material for achieving solar-blind photodetection because of its unique characteristics,including its high breakdown electric field,radiation hardness,thermal and chemical stabilities,and intrinsic visible/solar-blind properties.Until now,several studies have investigated the development of high-performanceβ-Ga2O3 solar-blind photodetectors.However,these photodetectors can only detect the light intensity but not the light position.In this work,fourquadrant position-sensitive detectors(4Q-PSDs)were developed and demonstrated based onβ-Ga2O3.4Q-PSDs,comprising four identical metal-semiconductor-metal-structured photodetector components,demonstrate high uniformity,large signal-tonoise ratio,good ultraviolet/visible rejection ratio,and fast response/recovery time.Subsequently,the position of the illumination beam can be determined by analyzing the output signals of the four photodetector components.This work may indicate the promising application potential of the Ga2O3-based photodetectors in the fields of positioning,aligning,and monitoring the solarblind beams. | Kaiyong Li Xun Yang Yongzhi Tian Yancheng Chen Chaonan Lin Zhenfeng Zhang Zhiyang Xu Jinhao Zang Chongxin Shan | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，11： | 0 |
| 6 | A study on the Chinese beliefs and their effects on small and medium sized business after 1990显示文摘As a result of economic reform commencing in 1978 in China, cultural beliefs of the Chinese business owners are changing. While much has been published concerning large and multinational businesses, there is a gap in knowledge of cultural beliefs of small and medium sized enterprises. To provide new knowledge, a survey on these smaller sized enterprises located throughout China was conducted in the summer of 2006. Respondents were selected from urban and rural areas, coastal and inland provinces and various industries to provide information on their opinions on how some of their cultural beliefs have changed from 1990 to present. Specif ic beliefs questioned include: Use of fengshui, Traditional Forbidden Activities, Company Naming Responsibility, Company Name Basis, Use of Numbers, Use of Physiognomy, and Prediction of a Company's Future. The importance of fengshui has risen over in the last sixteen years and certain traditional forbidden activities such as not turning over the f ish while eating has remained important as a cultural belief. Naming a company is important and the desirability of a good name is based on various factors. Use of numbers, physiognomy, and non-scientifi c methods for predicting the future success of companies are of lesser use. These aspects of culture are reviewed in consideration of the change from a planned economy to a market-based economy. | Kenneth Wall Zhang Runtong Yang Yancheng Lin Hua | 2008 | Ecological Economy2008，4，3： | 0 |
| 7 | Trophic gauntlet effects on fisheries recovery:a case study in Sansha Bay,China显示文摘Low biological productivity causes ecosystem energy deficiency.Sansha Bay is an important spawning and nursery ground for migratory fish in the East China Sea(ECS).There is significant mariculture in this area,but stock enhancement programs and seasonal fishery closures have failed to recover populations of the commercially important species,Larimichthys crocea.We want to figure out the potential reason of unsuccessful L.crocea resource in recent 30 years.In this study,the trophic status of L.crocea,the food source proportions of L.crocea and zooplankton,and the food web structure and functioning of Sansha Bay was analyzed.A high nutrient low chlorophyll phenomenon was observed:this prevented harmful algal blooms,and phytoplankton growth was restrained by intensive macroalgal culture,resulting in a low abundance of zooplankton in Sansha Bay.Phytoplankton was the most important food source of zooplankton,and zooplankton was the greatest food source of juvenile L.crocea.Analyzed L.crocea suffered from starvation.Crucially,most of the phytoplankton was not used efficiently in the Sansha Bay ecosystem.This study suggests that trophic bottleneck,caused by food limitation,is a potential reason for unsuccessful fishery recovery in enclosed bay with macroalgal culture. | Bin Xie Cheng Huang Ya Wang Xijie Zhou Guogan Peng Yancheng Tao Jiaju Huang Xiaoqing Lin Lingfeng Huang | 2021 | Ecosystem Health and Sustainability2021，7，1： | 0 |
| 8 | Multiple Pesticide Residues in Bananas Sold in Tangshan City and Dietary Risk Assessment显示文摘[Objectives]This study was conducted to investigate the pesticide residue status of bananas in Tangshan area and the dietary intake risk of consumers.[Methods]High-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)was applied to detect 70 pesticide residues in 191 batches of banana samples extracted from Tangshan area,and chronic and acute risk assessments were conducted.[Results]Among the 191 batches of bananas,172 batches of samples were detected to contain agrochemicals,with a detection rate of 90.05%.Seventeen agrochemicals were detected,accounting for 24.29%of the total agrochemicals tested.There was a phenomenon of multiple pesticide residues in a single sample,and high detection rates were found in carbendazim(49.21%),prochloraz(41.88%),pyraclostrobin(34.03%)and imidacloprid(30.37%).According to GB 2763-2021 National Food Safety Standards—Maximum Residue Limits for Pesticides in Food,the over-standard rate of imidacloprid was 17.8%;and the chronic and acute dietary risks of the 17 pesticide residues were all less than 100%.[Conclusions]The pesticide residues in bananas consumed by consumers on a daily basis do not pose unacceptable dietary risks. | Lin LI Huihui LIU Hefeng ZHANG Yancheng ZHOU Yuping LIU Zhenguo ZHANG Qianqian CONG Liang ZHANG Yajing WANG Ling ZHENG Baiqin ZHENG | 2023 | Agricultural Biotechnology2023，12，6： | 0 |
| 9 | Tight gas charging and accumulation mechanisms and mathematical model显示文摘The gas-water distribution and production heterogeneity of tight gas reservoirs have been summarized from experimental and geological observations, but the charging and accumulation mechanisms have not been examined quantitatively by mathematical model. The tight gas charging and accumulation mechanisms were revealed from a combination of physical simulation of nuclear magnetic resonance coupling displacement, numerical simulation considering material and mechanical equilibria, as well as actual geological observation. The results show that gas migrates into tight rocks to preferentially form a gas saturation stabilization zone near the source-reservoir interface. When the gas source is insufficient, gas saturation reduction zone and uncharged zone are formed in sequence from the source-reservoir interface. The better the source rock conditions with more gas expulsion volume and higher overpressure, the thicker the gas saturation stabilization and reduction zones, and the higher the overall gas saturation. When the source rock conditions are limited, the better the tight reservoir conditions with higher porosity and permeability as well as larger pore throat, the thinner the gas saturation stabilization and reduction zones, but the gas saturation is high. The sweet spot of tight gas is developed in the high-quality reservoir near the source rock, which often corresponds to the gas saturation stabilization zone. The numerical simulation results by mathematical model agree well with the physical simulation results by nuclear magnetic resonance coupling displacement, and reasonably explain the gas-water distribution and production pattern of deep reservoirs in the Xujiaweizi fault depression of the Songliao Basin and tight gas reservoirs in the Linxing-Huangfu area of the Ordos Basin. | ZHOU Nengwu LU Shuangfang ZHANG Pengfei LIN Zizhi XIAO Dianshi LU Jiamin ZHU Yingkang LIU Yancheng LIN Liming WANG Min JIANG Xinyu LIU Yang WANG Ziyi LI Wenbiao | 2023 | Petroleum Exploration and Development2023，50，6： | 0 |
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