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| 1 | Controlling factors on the submarine canyon system: A case study of the Central Canyon System in the Qiongdongnan Basin, northern South China Sea显示文摘Based on an integrated analysis of high-resolution 2D/3D seismic data and drilling results, this study analyzes the tectonicsedimentary evolution of the Qiongdongnan Basin(QDNB) since the late Miocene, and discusses the controlling factors on the formation and development of the Central Canyon System(CCS). The sediment failures caused by the relative sea level falling might have discharged deposits from the slope to the canyon. The two suits of the infillings, i.e., turbidites and mass transport complex(MTC), were derived from the northwestern source and northern source, respectively. The sediment supplies, which differ significantly among different areas, might have led to the variations observed in the internal architectures. Tectonic transformation around 11.6 Ma had provided the tectonic setting for the CCS and formed an axial sub-basin in the central part of the Changchang Depression, which could be called the rudiment of the CCS. The tectonic activity of the Red River Fault(RRF) at about 5.7 Ma might have strengthened the hydrodynamics of the deposits at the junction of the Yinggehai Basin(YGHB) and the QDNB to trigger a high-energy turbidity current. The MTC from the northern continental slope system might have been constrained by the Southern Uplift, functioning as a barrier for the infillings of the CCS. Thanks to a sufficient sediment supply during the Holocene period and the paleo-seafloor morphology, the relief of modern central canyon with the starving landform in the eastern Changchang Depression might have been accentuated by deposition of sediments and vertical growth along the canyon flanks, where collapse deposits were widely developed. Corresponding to the segmentation of the CCS, the forming mechanisms of the canyon between the three segments would be different. The turbidite channel in the head area had likely been triggered by the abundant sediment supply from the northwestern source together with the fault activity at about 5.7 Ma of the RRF. The formation and evolution of the canyon in the western segment were caused by combined effects of the turbidite channel from the northwestern source, the MTC from the northern continental slope, and the paleo-seafloor geomorphology. In the eastern segment, the canyon was constrained by the tectonic transformation occurring at approximately 11.6 Ma and the insufficient sediment supply from the wide-gentle slope. | SU Ming ZHANG Cheng XIE XiNong WANG ZhenFeng JIANG Tao HE YunLong ZHANG CuiMei | 2014 | Science China Earth Sciences2014，57，10： | 21 |
| 2 | Astronomical tuning and magnetostratigraphy of Neogene biogenic reefs in Xisha Islands, South China Sea显示文摘Biogenic reefs are one of two major depositional types in the South China Sea, and are constructed by coral, algae and bryozoa. The West Pacific is a major area of biogenic reef development and plays a critical role in the global carbon cycle. However, the lack of geochronological studies in previous works inhibits our understanding of their contributions. Herein, we conduct a cyclostratigraphic and magnetostratigraphic study on Neogene biogenic reefs using the XK–1 core that was drilled at the Shidao Island,Xisha(Paracel) Islands. The main findings of this study are:(1) the establishment of reliable magentostratigraphy for Ledong, Huangliu, Meishan and Sanya Formations;(2) the magnetic susceptibility variation can be inferred as growth index and tuned to the 405–ka long eccentricity cycle;(3) the astronomical geochronology suggests that the bottom ages for Ledong, Yinggehai, Huangliu, Meishan,and Sanya Formations are 2.2 Ma, 5.7 Ma, 10.4 Ma, 16.6 Ma, and 24.3 Ma, respectively; and (4) Earth's eccentricity and obliquity played predominant roles in biogenic reef establishment on orbital to tectonic timescales. Thus, the reported geochronology offers an opportunity to test the contributions of various factors and hypothesize their roles in the global carbon cycle in future. | Liang Yi Zhimin Jian Xinyu Liu Youhua Zhu Daojun Zhang Zhenfeng Wang Chenglong Deng | 2018 | Science Bulletin2018，63，9： | 12 |
| 3 | An effective method for improving the accuracy of Argo objective analysis显示文摘基于南船座数据的最佳的插值目的分析,改进被做到广泛地在数据吸收和客观分析系统使用的一个背景错误协变性矩阵的实验公式。明确地,关联的一个评价可伸缩那能有效地改善南船座客观分析的精确性被开发了。这个方法能自动地适应一个变量的坡度变化并且被叫作坡度依赖者关联规模方法。它南船座客观分析上的效果与 Gaussian 脉搏和光谱分析理论上被验证。一个维的模拟实验的结果证明坡度依赖者关联规模能改进客观分析系统的适应性,为充分吸收在有更大的海洋学的坡度的区域的观察的短波信息的分析计划使它可能。新计划在太平洋被用于南船座数据目的分析系统。结果显然被改进。 | ZHANG Chunling XU Jianping BAO Xianwen WANG Zhenfeng | 2013 | Acta Oceanologica Sinica2013，32，7： | 11 |
| 4 | Structure and kinematic analysis of the deepwater area of the Qiongdongnan Basin through a seismic interpretation and analogue modeling experiments显示文摘Located at the northwest continental slope of the South China Sea, the Qiongdongnan Basin bears valley-shaped bathymetry deepening toward east. It is separated from the Yinggehai Basin through NW-trending Indo-ChinaRed River shear zone, and connected with NW subsea basin through the Xisha Trough. Along with the rapid progress of the deepwater exploration, large amounts of high resolution geophysical and geological data were accumulated. Scientific researches about deepwater basins kept revealing brand new tectonic and sedimentary discoveries. In order to summarize the structural features and main controlling factors of the deepwater Qiongdongnan Basin, a series of researches on basin architecture, fault activities, tectonic deformation and evolution were carried out. In reference to analogue modeling experiments, a tectonic situation and a basin formation mechanism were discussed. The researches indicate that: the northern boundary of the Qiongdongnan Basin is strongly controlled by No. 2 fault. The overlapping control of two stress fields from the east and the west made the central depression zone extremely thinned. Combined with the changed stress field, the segmentation of a preexisting weakness zone made the sags in the east experiencing different rifting histories from the west ones. The NE-trending west segment of the Qiongdongnan Basin experienced strong rifting during Eocene, while the roughly EW-trending sags in the east segment show strong rifting during late Eocene and early Oligocene.Local structures such as NW-trending basal fault and inherited uplifts controlled the lateral segmentation. So first order factors such as regional stress field and preexisting weakness zone controlled the basin zonation, while the second order factors determined the segmentation from east to west. | SUN Zhen WANG Zhenfeng SUN Zhipeng WANG Zhangwen ZHANG Wei HE Lijuan | 2015 | Acta Oceanologica Sinica2015，34，4： | 10 |
| 5 | New insights on the origin of the basement of the Xisha Uplift,South China Sea显示文摘The study of basement geochronology provides crucial insights into the tectonic evolution of oceans. However, early studies on the basement of the Xisha Uplift were constrained by limited geophysical and seismic data; Xiyong1 was the only commercial borehole drilled during the 1970 s because of the huge thickness of overlying Cenozoic strata on the continental margin. Utilizing two newly-acquired basement samples from borehole XK1, we present petrological analysis and zircon uranium(U)-lead(Pb) isotope dating data in this paper that enhance our understanding of the formation and tectonic features of the Xisha Uplift basement. Results indicate that this basement is composed of Late Jurassic amphibole plagiogneisses that have an average zircon 206 Pb/238 U age of 152.9±1.7 Ma. However, the youngest age of these rocks, 137±1 Ma, also suggests that metamorphism termination within the Xisha basement occurred by the Early Cretaceous. These metamorphic rocks have adamellites underneath them which were formed by magmatic intrusions during the late stage of the Early Cretaceous(107.8±3.6 Ma). Thus, in contrast to the Precambrian age(bulk rubidium(Rb)-strontium(Sr) analysis, 627 Ma) suggested by previous work on the nearby Xiyong1 borehole, zircons from XK1 are likely the product of Late Mesozoic igneous activity. Late Jurassic-Early Cretaceous regional metamorphism and granitic intrusions are not confined to Xisha; rocks have also been documented from areas including the Pearl River Mouth Basin and the Nansha Islands(Spratly Islands) and thus are likely closely related to large-scale and long-lasting subduction of the paleo-Pacific plate underneath the continental margins of East Asia, perhaps the result of closure of the Meso-Tethys in the South China Sea(SCS). Controversies remain as to whether, or not, the SCS region developed initially on a uniform Precambrian-aged metamorphic crystalline basement. It is clear, however, that by this time both Mesozoic compressive subduction and Cenozoic rifting and extension had significantly modified the original basement of the SCS region. | ZHU WeiLin XIE XiNong WANG ZhenFeng ZHANG DaoJun ZHANG ChengLi CAO LiCheng SHAO Lei | 2017 | Science China Earth Sciences2017，60，12： | 10 |
| 6 | Geology and hydrocarbon accumulations in the deepwater of the northwestern South China Sea——with focus on natural gas显示文摘The deepwater of the northwestern South China Sea is located in the central to southern parts of the Qiongdongnan Basin(QDN Basin),which is a key site for hydrocarbon exploration in recent years.In this study,the authors did a comprehensive analysis of gravity-magnetic data,extensive 3D seismic survey,cores and cuttings,paleontology and geochemical indexes,proposed the mechanism of natural gas origin,identified different oil and gas systems,and established the model of hydrocarbon accumulations in the deep-water region.Our basin tectonic simulation indicates that the evolution of QDN Basin was controlled by multiple-phased tectonic movements,such as Indochina-Eurasian Plate collision,Tibetan Uplift,Red River faulting and the expansion of the South China Sea which is characterized by Paleogene rifting,Neogene depression,and Eocene intensive faulting and lacustrine deposits.The drilling results show that this region is dominated by marineterrestrial transitional and neritic-bathyal facies from the early Oligocene.The Yacheng Formation of the early Oligocene is rich in organic matter and a main gas-source rock.According to the geological-geochemical data from the latest drilling wells,Lingshui,Baodao,Changchang Sags have good hydrocarbon-generating potentials,where two plays from the Paleogene and Neogene reservoirs were developed.Those reservoirs occur in central canyon structural-lithologic trap zone,Changchang marginal trap zone and southern fault terrace of Baodao Sag.Among them,the central canyon trap zone has a great potential for exploration because the various reservoirforming elements are well developed,i.e.,good coal-measure source rocks,sufficient reservoirs from the Neogene turbidity sandstone and submarine fan,faults connecting source rock and reservoirs,effective vertical migration,late stage aggregation and favorable structural–lithological composite trapping.These study results provide an important scientific basis for hydrocarbon exploration in this region,evidenced by the recent discovery of the significant commercial LS-A gas field in the central canyon of the Lingshui Sag. | WANG Zhenfeng SUN Zhipeng ZHANG Daojun ZHU Jitian LI Xushen HUANG Baojia GUO Minggang JIANG Rufeng | 2015 | Acta Oceanologica Sinica2015，34，10： | 9 |
| 7 | Asymmetric Transfer and Pressure Hydrogenation with Earth-Abundant Transition Metal Catalysts显示文摘 | Zhenfeng Zhang Nicholas Andrew Butt Muxing Zhou Delong Liu Wanbin Zhang | 2018 | Chinese Journal of Chemistry2018，36，5： | 8 |
| 8 | Synthesis,functionalization,and nanomedical applications of functional magnetic nanoparticles显示文摘Synthesis of magnetic nanoparticles(MNPs) is one of the most active research areas in advanced materials. MNPs that have magnetic properties and other functionalities have been demonstrated to show great promise in nanomedical applications. This review summarizes the current MNPs preparation,functionalization and stabilization methods. It also analyzes the detailed features of MNPs. And furthermore it highlights some actual case analyses of these MNPs for disease therapy, drug delivery,hyperthermia, bioseparation and bioimaging applications. | Zhou Chen Cao Wu Zhenfeng Zhang Wangping Wu Xuefeng Wang Zhiqiang Yu | 2018 | Chinese Chemical Letters2018，29，11： | 7 |
| 9 | Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling显示文摘室的肥大是心血管的疾病的事件的一个强大、独立的预言者。低剂量的乙酰水杨酸酸(阿司匹林) 的脉管的性质通过血小板 cyclooxygenase 的不可逆的抑制提供心血管的好处 1;然而,可能的 anti-hypertrophic 性质和阿司匹林的潜在的机制没详细被调查。在这研究,健康野类型的雄的老鼠随机被划分成三个组并且使遭到了到横向的大动脉的收缩(TAC ) 或假冒的操作。操作 TAC 的老鼠与低剂量的阿司匹林的人的等价物被对待(10 mg 吗? | Samuel Chege Gitau Xuelian Li Dandan Zhao Zhenfeng Guo Haihai Liang Ming Qian Lifang Lv Tianshi Li Bozhi Xu Zhiguo Wang Yong Zhang Chaoqian Xu Yanjie Lu Zhiming Du Hongli Shan Baofeng Yang | 2015 | Frontiers of Medicine2015，9，4： | 6 |
| 10 | Identity Based Threshold Proxy Signature显示文摘 | XU Jing ZHANG Zhenfeng FENG Dengguo | 2006 | Chinese Journal of Electronics2006，15，1： | 6 |
| 11 | Evolution of deepwater sedimentary environments and its implication for hydrocarbon exploration in Qiongdongnan Basin, northwestern South China Sea显示文摘Over the past several years, a number of hydrocarbon reservoirs have been discovered in the deepwater area of Qiongdongnan Basin, northwestern South China Sea. These oil/gas fields demonstrate that the evolution of the deepwater sedimentary environment are controlling the formation and distribution of large-scale clastic reservoirs. Integration between seismic and borehole data were necessary to best clarify the distribution and quality of these deepwater reservoirs. Geochemical and paleobiological evidence from discrete samples was also applied to document specific information regarding the sedimentary environment. Results show that the Qiongdongnan Basin has existed as a thriving marine environment since Oligocene, when several rifting depressions developed throughout the entire Qiongdongnan Basin. Triggered by the faults activities, several distinct provenances supplied the coarse sediments, transporting and depositing them in deep parts of the rifting depressions. A fan delta system then formed nearby the source in the deeper area of these rifting depressions. The sedimentary environment of Qiongdongnan gradiationally became deepwater since early Miocene.Consequently, abundances of sediments were transported from Hainan Island and Southern Uplift, and then sunk into the basin center. The submarine fans revealed by many boreholes in this area verified them as good reservoir. Because the area reached its lowest sea level at late Miocene and the Southern Uplift subsidenced under sea level, not providing any sediment, so that the carbonate mesa and biorhythms characteristic of this area also developed during this period. In the west part of Qiongdongnan Basin, sediments transported from Vietnam increased in response to the Tibetan Uplift. Consequently, a central canyon developed along the center of Qiongdongnan Basin, which has been confirmed by several boreholes as a favorable hydrocarbon reservoir. The clarification of the deepwater sedimentary environment's evolution is potentially highly beneficial to future hydrocarbon exploration in the deepwater area of Qiongdongnan Basin. | WANG Zhenfeng JIANG Tao ZHANG Daojun WANG Yahui ZUO Qianmei HE Weijun | 2015 | Acta Oceanologica Sinica2015，34，4： | 6 |
| 12 | Controlling effects of differential swelling index on evolution of coal permeability显示文摘Coal permeability measurements are normally conducted under the assumption that gas pressure in the matrix is equalized with that in fracture and that gas sorption-induced swelling/shrinking strain is uniformly distributed within the coal.However,the validity of this assumption has long been questioned and differential strain between the fracture strain and the bulk strain has long been considered as the primary reason for the inconsistency between experimental data and poroelasticity solutions.Although efforts have been made to incorporate the impact into coal permeability models,the fundamental nature of those efforts to split the matrix strain between fracture and coal bulk remains questionable.In this study,a new concept of differential swelling index(DSI)was derived to theoretically define the relation among sorption-induced strains of the coal bulk,fracture,and coal matrix at the equilibrium state.DSI was a function of the equilibrium pressure and its magnitudes were regulated by the Langmuir constants of both the matrix and the coal bulk.Furthermore,a spectrum of DSI-based coal permeability models was developed to explicitly consider the effect of differential strains.These models were verified with the experimental data under the conditions of uniaxial strain,constant confining pressure,and constant effective stress. | Chuanzhong Jiang Zhenfeng Zhao Xiwei Zhang Jishan Liu Derek Elsworth Guanglei Cui | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，3： | 5 |
| 13 | Hypertrophic adenoids in patients with nasopharyngeal carcinoma:appearance at magnetic resonance imaging before and after treatment显示文摘Introduction:Patients with nasopharyngeal carcinoma(NPC) sporadically develop abnormal adenoids.Nasopharyngeal adenoids are usually included in the gross tumor volume(GTV) but may have different therapeutic responses than tumor tissue.Therefore,distinguishing adenoids from tumor tissue may be required for precise and efficient chemoradiotherapy and radiotherapy.We characterized nasopharyngeal adenoids and investigated the therapeutic responses of NPC and nasopharyngeal adenoids using magnetic resonance imaging(MRI).Methods:MRI data from 40 NPC patients with a coexisting adenoid mass before and after treatment were analyzed.The features of the adenoid masses,including location,striped appearance,size,interface,symmetry/asymmetry,and cysts,were evaluated.Treatment response were scored according to the World Health Organization guidelines.Results:A striped appearance was observed in 36 cases before treatment and in all cases after treatment.In these 36 cases,the average GTVs including and excluding the uninvolved adenoids were 19.8 cm^3 and 14.8 cm^3,respectively.The average percentage change after excluding the uninvolved adenoids from the GTV was 31.0%.Stable disease in the adenoids was identified in 27(96.4%) of 28 patients after neoadjuvant chemotherapy,while NPC clearly regressed.Partial adenoid responses were identified in 33(82.5%) of 40 patients at 3 months after chemoradiotherapy or radiotherapy,whereas complete tumor responses were achieved in all patients.Six months after treatment,the adenoids continued to atrophy but did not disappear,and tumor recurrence was not found.Conclusions:Nasopharyngeal adenoids and carcinoma tissue in NPC patients can be distinguished by using MRI and have different responses to chemoradiotherapy and radiotherapy.These findings contribute to better delineating the GTV of NPC,based on which spatially optimized strategies can be developed to render precise and efficient chemoradiotherapy and radiotherapy.Additionally,we observed a clear difference in the responses of these two tissue types to current therapies.This finding may reduce or avoid unnecessary biopsies or overtreatment. | Yao-Pan Wu Pei-Qiang Cai Li Tian Jie-Hua Xu Richard Alan Mitteer Jr Yi Fan Zhenfeng Zhang | 2015 | Chinese Journal of Cancer2015，34，3： | 4 |
| 14 | Nonlinear relationship between enteric-coated mycophenolate sodium dose and mycophenolic acid exposure in Han kidney transplantation recipients显示文摘The aim of the research was to investigate the pharmacokinetics(PK) of enteric-coated mycophenolate sodium(EC-MPS) by quantification of the active metabolite of mycophenolic acid(MPA)after multiple escalating oral doses in Han kidney transplant recipients. A total of 28 Han postoperative kidney transplant recipients were given a multiple-dose of 540, 720 or 900 mg of EC-MPS two times a day in combination with tacrolimus for 6 days. Blood specimens were collected at each time point from0 to 12 h after EC-MPS administration. MPA plasma concentrations were measured by UPLC–UV. The relationship between the EC-MPS dose and its PK parameters was assessed. In the range from 540 to900 mg, C_(max) and AUC_(0–12h) did not increase with dose escalation. The AUC_(0–12h), C_(max), C_0 and T_(max) for the 540 720 and 900 mg doses were not significantly different, respectively(P 40.05). AUC_0–12 h and C_(max) were increased less than proportionally with increasing EC-MPS dose levels. Inter-individual variability in AUC_(0–12h), C_(max) and C_0 were considerable. Nonlinear PK relationships were found from the doses of 540–900 mg of EC-MPS. | Jun Zhang Mengmeng Jia Lihua Zuo Na Li Yonggang Luo Zhi Sun Xiaojian Zhang Zhenfeng Zhu | 2017 | Acta Pharmaceutica Sinica B2017，7，3： | 3 |
| 15 | Changes in progenitors and differentiated epithelial cells of neonatal piglets显示文摘This study aimed to assess the changes of small intestinal morphology,progenitors,differentiated epithelial cells,and potential mechanisms in neonatal piglets.Hematoxylin and eosin staining of samples from 36 piglets suggested that dramatic changes were observed in the jejunum crypts depth and crypt fission index of neonatal piglets(P<0.001).The number of intestinal stem cells(ISC)tended to increase(P<0.10),and a decreased number of enteroendocrine cells appeared in the jejunal crypt on d 7(P<0.05).Furthermore,the mRNA expression of jejunal chromogranin A(ChgA)was down-regulated in d 7 piglets(P<0.05).There was an up-regulation of the adult ISC marker gene of SPARC related modular calcium binding 2(Smoc2),and Wnt/b-catenin target genes on d 7(P<0.05).These results were further verified in vitro enteroid culture experiments.A mass of hollow spheroids was cultured from the fetal intestine of 0-d-old piglets(P<0.001),whereas substantial organoids with budding and branching structures were cultured from the intestine of 7-d-old piglets(P<0.001).The difference was reflected by the organoid budding efficiency,crypt domains per organoid,and the surface area of the organoid.Furthermore,spheroids on d 0 had more Ki67-positive cells and enteroendocrine cells(P<0.05)and showed a decreasing trend in the ISC and goblet cells(P<0.10).Moreover,the mRNA expression of spheroids differed markedly from that of organoids,with low expression of intestinal differentiation gene(Lysozyme;P<0.05),epithelial-specific markers(Villin,E-cadherin;P<0.05),and adult ISC markers(leucine-rich repeat-containing G protein-coupled receptor 5[Lgr5],Smoc2;P<0.001),and upregulation of fetal marker(connexin 43[Cnx43];P<0.05).The mRNA expression of relevant genes was up-regulated,and involved in Wnt/b-catenin,epidermal growth factor(EGF),Notch,and bone morphogenetic protein(BMP)signaling on d 7 organoids(P<0.05).Spheroids displayed low differentiated phenotype and high proliferation,while organoids exhibited strong differentiation potential.These results indicated that the conversion from the fetal progenitors(spheroids)to adult ISC(normal organoids)might largely be responsible for the fast development of intestinal epithelial cells in neonatal piglets. | Lanmei Yin Jun Li Yitong Zhang Qing Yang Cuiyan Yang Zhenfeng Yi Yuebang Yin Qiye Wang Jianzhong Li Nengshui Ding Zhigang Zhang Huansheng Yang Yulong Yin | 2022 | Animal Nutrition2022，，1： | 3 |
| 16 | Subtyping of type A influenza by sequencing the variable regions of HA gene specifically amplified with RT-PCR显示文摘The outbreak of a novel influenza A(H1N1) virus across the globe poses a threat to human health.It is of paramount importance to develop a rapid,reliable and inexpensive diagnostic procedure.Based on the bioinformatic information from public database,primers specific for influenza A virus surface protein haemagglutinin(HA) of several subtypes(including H1,H2,H3,H5,H7 and H9) were designed.Primer-specific PCR products were subjected to sequencing for accurately distinguishing H1 and H3 subtypes from others.This sequencing-based detection method will not only be applied to rapid detection and simultaneous subtype identification of new influenza A virus H1N1,but also provide the strategies to monitor other new types ofinfluenza virus with explosive potential. | YAN An DING GuoHui ZHOU ZhenFeng DONG Hui ZHANG YaKun ZHU Lei HE YunGang ZHANG GuoQing LI YiXue SUN Bing HUANG Zhong LAN Ke JIN Li WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang DAI JianXin GUO YaJun WANG Hao CHE XiaoYan WU Fan YUAN ZhenGan ZHANG Xi CAO ZhiWei ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi ZHAO GuoPing JIN WeiRong XIONG Hui | 2009 | Chinese Science Bulletin2009，54，13： | 3 |
| 17 | Interleukin-6 signaling pathway in targeted therapy for cancer显示文摘 | Yuqi Guo Feng Xu TianJian Lu Zhenfeng Duan Zhan Zhang | 2012 | Cancer Treatment Reviews2012，，7： | 2 |
| 18 | Archaeal chromatin proteins显示文摘Archaea, along with Bacteria and Eukarya, are the three domains of life. In all living cells, chromatin proteins serve a crucial role in maintaining the integrity of the structure and function of the genome. An array of small, abundant and basic DNA-binding proteins, considered candidates for chromatin proteins, has been isolated from the Euryarchaeota and the Crenarchaeota, the two major phyla in Archaea. While most euryarchaea encode proteins resembling eukaryotic histones, crenarchaea appear to synthesize a number of unique DNA-binding proteins likely involved in chromosomal organization. Several of these proteins (e.g., archaeal histones, Sac10b homologs, Sul7d, Cren7, CC1, etc.) have been extensively studied. However, whether they are chromatin proteins and how they function in vivo remain to be fully understood. Future investiga- tion of archaeal chromatin proteins will lead to a better understanding of chromosomal organization and gene expression in Archaea and provide valuable information on the evolution of DNA packaging in cellular life. | ZHANG ZhenFeng GUO Li HUANG Li | 2012 | Science China(Life Sciences)2012，55，5： | 2 |
| 19 | Comprehensive Analysis and Optimization of Dynamic Vibration-Absorbing Structures for Electric Vehicles Driven by In-Wheel Motors显示文摘Distributed-drive electric vehicles(EVs)replace internal combustion engine with multiple motors,and the novel configura-tion results in new dynamic-related issues.This paper studies the coupling effects between the parameters and responses of dynamic vibration-absorbing structures(DVAS)for EVs driven by in-wheel motors(IWM).Firstly,a DVAS-based quarter suspension model is developed for distributed-drive EVs,from which nine parameters and five responses are selected for the coupling effect analysis.A two-stage global sensitivity analysis is then utilized to investigate the effect of each parameter on the responses.The control of the system is then converted into a multiobjective optimization problem with the defined system parameters being the optimization variables,and three dynamic limitations regarding both motor and suspension subsystems are taken as the constraints.A particle swarm optimization approach is then used to either improve ride comfort or mitigate IWM vibration,and two optimized parameter sets for these two objects are provided at last.Simulation results provide in-depth conclusions for the coupling effects between parameters and responses,as well as a guideline on how to design system parameters for contradictory objectives.It can be concluded that either passenger comfort or motor lifespan can be reduced up to 36%and 15%by properly changing the IWM suspension system parameters. | Yechen Qin Zhenfeng Wang Kang Yuan Yubiao Zhang | 2019 | Automotive Innovation2019，2，4： | 2 |
| 20 | Universally composable anonymous password authenticated key exchange显示文摘Anonymous password authenticated key exchange(APAKE) is an important cryptographic primitive, through which a client holding a password can establish a session key with a server both authentically and anonymously. Although the server is guaranteed that the client in communication is from a pre-determined group, but the client's actual identity is protected. Because of their convenience, APAKE protocols have been widely studied and applied to the privacy protection research. However, all existing APAKE protocols are handled in stand-alone models and do not adequately settle the problem of protocol composition, which is a practical issue for protocol implementation. In this paper, we overcome this issue by formulating and realizing an ideal functionality for APAKE within the well-known universal composability(UC) framework, which thus guarantees security under the protocol composition operations. Our formulation captures the essential security requirements of APAKE such as off-line dictionary attack resistance, client anonymity and explicit mutual authentication. Moreover, it addresses the arbitrary probabilistic distribution of passwords. The construction of our protocol, which utilizes SPHF-friendly commitments and CCA2-secure encryption schemes, can be instantiated and proven secure in the standard model, i.e., without random oracle heuristics. | Xuexian HU Jiang ZHANG Zhenfeng ZHANG Jing XU | 2017 | Science China(Information Sciences)2017，60，5： | 2 |
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