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| 1 | Comparison of corrosion behavior of ZL104 alloy at as-cast and heat treatment states显示文摘The corrosion behavior of ZL104 alloy at different states(as-cast and heat treatment) in salt spray corrosion (SSC) was studied.The results show that the sample treated after refinement and modifciation has the least corrosive resistance compared with the sample bearing as -cast stucure at the beginning of the corrosion.As the corrosion process continued.however,the trend reversed itself.After 44h continuous corrosion,the corrosive rates of all samples tend to be stable.After experiments,the sample bearing as -cast structure had the most corrosive products on the surface whereas the sample being refined and modified had the least products.The Fourier transformation infrared spectroscopy(FTIR) analyses of the corrosion products show that these products are composed of hydroxyl-containing substances. | WANG Donghui, ZHENG Yankang, LI ianguo, and BAI BingzheDepartment of Materials Science and Engineering, Tsinghua University, Beijing 100084, China | 2002 | Rare Metals2002，21，3： | 4 |
| 2 | Effect of furan π-bridge on the photovoltaic performance of D-A copolymers based on bi(alkylthio-thienyl)benzodithiophene and fluorobenzotriazole显示文摘The medium band gap donor-acceptor(D-A) copolymer J61 based on bi(alkylthio-thienyl)benzodithiophene as donor unit and fluorobenzotriazole as acceptor unit and thiophene as π-bridge has demonstrated excellent photovoltaic performance as donor material in nonfullerene polymer solar cells(PSCs) with narrow bandgap n-type organic semiconductor ITIC as acceptor.For studying the effect of π-bridges on the photovoltaic performance of the D-A copolymers,here we synthesized a new D-A copolymer J61-F based on the same donor and acceptor units as J61 but with furan π-bridges instead of thiophene.J61-F possesses a deeper the highest occupied molecular orbital(HOMO) level at-5.45 eV in comparison with that(-5.32 eV) of J61.The non-fullerene PSCs based on J61-F:ITIC exhibited a maximum power conversion efficiency(PCE) of 8.24%with a higher open-circuit voltage(V_(oc)) of 0.95 V,which is benefitted from the lower-lying HOMO energy level of J61-F donor material.The results indicate that main chain engineering by changing π-bridges is another effective way to tune the electronic energy levels of the conjugated D-A copolymers for the application as donor materials in non-fullerene PSCs. | Tinghai Yan Haijun Bin Yankang Yang Lingwei Xue Zhi-Guo Zhang Yongfang Li | 2017 | Science China Chemistry2017，60，4： | 1 |
| 3 | LncRNAs LCETRL3 and LCETRL4 at chromosome 4q12 diminish EGFR-TKIs efficiency in NSCLC through stabilizing TDP43 and EIF2S1显示文摘Epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKIs)are effective targeted therapy drugs for advanced nonsmall cell lung cancer(NSCLC)patients carrying sensitized EGFR mutations.The rapid development of EGFR-TKIs resistance represents a major clinical challenge for managing NSCLC.The chromosome 4q12 is the first genome-wide association study(GWAS)-reported locus associated with progression-free survival(PFS)of NSCLC patients treated with EGFR-TKIs.However,the biological significance of the noncoding transcripts at 4q12 in NSCLC remains elusive.In the present study,we identified two 4q12 long noncoding RNAs(lncRNAs)LCETRL3 and LCETRL4 which could significantly dimmish EGFR-TKIs efficiency.In line with their oncogenic role,evidently higher LCETRL3 and LCETRL4 levels were observed in NSCLC tissues as compared with normal specimens.Importantly,lncRNA LCETRL3 can interact with oncoprotein TDP43 and inhibit ubiquitination and degradation of TDP43.Similarly,lncRNA LCETRL4 can bind and stabilize oncoprotein EIF2S1 through reducing ubiquitin-proteasome degradation of EIF2S1.In particular,elevated levels of LCETRL3 or LCETRL4 in NSCLC cells resulted in stabilization of TDP43 or EIF2S1,increased levels of NOTCH1 or phosphorylated PDK1,activated AKT signaling and,thus,EGFR-TKIs resistance.Taken together,our data revealed a novel model that integrates two lncRNAs transcribed from the 4q12 locus into the regulation of EGFR-TKIs resistance in NSCLC.These findings shed new light on the importance of functionally annotating lncRNAs in the GWAS loci and provided insights to declare novel druggable targets,i.e.,lncRNAs,which may unlock the therapeutic potential of EGFR-TKIs resistant NSCLC in the clinic. | Yankang Li Yue Shen Mengyu Xie Bowen Wang Teng Wang Jiajia Zeng Hui Hua Jinming Yu Ming Yang | 2022 | Signal Transduction and Targeted Therapy2022，7，2： | 1 |
| 4 | Heat shock factor 1 in fat biology: comments on ‘Local hyperthermia therapy induces browning of white fat and treats obesity’显示文摘Beige fat,a newly discovered adipose tissue featuring high functional flexibility,exhibits the characteristics of white fat at rest,but can be activated to function like brown fat under cold or β-adrenergic stimulation via a process termed‘browning of white fat’.This activation enables beige fat to greatly promote heat production and energy consumption,as well as to improve systemic glucose and lipid metabolism.Beige fat also exists in supraclavicular and paraspinal regions in human adults,which endows its great potential forintervention ofobesityandmetabolic diseases. | Lingyan Xu Yu Li Yankang Zhang Ting Zhang Dongmei Wang Xinran Ma | 2022 | Journal of Molecular Cell Biology2022，14，4： | 1 |
| 5 | Alkoxy substituted benzodithiophene-alt-fluorobenzotriazole copolymer as donor in non-fullerene polymer solar cells显示文摘A new benzodithiophene(BDT)-alt-fluorobenzotriazole(FBTA) D-A copolymer J40 was designed and synthesized by introducing 2-octyldodecyloxy side chains on its BDT units, for expanding the family of the BDT- alt-FBTA-based copolymers and investigating the side chain effect on the photovoltaic performance of the polymer in non-fullerene polymer solar cells(PSCs).J40 exhibits complementary absorption spectra and matched electronic energy levels with the n-type organic semiconductor(n-OS)(3,9-bis(2-methylene-(3-(1,1-dicyanomethylene)-indanone))-5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3-d:2′,3′-d′]-sindaceno[1,2-b:5,6-b′]dithiophene)(ITIC) acceptor, and was used as polymer donor in the non-fullerene PSCs with ITIC as acceptor. The power conversion efficiency(PCE) of the PSCs based on J40:ITIC(1:1, w/w) with thermal annealing at 120 °C for 10 min reached 6.48% with a higher open-circuit voltage(Voc) of 0.89 V. The high Voc of the PSCs is benefitted from the lower-lying highest occupied molecular orbital(HOMO) energy level of J40. Although the photovoltaic performance of the polymer J40 with alkoxy side chain is lower than that of J60 and J61 with alkylthio-thienyl conjugated side chains, the PCE of6.48% for the J40-based device is still a relatively higher photovoltaic efficiency in the non-fullerene PSCs reported so far. The results indicate that the family of the BDT-alt-FBTA-based D-A copolymers are high performance polymer donor materials for non-fullerene PSCs and the side chain engineering plays an important role in the design of high performance polymer donors in the non-fullerene PSCs. | Haijun Bin Lian Zhong Zhi-Guo Zhang Liang Gao Yankang Yang Lingwei Xue Jing Zhang Zhanjun Zhang Yongfang Li | 2016 | Science China Chemistry2016，59，10： | 1 |
| 6 | Intelligent 3D garment system of the human body based on deep spiking neural network显示文摘Background Intelligent garments,a burgeoning class of wearable devices,have extensive applications in domains such as sports training and medical rehabilitation.Nonetheless,existing research in the smart wearables domain predominantly emphasizes sensor functionality and quantity,often skipping crucial aspects related to user experience and interaction.Methods To address this gap,this study introduces a novel real-time 3D interactive system based on intelligent garments.The system utilizes lightweight sensor modules to collect human motion data and introduces a dual-stream fusion network based on pulsed neural units to classify and recognize human movements,thereby achieving real-time interaction between users and sensors.Additionally,the system incorporates 3D human visualization functionality,which visualizes sensor data and recognizes human actions as 3D models in real time,providing accurate and comprehensive visual feedback to help users better understand and analyze the details and features of human motion.This system has significant potential for applications in motion detection,medical monitoring,virtual reality,and other fields.The accurate classification of human actions contributes to the development of personalized training plans and injury prevention strategies.Conclusions This study has substantial implications in the domains of intelligent garments,human motion monitoring,and digital twin visualization.The advancement of this system is expected to propel the progress of wearable technology and foster a deeper comprehension of human motion. | Minghua JIANG Zhangyuan TIAN Chenyu YU Yankang SHI Li LIU Tao PENG Xinrong HU Feng YU | 2024 | 虚拟现实与智能硬件(中英文)2024，6，1： | 0 |
| 7 | BAINITE STRUCTURE IN Cu-Zn-Al ALLOY OBSERVED BY SCANNING TUNNELING MICROSCOPE显示文摘BAINITESTRUCTUREINCu-Zn-AlALLOYOBSERVEDBYSCANNINGTUNNELINGMICROSCOPE￥LiChunming;FangHongsheng;FengQingling;ZhengYankang(Depar... | Li Chunming Fang Hongsheng Feng Qingling Zheng Yankang(Department of Material Science and Engineering, Tsinghua Universitg,Beijing 100084)Yan, Junjue(Beijing universitg,Beijing,100871)Abstact:The bainite structurc in a Cu-25.9Zn-4.0Al-0.1Re (wt.-%) allo | 1994 | 中国有色金属学会会刊:英文版1994，4，4： | 0 |
| 8 | Effects of Si Content and the Addition Amount of Al-3B Master Alloy on the Solidification Structures of Hypoeutectic Al-Si Alloys显示文摘Effects of Si content and the addition amount of Al-3B master alloy on the solidification structures of hypo- eutectic Al-Si alloys were studied. The addition amounts of the master alloy were 0.2%, 0.4%, 0.7% and 1% (mass frac- tion, so as the follows), respectively. The Si content of Al-Si binary alloys investigated varied from 1% to 11%. The ob- servation of macrostructures of non-refined samples showed that 3% Si constitutes a transition point at which the mini- mum grain size can be obtained. It was also found that Al-3B master alloy can shift the transition point towards a higher Si value when its addition amount increases, making this point appear at 4%, 5% and 6% Si as its addition amount incre- ases up to 0.4%, 0.7% and 1%, respectively. | Donghui Wang,Jianguo Li, Yankang Zheng, Bingzhe Bai Department of Materials Science and Engineering, Tsinghua University, Beijing 100084, China | 2001 | Rare Metals2001，20，3： | 0 |
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