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| 1 | The China Alzheimer Report 2022显示文摘China’s population has rapidly aged over the recent decades of social and economic development as neurodegenerative disorders have proliferated,especially Alzheimer’s disease(AD)and related dementias(ADRD).AD’s incidence rate,morbidity,and mortality have steadily increased to make it presently the fifth leading cause of death among urban and rural residents in China and magnify the resulting financial burdens on individuals,families and society.The‘Healthy China Action’plan of 2019-2030 promotes the transition from disease treatment to health maintenance for this expanding population with ADRD.This report describes related epidemiological trends,evaluates the economic burden of the disease,outlines current clinical diagnosis and treatment status and delineates existing available public health resources.More specifically,it examines the public health impact of ADRD,including prevalence,mortality,costs,usage of care,and the overall effect on caregivers and society.In addition,this special report presents technical guidance and supports for the prevention and treatment of AD,provides expertise to guide relevant governmental healthcare policy development and suggests an information platform for international exchange and cooperation. | Rujing Ren Jinlei Qi Shaohui Lin Xinya Liu Peng Yin Zhihui Wang Ran Tang Jintao Wang Qiang Huang Jianping Li Xinyi Xie Yongbo Hu Shishuang Cui Yuan Zhu Xiaoping Yu Pengfei Wang Yikang Zhu Yiran Wang Yanyan Huang Yisong Hu Ying Wang Chunbo Li Maigeng Zhou Gang Wang | 2022 | General Psychiatry2022，35，1： | 20 |
| 2 | m6A RNA modification controls autophagy through upregulating ULK1 protein abundance显示文摘 | Shouheng Jin Xiya Zhang Yanyan Miao Puping Liang Kaiyu Zhu Yuanchu She Yaoxing Wu Di-Ao Liu Junjiu Huang Jian Ren Jun Cui | 2018 | Cell Research2018，28，9： | 12 |
| 3 | A Hybrid Deep Sea Navigation System of LBL/DR Integration Based on UKF and PSO-SVM显示文摘In order to improve the navigation accuracy of human occupied vehicle(HOV)precisely and efficiently,an innovative hybrid approach based on unscented Kalman filter(UKF)and support vector machine(SVM)is proposed to fuse integrated navigation data.HOV is generally equipped with long baseline(LBL)acoustic positioning system and dead reckoning(DR)as an integrated navigation system.UKF is adopted to estimate the state of the dynamic model because of its good performance in filtering nonlinear problems.An accurate and stable filtering result can be obtained when both LBL and DR are online.At the same time,SVM is utilized to train DR information with the result when LBL outrages,and the particle swarm optimization(PSO)algorithm is employed for SVM parameters optimization.Therefore,the integrated navigation system can maintain a good performance when the LBL is off-line.Simulation results with the real navigation data of Jiaolong HOV show that the methodology proposed here is able to meet the needs of HOV application. | LIU Ben LIU Kaizhou WANG Yanyan ZHAO Yang CUI Shengguo WANG Xiaohui | 2015 | 机器人2015，37，5： | 7 |
| 4 | Estimation of Ecological Water Requirements Based on Habitat Response to Water Level in Huanghe River Delta,China显示文摘In recent years,wetland ecological water requirements (EWRs) have been estimated by using hydrological and functional approaches,but those approaches have not yet been integrated for a whole ecosystem.This paper presents a new method for calculating wetland EWRs,which is based on the response of habitats to water level,and determines water level threshold through the functional integrity of habitats.Results show that in the Huanghe (Yellow) River Delta water levels between 5.0 m and 5.5 m are required to maintain the functional integrity of the wetland at a value higher than 0.7.One of the dominant plants in the delta,Phragmites australis,tolerates water level fluctuation of about ± 0.25 m without the change in wetland functional integrity.The minimum,optimum and maximum EWRs for the Huanghe River Delta are 9.42×106 m3,15.56×106 m3 and 24.12×106 m3 with water levels of 5.0 m,5.2 m and 5.5 m,corresponding to functional integrity indices of 0.70,0.84 and 0.72,respectively.A wetland restoration program has been performed,which aims to meet these EWRs in attempt to recover from losses of up to 98% in the delta's former wetland area. | CUI Baoshan HUA Yanyan WANG Chongfang LIAO Xiaolin TAN Xuejie TAO Wendong | 2010 | Chinese Geographical Science2010，20，4： | 7 |
| 5 | Efficacy and safety of repetitive transcranial magnetic stimulation for generalised anxiety disorder: A metaanalysis显示文摘Background Pharmacological and conventional nonpharmacological treatments are only moderately effective in treatingeneralised anxiety disorder(GAD).Recently,repetitive transcranial magnetic stimulation(rTMS)has attracted interest because of its potential therapeutic value.Aim To investigate the efficacy and safety of rTMS treatment for GAD.Methods Literature studies published in English or Chinese were screened in 10 electronic databases up to 5 December 2018.The included studies'bias risk was assessed using Cochrane risk of bias assessment tool.Meta-analysis was performed to compute the standardised mean difference(SMD)and risk ratio(RR)along with its 95%Cis through using RevMan V.5.3.Heterogeneity was inspected by I2 and the χ2 test.We performed subgroup analysis and meta-regression to investigate heterogeneity.We used funnel plot to assess publication bias.We used the GRADE approach to assess the whole quality of evidence.Results Twenty-one studies,with a total sample size of 1481,were analysed.The risk of bias in most studies included is moderate,the majority of which are lacking of blinding methods of treatment allocation.The treatment had beneficial effects in the rTMS group compared with the control group in mean anxiety score(SMD=-0.68;95%Cl-0.89 to-0.46).None of the 21 studies included here reported severe adverse events.As for dropout rates,there are no statistically significant differences between the two groups(RR 1.14,95%Cl 0.72 to 1.82)or adverse events(RR 0.95,95%Cl 0.77 to 1.18).No particular influence on the heterogeneity of any variable was observed.The risk of publication bias was low.According to the GRADE approach,the evidence levels of primary outcome(treatment effects)and secondary outcomes(acceptability and safety)were rated as‘medium’.Conclusion The use of rTMS combined with medication treatment may have a significant positive anti-anxiety effect on patients with GAD.However,we should interpret the results cautiously due to the relatively high heterogeneity of the meta-analysis.Future high-quality clinical trials are needed to confirm our results. | Huiru Cui Lijuan Jiang Yanyan Wei Wei Li Hui Li Junjuan Zhu Jiaoyan Pang Jijun Wang Chunbo Li | 2019 | General Psychiatry2019，32，5： | 5 |
| 6 | Activated Carbon from Rice Husk with One-Step KOH Mechanical Mixing Activation as Adsorbent for Treating Phenolic Wastewater显示文摘This study investigates how large-surface-area biocarbons with high phenolic adsorption capacities can be obtained from cheap and abundant rice husk(RH).The RH is directly mixed with potassium hydroxide(KOH)and activated in a flowing N_(2) atmosphere,and the effects of the pyrolysis temperature and KOH to RH ratio on the structure of the obtained activated carbon adsorbents and their adsorption of p-nitrophenol and phenol are studied.The results show that the optimum pyrolysis temperature of RH is 750℃,whereby the highest surface area of 2047 m^(2)/g and best adsorption performance are obtained with a KOH to RH ratio of 3:1.Moreover,the obtained biocarbons achieve a maximum adsorption capacity of 175 mg/g for phenol and 430 mg/g for p-nitrophenol,which are higher than most previously reported data. | Jiang Bolong Jiang Nan Shi Shunjie Cui Yanyan | 2022 | China Petroleum Processing & Petrochemical Technology2022，24，4： | 2 |
| 7 | Epitope variation in the Newcastle disease virus HN gene under antibody immune selective pressure in cell culture显示文摘The influence of antibody immune selective pressure on Newcastle disease virus (NDV) HN and F gene mutations was studied in cell cultures.NDV field strain TZ060107 was inoculated into chicken embryo fibroblast cells and continuously passaged with (group A) or without (group B) anti-NDV monospecific serum.Each group contained three independent passage series.HN and F genes were amplified and sequenced for the 10th,20th,30th,40th and 50th generations of each serial passage,and compared with the original strain.The results demonstrated that increased HN gene mutations were observed in group A with the antibody than in group B without the antibody.The nonsynonymous (NS) to synonymous (S) mutations ratio was 6 for group A,significantly higher than 3.4 in group B.In group A with the antibody,there were five stable NS mutations in HN gene,three of which (related to aa#353,521 and 568) were related to known epitopes.There were two stable NS mutations in F gene in group A,but no stable NS mutations in group B.The NS/S ratios of F gene were less than 2.5 for both groups A and B.Our results suggested that the antibody strongly influenced HN gene mutations,while the F gene was less influenced by the same antibody. | GONG YanYan CUI ZhiZhong | 2011 | Science China(Life Sciences)2011，54，5： | 2 |
| 8 | Enhancement of Fe3O4/Au Composite Nanoparticles Catalyst in Oxidative Degradation of Methyl Orange Based on Synergistic Effect显示文摘Fe 3 O 4/Au nanoparticles (Fe 3 O 4/Au NP ) 催化剂被采用 H 2 O 2 作为氧化剂。评估 Fe 3 O 4/Au nanoparticles,不同降级条件被调查例如催化剂的数量, H 2 O 2 集中和 pH 价值。基于我们的数据,甲基橘子在一短时间完全被降级。提高的催化活动和增加的氧化率常数可以被归功于到 synergistic H 2 O 2 到哦激进,它是强壮的氧化种类之一。而且, Fe 3 O 4/Au nanoparticles 展出了令人满意为潜在的工业申请再循环性能。 | Qin Gao Yan Xing Mingli Peng Yongshuai Liu Zhiyi Luo Yanyan Jin Haiming Fan Kebin Li Chao Chen Yali Cui | 2017 | Chinese Journal of Chemistry2017，35，9： | 2 |
| 9 | High entropy fluorides as conversion cathodes with tailorable electrochemical performance显示文摘With the recent development of high entropy materials, an alternative approach to develop advanced functional materials with distinctive properties that show improved values compared to conventional materials has been provided. The high entropy concept was later successfully transferred to metal fluorides and high entropy fluorides(HEFs) were successfully synthesized. Owing to their high theoretical specific capacities in energy storage applications, HEFs were utilized as cathode materials for lithiumion batteries(LIBs) and their underlying storage mechanisms were investigated. Instead of a step-bystep reduction of each individual metal cation, the HEFs seem to exhibit a single-step reduction process,indicating a solid solution compound instead of merely a mixture of different metal fluorides. It was also observed that the electrochemical behavior of the HEFs depends on each individual incorporated element. Therefore, by altering the elemental composition, new materials that exhibit improved electrochemical properties can be designed. Remarkably, HEFs with seven incorporated metal elements exhibited a better cycling stability as well as a lower hysteresis compared to binary metal fluorides.These findings offer new guidelines for material design and tailoring towards high performance LIBs. | Yanyan Cui Parvathy Anitha Sukkurji Kai Wang Raheleh Azmi Alexandra MNunn Horst Hahn Ben Breitung Yin-Ying Ting Piotr MKowalski Payam Kaghazchi Qingsong Wang Simon Schweidler Miriam Botros | 2022 | Journal of Energy Chemistry2022，31，9： | 2 |
| 10 | Inhibition of Breast Cancer Resistance Protein(BCRP) by Ko143 Can Affect Pharmacokinetics of Enrofloxacin in Exopalaemon carinicauda显示文摘Adenosine triphosphate-binding cassette transporter breast cancer resistance protein(BCRP) exists highly in the apical membranes of epithelia, and is involved in drug availability. Ko143 is a typical inhibitor of BCRP in rodents. The synthetic antibacterial agent enrofloxacin(ENRO) is a fluoroquinolone employed as veterinary and aquatic medicine, and also a substrate for BCRP. BCRP gene highly expressed in the hepatopancreas and intestine of Exopalaemon carinicauda as was determined with real-time quantitative reverse transcription-polymerase chain reaction(RT-q PCR) method. The effects of Ko143 on the abundance of BCRP m RNA and ENRO pharmacokinetics in E. carinicauda were studied. The m RNA abundance of BCRP decreased significantly in hepatopancreas and intestine(P < 0.05) after Ko143 treatment. Co-administration of Ko143 significantly changed the pharmacokinetics of orally administered enrofloxacin, which was supported by higher distribution half-life(t_(1/2α)), elimination half-life(t_(1/2β)), area under the curve up to the last measurable concentration(AUC_(0-t)), peak concentration(C_(max)) and lower clearance(CL/F). These findings revealed that Ko143 downregulates BCRP expression in hepatopancreas and intestine, thus affects the pharmacokinetics of orally administered enrofloxacin in E. carinicauda. The drug-drug interaction can be caused by the change in BCRP activity if ENRO is used in combination with other drugs in shrimp. | ZHAI Qianqian XU Yang LI Cuiping FENG Yanyan CUI Yanting MA Li LI Jian | 2020 | Journal of Ocean University of China2020，19，5： | 2 |
| 11 | Design of sustained-release nitrendipine microspheres having solid dispersion structure by quasi-emulsion solvent diffusion method显示文摘 | Fude Cui Mingshi Yang Yanyan Jiang | 2003 | Journal of Controlled Release2003，97，3： | 1 |
| 12 | The Development of Lexical Seman- tic Autonomy of English Majors显示文摘 | CUI YANYAN | 2014 | Chinese Journal of Applied Linguisties2014，，2： | 1 |
| 13 | In vitro antifungal activity of baicalin against Candida albicans biofilms via apoptotic induction显示文摘 | TianMing Wang GaoXiang Shi Jing Shao DaQiang Wu YuanYuan Yan MengXiang Zhang YanYan Cui ChangZhong Wang | 2015 | Microbial Pathogenesis2015，，： | 1 |
| 14 | An uhrasensitive electrochemical immunosensor for the detection of salbutamol based on Pd @ SBA- 15 and ionic liquid显示文摘 | Cui Zhentao Cai Yanyan Wu Dan | 2012 | Electrochimica Acta2012，69，： | 1 |
| 15 | Co_(2)N Nanoparticles Anchored on N-Doped Active Carbon as Catalyst for Oxygen Reduction Reaction in Zinc–Air Battery显示文摘The development of efficient catalytic electrode toward oxygen reduction reaction(ORR)is still a great challenge for the wide use of zinc–air batteries.Herein,Co_(2)N nanoparticles(NPs)anchored on N-doped carbon from cattail were verified with excellent catalytic performances for ORR.The onset and half-wave potentials over the optimal catalyst reach to 0.96 V and 0.84 V,respectively.Current retention rates of 96.8%after 22-h test and 98.8%after running 1600 s were obtained in 1 M methanol solution.Density functional theory simulation proposes an apparently increased electronic states of Co_(2)N in N-doped carbon layer close to the Fermi level.Higher charge density,favorable adsorption,and charge transfer of intermediates originate from the coexistence of Co_(2)N NPs and N atoms in carbon skeleton.The superior catalytic activity of composites also was confirmed in zinc–air batteries.This novel catalytic property and controllable preparation approach of Co_(2)Ncarbon composites provide a promising avenue to fabricate metal-containing catalytically active carbon from biomass. | Xianli Wu Guosheng Han Hao Wen Yanyan Liu Lei Han Xingyu Cui Jiajing Kou Baojun Li Jianchun Jiang | 2022 | Energy & Environmental Materials2022，5，3： | 1 |
| 16 | Effect of COD level andHRT on microbial community in a yeast-predominant activatedsludge system 显示文摘 | Hui Han Yanyan Zhang Cancan Cui | 2010 | Bioresource Technology2010，101，10： | 1 |
| 17 | Reactivity ratios and sequence structures of the copolymers prepared using photo-induced copolymerization of MMA with MTMP显示文摘 | Liu Xiaoxuan Zhang Y origtao Cui Yanyan | 2012 | Magn Reson Chern2012，50，： | 1 |
| 18 | New Subclasses of Biholomorphic Mappings and the Modified Roper-Suffridge Operator显示文摘The authors propose a new approach to construct subclasses of biholomorphic mappings with special geometric properties in several complex variables. The RoperSuffridge operator on the unit ball B^n in C^n is modified. By the analytical characteristics and the growth theorems of subclasses of spirallike mappings, it is proved that the modified Roper-Suffridge operator [Φ_(G,γ)(f)](z) preserves the properties of S_Ω~*(A, B), as well as strong and almost spirallikeness of type β and order α on B^n. Thus, the mappings in S_Ω~*(A, B), as well as strong and almost spirallike mappings, can be constructed through the corresponding functions in one complex variable. The conclusions follow some special cases and contain the elementary results. | Chaojun WANG Yanyan CUI Hao LIU | 2016 | Chinese Annals of Mathematics,Series B2016，37，5： | 1 |
| 19 | Micro-RNA-128 ( miRNA- 128 ) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation显示文摘 | Jingang Cui Yang Zhao Sethi Prahlad K Yanyan Li Mahta All Culicehia Frank Lukiw Waiter J | 2010 | Journal of Neurooncology2010，98，3： | 1 |
| 20 | Effect of Shufeng Jiedu capsules as a broad-spectrum antibacterial显示文摘 | Yanyan Bao Yingjie Gao Xiaolan Cui | 2016 | Bio Science Trends Advance Publication2016，10，1： | 1 |
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