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| 1 | Hot Granules Medium Pressure Forming Process of AA7075 Conical Parts显示文摘High strength aluminum alloy plate has a low elongation at room temperature, which leads to the forming of its components need a high temperature. Liquid or gas is used as the pressure-transfer medium in the existing flexible mould forming process, the heat resistance of the medium and pressurizing device makes the application of aluminum alloy plate thermoforming restricted. To solve this problem, the existing medium is replaced by the heat-resisting solid granules and the general pressure equipments are applied. Based on the pressure-transfer performance test of the solid granules medium, the feasibility that the assumption of the extended Drucker-Prager linear model can be used in the finite element analysis is proved. The constitutive equation, the yield function and the theoretical forming limit diagram(FLD) of AA7075 sheet are established. Through the finite element numerical simulation of hot granules medium pressure forming(HGMF) process, not only the influence laws of the process parameters, such as forming temperature, the blank-holder gap and the diameter of the slab, on sheet metal forming performance are discussed, but also the broken area of the forming process is analyzed and predicted, which are coincided with the technological test. The conical part whose half cone angle is 15° and relative height H/d0 is 0.57, is formed in one process at 250℃. The HGMF process solves the problems of loading and seal in the existing flexible mould forming process and provides a novel technology for thermoforming of light alloy plate, such as magnesium alloy, aluminium alloy and titanium alloy. | DONG Guojiang ZHAO Changcai PENG Yaxin LI Ying | 2015 | Chinese Journal of Mechanical Engineering2015，28，3： | 15 |
| 2 | QUADRATIC OPTIMIZATION METHOD AND ITS APPLICATION ON OPTIMIZING MECHANISM PARAMETER显示文摘以便设计的机制与最佳的动力学行为满足 kinematics 的要求,一个二次的优化方法基于运动学、动态的优化的不同特征被建议。这个方法包括优化的二步,也就是说运动学、动态的优化。同时,它把运动学的优化的结果用作动态优化的限制方程。这个方法在与显著意义与 high-speedrice 幼苗 transplanter 的椭圆形的行星的齿轮移植机制的参数优化被使用。参数光谱,相遇到运动学的要求,在 kinematics 优化通过设想的人机相互作用被获得,并且最佳的参数在动态优化基于改进基因算法被获得。在动态优化,客观功能作为 theoptimal1 被选动态行为,限制方程从运动学的优化的结果。当两个都运动学、动态的表演充当客观功能时,这个方法对多客观的优化合适。 | ZHAO Yun CHEN Jianneng YU Yaxin YU Gaohong ZHU Jianping | 2006 | Chinese Journal of Mechanical Engineering2006，19，4： | 14 |
| 3 | Adsorption of mixed cationic-nonionic surfactant and its effect on bentonite structure显示文摘The adsorption of cationic-nonionic mixed surfactant onto bentonite and its effect on bentonite structure were investigated.The objective was to improve the understanding of surfactant behavior on clay mineral for its possible use in remediation technologies of soil and groundwater contaminated by toxic organic compounds.The cationic surfactant used was hexadecylpyridinium bromide(HDPB),and the nonionic surfactant was Triton X-100(TX100).Adsorption of TX100 was enhanced significantly by the addition of HDPB,but this enhancement decreased with an increase in the fraction of the cationic surfactant.Part of HDPB was replaced by TX100 which decreased the adsorption of HDPB.However,the total adsorbed amount of the mixed surfactant was still increased substantially,indicating the synergistic effect between the cationic and nonionic surfactants.The surfactant-modified bentonite was characterized by Brunauer-Emmett-Teller specific surface area measurement,Fourier transform infrared spectroscopy,and thermogravimetric-derivative thermogravimetric/differential thermal analyses.Surfactant intercalation was found to decrease the bentonite specific surface area,pore volume,and surface roughness and irregularities,as calculated by nitrogen adsorption-desorption isotherms.The co-adsorption of the cationic and nonionic surfactants increased the ordering conformation of the adsorbed surfactants on bentonite,but decreased the thermal stability of the organobentonite system. | Yaxin Zhang Yan Zhao Yong Zhu Huayong Wu Hongtao Wang Wenjing Lu | 2012 | Journal of Environmental Sciences2012，24，8： | 12 |
| 4 | Changes of Precipitation Infiltration Recharge in the Circumstances of Coal Mining Subsidence in the Shen-Dong Coal Field,China显示文摘煤采矿沉淀是在采矿区域的一个通用环境地质的问题。由作为研究领域选择 Shen 盾煤采矿沉淀区域,这篇论文在降水渗入学习变化再装在这种情况下借助于领域的煤采矿沉淀,地质的调查和实验室模拟试验,它被期望在采矿区域为 eco 环境的恢复提供一个科学基础。结果显示在沉淀的不稳定的阶段,在 Shen 盾采矿区域的沉淀的三种类型在降水渗入上有积极效果再装,并且完整厚度的基岩沉淀的类型有最大的影响。在沉淀,在长期的干旱以后的降水渗入进程和在通风地区的潮湿移植的稳定的阶段经历三个不同阶段:在降水前的蒸发渗入,渗入向上的渗入渗入在在降水以后的降水和蒸发渗入期间。在一个重降雨渗入过程期间,在好沙,粗糙的沙和罚款粗糙的沙的二元的结构的弄湿的前面运动由二个阶段组成:在降水,弄湿的前面运动距离与深度在有线性关系期间弄湿前面运动的阶段,和在降水,弄湿的前面运动距离与深度在有力量功能关系以后弄湿前面运动的阶段。弄湿的前面运动速度被降雨数量和岩性学在通风地区影响。作为深度增加,然而,运动速度将指数地腐烂。 | ZHANG Fawang SONG Yaxin ZHAO Hongmei HAN Zhantao WANG Dong | 2012 | Acta Geologica Sinica(English Edition)2012，86，4： | 11 |
| 5 | Advances in alternating electromagnetic field data processing for earthquake monitoring in China显示文摘The alternating electromagnetic(EM) field is one of the most sensitive physical fields related to earthquakes. There have been a number of publications reporting EM anomalies associated with earthquakes. With increasing applications and research of artificial-source extremely low frequency EM and satellite EM technologies in earthquake studies, the amount of observed data from the alternating EM method increases rapidly and exponentially, so it is imperative to develop suitable and effective methods for processing and analyzing the influx of big data. This paper presents research on the self-adaptive filter and wavelet techniques and their applications to analyzing EM data obtained from ground measurements and satellite observations, respectively. Analysis results show that the self-adaptive filter method can identify both natural- and artificial-source EM signals, and enhance the ratio between signal and noise of EM field spectra, apparent resistivity, and others. The wavelet analysis is capable of detecting possible correlation between EM anomalies and seismic events. These techniques are effective in processing and analyzing massive data obtained from EM observations. | ZHAO GuoZe BI YaXin WANG LiFeng HAN Bing WANG Xiao XIAO QiBin CAI JunTao ZHAN Yan CHEN XiaoBin TANG Ji WANG JiJun | 2015 | Science China Earth Sciences2015，58，2： | 7 |
| 6 | Mining coterie patterns from Instagram photo trajectories for recommending popular travel routes显示文摘 | Yaxin YU Yuhai ZHAO Ge YU Guoren WANG | 2017 | Frontiers of Computer Science2017，11，6： | 5 |
| 7 | Human rhinovirus C infection is associated with asthma in children determined by x TAG respiratory viral panel FAST显示文摘Dear Editor,Cumulative evidence supports the role of early-life viral infections,especially respiratory syncytial virus(RSV)and human rhinovirus(HRV),as major antecedents of childhood asthma(Lemanske,2002;Jackson et al.,2008).In this study,the x TAG respiratory viral panel FAST(RVP FAST)assay,a multiplex polymerase chain reaction(PCR)-based method(Arens et al.,2010;BaladaLlasat et al.,2011;Gharabaghi et al.,2011;Selvaraju,2012),was used to investigate the association of infec- | Dongmei Chen Qinwei Song Runan Zhu Yuan Qian Yu Sun Jie Deng Fang Wang Yaxin Ding Run Tian Chuanhe Liu Wenjing Zhu Linqing Zhao | 2017 | Virologica Sinica2017，32，2： | 5 |
| 8 | Distributed Real-time State Estimation for Combined Heat and Power Systems显示文摘This paper proposes a distributed real-time state estimation(RTSE)method for the combined heat and power systems(CHPSs).First,a difference-based model for the heat system is established considering the dynamics of heat systems.This heat system model is further used along with the power system steady-state model for holistic CHPS state estimation.A cubature Kalman filter(CKF)-based RTSE is developed to deal with the system nonlinearity while integrating both the historical and present measurement information.Finally,a multi-timescale asynchronous distributed computation scheme is designed to enhance the scalability of the proposed method for largescale systems.This distributed implementation requires only a small amount of information exchange and thus protects the privacy of different energy systems.Simulations carried out on two CHPSs show that the proposed method can significantly improve the estimation efficiency of CHPS without loss of accuracy compared with other existing models and methods. | Tingting Zhang Wen Zhang Qi Zhao Yaxin Du Jian Chen Junbo Zhao | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，2： | 5 |
| 9 | In situ observation of C_(60)(C(COOH)_(2))_(2) interacting with living cells using fluorescence microscopy显示文摘The interactions between nanoparticles and living cells were investigated by an imaging technique of fluorescence microscopy. For this pur- pose, the C60 derivative C60(C(COOH)2)2, a thera- peutic agent for degeneration diseases of central nervous system, was synthesized, purified and characterized. Its interaction with the living cell and penetration of the cellular membrane were in situ studied using the real time imaging technique, and its potential cytotoxicity was also examined by flow cy- tometry. The results indicate that C60(C(COOH)2)2 can easily enter cells, and is mainly located in cytoplasm by fluorescein labeling. Furthermore, C60(C(COOH)2)2 can carry the molecule that cannot cross cellular membranes into cells, because fluo- rescein compound itself cannot enter the cell or ad- here to membrane. At concentrations ranging from 1×10?2 to 1×102 mg/L, C60(C(COOH)2)2 does not show any detectable cytotoxicity. | YE Chang CHEN Chunying CHEN Zhen MENG Huan XING Li JIANG Yaxin YUAN Hui XING Gengmei ZHAO Feng ZHAO Yuliang CHAI Zhifang FANG Xiaohong HAN Dong CHEN Long WANG Chen WEI Taotao | 2006 | Chinese Science Bulletin2006，51，9： | 4 |
| 10 | Multicenter phaseⅡstudy of apatinib single or combination therapy in HER2-negative breast cancer involving chest wall metastasis显示文摘Objective:Breast cancer(BC)with chest wall metastasis(CWM)usually shows rich neovascularization.This trial explored the clinical effect of apatinib on human epidermal growth factor receptor 2(HER2)-negative advanced BC involving CWM.Methods:This trial involved four centers in China and was conducted from September 2016 to March 2020.Patients received apatinib 500 mg/d[either alone or with endocrine therapy if hormone receptor-positive(HR+)]until disease progression or unacceptable toxicity.Progression-free survival(PFS)was the primary endpoint.Results:We evaluated 26 patients for efficacy.The median PFS(mPFS)and median overall survival(mOS)were4.9[range:2.0-28.5;95%confidence interval(95%CI):2.1-8.3]months and 18(range:3-55;95%CI:12.9-23.1)months,respectively.The objective response rate(ORR)was 42.3%(11/26),and the disease-control rate was76.9%(20/26).In the subgroup analysis,HR+patients compared with HR-negative patients had significantly improved mPFS of 7.0(95%CI:2.2-11.8)months vs.2.3(95%CI:1.2-3.4)months,respectively(P=0.001);and mPFS in patients without or with chest wall radiotherapy was 6.4(95%CI:1.6-19.5)months vs.3.0(95%CI:1.3-4.6)months,respectively(P=0.041).In the multivariate analysis,HR+status was the only independent predictive factor for favorable PFS(P=0.014).Conclusions:Apatinib was highly effective for BC patients with CWM,especially when combined with endocrine therapy.PFS improved significantly in patients with HR+status who did not receive chest wall radiotherapy.However,adverse events were serious and should be carefully monitored from the beginning of apatinib treatment. | Huiping Li Cuizhi Geng Hongmei Zhao Hanfang Jiang Guohong Song Jiayang Zhang Yaxin Liu Xinyu Gui Jing Wang Kun Li Zhongsheng Tong Fangyuan Zhao Junlan Yang Guoliang Chen Qianyu Liu Xu Liang | 2021 | Chinese Journal of Cancer Research2021，33，2： | 4 |
| 11 | Earthquake Electromagnetic Precursor Anomalies Detected by a New Ground-based Observation Network显示文摘It is a debated topic if there are any observable precursor anomalies prior to the earthquake(EQ hereafter)and if the stronger EQ can be successfully predicted.During last few decades quite a lot of observable electromagnetic(EM)precursors were published by using techniques equipped in either satellites or on ground-based stations.But there are only a few cases that the shortterm precursor anomalies of EM field before earthquakes were observed by using alternate EM fields on ground.This paper will present a new EM observation network built in recent years and show a new finding of EM field with the variation of a one-year cycle observed using the network.As an example,the short-term precursor anomalies of apparent resistivity before the Yangbi EQ(Ms 5.1)occurred on March 27,2017 in Yunnan Province will be studied.The observed anomalous phenomena indicate that the anomaly before the EQ can be captured only if reasonable effective methods including sophisticated analytical techniques are used,and it is believed that continuously observed data on the fixed observation network for a long time is an effective means for studying anomalies that appeared before earthquakes.This network can also play an important role in studying the EM environment from space. | Bing HAN Guoze ZHAO Lifeng WANG Ji TANG Yaxin BI Yan ZHAN Xiaobin CHEN Qibin XIAO Jihong ZHANG | 2021 | Journal of Geodesy and Geoinformation Science2021，4，1： | 3 |
| 12 | Identifi cation of egg protein-derived peptides as xanthine oxidase inhibitors:virtual hydrolysis,molecular docking,and in vitro activity evaluation显示文摘The purpose of this study was to screen the xanthine oxidase(XO)inhibitory peptides from egg white proteins through virtual hydrolysis,in vitro activity validation,and molecular docking.The results demonstrated that tripeptide EEK from ovalbumin exhibited potent XO inhibitory activity with an IC50 value of 141μmol/L.The molecular docking results showed that tripeptide EEK bound with the active center of XO via 3 carbon hydrogen bond interactions,2 salt bridges,5 conventional hydrogen bond interactions,and 4 attractive charge interactions.The residues Glu802,Phe1009,and Arg880 may play key roles in the XO catalytic reaction.Especially,the key intermolecular forces of inhibiting XO activity may be special type of hydrogen bonds including carbon hydrogen bond interactions and attraction charge interactions.The novel tripeptide EEK is potential candidates for controlling hyperuricemia. | Zhipeng Yu Yaxin Cao Ruotong Kan Huizhuo Ji Wenzhu Zhao Sijia Wu Jingbo Liu David Shiuan | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 13 | Involvement of MyoD and PEA3 in regulation of transcription activity of MDR1 gene显示文摘在癌症的 multidrug 抵抗 1 的 Overexpression (MDR1 ) 为化疗的失败仍然是主要原因之一。在现在的学习,我们发现 MyoD 和 PEA3 能激活 P-glycoprotein (P-gp ) 在 SGC7901 房间的表示。MyoD 和 PEA3 击倒稀释了 MDR1 表示并且增加了 multidrug 的敏感抵抗癌症房间到被 P-gp 在 SGC7901/VCR 房间搬运的细胞毒素的药。MyoD 或 PEA3 能在 MDR1 倡导者上绑在电子盒子和 PEA3 地点并且激活它的抄写。由 MyoD 和 PEA3 的 MDR1 表示的规定可以提供潜在的方法在癌症治疗克服 MDR。 | Yaxin Zhao Jiefan Liu Qi Hong Chen Yang Li Chen Ying Chen Qiaoqiao Wang Kuaile Zhao Wei Jin | 2010 | Acta Biochimica et Biophysica Sinica2010，42，12： | 3 |
| 14 | Electrochemical characterization and microstructure of cold sprayed AA5083/Al_(2)O_(3) composite coatings显示文摘This work focused on the role of Al_(2)O_(3) particles in the corrosion behavior of cold sprayed AA5083 aluminum alloy matrix composite(Al-MMC)coatings.The electrochemical characterization of the coatings was investigated in a 3.5 wt.%NaCl solution as a function of time.The results show that fragmentation of Al_(2)O_(3) particles is not clearly observed in the case of AA5083/20 vol.%Al_(2)O_(3) coating,while the broken Al_(2)O_(3) particles can be seen clearly in AA5083/40 vol.%Al_(2)O_(3) and AA5083/60 vol.%Al_(2)O_(3) coatings.The addition of 20 vol.%Al_(2)O_(3) particles yield the coating with the lowest porosity,and different volume fractions of Al_(2)O_(3)in the feedstock have important effects on the electrochemical behavior of composite coatings.The Al-MMC coating reinforced with 20 vol.%Al_(2)O_(3) particles exhibits the highest Ecorrand the lowest icorrcompared with the other conditions.The order of current density is as follows:AA5083/20vol.%Al_(2)O_(3) | Xiawei Yang Wenya Li Siqi Yu Yaxin Xu Kaiwei Hu Yaobang Zhao | 2020 | Journal of Materials Science & Technology2020，59，24： | 3 |
| 15 | Stimuli-responsive photofunctional materials for green and security printing显示文摘Information recording on paper has always been the most important approach to keep records of human activity and to spread civilization.With the progress of science and technology,paper with different functions should be exploited to conform to the increasing demands in various scenarios.In one aspect,traditional paper can only be used once,and using large amounts of paper causes deforestation,additional solid waste treatment,environmental pollution,and high energy consumption.Consequently,the development of rewritable paper that is environment-friendly,low cost,and can save resources is significant for green printing.In the other aspect,information leakage brings security issues,which may lead to severe consequences,such as war outbreak,economic loss,social problems,and so on.Therefore,the development of security printing has also attracted wide interests.Stimuli-responsive photofunctional materials that have reversible variations in absorption or emission in response to changes in the external environmental have a great potential for the achievement of green and security printing.To date,much progress has been made in these research areas.This paper lists different smart materials that respond to various external stimuli,such as light,water,pH,heat,and metal ions,and summarizes the recent advances towards green and security printing.Also,we discuss the current challenges and future directions in this rapidly growing research field.It is expected that this review article will stimulate and guide future studies for the advanced green and security printing. | Yun Ma Yaxin Yu Jiangang Li Shujuan Liu Wei Huang Qiang Zhao | 2021 | InfoMat2021，3，1： | 2 |
| 16 | Simulation of g as flow pattern and separation efficiency in cyclone with conventional single and spiral double inlet configuration显示文摘 | Zhao Bingtao Su Yaxin Zhang G | 2006 | Chemical Engineering Research and Design2006，84，12： | 1 |
| 17 | Numerical simula- tion of effect of inlet configuration on square cyclone separator performance 显示文摘 | Yaxin Su Anqiao Zheng Bingtao Zhao | 2011 | Powder Technology2011，210，3： | 1 |
| 18 | Examination of the Fa screen for rare resistance alleles to Bacillus thuringiensis toxins in the diamondback moth ( Lepidoptera: Plutellidae) 显示文摘 | ZHAO Jiangzhou LI Yaxin COLLINS H L | 2002 | J Econ Entomol2002，95，1： | 1 |
| 19 | Transgenic plants expressing two Bacillus thuringiensis toxins delay insectresistance evolution 显示文摘 | ZHAO Jiangzhou CAO Jun LI Yaxin | 2003 | Nat Biotechnol2003，21，12： | 1 |
| 20 | Ultrasonic Characteristics and Severity Assessment of Lung Ultrasound in COVID-19 Pneumonia:A Retrospective,Observational Study显示文摘The clinical application of lung ultrasound(LS)in the assessment of coronavirus disease 2019(COVID-19)pneumonia severity remains limited,Herein,we investigated the role of LUS imaging in CoVID-19pneumonia patients and the relationship between LUS findings and disease severity.This was a retro-spective,observational study at Tongji Hospital,on 48 recruited patients with COVID-19 pneu-monia,including 32 non-critically ill patients and 16critically ill patients.LUS was performed and the respiratory rate oxygenation(ROX)index,disease severity,and confusion,blood urea nitrogen,respira-tory rate,blood pressure,and age(CURB-65)score were recorded on days 0-7,8-14,and 15-21 after symptomonset.Lung images were divided into 12 regions,and the luS score(0-36 points)was calcu-lated.hestcomputed tomography(CT)scores(0-20 points)were also recorded on days O-7.Coelations between the LUS score,ROX index,and CURB-65 scores were examined.LUS detected COVID-19 pneumonia in 38patients.LUS signs included B lines(34/38,89.5%),consolidations(6/38,15.8%),and pleural effusions(2/38,5.3%).Most cases showed more than one lesion(32/38,84.2%)and involved both lungs(28/38,73.7%).Compared with non-critically ill patients,the LUS scores of critically ill patients were higher(12(10-18)vs 2(0-5),p<0.001).The LUS score showed significant negative cor-relations with the ROX indexon days O-7(r=-0.85,p<0.001),days 8-14(r=-0.71,p<0.001),and days 15-21(r=-0.76,p<0.001)after symptom onset.However,the LUS score was positively correlated with the CT score(r=0.82,p<0.001).The number of patients with LUS-detected lesions decreased from 27 cases(81.8%)to 20 cases(46.5%),and the lus scores significantly decreased from 4(2-10)to 0(0-5),(p<0.001) from days O-7 to 17-21.We conclude that LUS can detect lunglesions in COVID-19 pneumo-nia patients in a portable,real-time,and safe manner.Thus,LUS is helpful in assessing COVID-19 pneu-monia severity in critically ill patients. | Fengxue Zhu Xiujuan Zhao Tianbing Wang Zhenzhou Wang Fuzheng Guo Haiyan Xue Panpan Chang Hansheng Liang Wentao Ni Yaxin Wang Lei Chen Baoguo Jiang | 2021 | Engineering2021，7，3： | 1 |
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