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3篇 您的检索式:作者名="Yaxuan Sun"
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1Comparing containment measures among nations by epidemiological effects of COVID-19显示文摘The coronavirus disease 2019(COVID-19)has evolved to a global pandemic since its inception in December 2019.Countries have responded to the epidemics with different levels of responses and containment measures.Given the unprecedented pressure on nations’healthcare systems and the deaths so far,there is an urgent need to evaluate the effects of the containm ent measures,which would be useful for countries to plan for their responses to counter the first or possibly the second wave of the epidemic.There have been studies for the effects of COVID-19 control measures taken in China on disease transmission and public health interventions for W uhan’s outbreaks[1-4],and W uhan travel ban on the spread of COVID-19 both inside China and internationally[5,6].Jia Gu Han Yan Yaxuan Huang Yuru Zhu Haoxuan Sun Yumou Qiu Songxi Chen 2020National Science Review2020,7,12:4
2Staged angioplasty versus regular carotid artery stenting in patients with carotid artery stenosis at high risk of hyperperfusion:a randomised clinical trial显示文摘Background and purpose Hyperperfusion(HP)is a devastating complication associated with carotid artery stenting(CAS)or endarterectomy.The efficacy and safety of staged angioplasty(SAP)in patients with CAS at high risk of HP remains unclear.We sought to determine whether SAP is superior to regular CAS in patients with high risk of HP.Methods A randomised,multicentre open-label clinical trial with blinded outcome assessment(STEP)was conducted.Patients with severe carotid stenosis at high risk of HP were randomly assigned(1:1)to the SAP or regular CAS group.The primary endpoint was hyperperfusion syndrome(HPS)and intracerebral haemorrhage(ICH)within 30 days after the procedure.Results From November 2014 to January 2017,a total of 64 patients were enrolled in 11 centres.33 patients were allocated to the SAP group and 31 to the regular CAS group.At 30 days,the rate of primary endpoint was 0.0%(0/33)in the SAP group and 9.7%(3/31)in the regular CAS group(absolute risk reduction(ARR),9.7%;95%CI−20.1% to 0.7%;p=0.11).As one of the secondary endpoints,the incidence of HP phenomenon(HPP)was lower in the SAP group than the regular CAS group(0.0%vs 22.6%,ARR,−22.6%;95% CI−36.8%to−10.2%;p=0.04).Conclusion The rate of HPS and ICH was not significantly lower in SAP group;the extended secondary endpoint of HPP,however,significantly reduced,which suggested that SAP may be a safe and effective carotid revascularisation procedure to prevent HP.Dapeng Mo Baixue Jia Huaizhang Shi Yaxuan Sun Qingan Liu Chengzhe Fan Jianping Deng Jinglin Yuan Wei Wu Changchun Jiang Guilian Zhang Hanjun Du Ning Ma Feng Gao Xuan Sun Ligang Song Lian Liu Guangge Peng Yongjun Wang Yilong Wang Zhongrong Miao the STEP Study Group 2021Stroke & Vascular Neurology2021,6,1:3
3Protective Effects of Vitamin E against Oxidative Damage Induced by Aβ(1-40)Cu(Ⅱ)Complexes显示文摘贝它淀粉的肽(贝它)被认为为老年的匾的形成负责,它是 Alzheimer 的疾病(广告)的特点 .Oxidativestress ,每氧化由蛋白质氧化和类脂化合物表明了在另外的改变之中,广告 brain.A 的一个特征种证据的身体在 beta1-40forming 的支持被介绍了在建筑群产生的 CuZn 超级氧化物象dismutase一样绑定 site.Abeta1-40 Cu ( II )绑铜的 oligomeric 建筑群从经由 Cu2+reduction 的 O2 的毒害神经的氢过氧化物( H2O2 ),尽管精确反应机制是不清楚的。 beta1-40 或 Abeta1-40Cu ( II )的毒性当(+) -alpha-tocopherol ( 维生素 E )在数据从版本和 H2O2 的形成证实了的乳酸脱氢酶( LDH )导出的 100 muM.The 的集中作为免费激进的抗氧化剂被增加时,到有教养的主要外皮的神经原的建筑群部分被稀释结果从 MTT 试金。这些调查结果显示到 beta1-40 的那铜绑定能产生 H2O2 的更大的生产,它在质膜和随后的 neuronal 死亡的完整导致一个故障。与维生素 E 对待的组展出了许多更细微的损坏,建议维生素 E 起在保护 neuronal 房间免受机能障碍或死亡的伤害的一个关键作用。Xueling DAI~1 Yaxuan SUN~2 and Zhaofeng JIANG~2 ~1College of Life Science,Capital Normal University,Bejing 100037,China ~2College of Applied Sciences Humanities of Beijing Union University,Beijing 100083,China 2007Acta Biochimica et Biophysica Sinica2007,39,2:1
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