|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Synergism between corn stover and cellulase显示文摘 | Han Yejun Chen Hongzhang | 2007 | Enzyme and Microbial Technology2007，41，5： | 1 |
| 2 | Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx^(−/−)mice显示文摘Tendon heterotopic ossification(HO)is characterized by bone formation inside tendon tissue,which severely debilitates people in their daily life.Current therapies fail to promote functional tissue repair largely due to our limited understanding of HO pathogenesis.Here,we investigate the pathological mechanism and propose a potential treatment method for HO.Immunofluorescence assays showed that the Mohawk(MKX)expression level was decreased in human tendon HO tissue,coinciding with spontaneous HO and the upregulated expression of osteochondrogenic and angiogenic genes in the tendons of Mkx^(−/−)mice.Single-cell RNA sequencing analyses of wild-type and Mkx^(−/−)tendons identified three cell types and revealed the excessive activation of osteochondrogenic genes during the tenogenesis of Mkx^(−/−)tendon cells.Single-cell analysis revealed that the gene expression program of angiogenesis,which is strongly associated with bone formation,was activated in all cell types during HO.Moreover,inhibition of angiogenesis by the small-molecule inhibitor BIBF1120 attenuated bone formation and angiogenesis in the Achilles tendons of both Mkx mutant mice and a rat traumatic model of HO.These findings provide new insights into the cellular mechanisms of tendon HO and highlight the inhibition of angiogenesis with BIBF1120 as a potential treatment strategy for HO. | Junxin Lin Yuwei Yang Wenyan Zhou Chao Dai Xiao Chen Yuanhao Xie Shan Han Huanhuan Liu Yejun Hu Chenqi Tang Varitsara Bunpetch Dandan Zhang Yishan Chen Xiaohui Zou Di Chen Wanlu Liu Hongwei Ouyang | 2022 | Bone Research2022，10，4： | 1 |
| 3 | Synergism between hydrophobic proteins of corn stover and cellulase in lignocellulose hydrolysis显示文摘 | YeJun Han HongZhang Chen | 2009 | Biochemical Engineering Journal2009，，2： | 1 |
| 4 | A β-xylosidase fromcell wall of maize:Purification,properties andits use in hydrolysis of plant cell wall显示文摘 | Yejun Han Hongzhang Chen | 2010 | Journal of Molecular Catalysis B:Enzymatic2010，63，34： | 1 |
| 5 | Simultaneous saccharifieation and fermentation of steam exploded wheat straw pretreated with alkaline peroxide 显示文摘 | Chen I-Iongzhang Han Yejun Xu Jian | 2008 | Process Biochemistry2008，43，12： | 1 |
| 6 | Characterization ofβ-glucosidase from corn stover and its application in simul-taneous saccharification and fermentation显示文摘 | HAN Yejun CHEN Hongzhang | 2008 | Biore-source Technology2008，99，14： | 1 |
| 7 | Synergism between corn stover protein and cellulase显示文摘 | Han Yejun Chen Hongzhang | | 0，，： | 1 |
| 8 | Green carbon science:fundamental aspects显示文摘Carbon energy has contributed to the creation of human civilization,and it can be considered that the configuration of the carbon energy system is one of the important laws that govern the operation of everything in the universe.The core of the carbon energy system is the opposition and unity of two aspects:oxidation and reduction.The operation of oxidation and reduction is based on the ternary elemental system composed of the three elements of carbon,hydrogen and oxygen.Its operation produces numerous reactions and reaction products.Ancient Chinese philosophy helps us to understand in depth the essence of green carbon science,to explore its scientific basis,and to identify the related platforms for technology development. | Mingyuan He Kun Zhang Yejun Guan Yuhan Sun Buxing Han | 2023 | National Science Review2023，10，9： | 1 |
| 9 | Characterization of[beta]-glucosidase from corn stover and its application in simultaneous saccharification and fermentation显示文摘 | Han Yejun Chen Hongzhang | | 0，，14： | 1 |
| 10 | Biochemical characterization of a novel thermostable GH11 xylanase with CBM6 domain from Caldicellulosiruptor kronotskyensis显示文摘 | Weibo Qiao Shuge Tang Shuofu Mi Xiaojing Jia Xiaowei Peng Yejun Han | 2014 | Journal of Molecular Catalysis. B, Enzymatic2014，，： | 1 |
| 11 | Simultaneous saccharification and fermentation of steam exploded wheat straw pretreated with alkaline peroxide显示文摘 | Chen Hongzhang Han Yejun Xu Jian | 2008 | Process Biochemistry2008，43，： | 1 |
| 12 | Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem cell transplantation:PAH risk score显示文摘Skin and soft tissue infections(SSTIs)refer to infections involving the skin,subcutaneous tissue,fascia,and muscle.In transplant populations with hematological malignancies,an immunocompromised status and the routine use of immunosuppressants increase the risk of SSTIs greatly.However,to date,the profiles and clinical outcomes of SSTIs in hematopoietic stem cell transplantation(HSCT)patients remain unclear.This study included 228 patients(3.67%)who developed SSTIs within 180 days after allogeneic HSCT from January 2004 to December 2019 in Peking University People’s Hospital.The overall annual survival rate was 71.5%.We compared the differences between survivors and non-survivors a year after transplant and found that primary platelet graft failure(PPGF),comorbidities of acute kidney injury(AKI),and hospital-acquired pneumonia(HAP)were independent risk factors for death in the study population.A PPGF-AKI-HAP risk stratification system was established with a mortality risk score of 1×PPGF+1×AKI+1×HAP.The areas under the curves of internal and external validation were 0.833(95%CI 0.760–0.906)and 0.826(95%CI 0.715–0.937),respectively.The calibration plot revealed the high consistency of the estimated risks,and decision curve analysis showed considerable net benefits for patients. | Shan Chong Yun He Yejun Wu Peng Zhao Xiaolu Zhu Fengrong Wang Yuanyuan Zhang Xiaodong Mo Wei Han Jingzhi Wang Yu Wang Huan Chen Yuhong Chen Xiangyu Zhao Yingjun Chang Lanping Xu Kaiyan Liu Xiaojun Huang Xiaohui Zhang | 2022 | Frontiers of Medicine2022，16，6： | 0 |
| 13 | Highly Emissive Luminogens in Both Solution and Aggregate States显示文摘Organic light-emitting materials have attracted considerable attention because of their promising applications in diverse areas.Most fluorophores emit brightly in either dilute solutions or aggregate states;the former generally suffer from aggregation-caused quenching problem,and the latter encounter intensity loss at low concentrations.Herein,we propose a new strategy to overcome these dilemmas by balancing the planar and distorted structures of terphenyl-based luminogens and obtain three luminogens,2PB-AC,2Me2PB-AC,and 2T2PB-AC,with bright emission in both solution and aggregate states.Among them,2PB-AC shows absolute photoluminescence quantum yields(ФPL)higher than 90%in both tetrahydrofuran solution(90.2%)and aggregate states(92.7%for powder and 95.3%for crystal).Thus,2PB-AC could be an efficient probe to realize dual-channel explosive detection in both solution and aggregate states.Moreover,it could be used to image live-cell lipid droplets at a wide range of concentrations.In addition,benefiting from its thermodynamically favorable intersystem crossing process,2Me2PB-AC could be doped in polymethyl methacrylate matrix to provide efficient room-temperature phosphorescence.Thus,this work provides a feasible strategy for the design of luminogens with highly efficient emission in both solution and aggregate states,greatly facilitating and broadening their practical applications. | Pengbo Han Guiquan Zhang Jia Wang Yejun Yao Yanping Qiu He Xu Anjun Qin Ben Zhong Tang | 2023 | CCS Chemistry2023，5，7： | 0 |
| 14 | Solvent-stabilized few-layer violet phosphorus and its ultrafast nonlinear optics显示文摘Featured with high thermal decomposition temperature and layered structure,violet phosphorus(VP)offers an unparalleled stable allotrope of phosphorus to demonstrate the optoelectronic device and photonics elements with high performance at the nanoscale.Here,we report few-layer and hundreds of nanometer-sized VP with robust stability in different solvents and ambient conditions by ultrasound-assisted liquid phase exfoliation approach.For the first time,the ultrafast carrier dynamics and thirdorder nonlinear optical response of VP were investigated.Sub-picosecond timescale ultrafast carrier dynamic and ultrafast nonlinear saturable absorption of VP were demonstrated.Our findings demonstrated that VP possessed a promising potential for use in ultrafast nonlinear photonic applications such as saturable absorbers and optical switches. | Li Zhou Jianlong Kang Yulan Dong Yiduo Wang Yejun Li Han Huang Si Xiao Yingwei Wang Jun He | 2023 | Nano Research2023，16，4： | 0 |
| 15 | Directional Routing Algorithm for Deep Space Optical Network显示文摘With the development of science, economy and society, the needs for research and exploration of deep space have entered a rapid and stable development stage. Deep Space Optical Network(DSON) is expected to become an important foundation and inevitable development trend of future deepspace communication. In this paper, we design a deep space node model which is capable of combining the space division multiplexing with frequency division multiplexing. Furthermore, we propose the directional flooding routing algorithm(DFRA) for DSON based on our node model. This scheme selectively forwards the data packets in the routing, so that the energy consumption can be reduced effectively because only a portion of nodes will participate the flooding routing. Simulation results show that, compared with traditional flooding routing algorithm(TFRA), the DFRA can avoid the non-directional and blind transmission. Therefore, the energy consumption in message routing will be reduced and the lifespan of DSON can also be prolonged effectively. Although the complexity of routing implementation is slightly increased compared with TFRA, the energy of nodes can be saved and the transmission rate is obviously improved in DFRA. Thus the overall performance of DSON can be significantly improved. | Lei Guo Xiaorui Wang Yejun Liu Pengchao Han Yamin Xie Yuchen Tan | 2017 | China Communications2017，14，1： | 0 |
| 16 | 2D Nb_(2)CT_(x) MXene/MoS_(2) heterostructure construction for nonlinear optical absorption modulation显示文摘Two-dimensional(2D)nonlinear optical mediums with high and tunable light modulation capability can significantly stimulate the development of ultrathin,compact,and integrated optoelectronics devices and photonic elements.2D carbides and nitrides of transition metals(MXenes)are a new class of 2D materials with excellent intrinsic and strong light-matter interaction characteristics.However,the current understanding of their photo-physical properties and strategies for improving optical performance is insufficient.To address this issue,we rationally designed and in situ synthesized a 2D Nb_(2)C/MoS_(2) heterostructure that outperforms pristine Nb2C in both linear and nonlinear optical performance.Excellent agreement between experimental and theoretical results demonstrated that the Nb_(2)C/MoS_(2) inherited the preponderance of Nb_(2)C and MoS_(2) in absorption at different wavelengths,resulting in the broadband enhanced optical absorption characteristics.In addition to linear optical modulation,we also achieved stronger near infrared nonlinear optical modulation,with a nonlinear absorption coefficient of Nb_(2)C/MoS_(2) being more than two times that of the pristine Nb_(2)C.These results were supported by the band alinement model which was determined by the X-ray photoelectron spectroscopy(XPS)experiment and first-principal theory calculation.The presented facile synthesis approach and robust light modulation strategy pave the way for broadband optoelectronic devices and optical modulators. | Yiduo Wang Yingwei Wang Yulan Dong Li Zhou Jianlong Kang Ning Wang Yejun Li Xiaoming Yuan Zhengwei Zhang Han Huang Mengqiu Long Si Xiao Jun He | 2023 | Opto-Electronic Advances2023，6，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员