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| 1 | IncR26319/miR-2834/EndophilinA axis regulates oogenesis of the silkworm,Bombyx mori显示文摘Oocyte maturation is critical for insect reproduction.Vitellogenesis,the timely production and uptake of vitellogenin(Vg),is crucial for female fecundity.Vg is synthesized in fat body and absorbed by the oocytes through endocytosis during insect oogenesis.In the silkworm,Bombyx mori,we discovered that a nucleus-enriched long-noncoding RNA(lncRNA)lncR26319 regulates Endophilin A(EndoA)-a member of the endophilin family of endocytic proteins-through competitive binding to miR-2834.The lncR26319-miR-2834-EndoA axis was required for Vg endocytosis in the silkworm;loss of EndoA or overexpression ofmiR-2834significantlyreduced eggnumbers invirginmoths.Inaddition,accumulation of miR-2834 resulted in pupal and adult deformation and reduced fecundity in females.The expression of Vg,30-kDa(30K)protein,and egg-specific protein(Esp)decreased after knockdown of EndoA or overexpression of miR-2834,while knockdown of miR-2834 had an opposite effect on the expression of Vg,30K protein gene,and Esp.These results suggest that the lncR26319-miR-2834-EndoA axis contributes to the endocytic activity in theVguptake and leads to the normal progression of oogenesis in the silkworm.Thus,miR-2834 and EndoA are crucial for female reproduction and could be potential targets for new pest management strategies in lepidopterans. | Yi Wang Yu Fu Hao Chena Chenyue Zhao Qunxia Huang Meiling Chang Wujie Qiu Yawen Shen Dandan Li | 2023 | Insect Science2023，30，1： | 1 |
| 2 | Expression of insulin - like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells 显示文摘 | Jing Zhanga Yi Lia Jieli Chena | 2004 | Brain Res2004，1030，1： | 1 |
| 3 | Synthesis and characterization of organic - inorganic hybrid thin films from poly(acrylic) and monodispersed colloidal silica 显示文摘 | Yang - Yen Yua Ching - Yi Chena Wen -Chang Chen | 2003 | Polymer2003，44，： | 1 |
| 4 | Simple and efficient method of calibrating a motorized zoom lens显示文摘 | Yong - Sheng Chena Sheng - Wen Shih Yi - Ping Hung | 2001 | Image and Vision Computing2001，19，： | 1 |
| 5 | Quantitative measurement of motor and somatosensory impairments after mild (30min) and severe (2h) transient middle cerebral artery occlusion in rats 显示文摘 | Li Zhanga Jieli Chena Yi Lia | 2000 | Neurological Sciences2000，174，： | 1 |
| 6 | Acquired Cardiomyopathy Caused by Cardiac Tsc1 Deficiency显示文摘Cardiomyopathies are myocardial disorders with enlarged,thick,or rigid cardiac muscles.Because no effective treatment is available to prevent the deterioration of the myocardium function,the prognosis of cardiomyopathy is usually poor.Cardiomyopathies can be inherited or acquired.A number of genes associated with inherited cardiomyopathy,such as the genes encoding for sarcomeric,cytoskeletal,nuclear membrane,lysosomal,desmosomal and mitochondrial proteins, | Yi Chena Fang Wang Chunjia Li Lianmei Wang Hongbing Zhang Hongbing Yan | 2014 | Journal of Genetics and Genomics2014，41，2： | 0 |
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