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| 1 | Deformation reinforcement theory and its application to high arch dams显示文摘In this paper,the deformation reinforcement theory(DRT) proposed by the authors is elaborated with a new definition of instability that an elasto-plastic structure is not stable if it cannot satisfy simultaneously equilibrium condition,kinematical admissibility and constitutive equations under the prescribed loading.Starting from the definition,a proof is established to the principle of minimum plastic complementary energy for failured structures.It is revealed that the principle of mini-mum plastic complementary energy results in relaxed constitutive equations,especially,yield conditions.It is demonstrated with case studies that many key issues in arch dam design,e.g.,global stability,dam-toe reinforcement,dam-toe cracking,dam-abut-ment reinforcement,can be well solved within the framework of the deformation reinforcement theory.The structural global stability can be described by the curve of the plastic complementary energy vs overloading factor.The unbalanced-forces obtained by elasto-plastic FEM can be used as the basis of analysis of global stability,dam-heel cracking,dam-toe anchorage and reinforcement of faults of high arch dams and their foundations. | YANG Qiang,LIU YaoRu,CHEN YingRu & ZHOU WeiYuan State Key Laboratory of Hydroscience and Hydraulic Engineering,Tsinghua University,Beijing 100084,China | 2008 | Science China(Technological Sciences)2008，51，S2： | 21 |
| 2 | Genesis of the Bangbu Orogenic Gold Deposit, Tibet: Evidence from Fluid Inclusion, Stable Isotopes, and Ar-Ar Geochronology显示文摘The Bangbu gold deposit is a large orogenic gold deposit in Tibet formed during the AlpineHimalayan collision. Ore bodies(auriferous quartz veins) are controlled by the E-W-trending Qusong-Cuogu-Zhemulang brittle-ductile shear zone. Quartz veins at the deposit can be divided into three types: pre-metallogenic hook-like quartz veins, metallogenic auriferous quartz veins, and postmetallogenic N-S quartz veins. Four stages of mineralization in the auriferous quartz veins have been identified:(1) Stage S1 quartz+coarse-grained sulfides,(2) Stage S2 gold+fine-grained sulfides,(3) Stage S3 quartz+carbonates, and(4) Stage S4 quartz+ greigite. Fluid inclusions indicate the oreforming fluid was CO_2-N_2-CH_4 rich with homogenization temperatures of 170–261°C, salinities 4.34–7.45 wt% Na Cl equivalent. δ^(18)Ofluid(3.98‰–7.18‰) and low δDV-SMOW(-90‰ to-44‰) for auriferous quartz veins suggest ore-forming fluids were mainly metamorphic in origin, with some addition of organic matter. Quartz vein pyrite has δ^(34)SV-CDT values of 1.2‰–3.6‰(an average of 2.2‰), whereas pyrite from phyllite has δ^(34)SV-CDT 5.7‰–9.9‰(an average of 7.4‰). Quartz vein pyrites yield 206Pb/204 Pb ratios of 18.662–18.764, 207Pb/204 Pb 15.650–15.683, and ^(208)Pb/204 Pb 38.901–39.079. These isotopic data indicate Bangbu ore-forming materials were probably derived from the Langjiexue accretionary wedge. 40Ar/39 Ar ages for sericite from auriferous sulfide-quartz veins yield a plateau age of 49.52 ± 0.52 Ma, an isochron age of 50.3 ± 0.31 Ma, suggesting that auriferous veins were formed during the main collisional period of the Tibet-Himalayan orogen(~65–41 Ma). | PEI Yingru SUN Qingzhong ZHENG Yuanchuan YANG Zhusen LI Wei HUANG Kexian | 2016 | Acta Geologica Sinica(English Edition)2016，90，2： | 12 |
| 3 | Potential of Pteris vittata L. for phytoremediation of sites co-contaminated with cadmium and arsenic: The tolerance and accumulation显示文摘领域调查和温室实验被进行学习 Pteris vittata L 的忍耐。(中国刹车) 到镉(Cd ) 和它为重新调停的可行性,地点与 Cd 和砷共同污染(作为) 。结果显示出那 P。vittata 能在与 Cd 的 80 mg/kg 刺并且容忍的壶土壤幸存象全部的 Cd 的 301 mg/kg 和 diethyltriaminepenta 醋酸(DTPA ) 的 26.8 mg/kg 一样大在地条件下面的可引出的 Cd。在复叶的 Cd 的最高的集中在这个领域里是在 920 mg As/kg 和 98.6 mg Cd/kg 的全部的土壤集中下面的 186 mg/kg,而就在温室下面的 2.6 mg/kg 调节。P 的生态型。vittata 在 Cd 的忍耐和累积被区分,并且他们中的一些不能仅仅高容忍土壤 Cd 的集中,而且在他们的复叶的 Cd 的积累的高集中。由 P 的砷举起和交通。vittata 没在底层被禁止(≤ 20 mg/kg ) Cd 增加。没有 Cd 的增加,比作处理,集中被 103.8% 在 20 mg Cd/kg 增加的复叶,与 6434 mg/kg 的高水平。结果建议了 P 的 Cd 容忍的生态型。是有效地提取的 vittata 和从这个地点的 Cd 与 Cd 并且作为共同污染,并且可能习惯于重新调停并且重新生长这类地点。 | XIAO Xiyuan CHEN Tongbin AN Zhizhuang LEI Mei HUANG Zechun LIAO Xiaoyong LIU Yingru | 2008 | Journal of Environmental Sciences2008，20，1： | 11 |
| 4 | Methods of computed tomography screening and management of lung cancer in Tianjin: design of a population-based cohort study显示文摘Objective: European lung cancer screening studies using computed tomography(CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time(VDT) is more specific for early lung cancer detection than a diameter-based protocol. However, whether this also applies to a Chinese population is unclear. The aim of this study is to compare the diagnostic performance of a volume-based protocol with a diameter-based protocol for lung cancer detection and optimize the nodule management criteria for a Chinese population.Methods: This study has a population-based, prospective cohort design and includes 4000 participants from the Hexi district of Tianjin, China. Participants will undergo low-dose chest CT at baseline and after 1 year. Initially, detected lung nodules will be evaluated for diameter and managed according to a routine diameter-based protocol(Clinical Practice Guideline in Oncology for Lung Cancer Screening, Version 2.2018). Subsequently, lung nodules will be evaluated for volume and management will be simulated according to a volume-based protocol and VDT(a European lung nodule management protocol). Participants will be followed up for 4 years to evaluate lung cancer incidence and mortality. The primary outcome is the diagnostic performance of the European volume-based protocol compared to diameter-based management regarding lung nodules detected using low-dose CT.Results: The diagnostic performance of volume-and diameter-based management for lung nodules in a Chinese population will be estimated and compared.Conclusions: Through the study, we expect to improve the management of lung nodules and early detection of lung cancer in Chinese populations. | Yihui Du Yingru Zhao Grigory Sidorenkov Geertruida H.de Bock Xiaonan Cui Yubei Huang Monique D.Dorrius Mieneke Rook Harry J.M.Groen Marjolein A.Heuvelmans Rozemarijn Vliegenthart Kexin Chen Xueqian Xie Shiyuan Liu Matthijs Oudkerk Zhaoxiang Ye | 2019 | Cancer Biology & Medicine2019，16，1： | 7 |
| 5 | Characteristic Temperatures of Waxy Crude Oils显示文摘Gel point or pour point is widely used to evaluate the low temperature flowability of crude oil. However, it is not adequate to describe the gelling properties of waxy crude oils under flow conditions with gel point or pour point, since the rheological behavior of crude oils is dependent on shear history. Waxy crude oils tend to gel at a low temperature. Based on gelation theory, the characteristic temperature of waxy crude oil was determined by analyzing viscosity-temperature data. Two mathematical models were developed for calculating characteristic temperatures of virgin crude oils and pour point depressants (PPD) beneficiated crude oils, respectively. By using these two models, the characteristic temperatures of crude oils that have experienced shearing and thermal histories can be predicted. The model for predicting the characteristic temperature of virgin crude oils has an average relative deviation of 4.5%, and all predicted values have a deviation within 2 ℃. Tested by 42 sets of data, the prediction model for crude oil treated with PPD has a high accuracy, with an average relative deviation of 4.2%, and 95.2 percent of predicted values have a deviation within 2 ℃. These two models provide useful ways for predicting the flowability of crude oils in pipelines when only wax content, wax appearance point and gel point are available. | Zhu Yingru Zhang Jinjun Li Hongying Chen Jun | 2007 | Petroleum Science2007，4，3： | 6 |
| 6 | Clinical characteristics and work-up of small to intermediate-sized pulmonary nodules in a Chinese dedicated cancer hospital显示文摘Objectives:To evaluate the characteristics and work-up of small to intermediate-sized pulmonary nodules in a Chinese dedicated cancer hospital.Methods:Patients with pulmonary nodules 4–25 mm in diameter detected via computed tomography(CT)in 2013 were consecutively included.The analysis was restricted to patients with a histological nodule diagnosis or a 2-year follow-up period without nodule growth confirming benign disease.Patient information was collected from hospital records.Results:Among the 314 nodules examined in 299 patients,212(67.5%)nodules in 206(68.9%)patients were malignant.Compared to benign nodules,malignant nodules were larger(18.0 mm vs.12.5 mm,P<0.001),more often partly solid(16.0%vs.4.7%,P<0.001)and more often spiculated(72.2%vs.41.2%,P<0.001),with higher density in contrast-enhanced CT(67.0 HU vs.57.5 HU,P=0.015).Final diagnosis was based on surgery in 232 out of 314(73.9%)nodules,166 of which were identified as malignant[30(18.1%)stage III or IV]and 66 as benign.In 36 nodules(11.5%),diagnosis was confirmed by biopsy and the remainder verified based on stability of nodule size at follow-up imaging(n=46,14.6%).Among 65 nodules subjected to gene(EGFR)mutation analyses,28(43.1%)cases(EGFR19 n=13;EGFR21 n=15)were identified as EGFR mutant and 37(56.9%)as EGFR wild-type.Prior to surgery,the majority of patients[n=194(83.6%)]received a contrast-enhanced CT scan for staging of both malignant[n=140(84.3%)]and benign[n=54(81.8%)]nodules.Usage of positron emission tomography(PET)-CT was relatively uncommon[n=38(16.4%)].Conclusions:CT-derived nodule assessment assists in diagnosis of small to intermediate-sized malignant pulmonary nodules.Currently,contrast-enhanced CT is commonly used as the sole diagnostic confirmation technique for pre-surgical staging,often resulting in surgery for late-stage disease and unnecessary surgery in cases of benign nodules. | Xiaonan Cui Daiwei Han Marjolein AHeuvelmans Yihui Du Yingru Zhao Lei Zhang Harry JMGroen Geertruida Hde Bock Monique DDorrius Matthijs Oudkerk Rozemarijn Vliegenthart Zhaoxiang Ye | 2020 | Cancer Biology & Medicine2020，17，1： | 5 |
| 7 | Genesis of the Gold Deposit in the Indus-Yarlung Tsangpo Suture Zone,Southern Tibet:Evidence from Geological and Geochemical Data显示文摘The Nianzha gold deposit,located in the central section of the Indus-Yarlung Tsangpo suture(IYS) zone in southern Tibet,is a large gold deposit(Au reserves of 25 tons with average grade of 3.08 g/t) controlled by a E-W striking fault that developed during the main stage of Indo-Asian collision(~65-41 Ma).The main orebody is 1760 m long and 5.15 m thick,and occurs in a fracture zone bordered by Cretaceous diorite in the hanging wall to the north and the Renbu tectonic melange in the footwall to the south.High-grade mineralization occurs in a fracture zone between diorite and ultramafic rock in the Renbu tectonic melange.The wall-rock alteration is characterized by silicification in the fracture zone,serpentinization and the formation of talc and magnesite in the ultramafic unit,and chloritization and the formation of epidote and calcite in diorite.Quartz veins associated with Au mineralization can be divided into three stages.Fluid inclusion data indicate that the deposit formed from H_2O-NaCl-organic gas fluids that homogenize at temperatures of 203℃-347℃ and have salinities of 0.35wt%-17.17wt%NaCl equivalent.The quartz veins yield δ^(18)O_(fluid) values of 0.15‰-10.45‰,low δD_(V-SMOW)values(-173‰ to-96‰),and the δ^(13)C values of-17.6‰ to-4.7‰,indicating the ore-forming fluids were a mix of metamorphic and sedimentary orogenic fluids with the addition of some meteoric and mantle-derived fluids.The pyrite within the diorite has δ^(34)S_(V-CDT) values of-2.9‰-1.9‰(average-1.1‰),^(206)Pb/^(204)Pb values of 18.47-18.64,^(207)Pb/^(204)Pb values of 15.64-15.74,and ^(208)Pb/^(204)Pb values of 38.71-39.27,all of which are indicative of the derivation of S and other ore-forming elements from deep in the mantle.The presence of the Nianzha,Bangbu,and Mayum gold deposits within the IYS zone indicates that this area is highly prospective for large orogenic gold deposits.We identified three types of mineralization within the IYS,namely Bangbu-type accretionary,Mayum-type microcontinent,and Nianzha-type ophiolite-associated orogenic Au deposits.The three types formed at different depths in an accretionary orogenic tectonic setting.The Bangbu type was formed at the deepest level and the Nianzha type at the shallowest. | ZHANG Xiong DENG Xueguo YANG Zhusen HOU Zengqian ZHENG Yuanchuan LIU Yingchao ZHAO Xiaoyan XU Bo PEI Yingru ZHOU Jinsheng ZHAO Miao YUAN Jianfei | 2017 | Acta Geologica Sinica(English Edition)2017，91，3： | 4 |
| 8 | Fluid Inclusion and Stable Isotope Geochemistry of the Shangxu Gold Deposit, Northern Tibet显示文摘Objective The Shangxu gold deposit is located in the south of the middle Bangong-Nujiang suture zone in northern Tibet.The origin of this deposit as an orogenic gold deposit is debatable.The study of the Shangxu deposit has a profound implication on gold exploration in the BangongNujiang metallogenic belt and can also improve our understanding of gold mineralization in northern Tibet. | PEI Yingru YANG Zhusen ZHAO Xiaoyan ZHANG Xiong MA Wang MAO Jingtao | 2016 | Acta Geologica Sinica(English Edition)2016，90，4： | 2 |
| 9 | A risk-prediction score for colorectal lesions on 12,628 participants at high risk of colorectal cancer显示文摘Background The uptake of colonoscopy is low in individuals at risk of colorectal cancer(CRC).We constructed a riskprediction score(RPS)in a large community-based sample at high risk of CRC to enable more accurate risk stratification and to motivate and increase the uptake rate of colonoscopy.Methods A total of 12,628 participants classified as high-risk according to positivity of immunochemical fecal occult blood tests or High-Risk Factor Questionnaire underwent colonoscopy.Logistic regression was used to derive a RPS and analysed the associations of the RPS with colorectal lesions,giving odds ratios(ORs)and 95%confidence intervals(CIs).Results Of the participants,men(OR=1.73,95%CI=1.58–1.90),older age(≥65 years;1.41,1.31–1.53),higher body mass index(≥28 kg/m^(2);1.22,1.07–1.39),ever smoking(1.47,1.31–1.65),and weekly alcohol use(1.28,1.09–1.52)were associated with a higher risk of colorectal lesions.We assigned 1 point to each of the above five risk factors and derived a RPS ranging from 0 to 5,with a higher score indicating a higher risk.Compared with a RPS of 0,a RPS of 1,2,3,and 4–5 showed a higher risk of colorectal lesions,with the OR(95%CI)being 1.50(1.37–1.63),2.34(2.12–2.59),3.58(3.13–4.10),and 3.91(3.00–5.10),respectively.The area under the receiver-operating characteristic curve of RPS in predicting colorectal lesions was 0.62.Conclusions Participants with an increase in the RPS of≥1 point had a significantly higher risk of colorectal lesions,suggesting the urgency for measuring colonoscopy in this very high-risk group.High-risk strategies incorporating RPS may be employed to achieve a higher colonoscopy-uptake rate. | Lixin Liang Yingru Liang Ke Li Pengzhe Qin Guozhen Lin Yan Li Huan Xu Suixiang Wang Qinlong Jing Boheng Liang Lin Xu | 2022 | Gastroenterology Report2022，10，1： | 2 |
| 10 | Review and outlook on the international renewable energy development显示文摘Renewable energy has become an important choice to solve the energy crisis and environmental problems.A sustainable development needs policies and strategies policies,which can improve energy efficiency and reduce greenhouse gas emissions.By collecting the research results released by relevant statistical departments and authoritative institutions,this paper summarizes the international energy development situation,systematically combs the energy development situation of the European Union,United States,Australia,India,Brazil.The development trend of wind,solar,biomass,geothermal,ocean,and hydrogen energy have been analyzed.In addition,this paper proposes that China should draw up its own development path of renewable energy from international development experience,and actively explore renewable energy policies and strategies adapted to different stages of development. | Li Li Jian Lin Nianyuan Wu Shan Xie Chao Meng Yanan Zheng Xiaonan Wang Yingru Zhao | 2022 | Energy and Built Environment2022，3，2： | 2 |
| 11 | Development and Prospects for Energy Saving Technology in Oil & Gas Fields,China显示文摘Current state of energy saving technology in China's oil and gas fields System optimization To optimize the oil-gas field surface engineering system is critical to improve the efficiency of oil and gas field system.To adapt to the changes in development of old oil and gas fields,all oilfields are adjusted and reconstructed;a set of optimized and simplified modes and technical measures are developed. | Chen Youwang Yu Jiqing Lin Ran Zhu Yingru Liu Feijun | 2010 | China Oil & Gas2010，17，4： | 2 |
| 12 | Activation of the bitter taste sensor TRPM5 prevents high saltinduced cardiovascular dysfunction显示文摘High salt intake is a known risk factor of cardiovascular diseases. Our recent study demonstrated that long-term high salt intake impairs transient receptor potential channel M5(TRPM5)-mediated aversion to high salt concentrations, consequently promoting high salt intake and hypertension;however, it remains unknown whether TRPM5 activation ameliorates cardiovascular dysfunction. Herein we found that bitter melon extract(BME) and cucurbitacin E(CuE), a major compound in BME, lowered high salt-induced hypertension. Long-term BME intake significantly enhanced the aversion to high salt concentrations by upregulating TRPM5 expression and function, eventually decreasing excessive salt consumption in mice. Moreover, dietary BME ameliorated high salt-induced cardiovascular dysfunction and angiotensin II-induced hypertension in vivo. The mechanistic evidence demonstrated that dietary BME inhibited high salt-induced RhoA/Rho kinase pathway overactivation, leading to reduced phosphorylation levels of myosin light chain kinase and myosin phosphatase targeting subunit 1. Furthermore, CuE inhibited vasoconstriction by attenuating L-type Ca^(2+) channel-induced Ca^(2+) influx in vascular smooth muscle cells. To summarize, our findings indicate that dietary BME has a beneficial role in antagonizing excessive salt consumption and thus appears promising for the prevention of high salt-induced cardiovascular dysfunction. | Hao Wu Yuanting Cui Chengkang He Peng Gao Qiang Li Hexuan Zhang Yanli Jiang Yingru Hu Xiao Wei Zongshi Lu Tianyi Ma Daoyan Liu Zhiming Zhu | 2020 | Science China(Life Sciences)2020，63，11： | 2 |
| 13 | Expression profiling identifies genes expressed early during lint fibre initiation in cotton显示文摘 | Wu Yingru Adriane C M Rosemary G W | 2006 | Plant and Cell Physiology2006，47，1： | 1 |
| 14 | Stability and reinforcement analyses of high arch dams by considering deformation effects显示文摘The strict definition and logical description of the concept of structure stability and failure are presented. The criterion of structure stability is developed based on plastic complementary energy and its variation. It is presented that the principle of minimum plastic complementary energy is the combination of structure equilibrium, coordination condition of deformation and constitutive relationship. Based on the above arguments, the deformation reinforcement theory is developed. The structure global stability can be described by the relationship between the global degree of safety of structure and the plastic complementary energy. Correspondingly, the new idea is used in the evaluations of global stability, anchorage force of dam-toe, fracture of dam-heel and treatment of faults of high arch dams in China. The results show that the deformation reinforcement theory provides a uniform and practical theoretical framework and a valuable solution for the analysis of global stability, dam-heel cracking, dam-toe anchorage and reinforcement of faults of high arch dams and their foundations. | Qiang Yang Yaoru Liu Yingru Chen Weiyuan Zhou | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，4： | 1 |
| 15 | Clinical Significance of hTERC Gene Detection in Exfoliated Cervical Epithelial Cells for Cervical Lesions显示文摘 | Xiuhui Zheng Peihe Liang Yingru Zheng Ping Yi Qiang Liu Jian Han Yinhu Huang Yuanguo Zhou Jianxin Guo Li Li | 2013 | International Journal of Gynecological Cancer2013，，5： | 1 |
| 16 | A high-performance flexible fibre-shaped electrochemical capacitor based on electrochemically reduced graphene oxide显示文摘 | LI Yingru SHENG Kaixuan YUAN Wenjing | 2013 | Chemical Communications2013，49，3： | 1 |
| 17 | The spatial-temporal hierarchy of regional inequality of China显示文摘 | Yingru Li Y.H. Dennis Wei | 2009 | Applied Geography2009，，3： | 1 |
| 18 | On monolithic stability and reinforcement analysis of high arch dams显示文摘Monolithic stability safety and reinforcement based on monolithic stability are very important for arch dam design. In this paper, the issue is addressed based on deformation reinforcement theory. In this approach, plastic complementary energy norm can be taken as safety index for monolithic stability. According to deformation reinforcement theory, the areas where unbalanced force exists require reinforcement, and the required reinforcement forces are just the unbalanced forces with opposite direction. Results show that areas with unbalanced force mainly concentrate in dam-toes, dam-heels and faults. | YANG Qiang CHEN YingRu LIU YaoRu | 2007 | Science China(Technological Sciences)2007，50，z1： | 1 |
| 19 | Clinical significance of hTERC gene detection in exioliated cervical epithelial cells for cervical lesions显示文摘 | Xiuhui Z Peihe L Yingru Z | 2013 | International Journal of Gy necological Cancer2013，23，5： | 1 |
| 20 | Performance analysis andparametric optimum criteria of an irreversible Atkinsonheatengine显示文摘 | ZHAO Yingru CHEN Jincan | 2006 | Applied Energy2006，83，8： | 1 |
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